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1251 - 1300 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Flotillin-2 regulates EGFR activation, degradation, and cancer growth

  David J. Wisniewski, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-FLOT2 (B-6) antibody was obtained from Santa Cruz biotechnology and used for immunoprecipitation ...
• Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

  Delphine M. Lees, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The anti-HSC70 (Santa Cruz, clone B-6, sc-7298) or GAPDH (Millipore ...
• SHP2 Inhibition Abrogates Adaptive Resistance to KRAS^G12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

  Carmine Fedele, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Rabbit polyclonal antibodies against SHP2 (sc-280; 1:1000) and mouse monoclonal ERK-2 (D2: sc-1647; 1:1000) were purchased from Santa Cruz Biotechnology ...
• ADAMDEC1 maintains a novel growth factor signaling loop in cancer stem cells

  James S Hale, et al., bioRxiv - Cancer Biology 2019

  Quote: ... 1×105 cells were pre-incubated for 1-2 h in N2 medium without antibiotics and 1 μg/μl of polybrene (Santa Cruz) to increase transduction efficiency ...
• PCNA recruits cohesin loader Scc2/NIPBL to ensure sister chromatid cohesion

  Ivan Psakhye, et al., bioRxiv - Cell Biology 2022

  Quote: ... Mouse monoclonal anti-HA (1:2000; clone F-7) and anti-PCNA (1:2000; clone F-2) antibodies were from Santa Cruz Biotechnology ...
• Myelination deficits in the auditory brainstem of a mouse model of Fragile X Syndrome, a possible mechanism for auditory phenotypes

  Alexandra Lucas, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse Sox-10 (A-2) (Santa Cruz, Dallas, TX, USA; sc-365692, 1:500) diluted in blocking solution with 1% NGS and incubated overnight (Table 1) ...
• Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection

  Ruobing Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-MUC5B antibody (mouse monoclonal, Santa Cruz Biotechnology, 1:500 cat#SC-39395-2). The anti-SARS-CoV nucleoprotein (N ...
• Leveraging co-evolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms

  Simon Snoeck, et al., bioRxiv - Biochemistry 2024

  Quote: ... prior to incubation with α-GFP (B-2) HRP (Santa Cruz 9996 HRP, 1:1500). Western blots were imaged with a Bio-Rad ChemiDoc and Image Lab Touch Software (v2.2.0.08) ...
• Modeling Mechanical Activation of Macrophages During Pulmonary Fibrogenesis for Targeted Anti-Fibrosis Therapy

  Ying Xu, et al., bioRxiv - Bioengineering 2023

  Quote: ... and Rho associated coiled-coil containing protein kinase 2 (Santa Cruz, sc-398519, 1:100). These antibodies were labeled with fluorophore-conjugated ...
• Suppressive effects of oroxylin A on intracellular proliferation of Toxoplasma gondii via host cell ERK phosphorylation inhibition

  Ziyue Z Zhang, et al., bioRxiv - Microbiology 2024

  Quote: ... The following primary antibodies used were mouse monoclonal antibody ERK 1/2 (1:1,000 dilution, sc-514302; Santa Cruz Biotechnology, Inc., CA), mouse monoclonal antibody p-ERK 1/2 (1:1,000 dilution ...
• Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes

  Nadine Nagy, et al., bioRxiv - Immunology 2023

  Quote: ... Membranes were blocked with TBS containing 1 % casein and 2 % BSA followed by incubation with primary antibodies (survivin 1:2000, 71G4B7, Cell Signaling; beta actin 1:5000 sc-4778, Santa Cruz Biotechnology ...
• HIV-1 RNA genomes initiate host protein packaging in the cytosol independently of Gag capsid proteins

  Jordan T. Becker, et al., bioRxiv - Cell Biology 2020

  Quote: ... or glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was detected using a mouse monoclonal antibody (6C5, 1:2500 dilution, Santa Cruz Biotechnology) and anti-rabbit or anti-mouse secondary secondary antibodies conjugated to an infrared fluorophore (IRDye800CW ...
• Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

  Loganathan Palanikumar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... This was followed by incubation for 3 h at room temperature with horseradish peroxidase-conjugated mouse IgG antibody (1:10,000; Santa Cruz). Finally ...
• Oxytocin has sex-specific effects on social behaviour and hypothalamic oxytocin immunoreactive cells but not hippocampal neurogenesis in adult rats

  Paula Duarte-Guterman, et al., bioRxiv - Neuroscience 2020

  Quote: ... Tissue was incubated in a goat anti-DCX polyclonal antibody (1:1000 in PBS containing 3% normal rabbit serum and 0.4% Triton X-100; Santa Cruz Biotechnology ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: The following antibodies were used in this study: Rabbit polyclonal anti-MEK-3 (1:500, Santa Cruz Biotechnology, #sc-961), rabbit polyclonal anti-p38 (1:1000 ...
• Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate

  Xiaowen Duan, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibodies detecting TRARG1 (sc-292062 or sc-377025) and 14-3-3 (sc-1657) were from Santa Cruz Biotechnology ...
• YAP nuclear translocation through dynein and acetylated microtubule controls fibroblast activation

