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151 - 200 of 8129 citations for 4 6 Difluoro 1 methyl 1H indazole 5 carboxylic acid since 2020

• Mitochondrial uncoupling protein 2 (UCP2), but not UCP3, is sensitive to oxygen concentration in cells

  Karolina E. Hilse, et al., bioRxiv - Cell Biology 2020

  Quote: ... Oct 3/4 (Santa Cruz, sc-9081, dilution 1:1500), and VDAC (voltage-dependent anion channel ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... overnight at 4°C: anti-YAP (1:25, Santa Cruz Biotechnology ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse-anti-EEA (1:500, G-4, Santa Cruz Biotechnology), rabbit-GAPDH (1:2000 ...
• miR-183/96/182 cluster is an important morphogenetic factor targeting PAX6 expression in differentiating human retinal organoids

  Lucie Peskova, et al., bioRxiv - Molecular Biology 2020

  Quote: ... or Oct-3/4 (sc-5279, Santa Cruz, 1:400). The cells were then washed and incubated with secondary antibodies antiRabbit or anti-Mouse AlexaFluor 488 (Thermo Fisher Scientific ...
• Meiosis-Specific Cohesin Complexes Display Distinct and Essential Roles in Mitotic ESC Chromosomes

  Eui-Hwan Choi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-mouse OCT3/4 (Santa Cruz; sc-5297; 1:3,000), anti-rat RPA (Cell signaling ...
• “Identification of microRNAs regulated by E2F transcription factors in human pluripotent stem cells”

  María Soledad Rodríguez-Varela, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Anti-OCT-4 (1:1000) primary antibody from Santa Cruz Biotechnology (sc-5279 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-RSK (B-4) (Santa Cruz sc-74575; 1:1000) anti-pS6 Ser235/236 (Cell Signaling 4858 ...
• How scars shape the neural landscape: key molecular mediators of TGF-β1’s anti-neuritogenic effects

  Kye-Im Jeon, Krystel R. Huxlin, bioRxiv - Neuroscience 2020

  Quote: ... and a mouse monoclonal antibody to acetylated α-tubulin (Ac-Tub; 1:5000, 6-11B-1, Santa Cruz Biotechnology). Responsiveness to NGF was assayed by probing for the expression of tropomyosin receptor kinase A (Trk-A ...
• Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

  Jing Zhao, et al., bioRxiv - Cell Biology 2022

  Quote: ... the membrane was incubated for 1h using an appropriate Horseradish Peroxidase (HRP)-conjugated secondary antibody (Santa Cruz Biotechnology) at room temperature ...
• Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension

  Alan de Araujo, et al., bioRxiv - Physiology 2024

  Quote: ... kynurenic acid-D5 and xanthurenic acid-D4 were obtained from Santa Cruz (Dallas, TX), and anthranilic acid-13C6 and xanthurenic acid-D4 were obtained from ISOTEC (St Louis ...
• 2-Guanidino-quinazoline promotes the readthrough of nonsense mutations underlying human genetic diseases

  Laure Bidou, et al., bioRxiv - Molecular Biology 2021

  Quote: ... DO-1 (N-terminal epitope mapping between amino-acid residues 11 and 25 of p53; Santa Cruz Biotechnologies, 1/400) or a monoclonal antibody against mouse actin (Millipore ...
• Activation of STING due to COPI-deficiency

  Annemarie Steiner, et al., bioRxiv - Immunology 2020

  Quote: ... Membranes were probed with primary antibody diluted in 5% skim milk/TBST or 5% Bovine Serum Albumin (BSA)/TBST over night at 4°C: anti-COPA (Santa Cruz Biotechnology, clone H-3, sc-398099), anti-phospho-STAT1 Tyr701 (Cell Signaling Technology ...
• Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting

  Xiangyu Gong, et al., bioRxiv - Bioengineering 2023

  Quote: The EC-patches and EC-strips were fixed on Day 5 with 4% Paraformaldehyde (PFA, Santa Cruz Biotechnology) for 10 minutes and then washed with PBS three times ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53(E-5) (1:50, Santa Cruz, sc-74573), p53(DO-1 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p21 (F-5) (1:500, sc-6246, Santa Cruz Biotechnology), Phospho-Stat1 (Tyr701 ...
• Human DICER helicase domain recruits PKR and modulates its antiviral activity

  Thomas C. Montavon, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-TRBP (1:500, D-5 Santa Cruz sc-514124), anti-PKR (1:2500 ...
• Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic

  Hazel Stewart, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-VPS35 (Santa Cruz, B-5, IF 1:300), mouse anti-CD63 (BioLegend ...
• FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1

