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1051 - 1100 of 7898 citations for 1 2 Chloropyridin 3 yl 3 3 dimethylazetidin 2 one since 2020

• Establishment of Bovine Trophoblast Stem Cells

  Yinjuan Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-PL-1(Santa Cruz, sc-376436; 1:200) and anti-PTGS2 (Sigma ...
• LOX-1 and MMP-9 inhibition attenuates the detrimental effects of delayed rt-PA therapy and improves outcomes after acute ischemic stroke

  Kajsa Arkelius, et al., bioRxiv - Neuroscience 2023

  Quote: ... VCAM-1 (1:500 #sc-13160 Santa Cruz Biotechnology), diluted in 5% bovine serum albumin (BSA ...
• BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss

  Mario A. Shields, et al., bioRxiv - Pathology 2023

  Quote: ... Zo-1 (Santa Cruz Biotech #sc-33725, 1:200), Amylase (Santa Cruz Biotech #sc-46657 ...
• Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans

  Junran Yan, et al., bioRxiv - Genetics 2024

  Quote: ... 1 mM IPTG (Santa Cruz CAS 367-93-1), and 12.5 μg/ml tetracycline (BioBasic TB0504 ...
• CRISPR-mediated correction of skeletal muscle Ca²⁺ handling in a novel DMD patient-derived pluripotent stem cell model

  Cristina Morera, et al., bioRxiv - Cell Biology 2022

  Quote: ... Tra-1-60 (Santa Cruz, sc-21705; 1:100), SSEA4 (BD Bioscience ...
• p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners

  Anamari Brdar, et al., bioRxiv - Biophysics 2024

  Quote: ... anti-p53 (DO-1, Santa Cruz Biotechnologies, 1:1000), anti-Vinculin (clone 7F9 ...
• Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

  Swagata Konwar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and TSP-1 (1:100, Santa Cruz sc-59887) for immunofluorescence imaging.
• Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement

  Haneen S. Alsehli, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-SOX17 (R&D, 1:50) were diluted and YAP 1 (Santa Cruz, 1:50) were diluted in the blocking buffer and incubated for 48 h in the dark at 4°C on a shaker ...
• Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

  Man Zhu, et al., bioRxiv - Biochemistry 2024

  Quote: ... Poly (ADP-ribose) polymerase-1 (PARP-1, 1:1000; Catalog# sc-8007; SANTA CRUZ BIOTECHNOLOGY, INC.), TFEB (1:3000 ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... followed by incubation overnight with primary antibodies (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) at 4 degree or for 1hr at 37 °C ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... for 10 min at RT and then stained with a primary antibody (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) for 12 h at 4 °C ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-fibromodulin (1:500, 1% casein, sc-33772, Santa Cruz), anti-pSer2448-mTOR (1:1000 ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... anti-human Caspase-1 (Santa Cruz, sc515, 1: 1,000 dilution), anti-human GSGMD (sigma ...
• RhoA- and Ran-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

  Benoit Dehapiot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Rock-1 (1/100, Goat polyclonal; Santa Cruz sc-6056). Secondary antibodies were Alexa Fluor 488-conjugated donkey anti-goat ...
• CDK5 influences the organization of the Circadian Machinery in peripheral clocks

  Jürgen Ripperger, Urs Albrecht, Andrea Brenna, bioRxiv - Molecular Biology 2021

  Quote: ... while Tubulin by Abcam (1:1000) and Lamin B by Santa Cruz (1:1000). The day after ...
• GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

  Ari W. Schaler, et al., bioRxiv - Neuroscience 2020

  Quote: ... CamKIIα (1:2000, A-1, sc13141) was from Santa Cruz Biotechnology ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

  Joana Sá-Pessoa, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-Cullin-1 (1:200, Santa Cruz Biotechnology sc-12761), anti-Flag M2 (1 μg ...
• Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

  Robin M. Delaine-Smith, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GLI-1 Antibody (C-1, sc-515751) from Santa Cruz Biotechnology.
• Reliance of neuronal gene expression on cohesin scales with chromatin loop length

  Lesly Calderon, et al., bioRxiv - Genomics 2022

  Quote: ... CUX-1 (1:400; rabbit polyclonal sc-13024, Santa Cruz) and anti phospho-histone H3 (Ser10 ...
• The phospho-regulated amphiphysin/endophilin interaction is required for synaptic vesicle endocytosis

  Christiana Kontaxi, Michael A. Cousin, bioRxiv - Neuroscience 2023

  Quote: ... goat syndapin 1 (1:1000; Santa Cruz Biotechnology, sc-10412), and mouse PSD95 (1:1000 ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-Zo-1 (1:200, Santa Cruz, sc-33725), mouse anti-MDR1 (1:50 ...
• Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

  James L. Daly, et al., bioRxiv - Neuroscience 2022

  Quote: ... VPS29 (Santa Cruz; D-1; sc-398874; 1:500 WB), VPS35 (Abcam ...
• Vitamin C is an efficient natural product for prevention of SARS-CoV-2 infection by targeting ACE2 in both cell and in vivo mouse models

  Yibo Zuo, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Ubiquitin (Ub) (Santa Cruz, 12987-1-AP, 1:1000), anti-K48 Ub (Cell Signaling Technology ...
• A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons

  Monika Moissidis, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-PGC-1⍺ (1:200, Santa Cruz #sc-518025), mouse anti-Kv1.1 (1:1,000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... TIA-1 (1:200; goat, Santa Cruz Biotechnology, sc-1751); TIAR (1:1000 ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ARMC8 (E-1, sc-365307; Santa Cruz Biotechnology, 1:500), WDR26 (ab85962 ...
• The large GTPase Guanylate-Binding Protein-1 (GBP-1) promotes mitochondrial fission in glioblastoma

  Ryan C. Kalb, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti-GBP-1 (1b1) (1:25; Calbiochem or Santa Cruz), anti-myc (1:50 ...
• A comprehensive genetic catalog of human double-strand break repair

  Ernesto López de Alba, et al., bioRxiv - Molecular Biology 2024

  Quote: ... PCNA (1:1000, TBST 1% BSA, Santa Cruz sc-56).
• Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis

  C. Llaó-Cid, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-Numb 1 1:1000 (sc-136554, Santa Cruz), rabbit anti-β-catenin 1:2000 (8480 ...
• GlycoRNA-L and glycoRNA-S mediate human monocyte adhesion via binding to Siglec-5

  Mingui Fu, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-VCAM-1 polyclonal antibody (Santa Cruz, 1:1000), rabbit polyclonal anti-β-actin (Santa Cruz ...
• Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation

  Carlos Antón-Plágaro, et al., bioRxiv - Cell Biology 2024

  Quote: ... VPS29 (Santa Cruz; D-1; sc-398874; 1:500 WB), VPS35 (Abcam ...
• High Sucrose Diets Contribute to Brain Angiopathy with Impaired Glucose Uptake, and Psychosis-related Higher Brain Dysfunctions in Mice

  Shinobu Hirai, et al., bioRxiv - Neuroscience 2021

  Quote: ... PV-235; 1:1000), rabbit anti-glucose transporter 1 (Glut1, Frontier Institute, Af1020; 1:1000) and mouse anti-tubulin (Santa Cruz, sc-32293; 1:10000). After washing three times with TBST ...
• Melanoma Addiction to GCDH is Mediated by NRF2 Tumor Suppressor Function

  Sachin Verma, et al., bioRxiv - Cancer Biology 2021

  Quote: ... (dilution 1:1,000) Mcl-1 Antibody (22) (dilution, 1: 1,000) and HSP90 (F-8) (dilution, 1: 5,000) from Santa Cruz Biotechnology ...
• Pre-rRNA spatial distribution and functional organization of the nucleolus

  Yu-Hang Pan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Primary antibodies were diluted with 1% BSA (FBL, Abcam, 1:300 dilution; RPA194, Santa Cruz, 1:50 dilution) and incubate for 1 hour at RT ...
• Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

  Amy Tarangelo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... human p53 (Cat #SC-126, DO-1, Santa Cruz, 1:1000), p21 C’-terminus (Cat# 2947 ...
• Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

  Stefanie Koster, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse-anti-p53 (DO-1) (1:500, Santa Cruz, # sc-126), mouse-anti-Chlamydia Hsp60 (A57-E4 ...
• Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

  Yulia Steblyanko, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-PRC1 (C-1) (1:500; Santa Cruz, sc-3769839), mouse anti-NDC80/HEC1 (1:2000 ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-LOX (1:500, 1% casein, sc-32409, Santa Cruz). Anti-rabbit IgG HRP (NA934V ...
• Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation

  Stine Kjær Morthorst, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-PALS-1 (Santa Cruz, cat#sc-365411; 1:50), goat anti-MYC (Abcam ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Importin β-1 (Santa Cruz sc-11367, 1:50), goat anti-Lamin B (Santa Cruz sc-6217 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Importin β-1 (Santa Cruz sc-1863, 1:50), mouse anti-Importin β-1 (Santa Cruz sc-137016 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Importin β-1 (Santa Cruz sc-137016, 1:50), rabbit anti-Importin β-1 (Santa Cruz sc-11367 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Importin β-1 (Santa Cruz sc-1863, 1:50), mouse anti-Importin β-1 (Santa Cruz sc-137016 ...
• CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

  Lisa Crozier, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse anti-p53 (DO-1) (Santa Cruz, sc-126; 1/1000), rabbit anti-actin (Sigma ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-VCAM-1 (1:200 dilution, sc-13160, Santa Cruz), goat anti-VE-cadherin (1:300 dilution ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-Ku86 (Santa Cruz, B-1, sc-5280; 1:500), mouse anti-α-tubulin (Millipore ...
• Extended longevity geometrically-inverted proximal tubule organoids for protein uptake studies

  Eric Parigoris, et al., bioRxiv - Bioengineering 2022

  Quote: ... mouse anti-aquaporin-1 (Santa Cruz #sc-32737, 1:200 dilution), mouse anti-ezrin/villin-2 (BD #610602 ...
• Pharmacological tuning of microRNAs in FAP-derived Extracellular Vesicles by HDAC inhibitors promotes regeneration and reduces fibrosis in dystrophic muscles

  M. Sandonà, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Flotillin-1 (1/200, H-104, Santa Cruz Biotechnology), mouse anti-Alix (3A9 ...