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951 - 1000 of 7763 citations for 5 Nitro 1H benzo de isoquinoline 1 3 2H dione since 2020

• The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons

  Swati Mishra, et al., bioRxiv - Cell Biology 2022

  Quote: ... Lysosome associated membrane protein-1 (LAMP1) at 1:250 (#sc 2011; Santa Cruz); Tropomyosin receptor kinase B (TRKB ...
• Extracellular Vesicles Analysis in the COVID-19 Era: Insights on Serum Inactivation Protocols Towards Downstream Isolation and Analysis

  Roberto Frigerio, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-TSG101 (1:1000, Novus Bio) and anti-Apo1 (1:1000, Santa Cruz). After washing with T-TBS ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... –TUBB3 (1:300; Covance, MRB-435P) -Vimentin (1:100; Santa Cruz, sc-373717). Secondary antibodies used were ...
• Translational profiling of mouse dopaminoceptive neurons reveals a role of PGE2 in dorsal striatum

  Enrica Montalban, et al., bioRxiv - Neuroscience 2020

  Quote: ... Vehicle (DMSO in PBS, 1/1) or misoprostol (Santa Cruz Biotechnology, #SC-201264), were infused at a dose of 50 μg.kg−1.day−1 ...
• A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

  Lei Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-SATB2 (Millipore, ABE600, 1:2,000; Santa Cruz Biotechnology, sc-81376, 1:50), anti-TBR1 (Millipore ...
• Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function

  Manish Kumar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 53BP1 (1:200, CST) or anti-BRCA1 primary antibody (1:500, Santa Cruz) overnight at 4°C ...
• Specificity of Gβ and γ subunits to the SNARE complex both at rest and after α_2a adrenergic receptor stimulation

  Yun Young Yim, et al., bioRxiv - Biochemistry 2021

  Quote: ... and rabbit anti-Gβ (Santa Cruz, sc-378, 1:10,000 and 1:5000) were used ...
• Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells

  Ying Wang, et al., bioRxiv - Cell Biology 2020

  Quote: The antibodies used for immunohistochemistry included DMP-1 (1:100 dilution, Santa Cruz), DSPP (1:100 dilution ...
• Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells

  Ying Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... the primary antibodies were as follows: DMP-1 (1:200 dilution, Santa Cruz) and DSPP (1:200 dilution ...
• Retinoic acid treatment recruits macrophages and increases axonal regeneration after optic nerve injury in the frog Rana pipiens

  Valeria De La Rosa-Reyes, et al., bioRxiv - Neuroscience 2021

  Quote: ... which were anti-Arginase 1 (1:50; catalog # sc-271430; Santa Cruz Biotechnology), anti-CD68 (ED1 ...
• PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins

  Ying Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... or Western blotting: anti-PSGL-1 (Santa Cruz Biotech, sc-13535, 1:200), anti-cofilin (Cell Signaling ...
• NCLX controls hepatic mitochondrial Ca²⁺ extrusion and couples hormone-mediated mitochondrial Ca²⁺ oscillations with gluconeogenesis

  Mahmoud Taha, et al., bioRxiv - Physiology 2024

  Quote: ... for 1 h or an anti-mouse (1:5000, sc-2005, Santa Cruz) solution for 1 h ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Myosin ID (1:500; H-1; sc-515292; Santa Cruz Biotechnology, Inc). For fluorescence intensity measurements ...
• Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

  Seda Yasa, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Lamp1 (WB: 1:1000, IF: 1:100, Santa Cruz Biotech sc-19992), anti-Lamp2a (WB ...
• Synergistic induction of blood-brain barrier properties

  Gergő Porkoláb, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit anti-PECAM-1 (Santa Cruz, cat# sc-1506-R, AB_831096, 1:200), rabbit anti-β-catenin (Sigma-Aldrich ...
• Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators

  Ingrid M. Saldana-Guerrero, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MASH1 (ASCL1) (Abcam, Ab211327, 1:100 or Santa Cruz, SC-374104, 1:500); Ki67 (Abcam ...
• Actin nucleators safeguard replication forks by limiting nascent strand degradation

