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801 - 850 of 7904 citations for 5 Chloro 1 vinyl 2 pyridone since 2020

• Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics

  Thomas De Luca, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-GM130 (clone B-10, 2 μg/mL, cat. no. sc-55591, Santa Cruz Biotechnology), anti α-actinin (clone H-2 ...
• Astrocytes express DMT1 and transferrin receptors, which transport iron thus activating Ca²⁺ signalling: possible role in neuroprotection against iron overload?

  Maosheng Xia, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Na+/K+-ATPase alpha1/2 antibody and the secondary antibodies were bought from Santa Cruz Biotechnology (Santa Cruz ...
• VHL ligand binding increases intracellular level of VHL

  Julianty Frost, Sonia Rocha, Alessio Ciulli, bioRxiv - Biochemistry 2021

  Quote: ... Protein lysates were incubated with 2 μg of HIF-1α antibody (Santa Cruz; sc-53546) or 2 μg of mouse IgG control antibody (Sigma ...
• Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury

  Ayşe N. Ozantürk, et al., bioRxiv - Immunology 2022

  Quote: ... Cells were blocked by adding 2% bovine serum albumin (9048-46-8, Santa Cruz Biotechnology) in PBS for 30 min at RT followed by washing twice with PBS ...
• Werner syndrome protein (WRN) regulates cell proliferation and the human papillomavirus 16 life cycle during epithelial differentiation

  Claire D. James, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Fluorescent in situ hybridization (FISH ...
• Early detection of SARS-CoV-2 in circulating immune cells in a mouse model

  Tingting Geng, et al., bioRxiv - Microbiology 2021

  Quote: ... hACE2 (Mouse-anti-Human ACE-2, Cat# sc-390851, clone E-11, Santa Cruz Biotechnology) indirectly labeled with goat-anti-mouse Alexa Fluor 594 ...
• Regulation of DNA damage response by trimeric G-protein Signaling

  Amer Ali Abd El-Hafeez, et al., bioRxiv - Cancer Biology 2021

  Quote: Pooled guide RNA plasmids (commercially obtained from Santa Cruz Biotechnology; Cat# sc-402236-KO-2) were used ...
• Antibodies control metabolism by regulating insulin homeostasis

  Timm Amendt, et al., bioRxiv - Immunology 2021

  Quote: ... Chemical thiol-crosslinking was done using 1,2-Phenylen-bis-maleimide (Santa Cruz, 13118-04-2) at 100 μg/mL for 48 h at room temperature (dark ...
• An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish

  Dianne Lumaquin, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cells were fixed with 2% paraformaldehyde (Santa Cruz Biotechnology, Santa Cruz, USA, Catalog #sc-281692) for 45 minutes ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Coverslips were mounted onto slides using Vectashield medium (ThermoFisher ...
• Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia

  Laura R. Nementzik, et al., bioRxiv - Neuroscience 2023

  Quote: ... The ubiquilin 2 antibody used here (mouse monoclonal anti-ubiquilin IgG2a, Santa Cruz #SC-100612) has been used by us previously for the detection of neuropathological aggregates [18 ...
• The Cytomegalovirus M35 Protein Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes by Direct Promoter Binding

  Hella Schwanke, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HRP-coupled GFP-antibody (clone B-2, #sc-9996 HRP) was purchased from Santa Cruz Biotechnology (Heidelberg ...
• Structure and activity of botulinum neurotoxin X

  Markel Martínez-Carranza, et al., bioRxiv - Biochemistry 2023

  Quote: ... Primary antibodies used were against VAMP-2 (custom made) and VAMP4 (Santa Cruz sc-365332). The secondary antibodies were HRP-conjugated ant-rabbit IgG (Sigma A6154 ...
• In-utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome

  Tinna Reynisdottir, et al., bioRxiv - Genetics 2024

  Quote: ... Samples were washed 2×10 minutes with TBS-T (1x TBS (Santa Cruz, sc-24951) with 0.05% Triton X-100 (Sigma-Aldrich ...
• Calmodulin enhances mTORC1 signaling by preventing TSC2-Rheb binding

  Yuna Amemiya, et al., bioRxiv - Biochemistry 2024

  Quote: ... Anti-Myc (9E10, sc-40), anti-GFP (B-2, sc-9996) were from Santa Cruz Biotechnology (Dallas ...
• CK1α, FAM83H, and FAM83B contribute to bundling of neurofilaments and are sequestered in cellular and mice models of ARSACS

  Caitlin S. Atkinson, et al., bioRxiv - Cell Biology 2024

  Quote: ... FAM83B (sc-415158, Santa-Cruz Biotechnology) or CK1α (sc-400898-KO-2, Santa Cruz Biotechnology) and EGFP ...
• Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement

  Haneen S. Alsehli, et al., bioRxiv - Cell Biology 2023

  Quote: ... goat anti-SOX17 (R&D, 1:50) were diluted and YAP 1 (Santa Cruz, 1:50) were diluted in the blocking buffer and incubated for 48 h in the dark at 4°C on a shaker ...
• Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

  Man Zhu, et al., bioRxiv - Biochemistry 2024

  Quote: ... Poly (ADP-ribose) polymerase-1 (PARP-1, 1:1000; Catalog# sc-8007; SANTA CRUZ BIOTECHNOLOGY, INC.), TFEB (1:3000 ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... followed by incubation overnight with primary antibodies (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) at 4 degree or for 1hr at 37 °C ...
• rRNA Biogenesis Regulates Mouse 2C-like State by 3D Structure Reorganization of Peri-Nucleolar Heterochromatin

  Hua Yu, et al., bioRxiv - Cell Biology 2021

  Quote: ... for 10 min at RT and then stained with a primary antibody (1:200, Nucleolin, CST, 145745; 1:400, NPM1, Sigma, B0556; 1:200, Fibrillarin, Abcam, ab4566; RPA194, 1:50, Santa Cruz, sc-48385) for 12 h at 4 °C ...
• Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation domains in mammalian cells

  Pierre-Olivier Estève, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 200 µg of chromatin cell lysate was incubated with 5 µg of anti-SET8 (sc-515433, Santa Cruz). IP reactions were performed and blotted with anti-PARP1 and anti-SET8 antibodies as described above.
• CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre

  Tsuyoshi Imasaki, et al., bioRxiv - Cell Biology 2021

  Quote: ... The purified tubulin was labelled with 5(6)-carboxytetramethylrhodamine succinimidyl ester (TMR) (Santa Cruz Biotechnology, Dallas, TX, USA) or N-[6-(biotinamide)hexanoyl]-6-aminohexanoic acid N-succinimidyl ester (Biotin-LC-LC-NHS ...
• The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2

  Ana Domingo-Muelas, et al., bioRxiv - Neuroscience 2022

  Quote: ... 5-10 µg of antibody (rabbit anti-p27, Santa Cruz sc-528; goat anti-SOX2, R&D AF2018) or non-related antibody (NRA ...
• Basal G-protein-gated inwardly rectifying potassium (Kir3/GirK) channels activity governs synaptic plasticity that supports dorsal hippocampus-dependent cognitive functions

  Sara Temprano-Carazo, et al., bioRxiv - Neuroscience 2020

  Quote: ... the tissue was incubated for 5 min in 0.01 % DAPI (#sc-3598, Santa Cruz Biotechnology, Santa Cruz, US) in TBS ...
• Basal G-protein-gated inwardly rectifying potassium (Kir3/GirK) channels activity governs synaptic plasticity that supports dorsal hippocampus-dependent cognitive functions

  Sara Temprano-Carazo, et al., bioRxiv - Neuroscience 2020

  Quote: ... the tissue was incubated for 5 min in 0.01 % DAPI (#sc-3598, Santa Cruz Biotechnology, Santa Cruz, US) in TBS ...
• NEK1 haploinsufficiency worsens DNA damage but not defective ciliogenesis in C9ORF72 patient-derived iPSC-motoneurons

  Serena Santangelo, et al., bioRxiv - Neuroscience 2024

  Quote: ... Membranes were blocked with 5% (w/v) non-fat dry milk in Tris-buffered saline (Santa Cruz Biotechnology) with Tween-20 (Sigma-Aldrich ...
• Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting

  Xiangyu Gong, et al., bioRxiv - Bioengineering 2023

  Quote: The EC-patches and EC-strips were fixed on Day 5 with 4% Paraformaldehyde (PFA, Santa Cruz Biotechnology) for 10 minutes and then washed with PBS three times ...
• MEMO1 is a Metal Containing Regulator of Iron Homeostasis in Cancer Cells

  Natalia Dolgova, et al., bioRxiv - Biochemistry 2023

  Quote: ... blocked in 5% BSA in PBS overnight and incubated with anti-GRP75 antibodies (D-9, Santa Cruz Biotechnology) for 1 h at room temperature ...
• 0JAK Inhibitor Withdrawal Causes a Transient Proinflammatory Cascade: A Potential Mechanism for Major Adverse Cardiac Events

