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101 - 150 of 8668 citations for 6 Methyl 5 4 phenyl 1 3 thiazol 2 yl 2 trifluoromethyl nicotinic acid since 2020

• Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts

  Pei Ying Ng, et al., bioRxiv - Cell Biology 2022

  Quote: ... pERK1/2 (Santa Cruz sc-7383, 1/500 dilution), t-ERK1/2 (Promega V114A ...
• Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

  Rachel Ulferts, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-ATP6V1B1/2 (sc55544, Santa Cruz, WB 1:1000), anti-FLAG (F1804 ...
• Identification of SSX2IP/Msd1 as a Wtip-binding partner by targeted proximity biotinylation

  Bo Xiang, et al., bioRxiv - Biochemistry 2021

  Quote: ... GFP (1:1000, B-2, Santa Cruz, mouse monoclonal), Biotin (1:10000 ...
• PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 controls the transport of E-cadherin

  Giovanna Grimaldi, et al., bioRxiv - Cell Biology 2020

  Quote: ... tankyrase-1/2-rabbit polyclonal antibody (Santa Cruz Biotechnology) was used at 1:1000 for western blotting ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti Erk1/2 (1:5000; Santa Cruz Biotechnology), rabbit anti-TrkB (1:1000 ...
• Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine β-hydroxylase deficient mice

  Darshana Kapri, et al., bioRxiv - Neuroscience 2022

  Quote: ... 2) goat DCX (1:250; Santa Cruz Biotechnology, USA); 3 ...
• CDK4/6 inhibition and dsRNA sensor agonism co-operate to enhance anti-cancer effects through ER stress and immune modulation of tumour cells

  Victoria Roulstone, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PARP-1 (F-2) (sc-8007, Santa Cruz Biotechnology), anti-DNMT (ab92314 ...
• Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease

  Zsuzsanna Lichner, et al., bioRxiv - Cell Biology 2024

  Quote: ... Polycystin 2 (1:500, sc-28331, Santa Cruz Biotechnology), MRTF-A (1:1000 ...
• Dynamic mRNA stability changes buffer transcriptional activation during neuronal differentiation and are regulated by RNA binding proteins

  Yuan Zhou, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MAP-2 (Santa Cruz, Cat# Sc-5359, 1:50), β-tubulin-III (Cell signaling ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... EF-2 (Santa Cruz Biotechnology, SC-166415, 1:5000) and B-TUB (Proteintech ...
• Chemical inhibition of prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming

  Ratnakar Tiwari, et al., bioRxiv - Molecular Biology 2022

  Quote: ... methyl aspartate (Santa Cruz) and nicotinamide riboside (Cayman ...
• Hypothalamic estrogen receptor alpha mediates key side effects of tamoxifen therapy in mice

  Z Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Sections were then blocked for 1 h in 10% BSA and 2% normal goat serum (NGS) and incubated overnight at 4 °C with primary antibody (ERα, 1:250, sc-8002, Santa Cruz). Following 3 × 10 min washing in PBS ...
• Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma

  Katharine J. Herbert, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Coverslips were blocked with 2% goat serum before overnight incubation with primary antibody at 4°C [anti-Rad51 (1:500, Santa Cruz), anti-53BP1 (1:1000 ...
• miR-126 modulates neural progenitor cell development

  Jeroen Bastiaans, et al., bioRxiv - Cell Biology 2024

  Quote: ... NPC were infected at 80% confluency by adding virus stocks at a final dilution of 1:2 together with 4 µg/mL Polybrene (Santa Cruz), followed by spinning down of virus onto the NPC at 2300 rpm for 1 hour at 30°C ...
• A GRAB sensor reveals activity-dependent non-vesicular somatodendritic adenosine release

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2020

  Quote: ... S-(4-nitrobenzyl)-6-thioinosine (NBTI, Santa Cruz), dipyridamole (Santa Cruz) ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... The membrane was incubated with the following primary antibodies in TBST + 5% BSA at 4°C overnight: rabbit polyclonal anti-MEK-3 (1:500, Santa Cruz Biotechnology, #sc-961), rabbit polyclonal anti-p38 (1:1000 ...
• ETV7 reduces inflammatory responses in breast cancer cells by repressing TNFR1/NF-κB axis

  Erna Marija Meškytė, et al., bioRxiv - Cancer Biology 2022

  Quote: ... which was probed over-night at 4°C with specific antibodies diluted in 1-3% skimmed milk-PBS-0.1% Tween solution: TNFR1 (H-5, Santa Cruz Biotechnologies, DBA, Milan, Italy), STAT3 (124H6 ...
• The Wolfram-like variant WFS1^E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice

  Simone Patergnani, et al., bioRxiv - Neuroscience 2023

  Quote: ... cells were reconstituted for 2 hours with 5 µM coelenterazine wt (Santa Cruz Biotechnology) in DMEM high glucose supplemented of 0.1% FBS and transferred to the perfusion chamber ...
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5 mg of lysate was incubated with Parkin antibody (2 μg; Santa Cruz 32282) or with Calcineurin antibody (2 μg ...
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... Tankyrase-1/2 (H-350) (Santa Cruz Biotechnology; sc-8337; 1:50), Tankyrase-1/2 (E10 ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... Rabbit),pRSK-1/2 (1/1000 dilution, #sc-12898-R, Santa Cruz, Rabbit), SF3B1 / SAP 155 (B-3 ...
• CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia-induced invasion, and therapeutic resistance

  Jan C. Lumibao, et al., bioRxiv - Cancer Biology 2022

  Quote: ... GPx-1/2 (1:100, sc-133160, Santa Cruz Biotechnology, Dallas, TX), GPx-4 (1:100 ...
• Ankylosis homologue mediates cellular efflux of ATP, not pyrophosphate

  Flora Szeri, et al., bioRxiv - Biochemistry 2021

  Quote: ... and using α-tubulin as a loading control (mouse anti-α-tubulin B-5-1-2, Santa Cruz Biotechnology, Dallas, TX).
• DNA density is a better indicator of a nuclear bleb than lamin B loss

  Samantha Bunner, et al., bioRxiv - Cell Biology 2024

  Quote: ... Cells were incubated overnight at 4◦C or for 1 h at RT in 2%BSA PBS containing primary antibody mouse anti-lamin B1 (Santa Cruz, sc-365214, 1/500). Cells were washed using PBS and incubated for 1 h at room temperature with secondary antibody in 2% BSA PBS ...
• Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair

  Kristel Martinez Lagunas, et al., bioRxiv - Cell Biology 2022

  Quote: ... the sections were stained for the following antibodies (diluted in 0.2% (v/v) Triton X-100 in Animal Free Blocker and Diluent) overnight at 4°C: CC10 (1:50, Santa Cruz-sc365992), α-smooth muscle actin-Cy3 conjugated (1:50 ...
• Inorganic Pyrophosphate Promotes Osteoclastogenic Commitment and Survival of Bone Marrow Derived Monocytes mediated by Egr-1 up-regulation and MITF phosphorylation

  Samir M. Abdelmagid, et al., bioRxiv - Cell Biology 2020

  Quote: ... Rabbit anti-mouse phospho-ERK 1/2 (Thr202, Tyr204) (Cat# sc-136521) and ERK 1/2 (Cat# sc-292838) were purchased from Santa Cruz (Santa Cruz, CA). Anti-mouse phospho-MITF-S307 was gift from Dr Michael Ostrowski (Ohio State University ...
• CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

  Dalia Hassan, Jichao Chen, bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-NK homeobox 2-1 (NKX2-1, 1:1000, sc-13040, Santa Cruz), rabbit anti-pro-surfactant protein C (SFTPC ...
• Whole transcriptome profiling of placental pathobiology in SARS-CoV-2 pregnancies identifies placental dysfunction signatures

  Nataly Stylianou, et al., bioRxiv - Developmental Biology 2023

  Quote: ... followed by fluorescent staining with Pan-Cytokeratin (PanCK, clone AE-1/AE-3, AF488, Santa Cruz NBP2-33200AF488, [2 µg/mL], CA, USA) to identify trophoblasts ...
• Protein kinase Cε activation induces EHD-dependent degradation and downregulation of K_ATP channels: Implications for glucose stimulated insulin secretion

  Christopher J Cockcroft, et al., bioRxiv - Cell Biology 2020

  Quote: ... or mouse anti-Rme-1-4 (Santa Cruz Biotechnology, EHD (E-5), 0.8 μg/ml ...
• Dormant replication origin firing links replication stress to whole chromosomal instability in human cancer

  Ann-Kathrin Schmidt, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following antibodies were used in the indicated dilutions: anti-α-tubulin (1:1000, B-5-1-2, Santa Cruz, USA, cat no sc-23948), anti-β-actin (1:10000 ...
• Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations

  Teresa Cunha-Oliveira, et al., bioRxiv - Cell Biology 2022

  Quote: ... SOD-2 (1:1000, sc-133134, RRID: AB_2191814, Santa Cruz), SOD1 (1:2000 ...
• The “Proxitome” of Arabidopsis Processing Bodies Reveals a Condensate-Membrane Interface Instructing Actin-Driven Directional Growth

  Chen Liu, et al., bioRxiv - Cell Biology 2022

  Quote: ... rat anti-tubulin YL1/2 (1:200; Santa Cruz Biotechnology), mouse anti-DCP1 (diluted 1:100 ...
• Human-specific progenitor sub-domain contributes to extended neurogenesis and increased motor neuron production