  Jadwiga Nieminuszczy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DIAPH1 (Bethyl, A300-077A-T, 1:1000; Santa Cruz, sc-373807, 1:500), CHK1 – phospho S345 (Cell Signalling ...
• Chlamydial protease-like activating factor targets SLC7A11 for degradation to induce ferroptosis and facilitate dissemination

  Wentao Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... fibroblast-specific protein 1 (FSP1; 1:500, Santa Cruz Biotechnology Cat# sc-377120), TfR1(1:500 ...
• The Parkinson’s Disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

  Katy R. McCarron, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-ALIX (1:1,000 WB, 1:500 IF, Santa Cruz Biotechnology; sc-53540), anti-Cathepsin D (1:2,000 WB ...
• Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder

  Min Jee Kwon, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:250 Mouse anti-Sp4 antibody (B-1, Santa Cruz Biotechnology, sc-390124) followed by 1:25,000 anti-mouse antibody (Thermo Fisher Scientific ...
• A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice

  Susan E. Maloney, et al., bioRxiv - Animal Behavior and Cognition 2024

  Quote: ... and 1:500 mouse anti-AVP (1:500, Santa Cruz Biotech, sc-9888). Slices incubated in primary antibodies overnight at 4C on a horizontal mixer ...
• Effects of gypenosides on enteroendocrine L-cell function and GLP-1 secretion

  Chinmai Patibandla, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... cells were fixed with 4% paraformaldehyde for 10 mins at 4°C followed by 30mins blocking with 2% BSA and stained with anti-GLP-1 antibody (1:200) (Gt pAb to GLP-1, SC-26637, Santa Cruz Biotechnology) overnight in a humid chamber at 4°C ...
• Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome

  Rahul S. Samant, et al., bioRxiv - Biochemistry 2022

  Quote: ... Antibodies for HSP90α/β (sc-7947, 1:500), CDC37 (sc-5617, 1:500), and AHA1 (sc-50527, 1:500) were from Santa Cruz Biotechnology ...
• Long-term dynamic changes of NMDA receptors following an excitotoxic challenge

  Alberto Granzotto, et al., bioRxiv - Neuroscience 2022

  Quote: ... Cells were incubated for 1 h at RT with anti-GluN1 antibody (1:200, Alomone) and anti-NOS1 antibody (1:50, Santa Cruz Biotechnology) in the blocking solution ...
• Peripheral neuropathy linked mRNA export factor GANP reshapes gene regulation in human motor neurons

  Rosa Woldegebriel, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit α-GAPDH 1:1000 (#14C10, Cell Signalling) with secondary 1:5000 (#111-035-144, Jackson) and mouse α-NEFL 1:1000 (#sc39073, Santa Cruz) with secondary 1:5000 (#115-035-146 ...
• High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells

  Kayleigh Slater, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and probed with primary antibodies (CysLT1 : Abcam [ab151484], 1:1000, CysLT2 : Cayman Chemical [CAY120560] 1:1000, Alpha-Tubulin : Santa Cruz, 1:200). Secondary antibodies were anti-mouse IgG HRP-linked (Cell Signalling [7076S] 1:1000) ...
• Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues

  Joel Pinczewski, et al., bioRxiv - Pathology 2020

  Quote: Working concentrations of antibodies to βcat (1:500, Epitomics, Burlingame, CA # 1247-1) and phospho-βcat (pS33-βcat 1:200, Santa Cruz, Santa Cruz, CA # SC-16743-R ...
• Site-Specific Knockdown of Microglia in the Locus Coeruleus Regulates Hypervigilant Responses to Social Stress in Female Rats

  Brittany S. Pate, et al., bioRxiv - Neuroscience 2022

  Quote: ... PVDF membranes incubated overnight at 4°C with the following primary antibodies diluted in 1:1 Blok/0.1M PBS + 0.2% Tween-20 : mouse anti-GAPDH (1:1000, Santa Cruz, Santa Cruz, CA), rabbit anti-CX3CL1 (1:1000 ...
• IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency

  Marco Flores-Mendez, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000; CD68, Bio Rad MCA1957, 1:250; NEUN, Millipore MAB377, 1:2000; GFAP, Aves Lab 75-240, 1:1000, S6, Santa Cruz sc74459 ...
• Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner

  Masaya Harada, et al., bioRxiv - Neuroscience 2024

  Quote: ... before staining with the respective primary antibodies (NAc and LH with αGFP chicken 1:1000, Aves Labs ref GFP-1010; αmCherry rabbit, 1:1000, abcam ab167453; and αOrexin goat, 1:500, Santa Cruz Biotech ...
• Analysis of the Distal Urinary Tract in Larval and Adult Zebrafish Reveals Unrecognized Homology to the Human System

  Ibrahim Jubber, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... sc-15179 (Goat polyclonal) at 1:400 dilution for zebrafish tissue and 1:100-1:400 dilution for human tissue (Santa Cruz Biotechnology), Cytokeratin 5/6 (mouse monoclonal ...
• Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes in R6/2 mice

  Danielle A. Simmons, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-OCT3/4 (sc-5279, 1:200), anti-SOX2 (sc-365823, 1:200), anti-NANOG (sc-293121, 1:200) (all from Santa Cruz Biotechnology), anti-PAX6 (DSHB ...
• Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathways

  Xianping Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and rabbit anti-HA (CST, 1:200), rabbit anti-Flag (CST, 1:200) and mouse anti- Su(H) (Santa Cruz, 1:100), mouse anti-NICD (DSHB ...
• A pseudotyped lentivirus-based assay to titer SARS-CoV-2 neutralizing antibodies in Mexico

  José Antonio Cruz-Cardenas, et al., bioRxiv - Microbiology 2022

  Quote: ... Briefly 3 x105 cells were incubated on ice with mouse anti-human ACE2 monoclonal antibody conjugated to AF-647 (Santa Cruz Biotechnology, USA, cat. SC-390851) following manufacturer’s instructions ...
• ZNF143 binds DNA and stimulates transcription initiation to activate and repress direct target genes

  Jinhong Dong, et al., bioRxiv - Genomics 2024

  Quote: ... was aliquoted into each of 3 tubes with antibody (2µg anti-HA Invitrogen #26183, 8µg anti-SP1 Santa Cruz Biotechnology sc-17824 X, or mock IP) and incubated with end-over-end rotation at 4°C overnight ...
• Proteome biology of primary colorectal carcinoma and corresponding liver metastases

  Matthias Fahrner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cells were incubated for 48 h after adding 5 mM (final conc.) of N-methyl-DL-aspartic acid (MDLA) (Santa Cruz), solved in water ...
• Astrocytic striatal GABA transporter activity governs dopamine release and shows maladaptive downregulation in early parkinsonism

  Bradley M. Roberts, et al., bioRxiv - Neuroscience 2020

  Quote: ... DL-2-Amino-5-phosphonovaleric acid (AP5, 50 μM), disulfiram (10 μM) and SKF-89976A hydrochloride (SKF, 20 μM) were obtained from Santa Cruz Biotechnology ...
• The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

  Samuel Rivero-Hinojosa, et al., bioRxiv - Genomics 2021

  Quote: ... an equimolar mix of CTCF C-terminus commercial antibody were used (anti-CTCF B-5(sc-271514) and C-20 (sc-15914)) from Santa Cruz; anti-CTCF (D31H2 ...
• Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

  S. Jordan Kerns, et al., bioRxiv - Cancer Biology 2021

  Quote: ... All single-cell samples were distributed at 5×105 cells/mL for live staining with mouse anti-human CEA IgG (Santa Cruz) in DPBS with 2% FBS (Sigma) ...
• A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

