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1151 - 1200 of 7988 citations for 3 Methyl 1 6 naphthyridine 2 carboximidamide hydrochloride since 2020

• Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears

  Tian Wang, et al., bioRxiv - Cell Biology 2022

  Quote: ... SOX2 (1:200-500, R&D and 1:400 Santa Cruz Biotechnology), POU4F3 (1:400 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... Myosin ID (1:500; H-1; sc-515292; Santa Cruz Biotechnology, Inc); GAPDH (1:50000 ...
• Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells

  Riccardo Ballarò, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rat anti-mouse LYVE-1 1:50 (Santa Cruz Biotechnology, sc-65647), rabbit anti-mouse Albumin 1:100 (Proteintech ...
• A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

  Izumi Sasaki, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Caspase-1 p10 (sc-514; 1/1000 dilution, Santa Cruz Biotechnology), anti-GSDMD (ab209845 ...
• Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

  Sanjana Rajan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... monocarboxylate transporter 4 (Santa Cruz Biotechnology, [D-1] sc-376140, 1:50) and vimentin (Cell Signaling Technology ...
• Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

  Swagata Konwar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and mouse anti human TSP-1 (1:100, Santa Cruz sc-59887) followed by donkey anti mouse Alexa 488 (1:500 ...
• WNT/β-catenin dependant alteration of cortical neurogenesis in a human stem cell model of SETBP1 disorder

  Lucia F. Cardo, Meng Li, bioRxiv - Developmental Biology 2021

  Quote: ... 1/200 (Santa Cruz), Mouse anti-TRA1-60 and Mouse anti-TRA1-81 1/200 (both Millipore) ...
• WNT/β-catenin dependant alteration of cortical neurogenesis in a human stem cell model of SETBP1 disorder

  Lucia F. Cardo, Meng Li, bioRxiv - Developmental Biology 2021

  Quote: ... 1/500 (Santa Cruz), Goat anti-SOX2 ...
• Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at ER monitoring and regulating fatty acids

  Song-iee Han, et al., bioRxiv - Molecular Biology 2021

  Quote: ... SREBP-1 (Santa Cruz Biotechnology ...
• Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

  Andrea Serra-Marques, et al., bioRxiv - Cell Biology 2020

  Quote: ... KLC-1 (Santa Cruz Biotechnology ...
• SMARCA4 supports the oncogenic landscape of KRAS-driven lung tumors

  Shivani Malik, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TTF-1 (Santa Cruz), overnight at 4°C in a humidified chamber ...
• Tle4 controls both developmental acquisition and postnatal maintenance of corticothalamic projection neuron identity

  Maria J. Galazo, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1:200 (Santa Cruz Biotechnology Cat# sc-9125 ...
• ARID1A regulates R-loop associated DNA replication stress

  Shuhe Tsai, et al., bioRxiv - Cell Biology 2020

  Quote: ... (1:250) (Santa Cruz), BAF155 (1:1000 ...
• Lytic Reactivation of the Kaposi’s sarcoma-associated herpesvirus (KSHV) is Accompanied by Major Nucleolar Alterations

  Nofar Atari, et al., bioRxiv - Microbiology 2020

  Quote: ... PICT-1 (Santa Cruz), PML (Santa Cruz) ...
• γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release

  Madeleine D. Hu, et al., bioRxiv - Immunology 2021

  Quote: ... ZO-1 (Santa Cruz) and/or GFP (Abcam) ...
• Extracellular vesicles induce aggressive lung cancer via non-canonical integrin-EGFR-KRAS signaling

  Karla Rubio, et al., bioRxiv - Cancer Biology 2022

  Quote: ... NKX2-1 (Santa Cruz), EZH2 (Abcam) ...
• Ozanimod Attenuates Human Cerebrovascular Endothelial Derived MMP-9 Activity and Preserves Barrier Properties Following In Vitro Acute Ischemic Injury