  Sumin Jang, Elias Gunmit, Hynek Wichterle, bioRxiv - Developmental Biology 2022

  Quote: ... FOXP1 (Mouse, 1:400 Santa Cruz A-2 sc-398811), NKX2-2 (Mouse ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-TSG101 (1:200, C-2, Santa Cruz Biotechnology), mouse anti-ALIX (1:500 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-TSG101 (dilution 1/200; Santa Cruz Biotechnology; C-2), anti-CD81 (dilution 1/500 ...
• Control of telomere length in yeast by SUMOylated PCNA and the Elg1 PCNA unloader

  Pragyan Singh, Inbal Gazy, Martin Kupiec, bioRxiv - Molecular Biology 2023

  Quote: ... 2 μl of (HA, Santa Cruz Biotechnology (sc7392; 1:1,000) or MYC ...
• In vitro reconstitution reveals requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

  Susanne Hellmuth, Olaf Stemmann, bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-Rad21 (1:800; B-2, Santa Cruz Biotechnology), rabbit anti-Rad21 (1:1,000 ...
• Thermo-optoplasmonic single-molecule sensing on optical microcavities

  Nikita A. Toropov, et al., bioRxiv - Biophysics 2023

  Quote: ... 2 µL of 1 µM tryptamine (Santa Cruz SC-206065) was added to the chamber in order to observe steps in the Δλ of the WGM.
• Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

  Christina Plattner, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-mucin 2 (Santa Cruz Biotechnology, #sc-515032, 1:500), anti-EpCAM (R&D ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... MRCKβ (A-2) (1:100; Santa Cruz Biotechnology sc-390127), Tubulin (1:200 ...
• Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors

  Sameer Farouk Sait, et al., bioRxiv - Cancer Biology 2022

  Quote: ... with ERK-2 (sc-1647; Santa Cruz Biotechnology; 1:1000) used as a loading control.
• Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes

  Mateusz S. Wietecha, et al., bioRxiv - Genomics 2022

  Quote: ... 2) mouse anti-periostin (1:100; Santa Cruz; #sc-398631) and rabbit anti-MFAP4 (1:100 ...
• Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution

  Toufic Kassouf, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-PARP-1 (F-2) (#sc-8007, Santa Cruz), mouse anti-TIA-1 (G-3 ...
• Phase transitions of a SEC14-like condensate at Arabidopsis plasma membranes regulate root growth

  Chen Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat α-tubulin YL1/2 (1:200; Santa Cruz Biotechnology), mouse α-FLAG (1:250) ...
• IL8 Drives an Elaborate Signal Transduction Process for CD38 to Produce NAADP from NAAD and NADP⁺ in Endolysosomes to Effect Cell Migration

  Tae-Sik Nam, et al., bioRxiv - Cell Biology 2020

  Quote: ... containing 5 % nonfat dry milk for 2 h at room temperature and then incubated with anti-NaK-ATPase (1:2500; Santa Cruz Biotechnology), anti-LAMP-1 (1:2500 ...
• Effective NGN2-based neuronal programming of hiPSCs in an automated microfluidic platform

  S Angiolillo, S Micheli, O Gagliano, bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-OCT4-3/4 (C-10) (1:200, sc-5279 Santa Cruz Biotechnology) and mouse anti-TUBULIN β 3 (βIIITUBB ...
• Role of canonical and non-canonical cAMP Sources in CRHR2α-dependent Signaling

  Natalia G. Armando, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The following antibodies were used: anti–phospho-ERK1/2 (E-4, sc-7383) from Santa Cruz Biotechnology ...
• An Enhancer Trap system to track developmental dynamics in Marchantia polymorpha

  Alan O. Marron, et al., bioRxiv - Plant Biology 2023

  Quote: ... Auxin synthesis inhibitor treatments were done by growing gemmae on plates made with 10µM 5-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol (yucasin) (ChemCruz, Santa Cruz Biotechnology) or 100µM L-kynurenine (Sigma ...
• SRF is a non-histone methylation target of KDM2B and SET7 in the regulation of myogenesis

  Hosouk Joung, et al., bioRxiv - Developmental Biology 2020

  Quote: ... About 1∼2 mg total lysate was incubated with 2 μg antibody or IgG (Santa Cruz Biotechnology, Santa Cruz, CA, USA) coupled to protein A/G agarose beads (Santa Cruz Biotechnology ...
• SRF is a non-histone methylation target of KDM2B and SET7 in the regulation of myogenesis

  Hosouk Joung, et al., bioRxiv - Developmental Biology 2020

  Quote: ... About 1∼2 mg total lysate was incubated with 2 μg antibody or IgG (Santa Cruz Biotechnology, Santa Cruz, CA, USA) coupled to protein A/G agarose beads (Santa Cruz Biotechnology ...