  Eunae You, et al., bioRxiv - Cell Biology 2019

  Quote: ... Smad2/3 (Santa Cruz Biotech., #sc-133098) and dynein (Millipore ...
• Essential role of Bone morphogenetic protein 15 in porcine ovarian and follicular development and ovulation

  Yufeng Qin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and p-Smad2/3 (Santa cruz, sc11769) were diluted 1:50 in PBS.
• Multiview super-resolution microscopy

  Yicong Wu, et al., bioRxiv - Bioengineering 2021

  Quote: ... sodium acrylate (Santa Cruz, 7446-81-3), N ...
• Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS

  Anatoly Urisman, et al., bioRxiv - Cancer Biology 2019

  Quote: ... 0.2 % Zwittergent 3-16 (Santa Cruz Biotechnology), and 50 mM Tris-HCl ...
• Dicer1 is reduced in APPswe/PSEN1dE9 mice and is regulated by Nrf2

  Yan Wang, Meiling Lian, Jing Zhou, Shengzhou Wu, bioRxiv - Neuroscience 2019

  Quote: ... caspase 3 (Santa Cruz Biotechnology, Santa Cruz, CA ...
• Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR⁺ breast tumors

  Tzu-Yu Feng, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-PDGF-B (F-3, Santa Cruz), anti-GAPDH antibody (6C5 ...
• Phosphatidylinositol 4-kinase III beta regulates cell shape, migration and Focal Adhesion number

  Patricia Bilodeau, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5’-ATAAGCTCCCTGCCCGAGTC-3’ (Santa Cruz sc-430739).
• T606-phosphorylation deprives the function of Kaiso as a transcription and oncogenic factor

  Wei Tian, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 14-3-3σ (sc-100638, Santa Cruz), Ser/Thr/Tyr phosphor-protein (ab15556 ...
• The selective autophagy receptor p62 and the heat shock protein HSP27 facilitate lysophagy via the formation of phase-separated condensates

  Elizabeth R. Gallagher, Erika L.F. Holzbaur, bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-Galectin-3 (Santa Cruz Biotech ...
• Desmin intermediate filaments and tubulin detyrosination stabilize growing microtubules in the cardiomyocyte

  Alexander K. Salomon, et al., bioRxiv - Cell Biology 2022

  Quote: ... clone F-3 (Santa Cruz sc-28325); immunofluorescence ...
• Pharmacological modulation of the cytosolic oscillator affects glioblastoma cell biology

  Paula M Wagner, Mario E Guido, bioRxiv - Cancer Biology 2023

  Quote: ... CHIR99021 (GSK-3 Inhibitor XVI, Santa Cruz), or KL001 (Cryptochrome protein stabilizer ...
• Intermediary role of lung alveolar type 1 cells in epithelial repair upon Sendai virus infection

  Belinda J Hernandez, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-sex determining region Y-box 2 (SOX2, 1:250, Santa Cruz Biotechnology, SC-17320), rat anti-antigen identified by monoclonal antibody Ki 67 (Ki67 ...
• Actin-based myosin XXI (13) molecular motor is involved in early phase of Leishmania cytokinesis

  Rani Bajaj, Chhitar M. Gupta, bioRxiv - Cell Biology 2021

  Quote: ... α-tubulin mouse monoclonal antibody (B-5-1-2; Cat.No.23948) was purchased from Santa Cruz Biotechnology company ...
• Rab40/Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration and invasion

  Erik S Linklater, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-HA (WB 1:500, IP 2 μg/1mg cell lysate, Santa Cruz SC F-7), Alexa-Fluor-568–phalloidin (IF 1:1000 ...
• Prorenin from renal tubules is a major driver of diabetic kidney disease

  Anna Federlein, et al., bioRxiv - Physiology 2022

  Quote: ... polyclonal goat anti-aquaporin-2 (dilution 1:200) (sc-9882, Santa Cruz Biotechnology, Santa Cruz, CA) monoclonal mouse anti-calbindin (dilution 1:500 ...
• Prorenin from renal tubules is a major driver of diabetic kidney disease

  Anna Federlein, et al., bioRxiv - Physiology 2022

  Quote: ... polyclonal goat anti-aquaporin-2 (dilution 1:200) (sc-9882, Santa Cruz Biotechnology, Santa Cruz, CA) monoclonal mouse anti-calbindin (dilution 1:500 ...
• OMA1 protease eliminates arrested protein import intermediates upon depolarization of the inner mitochondrial membrane

  Magda Krakowczyk, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The antibodies were appropriately diluted in PBS with 2% BSA 1:50 for TOMM20 (Santa Cruz) and 1:1000 for calnexin (Abcam) ...
• Molecular mechanism of dynein-dynactin activation by JIP3 and LIS1

  Kashish Singh, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse monoclonal anti-Dynein IC1/2 (Cat no. sc-13524, Santa Cruz Biotechnology, 1:1000 dilution), Mouse monoclonal anti-GAPDH (Cat no ...
• A root-specific NLR network confers resistance to plant parasitic nematodes

