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151 - 200 of 1704 citations for 4 5 5 5 Tetrafluoro 4 trifluoromethoxy pentan 2 one since 2020

• Mutant IDH uncouples p53 from target gene regulation to disable tumor suppression

  Cole Martin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p21 (F-5) (1:1000, sc-6246, Santa Cruz Biotechnology), Total Histone H3 (1B1B2 ...
• Noncannonical functions of Ku may underlie essentiality in human cells

  Rachel D. Kelly, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Pdcd-4 (B-4, Santa Cruz, 1:1000), and Rabbit α-tubulin (ab15246 ...
• miRNA mediated downregulation of non-muscle Cyclase associated protein 1 is required for myogenic differentiation

  Anurag Kumar Singh, et al., bioRxiv - Cell Biology 2021

  Quote: ... Myosin Heavy chain 1/2/4/6 (1:1000, Santa Cruz), GAPDH (1:3000 ...
• Endogenous retroviruses promote prion-like spreading of proteopathic seeds

  Shu Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti PiT-2 B-4 (1:1000; Santa Cruz Biotechnology); rabbit anti-V5 D3H8Q (1:1000 ...
• scRNA-Sequencing uncovers a TCF-4-dependent transcription factor network regulating commissure development

  Marie-Theres Wittmann, et al., bioRxiv - Genomics 2020

  Quote: ... Germany)] and 2 μl of ms TCF-4-antibody (Santa Cruz, sc393407), 2 μl of ms BrdU-antibody (BD Bioscience ...
• Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

  Gregory C. Howard, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and blocked in 5% milk in TBS-T before incubation overnight with one of the following primary antibodies: anti-p53 (Santa Cruz Biotechnology, Cat# sc-126), anti-RPL22 (Santa Cruz Biotechnology ...
• Dormant replication origin firing links replication stress to whole chromosomal instability in human cancer

  Ann-Kathrin Schmidt, et al., bioRxiv - Cell Biology 2021

  Quote: ... cells were stained with anti-α-tubulin (1:700, B-5-1-2, Santa Cruz, USA, cat no sc-23948), anti-CENP-C (1:1000 ...
• Effects of sheared chromatin length on ChIP-seq quality and sensitivity

  Cheryl A. Keller, et al., bioRxiv - Genomics 2020

  Quote: ... 5 μg of TAL1 antibody (Santa Cruz Biotechnology, sc12984x, lot B2511) or 5 μL of CTCF antiserum (MilliporeSigma ...
• Pro-apoptotic and anti-invasive properties underscore the tumor suppressing impact of myoglobin on subset of human breast cancer cells

  Mostafa A. Aboouf, et al., bioRxiv - Cancer Biology 2022

  Quote: ... mouse anti-p21 (F-5) monoclonal antibody (Santa Cruz, #sc-6246) 1:200 ...
• Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia

  Ricardo Errazquin, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Anti-Cytokeratin 5 antibody was purchased from Santa Cruz (sc-32721). The control experiments without the primary antibody gave no signal.
• Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signaling

  Abigail U. Carbonell, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Arf1 1:1000 (clone ARFS 1A9/5, Santa Cruz #53168), rabbit anti-Arf1 1:1000 (Proteintech #20226-1-AP) ...
• Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection

  Andrew K. Beppu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Rabbit polyclonal anti-Keratin 5 (1:500, Santa Cruz, Sc-66856); Rabbit polyclonal anti IL-22 (1:200 ...
• 14-3-3 shuttles Activity-dependent neuroprotective protein to the cytoplasm to promote appropriate neuronal morphogenesis, cortical connectivity and calcium signaling

  Sarah A. Bennison, et al., bioRxiv - Neuroscience 2020

  Quote: ... Anti-ADNP antibody (Mouse, F-5, Santa Cruz Technology, sc-393377), Anti-Sox2 (Goat ...
• The MKRN1-BRAF exon4-exon9 fusion is a targetable oncogenic driver

  Megan A. Girtman, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Membranes were blocked in 5% Blotto (Santa Cruz Biotechnology, Dallas, TX) for 60 minutes at room temperature and then incubated with the specific antibodies in dilution buffer at 4°C overnight ...
• Attenuation of cGAS/STING Activity During Mitosis

  Brittany L. Uhlorn, et al., bioRxiv - Immunology 2020

  Quote: ... cells were treated with 5 μM nocodazole (Santa Cruz sc-3518), 10 μM golgicide A (Santa Cruz sc-215103) ...
• Myo1f has an essential role in γδT intraepithelial lymphocyte adhesion and migration

  Irving Ulises Martínez-Vargas, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Myo1f (clone B-5, dilution 1:200) (Santa Cruz Biotechnology) and anti-phospho-tyrosine (clone PY20 ...
• APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases

  RC Mazzarino, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti β-catenin (E-5) (1:50, sc-7963, Santa Cruz) and anti-Reelin (CR-50 ...
• Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements

  Max Trauernicht, et al., bioRxiv - Genomics 2023

  Quote: ... CDKN1A (F-5, 1:1000, Santa Cruz Biotechnology, #sc-6246, mouse).
• The NanoLuc Assay System for Accurate Real-Time Monitoring of Mitochondrial Protein Import within Intact Mammalian Cells

  Hope I Needs, et al., bioRxiv - Biochemistry 2022

  Quote: ... 5 mM D-(+)-glucose,10 mM HEPES (Santa Cruz Biotechnology, Germany), 1 mM MgCl2 ...
• p53 enables phospholipid headgroup scavenging

  Jossie J. Yashinskie, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-p21 (F-5) (1:500, Santa Cruz Biotechnology, sc-6246), anti-PCYT2 (1:1000 ...
• Upregulation of FasII underlies synergistic neuropathological and behavioral defects in a Drosophila model of myotonic dystrophy

  Alex Chun Koon, et al., bioRxiv - Neuroscience 2024

  Quote: ... Membranes were blocked in 5% Blotto (Santa Cruz Biotech, sc-2324) diluted in 1X TBS-T (10 mM Tris-HCl ...
• Recruitment of the m⁶A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

  Syed Nabeel-Shah, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 5 μg of IgG (Santa Cruz Biotechnology, catalog number: sc-2025) was used in control IPs ...
• A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

  Chames Kermi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p21 (clone F-5, sc-6246, Santa Cruz Biotechnology; RRID: AB_628073); αtubulin (T6199 ...
• Copper induces p53 unfolding in cancer cells, resulting in invasion and chemoresistance

  Yannick von Grabowiecki, et al., bioRxiv - Cancer Biology 2024

  Quote: ... After blocking with 5% skimmed milk (Marvel) in TBS (Santa Cruz)/ 0.1% Tween20 (Sigma ...
• CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors

  Joel Rüegger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The membranes were then washed three times with TBS-T (5 min) and incubated with secondary goat anti-rabbit-HRP (sc-2030, Santa Cruz, 1:4,000 in 5% (w/v) milk in TBS-T ...
• Development of LRRK2 designed ankyrin-repeat proteins

  Verena Dederer, et al., bioRxiv - Biochemistry 2023

  Quote: ... was blocked in 5% milk for one hour at room temperature and incubated with a monoclonal mouse anti-GFP antibody (Santa Cruz Biotechnology sc-9406, 1:2500), a rabbit anti-pRab8A phospho T72 monoclonal antibody (Abcam 230260 ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... ppERK1/2 (E-4) (1/10,000 dilution, #sc-7383, Santa Cruz, Mouse), tERK1/2 (1/10,000 dilution ...
• Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma

  Hui Si Kwok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Pfeiffer and Karpas-422 were transduced by spinfection at 1,070 x g (5 acceleration, 2 brake) for 90 min at 37 °C with 8 µg/ml polybrene (Santa Cruz Biotechnology). After 48 h post-transduction ...
• Transcriptional changes in Plasmodium falciparum upon conditional knock down of mitochondrial ribosomal proteins RSM22 and L23

  Swati Dass, et al., bioRxiv - Microbiology 2022

  Quote: ... The membrane was blocked with 5% milk/PBS for 2 h before incubation with mouse monoclonal anti-HA antibody (Sc-7392, Santa Cruz) at 1:10,000 for overnight at 4°C ...
• Inhibition of lysyl oxidase-like 2 ameliorates folic acid-induced renal tubulointerstitial fibrosis

  Sung-Eun Choi, et al., bioRxiv - Pathology 2020

  Quote: ... HK-2 cells were treated with media containing 5 μg/ml of polybrene (cat. no. sc-134220; Santa Cruz Biotechnology, Inc.), and then LOXL2 shRNA lentiviral particles and control shRNA lentiviral particles of 1 and 2 multiplicity of infection (MOI ...
• Ankylosis homologue mediates cellular efflux of ATP, not pyrophosphate

  Flora Szeri, et al., bioRxiv - Biochemistry 2021

  Quote: ... and using α-tubulin as a loading control (mouse anti-α-tubulin B-5-1-2, Santa Cruz Biotechnology, Dallas, TX).
• Intercellular telomere transfer extends T cell lifespan

  Bruno Vaz, et al., bioRxiv - Immunology 2020

  Quote: Human T cells (2-5 x 106) were transfected with 3 μg of TERT KO CRISPR/Cas9 plasmid (h) (sc-400316, Santa Cruz) according to the manufacturer instructions ...
• Inhibitory input directs astrocyte morphogenesis through glial GABA_BR

  Yi-Ting Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3mg of nuclear lysates were used for IP with 2 μg IgG or 5 μg primary antibodies (normal mouse IgG, Santa Cruz Biotechnology ...
• Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