  Ilya Gurevic, et al., bioRxiv - Immunology 2024

  Quote: ... the membranes were blocked with 5% non-fat dry milk (cat. #sc-2325, Santa Cruz Biotechnology, Dallas, TX) in TBST (for phospho and total TYK2 ...
• Proximity-based activation of AURORA A by MPS1 potentiates error correction

  Nelson Leça, et al., bioRxiv - Cell Biology 2024

  Quote: ... monopolar cells were induced by inhibiting Eg5 using 5 µM S-Trityl-L-Cysteine (STLC; Santa Cruz Biotechnology) which was added to the medium 5 h before fixation ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Samples were then subjected to SDS-PAGE and Western blotting using ARaf Antibody (A-5) (Santa Cruz Biotechnology), BRaf Antibody (F-7 ...
• Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma

  Annie Li, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The target cells were transduced in media containing 5 ug/ml of polybrene (SC-134220 Santa Cruz technologies) for 24 h and afterwards selected with puromycin for 48 h.
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-fibromodulin (1:500, 1% casein, sc-33772, Santa Cruz), anti-pSer2448-mTOR (1:1000 ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... anti-human Caspase-1 (Santa Cruz, sc515, 1: 1,000 dilution), anti-human GSGMD (sigma ...
• RhoA- and Ran-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

  Benoit Dehapiot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Rock-1 (1/100, Goat polyclonal; Santa Cruz sc-6056). Secondary antibodies were Alexa Fluor 488-conjugated donkey anti-goat ...
• CDK5 influences the organization of the Circadian Machinery in peripheral clocks

  Jürgen Ripperger, Urs Albrecht, Andrea Brenna, bioRxiv - Molecular Biology 2021

  Quote: ... while Tubulin by Abcam (1:1000) and Lamin B by Santa Cruz (1:1000). The day after ...
• GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

  Ari W. Schaler, et al., bioRxiv - Neuroscience 2020

  Quote: ... CamKIIα (1:2000, A-1, sc13141) was from Santa Cruz Biotechnology ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Phenomenon of music-induced opening of the blood-brain barrier in healthy mice

  O. Semyachkina-Glushkovskaya, et al., bioRxiv - Neuroscience 2020

  Quote: ... ZO-1 (1:500; Santa Cruz Biotechnology, Santa Cruz, USA), OCC and NG2 (1:500 ...
• Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

  Joana Sá-Pessoa, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-Cullin-1 (1:200, Santa Cruz Biotechnology sc-12761), anti-Flag M2 (1 μg ...
• Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

  Robin M. Delaine-Smith, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GLI-1 Antibody (C-1, sc-515751) from Santa Cruz Biotechnology.
• Reliance of neuronal gene expression on cohesin scales with chromatin loop length

  Lesly Calderon, et al., bioRxiv - Genomics 2022

  Quote: ... CUX-1 (1:400; rabbit polyclonal sc-13024, Santa Cruz) and anti phospho-histone H3 (Ser10 ...
• The phospho-regulated amphiphysin/endophilin interaction is required for synaptic vesicle endocytosis

  Christiana Kontaxi, Michael A. Cousin, bioRxiv - Neuroscience 2023

  Quote: ... goat syndapin 1 (1:1000; Santa Cruz Biotechnology, sc-10412), and mouse PSD95 (1:1000 ...
• Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors

  Adam Myszczyszyn, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-Zo-1 (1:200, Santa Cruz, sc-33725), mouse anti-MDR1 (1:50 ...
• Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

  James L. Daly, et al., bioRxiv - Neuroscience 2022

  Quote: ... VPS29 (Santa Cruz; D-1; sc-398874; 1:500 WB), VPS35 (Abcam ...
• Vitamin C is an efficient natural product for prevention of SARS-CoV-2 infection by targeting ACE2 in both cell and in vivo mouse models

  Yibo Zuo, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Ubiquitin (Ub) (Santa Cruz, 12987-1-AP, 1:1000), anti-K48 Ub (Cell Signaling Technology ...
• A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons

  Monika Moissidis, et al., bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-PGC-1⍺ (1:200, Santa Cruz #sc-518025), mouse anti-Kv1.1 (1:1,000 ...
• Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

  Stacia M. Dolliver, et al., bioRxiv - Microbiology 2022

  Quote: ... TIA-1 (1:200; goat, Santa Cruz Biotechnology, sc-1751); TIAR (1:1000 ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... ARMC8 (E-1, sc-365307; Santa Cruz Biotechnology, 1:500), WDR26 (ab85962 ...
• The large GTPase Guanylate-Binding Protein-1 (GBP-1) promotes mitochondrial fission in glioblastoma

  Ryan C. Kalb, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti-GBP-1 (1b1) (1:25; Calbiochem or Santa Cruz), anti-myc (1:50 ...