  Daniel Lüdke, et al., bioRxiv - Plant Biology 2023

  Quote: ... Mouse monoclonal anti-GFP antibody conjugated to HRP (B-2, Santa Cruz Biotech; 1:5000 dilution) or mouse monoclonal anti-mCherry TrueMAB antibody conjugated to HRP (OTI10G6 ...
• Subcellular localization of glypican-5 associates with dynamic cell motility and cell communication of the human mesenchymal stem cell line U3DT

  Masao Takeuchi, et al., bioRxiv - Cell Biology 2019

  Quote: ... Anti-Rab 11A antibody (A-6: sc-166912, Santa Cruz Biotech), Anti-acetyl-alpha-tubulin antibody (D20G3 ...
• The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis

  Luisa Capalbo, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-MYPT1 (clone C-6, Santa Cruz, sc-514261), (Abcam ...
• The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis

  Luisa Capalbo, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-PP1β (clone A-6, Santa Cruz, sc-365678), mouse monoclonal anti-PP1γ (clone A-4 ...
• SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

  Scott B. Biering, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-TACE/ADAM17 (Santa Cruz Biotechnologies, B-6, sc-390859), mouse anti-Cathepsin L (Thermo Fisher Scientific ...
• The Vitamin D Receptor (VDR) Regulates Mitochondrial Function in C2C12 Myoblasts

  Stephen P. Ashcroft, et al., bioRxiv - Physiology 2019

  Quote: ... vitamin D receptor (D-6) (VDR; 13133) was from Santa Cruz Biotechnology ...
• The nucleolar aberrancies that drive ribosome impairment induced by RNA binding proteins are hallmarks of aging

  Pedro Aguilar-Garrido, et al., bioRxiv - Molecular Biology 2023

  Quote: The primary antibodies used were hnRNP K (Santa Cruz, D-6), p53 (Santa Cruz ...
• Microglia undergo rapid phenotypic transformation in acute brain slices but remain essential for neuronal synchrony

  Péter Berki, et al., bioRxiv - Neuroscience 2023

  Quote: ... sections were blocked in TBST containing 6% BlottoA (Santa Cruz Biotechnology), 10% normal goat serum (NGS ...
• Infection-induced vascular inflammation in COVID-19 links focal microglial dysfunction with neuropathologies through IL-1/IL-6-related systemic inflammatory states

  Rebeka Fekete, et al., bioRxiv - Immunology 2023

  Quote: ... sections were blocked in TBST containing 6% BlottoA (Santa Cruz Biotechnology), 10% normal goat serum (NGS ...
• A novel mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteoclastogenic effects of breast cancer cells

  Vatsal Kumar, et al., bioRxiv - Bioengineering 2023

  Quote: ... samples were incubated with goat polyclonal IL-6 antibody (Santa Cruz) (1:100 ...
• Circular RNAs arising from synaptic host genes are modulated by SFPQ RNA-binding protein and increased during human neuronal differentiation

  Michelle Watts, et al., bioRxiv - Neuroscience 2023

  Quote: ... or 6 μg normal mouse αIgG (Santa Cruz sc-2025, RRID:AB_737182). To each immunoprecipitation ...
• Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland

  Pierre Gillotay, et al., bioRxiv - Developmental Biology 2020

  Quote: ... at 1:200, anti-monomeric Kusabira-Orange 2 (rabbit, MBL amalgam PM051M) at 1:250 and anti-p63 (mouse, Santa Cruz Biotechnology 4A4) at 1:200 ...
• High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

  Tsutomu Shinohara, et al., bioRxiv - Cell Biology 2024

  Quote: ... 0.2% Triton X-100 in 1XTBS) for 1 h at RT followed by incubation with primary antibodies against ERG (Santa Cruz, 1:100) for 72 h and EC marker ...
• Amphipathic helices of cellular proteins can replace the helix in M2 of Influenza A virus with only small effects on virus replication

  Bodan Hu, et al., bioRxiv - Cell Biology 2019

  Quote: ... blocked (3% BSA in PBS for 1h) and incubated with primary anti-M2 mAb14C2 (1:300 in PBS supplemented with 3% BSA, Santa Cruz) for 1h and then with anti-mouse secondary antibody coupled to Alexa Fluor 488 (1:1000 ...
• IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington’s disease mouse model

  Rana Soylu-Kucharz, Ali Khoshnan, Åsa Petersén, bioRxiv - Neuroscience 2021

  Quote: ... the sections were left in the respective primary antibody solutions in 3% appropriate corresponding serum in TBS-T (anti-huntingtin (sc-8767; 1:500; goat; Santa Cruz), anti-ubiquitin (1:2000 ...
• Assessing Functional Androgen Receptor Pathway Activity in Response to Radiotherapy Using hK2-targeted PET Imaging

  Claire M Storey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Sections were blocked in 10% normal goat serum in PBS for 30 minutes before staining with an anti-AR (N-20) antibody (1 µg/mL, 3 h; Santa Cruz, #SC-816 ...