  Ashwin R. Iyer, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Transcription factor ChIP-Seq was performed as previously described11 with 2-5 ug of antibody was used per immunoprecipitation (POU2F2, sc-233X, Santa Cruz; POU2AF1 ...
• Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing

  Niek van Bree, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 4-hydroxycyclophosphamide (4-HCP, Santa Cruz Biotechnology, sc-206885A) were added directly in E3 medium to a final concentration of 10 μM ...
• B cell-intrinsic requirement for WNK1 kinase in T cell-dependent antibody responses

  Darryl Hayward, et al., bioRxiv - Immunology 2021

  Quote: ... were coated with 5 μg/ml NP20-BSA (Santa Cruz Biotechnology, Inc.) overnight at 4°C and then washed five times with PBS ...
• LINE-1 activation in the cerebellum drives ataxia

  Takehiro Takahashi, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1200 g in the presence of 5 μg/ml polybrene (Santa Cruz). Forty-eight hours after spinfection ...
• Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

  José Alexandre Salerno, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-Sigma1R B-5 (1:100, SC-137075 - Santa Cruz Biotechnology). The use of the convalescent serum from COVID-19 patients was approved by CAAE number ...
• Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

  Sivasankar Putta, et al., bioRxiv - Biochemistry 2022

  Quote: ... and Anti-OctA-Probe H-5 (Santa Cruz Biotech, sc-166355, RRID:AB_2017593).
• The hallucinogenic serotonin_2A receptor agonist, DOI, promotes CREB-dependent gene expression of specific plasticity-associated genes in the rodent neocortex

  Lynette A. Desouza, et al., bioRxiv - Neuroscience 2021

  Quote: ... or goat anti-5-HT2A receptor (1:500, Santa Cruz Biotechnologies, USA) along with the pan-neuronal marker ...
• Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex

  Peristera Roboti, Craig Lawless, Stephen High, bioRxiv - Biochemistry 2021

  Quote: ... anti-Stx-5 (Santa Cruz Biotechnology sc-365124; 1:500 for IB), anti-TOM20 (Santa Cruz Biotechnology sc- 17764 ...
• Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

  Namgyu Lee, et al., bioRxiv - Biochemistry 2023

  Quote: ... treated with 5 mM Glutamate and/or 3 µM selenide (Santa Cruz). After 12 hr ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... RhoB (sc-8048, Clone 5, 1:1000 dilution, RRID: AB_628219, Santa Cruz), RhoC (3430 ...
• What Strengthens Protein-Protein Interactions: Analysis and Applications of Residue Correlation Networks

  Ta I Hung, et al., bioRxiv - Biophysics 2023

  Quote: ... ISG15-AVTRYVDC was further crosslinked with fluorescein-5-Maleimide (Santa Cruz Biotechnology) at 4 °C for 1 hour ...
• Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer

  Elangoli Ebrahimkutty Faseela, et al., bioRxiv - Genomics 2023

  Quote: ... The membrane was blocked in 5% skimmed milk (Santa Cruz, sc-2324) prepared in 1× TBS-T at RT for 1 hour on the rocker ...
• The Src-family kinase Lyn plays a critical role in establishing and maintaining B cell anergy by suppressing PI3K-dependent signaling

  Brigita E. Fiske, et al., bioRxiv - Immunology 2024

  Quote: ... or 5 μg/mL anti-IgDa (clone AMS 9.1, Santa Cruz Biotechnology) for 2 minutes ...
• The Src-family kinase Lyn plays a critical role in establishing and maintaining B cell anergy by suppressing PI3K-dependent signaling

  Brigita E. Fiske, et al., bioRxiv - Immunology 2024

  Quote: ... or 5 μg/mL anti-IgDa (clone AMS 9.1, Santa Cruz Biotechnology) for the indicated time ...
• A nucleosome switch primes Hepatitis B Virus infection

  Nicholas A. Prescott, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and then incubated with anti-HBcAg antibody (C1-5, Santa Cruz Biotechnology) diluted in MAXpack Immunostaining Media Kit (Active Motif ...
• SCAN1 mutant TDP1 blocks the repair of DSB induced by TOP1 activity during gene transcription and promotes genome reorganisations and cell death in quiescent cells

  Diana Rubio-Contreras, et al., bioRxiv - Genetics 2024

  Quote: ... 5% BSA and employed as follows: TDP1 (Santa Cruz B, sc-365674) 1:250 ...
• SRY-Box Transcription Factor 9 regulates 3’-Phosphoadenosine 5’-Phosphosulfate Synthase 2 mRNA expression through derepression of the transcriptional repressor, CCAAT/enhancer-binding protein beta

  Cunren Liu, Rosa Serra, bioRxiv - Molecular Biology 2024

  Quote: ... Membranes were blocked with 3-5% milk (Santa Cruz Biotechnology, # sc-2325). Membranes were then incubated overnight with anti-sox9 primary antibody (1:1000 ...