  Trevor S. Wendt, Rayna J. Gonzales, bioRxiv - Physiology 2023

  Quote: ... VCAM-1 (Santa Cruz Biotechnology ...
• Epigenetics and chromatin structure regulate var2csa expression and the placental binding phenotype in Plasmodium falciparum

  Todd Lenz, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1% paraformaldehyde (Santa Cruz) in PBS for 1 h ...
• Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia

  Jan Zlamal, et al., bioRxiv - Immunology 2022

  Quote: ... 75 μL of wPLTs were pretreated with the Fc-gamma-RIIA blocking monoclonal antibody (moAb) anti-CD32 (moAb IV.3; Stemcell™ technologies, Vancouver, Canada) or a monoclonal isotype control (clone SC-2025; Santa Cruz Biotechnology, Dallas, USA) for 30 min at RT prior to HIT IgG treatment ...
• Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia

  Judith Cossins, et al., bioRxiv - Neuroscience 2024

  Quote: Nitrocellulose was incubated in blocking buffer (PBS containing 3% powdered skimmed milk) for 30 minutes at rt and then incubated with primary mouse anti-DOK7 antibody (Santa Cruz cat no sc-390856) diluted 1:250 in blocking buffer for 1 hour at rt with gentle agitation ...
• A Conserved Requirement for RME-8/DNAJC13 in Neuronal Autolysosome Reformation

  Sierra Swords, et al., bioRxiv - Cell Biology 2023

  Quote: Neurobasal medium) every 3 days. Neurons were co-transfected with Control shRNA (Cat. sc108060) or DnaJC13 (RME-8) shRNA (Santa Cruz, Cat. sc-77968-SH) with GFP-LC3 ...
• Alternative splicing in neuroblastoma generates RNA-fusion transcripts and is associated with vulnerability to spliceosome inhibitors

  Yao Shi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Following primary antibodies were used: BAG2(sc-390262, 1:200), phospho-ser396-Tau(sc-101815, 1:1000), HSC70(sc-7298, 1:200) from Santa Cruz; phosphor-ser404-Tau(44-758G ...
• In vivo-mimicking 3D cultures secrete distinct extracellular vesicles upon cancer cell invasion

  Jens C. Luoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-APOA1 (sc-376818, 1:100), anti-ITGB4 (sc-514426, 1:300) and anti-VCL (sc-73614, 1:500) was bought from Santa Cruz Biotechnology.
• Circumventing drug treatment? Polyethylenimine functionalized nanoparticles inherently and selectively kill patient-derived glioblastoma stem cells

  Neeraj Prabhakar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and incubated with a primary antibody PARP-1 (sc-7150, 1:1000) and P62 (sc-28359, 1:500 dilution) from Santa Cruz Biotechnology ...
• The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2

  Ana Domingo-Muelas, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1:800 rat anti-BrdU, Abcam ab6326; 1:400 chicken anti-DCX, Abcam ab153668; 1:300 goat anti-DCX, Santa Cruz sc-8066 ...
• Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues

  Joel Pinczewski, et al., bioRxiv - Pathology 2020

  Quote: Working concentrations of antibodies to βcat (1:500, Epitomics, Burlingame, CA # 1247-1) and phospho-βcat (pS33-βcat 1:200, Santa Cruz, Santa Cruz ...
• Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon navigation

  Hiroki Takechi, et al., bioRxiv - Neuroscience 2020

  Quote: ... rat antibody to CadN (Ex#8, 1:50, DSHB), mouse antibody to Repo (8D12, 1:20, DSHB) mouse antibody to myc (4E10, 1:100, Santa Cruz), rabbit antibody to RFP (1:500 ROCKLAND) ...
• The Splicing Factor XAB2 interacts with ERCC1-XPF and XPG for RNA-loop processing during mammalian development

  Evi Goulielmaki, et al., bioRxiv - Genetics 2020

  Quote: ... 1:50), XPA (wb: 1:500), XPF (F-11, wb: 1:500) and XPG (sc12558, wb: 1:200) were from Santa Cruz Biotechnology ...
• Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders

  Pallavi M. Gosavi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... MOLM-13 and K562 cells were transduced by spinfection at 1,800 × g for 1.5 h at 37 °C with 5 μg ml-1 and 1 μg ml-1 polybrene (Santa Cruz Biotechnology), respectively ...
• Isoform-specific Disruption of the TP73 Gene Reveals a Critical Role for TAp73gamma in Tumorigenesis via Leptin

  Xiangmudong Kong, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-p21 (sc-53870, 1:3000), anti-p130 (sc-374521, 1:3000) and anti-PML (sc-377390, 1:3000) were purchased from Santa Cruz Biotechnology ...
• Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB

  Zhicheng Cui, et al., bioRxiv - Cell Biology 2022

  Quote: ... antibodies to GAPDH (6C5) (Cat# sc-32233 - 1:15000 WB) and LAMP-1 (H4A3) (Cat# sc-20011 - 1:500 IF) were from Santa Cruz; antibody to HA.11 Epitope Tag (Cat# 901513 ...
• α-syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson’s disease

  A Anandhan, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-GPx4 (1:1000, sc-166570), anti-AKR1C1 (1:1000, sc-398596), and anti-GCLM (1:1000, sc-166603) were from Santa Cruz Biotechnology (Dallas ...
• Site-Specific Knockdown of Microglia in the Locus Coeruleus Regulates Hypervigilant Responses to Social Stress in Female Rats

  Brittany S. Pate, et al., bioRxiv - Neuroscience 2022

  Quote: ... PVDF membranes incubated overnight at 4°C with the following primary antibodies diluted in 1:1 Blok/0.1M PBS + 0.2% Tween-20 : mouse anti-GAPDH (1:1000, Santa Cruz, Santa Cruz, CA), rabbit anti-CX3CL1 (1:1000 ...
• Haloperidol-induced immediate early genes in striatopallidal neurons requires the converging action of cAMP/PKA/DARPP-32 and mTOR pathways

  Oriane Onimus, et al., bioRxiv - Neuroscience 2022

  Quote: ... Antibodies for cFos (1:400, #sc-52), Arc (1:400, #sc-17839), and Zif268 (1:400, #sc-189) were purchased from Santa Cruz Biotechnology [29] ...
• The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells

  Chengfang Pan, et al., bioRxiv - Physiology 2024

  Quote: ... Cells were then incubated in primary antibody solution (primary antibody (anti-EP1: 1:200, Ab217925, Abcam, UK; anti-EP2: 1:200, Ab167171, Abcam; anti-EP3: 1:200, Sc-57105, Santa Cruz Biotechnology ...
• Ex vivo tissue perturbations coupled to single cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis

  Niklas J. Lang, et al., bioRxiv - Cell Biology 2023

  Quote: ... 10% normal donkey serum or 1% BSA were used for blocking nonspecific binding and primary antibodies were incubated (VWA1 1:100, Proteintech, 14322-1-AP; CLDN5 1:100, Santa Cruz, sc-374221 ...
• A potent agonist-based PROTAC targeting Pregnane X Receptor that delays colon cancer relapse

  Lucile Bansard, et al., bioRxiv - Cancer Biology 2024

  Quote: ... final dilution: 1/500), Ubiquitin (sc-166553, final dilution: 1/500) and PXR (sc-48340, final dilution: 1/500) from Santa Cruz, GSPT1 (ab126090 ...
• Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

  Peng Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: Antibody against HAND1 (sc-390376) (WB: 1:1000, IF for embryos: 1:100, IF for cells: 1:200) was purchased from Santa Cruz. Antibody against FOXF1 (Abclonal ...
• Annexin A2 and lamin B join membrane recycling compartments for the assembly of biomolecular condensates operating in mitotic partitioning