  Fábio J. Ferreira, et al., bioRxiv - Genetics 2023

  Quote: ... anti-p21 (F-5, sc-6246, Santa Cruz, 1:800) and anti p16INK4a (ab7962 ...
• Gαi2 Interaction with EB1 Controls Microtubule Dynamics and Rac1 Activity in Xenopus Neural Crest Cell Migration

  Soraya Villaseca, et al., bioRxiv - Cell Biology 2024

  Quote: ... Gαi2 (Santa Cruz, L-5, and T-19; 1:50), EB1 (Sigma ...
• Mutant IDH uncouples p53 from target gene regulation to disable tumor suppression

  Cole Martin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p21 (F-5) (1:1000, sc-6246, Santa Cruz Biotechnology), Total Histone H3 (1B1B2 ...
• A genome-wide genetic screen uncovers novel determinants of human pigmentation

  Vivek K. Bajpai, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat SOX10 (1:50; 4°C overnight; Santa Cruz, sc-17342), mouse HMB45 (1:20 ...
• The beta-tubulin isotype TUBB6 controls microtubule and actin dynamics in osteoclasts

  Justine Maurin, et al., bioRxiv - Cell Biology 2021

  Quote: ... or α-tubulin (1:200, YOL3/4 Santa Cruz Biotechnologies sc53030), ARHGAP10 (1:200) ...
• PLD2-phosphatidic acid recruit ESCRT-I to late endosomes for exosome biogenesis

  Antonio Luis Egea-Jimenez, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-CD81 (D-4, sc-166028, Santa Cruz, 1:1000 dilution), anti-flotillin-1 (610820 ...
• Endogenous retroviruses promote prion-like spreading of proteopathic seeds

  Shu Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti PiT-2 B-4 (1:1000; Santa Cruz Biotechnology); rabbit anti-V5 D3H8Q (1:1000 ...
• CREB-mediated transcriptional activation of NRMT1 drives muscle differentiation

  John G. Tooley, et al., bioRxiv - Biochemistry 2021

  Quote: ... mouse anti-Elf1 (C-4) (1:1000; sc-133096, Santa Cruz), mouse anti-Ets-1 (C-4 ...
• Rejuvenation of aged oocyte through exposure to young follicular microenvironment

  HaiYang Wang, et al., bioRxiv - Developmental Biology 2024

  Quote: ... mouse anti-Oct3/4 (sc-5279, Santa Cruz Biotechnology; 1:50), rabbit anti–CDX2 (NB100-2136 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-CD9 (dilution 1/500; Santa Cruz Biotechnology; C-4). Secondary antibodies were anti-IgG rabbit (dilution 1/4000 ...
• Endogenously produced hydrogen cyanide serves as a novel mammalian gasotransmitter

  Karim Zuhra, et al., bioRxiv - Biochemistry 2024

  Quote: ... were seeded at 70–80 % confluence in a 6-well plate and transiently transfected 4-6 h later with the TST shRNA plasmid (sc-36418-SH : Santa Cruz Biotechnology Inc., Santa Cruz, CA 95060), a packaging plasmid pLP1 ...
• EPSTEIN-BARR VIRUS LMP1 ENHANCES LEVELS OF MICROVESICLE-ASSOCIATED PD-L1

  Monica Abou Harb, Li Sun, David G. Meckes Jr., bioRxiv - Microbiology 2022

  Quote: ... HSC70 (B-6; Santa Cruz), Caveolin-1 (D46G3 ...
• Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

  YiQing Lü, et al., bioRxiv - Cancer Biology 2022

  Quote: ... FBXO42 (Santa Cruz FL-6), GAPDH HRP-conjugated antibody (BioLegend W17079A) ...
• Persistence of backtracking by human RNA polymerase II

  Kevin B Yang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TCEA1 (B-6; Santa Cruz), B-actin (C4 ...
• Structural basis of interdomain communication in PPARγ

  Sarah A. Mosure, et al., bioRxiv - Biochemistry 2022

  Quote: ... Membranes were blocked in 5% milk and incubated overnight at 4 °C in primary antibody (anti-PPARγ, Santa Cruz #sc-7273 ...
• An Enhancer Trap system to track developmental dynamics in Marchantia polymorpha

  Alan O. Marron, et al., bioRxiv - Plant Biology 2023

  Quote: ... Auxin synthesis inhibitor treatments were done by growing gemmae on plates made with 10µM 5-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol (yucasin) (ChemCruz, Santa Cruz Biotechnology) or 100µM L-kynurenine (Sigma ...
• TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade

  Yan Xiong, et al., bioRxiv - Cell Biology 2023

  Quote: ... antibodies to TrCP1 (C-6) (Cat# sc-390629) (1:1000) and STUB1 (Cat# sc- 133066) (1:1000) were from Santa Cruz; antibodies to V5 (Cat# MCA1360GA ...
• Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems

  Rupsa Datta, et al., bioRxiv - Immunology 2024

  Quote: ... a 30 min pre-incubation with 1 µM pentafluorobenzenesulfonyl fluorescein (Santa Cruz, CAS 728912-45-6) by immersion was included ...
• Engram cell connectivity as a mechanism for information encoding and memory function

  Clara Ortega-de San Luis, et al., bioRxiv - Neuroscience 2023

  Quote: ... 4-hydroxytamoxifen (4-OHT, Santa Cruz) was freshly prepared in oil (mix of sunflower seed oil ...
• Transmembrane helices mediate the formation of a stable ternary complex of cyt b₅ reductase, cyt b₅, and SCD1

  Jiemin Shen, Gang Wu, Ah-Lim Tsai, Ming Zhou, bioRxiv - Biochemistry 2021

  Quote: ... The δ-aminolevulinic acid (Santa Cruz) and/or riboflavin (Sigma ...
• TuNR: Orthogonal Control of Mean and Variability of Endogenous Genes in a Human Cell Line

  Alain R. Bonny, et al., bioRxiv - Synthetic Biology 2020

  Quote: ... and Gibberellic Acid (Santa Cruz Biotechnology) were prepared as individual 4000x stocks (1.6 M and 20 mM ...
• Removal of KCNQ2 from Parvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine

  Junzhan Jing, et al., bioRxiv - Neuroscience 2021

  Quote: Kainic Acid (KA; Santa Cruz Biotechnology) was dissolved in phosphate-buffered saline (PBS ...
• A Fluorescence-Based Sensor for Calibrated Measurement of Protein Kinase Stability in Live Cells

  Joseph W. Paul III, et al., bioRxiv - Biochemistry 2023

  Quote: ... was added to 1% (w/v) along with 2 mM valproic acid (Santa Cruz Biotechnology #sc-202378B) to improve viral gene expression and recovery ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stained using anti-ASC (Santa Cruz, sc22514R, 4 μg.mL-1), Alexa594-goat anti rabbit antibodies (Invitrogen ...
• Role of ERK activation in H. pylori-induced disruption of cell-cell tight junctions

  Amita Sekar, Bow Ho, bioRxiv - Microbiology 2020

  Quote: ... and rabbit polyclonal anti-claudin-4 (1:1000, Santa Cruz Biotechnology, USA) were used in immunofluorescence and immunoblotting experiments respectively ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... ppERK1/2 (E-4) (1/10,000 dilution, #sc-7383, Santa Cruz, Mouse), tERK1/2 (1/10,000 dilution ...
• Mechanisms of insertions at a DNA double-strand break

  Jaewon Min, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-β-Actin (1:1000; C-4, Santa Cruz Biotechnology, sc-47778). anti-rabbit immunoglobulin G (IgG ...
• Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment

  Matteo Villa, et al., bioRxiv - Immunology 2023

  Quote: ... anti-EP4 (encoded by Ptger4, clone C-4, 1:100, Santa Cruz), anti-ATG5 (clone D5F5U ...
• Ehrlichia Wnt short linear motif ligand mimetic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis

  Caitlan D. Byerly, et al., bioRxiv - Microbiology 2023

  Quote: ... α-Yap, α-TEAD(1, 3, and 4)(Santa Cruz Biotechnology, Dallas, TX), α-active β-catenin ...
• Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signaling

  Abigail U. Carbonell, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Arf1 1:1000 (clone ARFS 1A9/5, Santa Cruz #53168), rabbit anti-Arf1 1:1000 (Proteintech #20226-1-AP) ...
• Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection

  Andrew K. Beppu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Rabbit polyclonal anti-Keratin 5 (1:500, Santa Cruz, Sc-66856); Rabbit polyclonal anti IL-22 (1:200 ...
• Myo1f has an essential role in γδT intraepithelial lymphocyte adhesion and migration

  Irving Ulises Martínez-Vargas, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Myo1f (clone B-5, dilution 1:200) (Santa Cruz Biotechnology) and anti-phospho-tyrosine (clone PY20 ...
• APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases

  RC Mazzarino, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti β-catenin (E-5) (1:50, sc-7963, Santa Cruz) and anti-Reelin (CR-50 ...