  Lindsay B Alcaraz, et al., bioRxiv - Cancer Biology 2021

  Quote: ... sc-10725), and the mouse monoclonal anti-human cath-D (clone C-5, sc-377124) antibodies were purchased from Santa Cruz Biotechnology ...
• Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma

  Hui Si Kwok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Pfeiffer and Karpas-422 were transduced by spinfection at 1,070 x g (5 acceleration, 2 brake) for 90 min at 37 °C with 8 µg/ml polybrene (Santa Cruz Biotechnology). After 48 h post-transduction ...
• Transcriptional changes in Plasmodium falciparum upon conditional knock down of mitochondrial ribosomal proteins RSM22 and L23

  Swati Dass, et al., bioRxiv - Microbiology 2022

  Quote: ... The membrane was blocked with 5% milk/PBS for 2 h before incubation with mouse monoclonal anti-HA antibody (Sc-7392, Santa Cruz) at 1:10,000 for overnight at 4°C ...
• p27 regulates the autophagy-lysosomal pathway via the control of Ragulator and mTOR activity in amino acid deprived cells

  Ada Nowosad, et al., bioRxiv - Cell Biology 2020

  Quote: ... The following antibodies were used in PLA assays: mouse anti p27 (SX53G8.5, sc-53871), LAMP1 (E-5, Sc-17768), rabbit anti p27 (C19, sc-528) (Santa Cruz Biotechnology), rabbit anti LAMTOR1 (#8975) ...
• Thalamo-hippocampal pathway regulates incidental memory load in mice

  G. Torromino, et al., bioRxiv - Neuroscience 2022

  Quote: ... FG labelled cells were visualized on 40 µm coronal slices counterstained with a 5 μg/ml propidium iodide (Santa Cruz Biotechnology) staining solution in PBS 1x for 10 min ...
• Mitosis without DNA replication in mammalian somatic cells

  Olivier Ganier, et al., bioRxiv - Molecular Biology 2020

  Quote: ... permeabilized in 0.5% Triton X-100 for 5 min and processed for indirect immunofluorescence: anti-cyclin B1 (Santa Cruz, sc-245), anti MPM2 (Millipore ...
• Inhibition of lysyl oxidase-like 2 ameliorates folic acid-induced renal tubulointerstitial fibrosis

  Sung-Eun Choi, et al., bioRxiv - Pathology 2020

  Quote: ... HK-2 cells were treated with media containing 5 μg/ml of polybrene (cat. no. sc-134220; Santa Cruz Biotechnology, Inc.), and then LOXL2 shRNA lentiviral particles and control shRNA lentiviral particles of 1 and 2 multiplicity of infection (MOI ...
• The mitochondrial Cu⁺ transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro

  Cat McCann, et al., bioRxiv - Cell Biology 2022

  Quote: ... sc-365090), anti-sarco/endoplasmic reticulum Ca2+-ATPase (SERCA, sc-271669), anti-COX2 Antibody (D-5, sc-514489) were from Santa Cruz Biotechnologies (Dallas ...
• Inhibitory input directs astrocyte morphogenesis through glial GABA_BR

  Yi-Ting Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3mg of nuclear lysates were used for IP with 2 μg IgG or 5 μg primary antibodies (normal mouse IgG, Santa Cruz Biotechnology ...
• Reconstituted depolarization-induced Ca²⁺ release platform for skeletal muscle disease mutation validation and drug discovery

  Takashi Murayama, et al., bioRxiv - Physiology 2022

  Quote: ... The cells were blocked with 5% BSA/PBS for 30 min and incubated overnight with primary antibodies against Cav1.1 (sc-514685, Santa Cruz Biotechnology), β1a (MA5-27714 ...
• EPIGENETIC MODULATION VIA THE C-TERMINAL TAIL OF H2A.Z

  László Imre, et al., bioRxiv - Cell Biology 2023

  Quote: After salt or intercalator treatment the samples were incubated with 500 μl 5% (m/v) Blotto Non-Fat Dry Milk (Santa Cruz Biotechnology Inc. ...