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1651 - 1700 of 2396 citations for 2H Pyrazolo 4 3 c pyridine 3 chloro 4 5 6 7 tetrahydro since 2020

• Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice

  Yuexia Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Primary antibodies were mouse monoclonal anti-lamin A/C (Santa Cruz) at 1:1,000 dilution and rat monoclonal anti-prelamin A clone 3C8 (56 ...
• The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

  Edward T. Parkin, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-Jagged1 C-terminal goat polyclonal antibody was from Santa Cruz Biotechnology Inc ...
• Optical nanoscopy reveals SARS-CoV-2-induced remodeling of human airway cells

  Wilco Nijenhuis, et al., bioRxiv - Cell Biology 2021

  Quote: ... Mouse anti-Centriolin antibody (C-9, Santa Cruz Biotechnology, sc-365521), mouse anti-dsRNA (J2 ...
• Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

  Anna J. Bowen, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-c-Fos (1:500, Santa Cruz Biotechnology, sc-52), chicken-anti-GFP (1:10000 ...
• Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome

  Beatriz Marcos-Ramiro, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... anti-lamin A/C (Santa Cruz Biotechnology, sc-376248, 1:500) and anti-GAPDH (Cell Signaling ...
• The RNA-binding protein RBP45D of Arabidopis plays a role in epigenetic control of flowering time and DCL3-independent RNA-directed DNA methylation

  Liangsheng Wang, et al., bioRxiv - Plant Biology 2021

  Quote: ... or c-Myc (Santa Cruz Biotechnology, Dallas TX, USA, sc-40), the membrane was washed for 4 × 10 min with 1× TBST (50 mM Tris·HCl [pH 7.5] ...
• Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy

  Silvia Peripolli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-c-Myc (Santa Cruz Biotechnology 9E10 sc-40 1:1000), anti-CHK1 (Cell Signalling Technology 2360 1:1000) ...
• The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent neural stem cells tumor formation

  Emmanuel Gallaud, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-PKCζ (C-20) (rabbit, 1:250, Santa Cruz sc-216), anti-Miranda (rat ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin A/C (Santa Cruz, sc-376248, 1/500) and mouse anti-lamin A/C (Santa Cruz ...
• The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells

  A.F.J. Janssen, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-lamin A/C (Santa Cruz, #sc-7292, 1/500), mouse anti-lamin B1 (Santa Cruz ...
• Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

  Emily S. Bell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Lamin A/C (N-18) (1/50, Santa Cruz Biotechnologies, AB_648152), Lamin A (H102 ...
• Characterisation of the Renal Cortical Transcriptome Following Roux-en-Y Gastric Bypass Surgery in Experimental Diabetic Kidney Disease

  Meera Nair, et al., bioRxiv - Molecular Biology 2020

  Quote: ... (antibody C-19, sc-192 Santa Cruz Biotechnology, 1:250 dilution) and desmin (Antibody Clone Dako.Cytomation 1:100 dilution ...
• Heterodimers of functionally divergent ARF-GEF paralogues prevented by self-interacting dimerisation domain

  Sabine Brumm, et al., bioRxiv - Plant Biology 2021

  Quote: ... mouse anti-LexA mAb C-11 (Santa Cruz Biotechnology sc-390386), 1:1000 ...
• Bassoon controls synaptic vesicle pools via regulation of presynaptic phosphorylation and cAMP homeostasis

  Carolina Montenegro-Venegas, et al., bioRxiv - Neuroscience 2021

  Quote: ... PKAα cat (C-20) (WB:1:500, # sc-903, Santa Cruz), pSer145PDE4B (WB 1:200 ...
• Keratin 17 regulates nuclear morphology and chromatin organization

  Justin T. Jacob, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse monoclonal anti-lamin A/C (Santa Cruz REF# sc-376248), mouse anti-lamin B1/B2 (“2B2” ...
• Classic oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer

  Ayushi S. Patel, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The membranes were immunoblotted with anti-c-Myc (Santa Cruz Biotechnology), anti-L-Myc (Proteintech) ...
• Photoreceptor Compartment-Specific TULP1 Interactomes

  Lindsey A. Ebke, et al., bioRxiv - Cell Biology 2021

  Quote: ... ubiquitous mitochondrial creatine kinase (uMtCK C-18, Santa Cruz, 1:500), synaptophysin (SVP38 ...
• Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair

  Giel Korsten, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-lamin A/C (Santa Cruz, ref. sc-7292, lot. L1919), anti-lamin B1 (Abcam ...
• Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically and functionally segregated regions

  Eric Casey, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-C-FOS (1:500, Santa Cruz Biotechnology, SC-52), rabbit anti-dsRed (1:500 ...
• DePARylation is critical for S phase progression and cell survival

  Litong Nie, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Antibodies against C-terminus of PARG were purchased from Santa Cruz Biotechnology (SC-398563 ...
• Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus

  Jacob H. Wilmot, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-c-Fos goat primary antibody (1:5000, SC52, Santa Cruz), anti-GFP chicken primary antibody (1:300 ...
• Biochemical properties of chromatin domains define genome compartmentalization

  Federica Lucini, et al., bioRxiv - Genomics 2024

  Quote: ... anti-Lamin A/C (Santa Cruz sc-6215, goat 1:1000) and anti-Lamin B (Santa Cruz sc-6216 ...
• SYNERGISTIC ANTITUMOR EFFECT OF NAPROXEN AND SORAFENIB IN HEPATOCELLULAR CARCINOMA

  Etkin Akar, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cytochrome-c (Santa Cruz Biotechnology, cat. no: sc-7159, 1:100), mTOR (Cell Signaling Technology ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-c-Myc (9E10) (1:1,000, sc-40, Santa Cruz biotechnology) anti-Tubulin (1:10,000 ...
• The functional specificity of CDC42 isoforms is caused by their distinct subcellular localization

  Yamini Ravichandran, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit polyclonal anti-PKCζ C-20 (Santa Cruz Biotech SC-216), mouse anti-EEA1(BD biosciences 610457 ...
• Dentate Neurogenesis Modulates Dorsal Hippocampal Excitation/Inhibition Balance Crucial for Cognitive Flexibility

  Haowei Li, et al., bioRxiv - Neuroscience 2023

  Quote: ... c-Fos: rabbit and goat polyclonal IgG (1:200, Santa Cruz Biotechnology ...
• Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length

  Maciej Kliszczak, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-human Lamin A/C (sc-376248, Santa Cruz Biotechnology) at 1:1000 (IB and IF) ...
• ABIN1 is a negative regulator of effector functions in cytotoxic T cells

  Sarka Janusova, et al., bioRxiv - Immunology 2023

  Quote: ... anti-NF-κB p65 (clone C-20, Santa Cruz #sc-372), anti-IκB AF 488 (clone L35A5 ...
• S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition

  Lauren R. Begg, et al., bioRxiv - Cancer Biology 2023

  Quote: ... human S100A8 (clone C-10, Santa Cruz Biotechnology, sc-48352 HRP), mouse S100A8 (R&D Systems ...
• Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling

  Yvonne Baumer, et al., bioRxiv - Immunology 2023

  Quote: ... and galectin-8-AF790 (clone C-8, Santa Cruz Biotechnologies, USA)
• Phosphorylation of MYCN and MAX by PAK family kinases is a novel tumor-suppressor mechanism in neuroblastoma with potential therapeutic implications

  Esteban J Rozen, Kim Wigglesworth, Jason Shohet, bioRxiv - Cancer Biology 2023

  Quote: ... c-MYC (sc-40) and MAX (sc-8011) from Santa Cruz Biotechnology ...
• Helicobacter pylori cancer associated CagA protein drives intestinal metaplastic transition in human gastric organoids

  Mar Reines, et al., bioRxiv - Cell Biology 2023

  Quote: ... C-terminal CagA bk-20 (Santa Cruz Cat. No. sc-48128), p-Tyr (Santa Cruz Cat ...
• Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis

  Yosuke Sakamachi, et al., bioRxiv - Immunology 2024

  Quote: ... and mouse anti-SP-C (Santa Cruz, Dallas, TX; 1:100). Secondary antibodies (Donkey anti-mouse Alexa Fluor 594 ...
• Phosphatases control the duration and range of cAMP/PKA microdomains

  Filippo Conca, et al., bioRxiv - Cell Biology 2024

  Quote: Anti-PKA Catα (C-20) (sc-903; Santa Cruz Biotechnologies, USA), anti-PKA Reg Iα/β (G-6 ...
• Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity

  Irene Schwartz, et al., bioRxiv - Cell Biology 2024

  Quote: ... Lamin A/C Antibody (E-1) (Santa Cruz Biotechnology, 1:1000), Monoclonal Anti-Vinculin antibody (Sigma-Aldrich ...
• GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade

  Madison F. Walker, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse anti-GRK2 (C-9) was from Santa Cruz (sc-13143). Alexa 555 anti-rat was obtained from Thermo-Fisher Scientific (A21434) ...
• ZW sex chromosome structure in Amborella trichopoda

  Sarah B. Carey, et al., bioRxiv - Genomics 2024

  Quote: Hi-C Illumina reads from Amborella trichopoda (var. Santa Cruz 75), were separately aligned to the HAP1 and HAP2 contig sets with Juicer 73 ...
• DET1 dynamics underlie co-operative ubiquitination by CRL4^DET1-COP1 complexes

  Abigail E Burgess, et al., bioRxiv - Biochemistry 2024

  Quote: ... mouse α-COP1 (1:1000, Santa Cruz, C-terminal epitope, sc166799) and/or mouse Anti-α -tubulin (clone DM1A ...
• TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi

  Joshua Carlson, et al., bioRxiv - Microbiology 2024

  Quote: ... Mouse anti-c-Myc monoclonal antibody (9E10) was from Santa Cruz Biotechnology (Dallas ...
• AMH regulates ovary size by counteracting ovarian follicle cluster effects

  Carmen Lim, et al., bioRxiv - Physiology 2024

  Quote: ... 0.05 μg/mL goat anti-AMH (MIS C-20, Santa Cruz Biotechnology ...
• Gestational arsenite exposure alters maternal postpartum heart size and induces Ca²⁺ handling dysregulation in cardiomyocytes

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... Mybp-c (1:1000, Rabbit Ab, Santa Cruz Technologies, sc-137180), and α-Actin (1:1000 ...
• SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation

  Katsutoshi Taguchi, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit polyclonal antibody C-20 (1:2000; Santa Cruz Biotechnology) was used.
• Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multi-site polarity substrate Lgl

  Christopher P. Earl, et al., bioRxiv - Biochemistry 2024

  Quote: ... The rabbit anti-aPKCzeta (1:500, c-20, Santa Cruz Biotechnology) was used as primary antibody.
• Correlation of mitochondrial TOM core complex stop-and-go and open-closed channel dynamics

  Shuo Wang, et al., bioRxiv - Biophysics 2021

  Quote: ... Aqueous droplets (∼200 nl) containing 7 μM Fluo-8 sodium salt with a maximum excitation wavelength of 495 nm (Santa Cruz Biotechnology, USA), 400 μM EDTA ...
• KDM5C is a sex-biased brake against germline gene expression programs in somatic lineages

  Katherine M. Bonefas, et al., bioRxiv - Molecular Biology 2024

  Quote: ... transferred overnight onto a fluorescent membrane, blotted for rabbit anti-KDM5C (in house, 1:500) and mouse anti-DAXX (Santa Cruz #(H-7): sc-8043 ...
• Growth Signaling Autonomy in Circulating Tumor Cells Aids Metastatic Seeding

  Saptarshi Sinha, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and immunoblotting was carried out for GIV with the mouse monoclonal antibody H-6 (Santa Cruz Biotechnology) as described previously(70) ...
• ODF2 negatively regulates CP110 levels at centrioles/basal bodies to control biogenesis of primary cilia

  Madeline Otto, Sigrid Hoyer-Fender, bioRxiv - Cell Biology 2023

  Quote: ... Samples were incubated with the primary antibodies anti-acetylated α-tubulin (clone 6-11B-1; Santa Cruz Biotechnology ...
• Apicosome: newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells

  Xiaofen Li, et al., bioRxiv - Neuroscience 2022

  Quote: ... The cultures prepared from P0 WT mice were treated with 5 µM DAPT (CAS208255-80-5; Santa Cruz Biotechnology, Dallas, TX, USA) or 0.05% (v/v ...
• Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules

  Pierre-Michaël Coly, et al., bioRxiv - Cell Biology 2023

  Quote: ... the aortas were blocked with 5 % BSA for 20 min and stained with anti-Cadherin-5 antibody (Santa Cruz biotechnology, sc-6458) and DAPI ...
• A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

  Marek M. Drozdz, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and cytochrome C (2CYTC-199; Santa Cruz, #sc-81752; dilution 1:50). Secondary antibodies used were donkey anti-mouse and donkey anti-rabbit conjugated to Alexa Fluor 488 or Alexa Fluor 647 (Thermo ...