  Ann Kari Grindheim, et al., bioRxiv - Cell Biology 2024

  Quote: ... while the mouse monoclonal antibody against LAMP-1 (H5G11; 1:200 dilution) and rabbit polyclonal antibody against Rab7 (R4779; 1:50 dilution) were purchased from Santa Cruz Biotechnology and Sigma ...
• G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

  Yi-Hong Li, et al., bioRxiv - Immunology 2024

  Quote: ... followed by incubation at 4◦C overnight with primary antibodies diluted in the blocking buffer (rabbit anti-Dclk1 1:1000, Abcam, ab31704; rabbit anti-Dclk1-488 1:1000, Abcam, ab202754; rabbit anti-Gnat3 1:500, Santa Cruz Biotechnology ...
• Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviors in mice

  Bin Hu, et al., bioRxiv - Neuroscience 2024

  Quote: Rabbit polyclonal anti-ErbB4 antibody (sc-283, 1:2000, or 1:1000 for blotting, 1:100 for staining) was purchased from Santa Cruz, mouse monoclonal anti-PV antibody (P3088 ...
• SS-31 protects against bleomycin-induced lung injury and fibrosis

  Quankuan Gu, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... the membrane was subjected to blocking with 5% skim milk powder for an additional 1 to 2h prior to incubation with the designated antibodies: ZO-1 (1:1000 dilution, Santa Cruz), E-cadherin (1:1000 dilution ...
• BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

  Shan Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... 25% of total crude virus extracted was used to infect U87MG for 2 days before G418 (Santa Cruz) selection at 1.2mg/mL.
• Molecular mechanism for kinesin-1 direct membrane recognition

  Zuriñe Antón, et al., bioRxiv - Cell Biology 2021

  Quote: ... Non-targeting control siRNA was obtained from Horizon Discovery and human KLC1/2 siRNAs were from Santa Cruz Biotechnology ...
• Asciminib mitigates DNA damage stress signalling induced by cyclophosphamide in the ovary

  Luca Mattiello, et al., bioRxiv - Cell Biology 2020

  Quote: Antibodies for Msy-2 (sc-21316) and p-AKT (T308) (sc-16646-R) were purchased from Santa Cruz; antibody for p-H2AX (γH2AX ...
• Oncogenic protein condensates suppress growth factor perception and modulate drug tolerance

  David Gonzalez-Martinez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cleared cell lysates were incubated for 2 hours with Protein A/G agarose beads (Santa Cruz, SC-2003) that were hybridized with EGFR antibody (Thermo ...
• Biomechanical dependence of SARS-CoV-2 infections

  Alexandra Paul, et al., bioRxiv - Bioengineering 2022

  Quote: ... and incubated with 4 μg/ml Anit-ACE-2 conjugated to Alexa 647 (Santa Cruz Biotechnology, SC-390851) at 4°C overnight ...
• Mesenchymal stem cells support human vascular endothelial cells to form vascular sprouts in human platelet lysate-based matrices

  Eva Rossmanith, et al., bioRxiv - Bioengineering 2022

  Quote: ... To stain focal adhesions a mouse mAb to paxillin (2 μg clone B2, Santa Cruz Biotechnology, Dallas, TX) followed by goat-anti-mouse Fab fragments labeled with AF® 488 (3 μg/ml ...
• CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS mutant cancers

  Srikanta Basu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Mouse antibody to β-Actin (sc-47778) and p-ERK1/2 (sc-136521) were obtained from Santa Cruz Biotechnology ...
• The anti-tubercular activity of simvastatin is mediated by cholesterol-dependent regulation of autophagy via the AMPK-mTORC1-TFEB axis

  Natalie Bruiners, et al., bioRxiv - Immunology 2020

  Quote: ... A total of 2 × 106 macrophages were lysed in 100μL RIPA lysis buffer (Santa Cruz Biotechnology, Dallas, TX). Subcellular Protein Fractionation Kit for Cultured Cells (Thermo Fischer Scientific ...