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3051 - 3100 of 8287 citations for 6 Phenyl 1H imidazo 1 2 b pyrazole since 2019

• A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

  Anniek Zaalberg, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HSP90 (sc-12119, Santa Cruz Biotechnologies, 1:1000) diluted in 4% BSA/PBS-T ...
• Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

  Priyanka Gupta, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H1.5 (Santa Cruz sc-247158; RRID:AB_10847577; 1:1000), P-S988 RBL1 (Bibb Lab ...
• Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

  Weini Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Staining with p65 antibody (1:500, Santa Cruz) was followed by Alexa fluor-568 anti-mouse antibody (1:1000 ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... TPR (Santa Cruz Biotechnology; #sc-101294; 1:1000), KIF4A (Santa Cruz Biotechnology ...
• Illuminating the Terminal Nerve: Uncovering the Link between GnRH-1 and Olfactory Development

  Enrico Amato Jr, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse-α-Calb1 (1:200, Santa Cruz Biotechnology), goat-α-Nqo1 (1:700 ...
• Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

  Yevgeniy V. Serebrenik, et al., bioRxiv - Cell Biology 2023

  Quote: ... GFP (sc-9996, Santa Cruz Biotechnology; 1:1666), alpha-tubulin (NB100-690 ...
• Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

  Xuebin Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-p21 (Santa Cruz Biotechnology, sc397, 1:500), anti-β-ACTIN (Santa Cruz Biotechnology ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-GFP (1:1000; FL Santa Cruz), rabbit anti-l-Afadin (1:500 ...
• DNA methylation insulates genic regions from CTCF loops near nuclear speckles

  Shelby A. Roseman, et al., bioRxiv - Genomics 2023

  Quote: ... GAPDH (1:2000, Santa Cruz Biotechnology sc-47724); Vinculin (1:2000 ...
• Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes

  Laurent Starck, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Fibronectin (Santa Cruz Biotechnology, 1:200 dilution). Primary antibody was incubated overnight at 4°C ...
• Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes

  Laurent Starck, et al., bioRxiv - Neuroscience 2023

  Quote: ... and GAPDH (Santa Cruz Biotechnology, 1:500 dilution). Primary antibodies were incubated overnight in 2.5% BSA in TBST ...
• The Role of Respiratory Complex IV in Lifespan Length and Quality

  Beatriz Castejon-Vega, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p70 S6K (Santa Cruz, sc-230, 1:1,000); phospho-p70 S6K (Cell Signalling ...
• MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed

  Xuanyu Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ELAVL2 (rabbit IgG, 1:100, Santa Cruz), anti-ELAVL2/4 (rabbit IgG ...
• PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

  Payam Gharibani, et al., bioRxiv - Neuroscience 2023

  Quote: ... or mouse anti-iNOS (1:200, Santa Cruz). After the primary antibodies ...
• The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

  Peter D. Szigetvari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GAPDH (#sc-32233 Santa Cruz Biotech; 1:1000) primary antibodies and proteins were detected by incubation at a 1:5000 dilution with secondary horseradish peroxidase (HRP)- conjugated antibodies (#170-6516 ...
• Identification and functional characterization of the putative members of the CTDK-1 kinase complex as regulators of growth and development in the genus Aspergillus

  Z. Agirrezabala, et al., bioRxiv - Microbiology 2023

  Quote: ... or α-HA3x (1:1000; Santa Cruz Biotechnology) mouse monoclonal antibody cocktails ...
• DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

  Seungsoo Kim, et al., bioRxiv - Genomics 2023

  Quote: ... TCF3 (Santa Cruz Biotechnology, sc-133074, 1:50), AP2a (Cell Signaling ...
• Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness

  Inga Viktoria Hensel, et al., bioRxiv - Cell Biology 2023

  Quote: ... or IFIT3 (1:500; Santa Cruz #sc-393512). Signal was detected after incubation with anti-mouse_HRP (1:2000 ...
• mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy

  Lisa Maria Riedmayr, et al., bioRxiv - Bioengineering 2023

  Quote: ... mouse anti-ABCA4 (1:100, 3F4, Santa Cruz) and a custom-made rabbit anti-CNGB1 antibody (1:5000 ...
• Kinetic networks identify Twist2 as a key regulatory node in adipogenesis

  Arun B. Dutta, et al., bioRxiv - Genomics 2022

  Quote: ... HSP90 (Santa Cruz Biotechnology sc-13119, 1:2000), Tubulin (Cell Signaling Technology 2148S 1:2000) ...
• Oxygen-independent, hormonal control of HIF-1α regulates the developmental and regenerative growth of cardiomyocytes

  Amarylis C.B.A. Wanschel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... NKX2-5 (1:50; Santa Cruz Biotechnology, SC8697).
• Identifying transcriptomic downstream targets of genes commonly mutated in Hereditary Hemorrhagic Telangiectasia

  Md Khadem Ali, et al., bioRxiv - Cell Biology 2022

  Quote: ... Id1 (sc133104, monoclonal, Santa Cruz Biotechnology, 1:100) and an HRP-conjugated secondary antibodies (Cat # ab205719 and ab6721 ...
• PTPN1 deficiency modulates BMPR2 signaling and induces endothelial dysfunction in Pulmonary Arterial Hypertension

  Md Khadem Ali, et al., bioRxiv - Cell Biology 2022

  Quote: ... ID1 (Cat # sc-133104, Santa Cruz, 1:100), b-Actin (Cat # SC4778 ...
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... and TOM20 (1:200; Santa Cruz; sc-11415). Cells were washed three times in PBS supplemented with 0,05% Tween20 and subsequently incubated with the corresponding Alexa secondary antibodies (Thermo Fisher Scientific).
• Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier

  Stephanie L. Baringer, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Heph (Santa Cruz, SC-365365, 1:500). Positive and negative controls used for assay optimization can be found in Supplemental Figure 2 ...
• Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes

  Lucia Binó, Lukáš Čajánek, bioRxiv - Cell Biology 2023

  Quote: ... OCT4 (mouse, SC-5279, Santa Cruz, 1:4000), α-TUBULIN (mouse ...
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PML (1:200, sc-966; Santa Cruz Biotechnology), PML (1:500 ...
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ATRX (1:1,000, sc-15408; Santa Cruz Biotechnology), FLAG (1:1,000 ...
• Coordinated growth of linked epithelia is mediated by the Hippo pathway

  Sophia Friesen, Iswar K. Hariharan, bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-Hth (1:50; Santa Cruz Biotechnology), rat anti-E-cad (1:100 ...
• Chromatin remodeling enzyme Snf2h is essential for retinal cell proliferation and photoreceptor maintenance

  Andrea Kuzelova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-S-opsin (Santa Cruz, 1:500), rabbit anti-M-opsin (Santa Cruz ...
• Chromatin remodeling enzyme Snf2h is essential for retinal cell proliferation and photoreceptor maintenance

  Andrea Kuzelova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-M-opsin (Santa Cruz, 1:500), rabbit anti-CENP-A (Cell Signaling ...
• Chromatin remodeling enzyme Snf2h is essential for retinal cell proliferation and photoreceptor maintenance

  Andrea Kuzelova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-cyclin D1 (Santa Cruz, 1:300), rabbit anti-pH3 (Santa Cruz ...
• Matrix Gla Protein acts as a driver of stemness and tumor initiation in ovarian cancer

  V. Nieddu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... α-tubulin (Santa Cruz, cat# sc-32293, 1:1000). Membranes were incubated with IgG HRP-conjugated secondary antibody (Bio-Rad Laboratories ...
• Hsp70/Hsp90 organizing protein (HOP) maintains CRAF kinase activity and regulates MAPK signaling by enhancing Hsp90-CRAF association

  Nilanjan Gayen, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:1000 (Santa Cruz Biotechnology #SC373746, CST #2165S) and their phospho antibodies ...
• Single-cell transcriptomics of adult skin VE-cadherin expressing lineages during hair cycle

  Gopal Chovatiya, et al., bioRxiv - Cell Biology 2023

  Quote: ... Endomucin (1:300, Santa Cruz Biotechnology, sc-65495). The IF images were captured using either the Leica DMI6000B microscope with Leica K5 camera or the Zeiss LSM inverted 880 confocal microscopes ...
• PGM3 inhibition Shows cooperative Effects With Erastin inducing Pancreatic cancer cell death via activation of the Unfolded Protein Response

  Barbara Zerbato, et al., bioRxiv - Cancer Biology 2023

  Quote: ... eIF2α (sc-133127, 1:1000) from Santa Cruz Biotechnology Inc ...
• PGM3 inhibition Shows cooperative Effects With Erastin inducing Pancreatic cancer cell death via activation of the Unfolded Protein Response

  Barbara Zerbato, et al., bioRxiv - Cancer Biology 2023

  Quote: ... NRF2 (sc-13032, 1:1000) from Santa Cruz Biotechnology Inc ...
• TRPM5⁺ microvillous tuft cells regulate neuroepithelial intrinsic olfactory stem cell proliferation

  Saltanat Ualiyeva, et al., bioRxiv - Immunology 2023

  Quote: ... mouse anti-EpCAM (Santa Cruz,1 μg/ml) and rabbit anti-FOXI1 (ThermoFisher,0.5 μg/ml) ...
• TRPM5⁺ microvillous tuft cells regulate neuroepithelial intrinsic olfactory stem cell proliferation

  Saltanat Ualiyeva, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit anti-gustducin (Santa Cruz, 1 μg/ml), rat anti-cochlin (Sigma Millipore ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti Cdc20 (Santa Cruz, sc-13162, 1:400), anti-Golgin-97 (Cell Signaling Technology ...
• Loss of polarity regulators initiates gasdermin E mediated pyroptosis in human maternal fetal interface trophoblasts

  Khushali Patel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-GSDME (1:50; Santa Cruz Biotechnology; sc393162); anti-cleaved caspase-3 Asp175 (1:400 ...
• Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks

  Angelica Barreto-Galvez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cyclin-A(1:500, sc-271682, Santa Cruz), POLD3 (1:1000 ...
• Acute resistance exercise induces mitophagy and mitophagomes on subsarcolemmal clefts in human skeletal muscle: Focus on BNIP3L/NIX40 as a mitophagy flux marker

  F. Díaz-Castro, et al., bioRxiv - Physiology 2023

  Quote: ... Parkin (1:1000, SC-32282, Santa Cruz Biotechnology), BNIP3L (1:1000 ...
• TGFβ controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription

  Danielle A. Callaway, et al., bioRxiv - Cell Biology 2023

  Quote: ... Hopx (mouse, Santa Cruz, sc-398703 1:00), GFP (chicken ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... PHF6 p-tau antibody (Santa Cruz, 1:200), γ-H2AX antibody (Abcam ...
• Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy

  K. Bonnycastle, et al., bioRxiv - Neuroscience 2023

  Quote: ... Goat anti-dynamin-1 (Santa Cruz sc-6402) 1:1000 ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-LAMP1 (1:50; Santa Cruz, sc-19992), and anti-MAP2 (1:500 ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP1A (1:200; Santa Cruz, sc-271617), anti-CHMP2B (1:400 ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-TSG101 (1:200; Santa Cruz, sc-7964), anti-Ubiquitin (1:200 ...
• Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

  Laura M. Pikkupeura, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and Gata4 (Santa Cruz #sc-25310, 1:500).