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701 - 750 of 8293 citations for 4 3 2 Chloroethyl 3 nitrosoureido tetrahydro 2H thiopyran 1 1 dioxide since 2020

• G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

  Yi-Hong Li, et al., bioRxiv - Immunology 2024

  Quote: ... The membranes then were incubated at 4◦C overnight with the primary antibodies diluted in the blocking buffer (rabbit anti-NLRP3 1:1000, Abcam, ab263899; rabbit anti-Gsdmd 1:1000, Abcam, ab219800; mouse anti-caspase-1 1:1000, Santa Cruz Biotechnology ...
• Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

  Tolulope Sokoya, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-LAMP-1 (Santa Cruz, sc-20011; IB 1:1,000; IF 1:400), HRP-conjugated goat anti-rabbit IgG (Thermo Fisher Scientific ...
• The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation

  Tiphaine Douanne, et al., bioRxiv - Immunology 2020

  Quote: ... Antibodies against HOIL1 (H-1, 1:1,000), GAPDH (6C5, 1:20,000) were from Santa Cruz. Antibodies to phosphorylated IκBα (5A5 ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... HRAS (1:1000, 18295-1-AP; GAPDH (1:20000, sc-32233; Santa Cruz Biotechnology, Inc.) and rabbit antibodies specific for p-Erk1/2 (phospho-p44/42 MAPK ...
• Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

  Austin Stoner, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-LAMP-1 (1D4B) (lysosome-associated membrane protein 1; Santa Cruz sc-19992; 1:500) anti-IBA1 (ionized calcium-binding adapter molecule 1 ...
• Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

  Andrea Sacchetti, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Cells were then exposed overnight at 4 °C to primary antibodies against EpCAM (mouse, 1:250; sc-66020; Santa Cruz Biotechnology) and ZEB1 (rabbit ...
• On the objectivity, reliability, and validity of deep learning enabled bioimage analyses

  Dennis Segebarth, et al., bioRxiv - Neuroscience 2020

  Quote: ... sections were treated at 4°Covernight with a primary anti-body (rabbit anti-cFOS, 1:500, Santa Cruz Biotechnology, California, USA) diluted in blocking solution ...
• Amplification of potential thermogenetic mechanisms in cetacean brains

  Paul R. Manger, et al., bioRxiv - Neuroscience 2020

  Quote: ... The blots were incubated over night at 4°C under gentle agitation in the primary antibody solutions (1:300 goat anti-UCP1, Santa Cruz Biotechnology ...
• Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells

  Marianne R. Spalinger, et al., bioRxiv - Microbiology 2020

  Quote: ... 1% BSA in tris-buffered saline with 0.5% Tween) for 1 h and incubated over night at 4°C with anti-ACE2 (Clone E-11, Santa Cruz Biotechnology), anti-phospho-STAT1 (Tyr701 ...
• Potential therapy for progressive vision loss due to PCDH15-associated Usher Syndrome developed in an orthologous Usher mouse

  Saumil Sethna, et al., bioRxiv - Neuroscience 2021

  Quote: ... and incubated overnight at 4°C with the indicated primary antibodies to transducin (1:100 dilution, #Sc-517057, Santa Cruz Biotechnology) and arrestin (clone C10C10 ...
• TRPC5-Ca_V3 complex mediates Leptin-induced excitability in hypothalamic neurons

  Paula P. Perissinotti, et al., bioRxiv - Neuroscience 2020

  Quote: ... Samples were then processed by addition of the primary antibody and incubation for 1 h at 4°C [antibodies: α1H (Santa Cruz Biotechnology ...
• AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

  A Kneppers, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cells were then incubated overnight at 4°C with primary antibodies directed against Myogenin (MyoG; Santa Cruz #SC-12732; 1:50) or Desmin (Abcam #Ab32362 ...
• Cellular and computational models reveal environmental and genetic interactions in MMUT-type methylmalonic aciduria

  Charlotte Ramon, et al., bioRxiv - Systems Biology 2022

  Quote: ... overnight at 4°C diluted 1:500 in blocking buffer and incubated with secondary antibodies (anti-mouse HRP, Sc516102-CM, Santa Cruz) diluted 1:5000 in blocking buffer for one hour at RT ...
• The LH receptor regulates hippocampal spatial memory and restores dendritic spine density in ovariectomized APP/PS1 AD mice

  Megan Mey, et al., bioRxiv - Neuroscience 2023

  Quote: ... Membranes were incubated in primary antibodies overnight in 1X TBST at 4°C: BDNF (1:2,000; Santa Cruz Biotechnology, Texas/USA), Rac1 (1:1,000 ...
• Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

  Abby R Kroken, et al., bioRxiv - Microbiology 2023

  Quote: ... Membrane was blocked with Bio-Rad EveryBlot block and probed with anti-caspase-4 antibody (Santa Cruz, sc-56056, 1:1000). Blot was washed using TBST ...
• Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

  Amy H. Chan, et al., bioRxiv - Immunology 2023

  Quote: ... 2012) and the following reagents: antibodies against the caspase-4 large subunit (4B9, mouse monoclonal antibody, 1:1000; Santa Cruz Biotechnology), human IL-1β (goat polyclonal antibody ...
• Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

  Amy H. Chan, et al., bioRxiv - Immunology 2023

  Quote: ... 2012) and the following reagents: antibodies against the caspase-4 large subunit (4B9, mouse monoclonal antibody, 1:1000; Santa Cruz Biotechnology), human IL-1β (goat polyclonal antibody ...
• Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations

  Elizabeth A Forrester, et al., bioRxiv - Physiology 2023

  Quote: ... Membranes were blocked for at least 0.5 hour in 3% BSA-PBS and incubated overnight at 4°C with the primary SGLT2 mouse monoclonal antibody (D-6, sc-393350, 1/200 dilution, Santa Cruz). The membranes were incubated with highly adsorbed horseradish peroxidase-conjugated goat anti-mouse IgG (A16078 ...
• Enhancing oncolytic virotherapy by exosome-mediated microRNA reprograming of the tumour microenvironment

  Victoria A. Jennings, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Blocked membranes were incubated overnight at 4°C with the following diluted antibodies: ALIX (1:2000; Santa Cruz Biotechnology, sc-53538), CD9 (1:1000 ...
• Pregnancy History and Estradiol Influence Spatial Memory, Hippocampal Plasticity, and Inflammation in Middle-aged Rats

  Tanvi A. Puri, et al., bioRxiv - Neuroscience 2024

  Quote: ... followed by a double overnight incubation at 4°C in Doublecortin and cFOS primary antibodies (1:1000 anti-Doublecortin goat polyclonal IgG, sc-8066, Santa Cruz Biotechnology ...
• Snorkel-tag Based Affinity Chromatography for Recombinant Extracellular Vesicle Purification

  Madhusudhan Reddy Bobbili, et al., bioRxiv - Bioengineering 2024

  Quote: ... the membrane was incubated overnight at 4°C or 1 hour at room temperature with primary antibody solution (CD81, Santa Cruz Biotechnology ...
• ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke

  Xianshu Ju, et al., bioRxiv - Neuroscience 2024

  Quote: ... Slices were rinsed with PBS and incubated overnight at 4°C with antibodies against CAMK II alpha (1:500; Santa Cruz) and ATF5 (1:500 ...
• Juvenile fluoxetine treatment affects the maturation of the medial prefrontal cortex and behavior of adolescent female rats

  Joanna Kryst, et al., bioRxiv - Neuroscience 2024

  Quote: ... the sections were incubated for 48 h at 4 °C with a goat anti-glial fibrillary acidic protein (GFAP) antibody (1:300; Santa Cruz) or a rabbit anti-ionized calcium-binding adapter molecule/allograft inflammatory factor 1 (IBA1/AIF-1 ...
• Diphenyleneiodonium chloride inhibits MYCN-amplified neuroblastoma by targeting MYCN induced mitochondrial alterations

  Soraya Epp, et al., bioRxiv - Cancer Biology 2024

  Quote: ... in TBS with 0.05% Tween (TBS-T) for 1 h and incubated overnight at 4°C with primary antibodies against MYCN (#sc-53993, Santa Cruz), GADPH (#2118 ...
• Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model

  Marianela Lasagna, et al., bioRxiv - Cancer Biology 2024

  Quote: ... the slides were incubated overnight at 4 °C with primary antibodies using mouse anti-PCNA (1:100, Santa Cruz Biotechnology, USA), mouse anti-β-catenin (1:50 ...
• Social recognition in rats and mice requires integration of olfactory, somatosensory and auditory cues

  Shani Haskal de la Zerda, et al., bioRxiv - Animal Behavior and Cognition 2020

  Quote: ... Then, the sections were placed in primary antibody mix (2% NGS, mouse monoclonal αOMP antibodies (1:500; Santa Cruz) and PBS-t ...
• Opposing diet, microbiome and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host

  Gabriel Vasconcelos Pereira, et al., bioRxiv - Microbiology 2023

  Quote: ... the tissue was covered with a 1:200 dilution of Mucin 2 antibody (H-300) (Santa Cruz Biotechnology, USA) in blocking buffer and incubated for two hours at room temperature ...
• GRIN2B disease-associated mutations disrupt the function of BK channels and NMDA receptor signalling nanodomains

  Rebeca Martínez-Lázaro, et al., bioRxiv - Physiology 2024

  Quote: ... mouse anti-α1 Na+,K+-ATPase (ATP1A1) monoclonal antibody F-2 (sc-514614, Santa Cruz Biotechnology; 1:1000 dilution) mouse anti-tubulin monoclonal antibody AA13 (T8203 ...
• Physioxia-modulated mesenchymal stem cells secretome has higher capacity to preserve neuronal network and translation processes in hypoxic-ischemic encephalopathy in vitro model

  Inês Caramelo, et al., bioRxiv - Neuroscience 2024

  Quote: ... membranes were incubated with the following primary antibodies (MAP-2 1:1000 #sc-74421, Santa Cruz; Cleaved PARP (Asp14) 1:3000 #94885 ...
• Neurovascular unit adjustments following chronic distress explain motivational deficits in mice

  Lidia Cabeza, et al., bioRxiv - Neuroscience 2024

  Quote: ... co-staining IBA-1 – ZO-1 incubation during 24 h at room temperature (1:1000, ab178846, rabbit anti-IBA-1, Abcam; 1:200, sc-33725, rat anti-ZO-1, Santa Cruz Biotechnology); and GFAP incubation during 24 h at room temperature (1:1000 ...
• A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels

  Apurva T. Prabhakar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Nuclear DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI) (Santa Cruz, catalog no. sc-3598) and the coverslips were mounted on a glass slide using Vectashield mounting medium (ThermoFisher) ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p53(DO-1) (1:1000, Santa Cruz, sc-126), anti-Drosophila Nmnat (1:3000) ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-IBA-1 (Santa Cruz Biotechnology sc-32725; 1:200), α-TNFα (Santa Cruz Biotechnology sc-52749 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-PARP-1 (Santa Cruz Biotechnology sc-7150; 1:200), α-Caspase 3 (Santa Cruz Biotechnology sc-7148 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-IBA-1 (Santa Cruz Biotechnology sc-32725; 1:50), α-Tubulin β 3 (Tuj1 ...
• Myocardial matrix material supports a proliferative microenvironment for cardiomyocytes

  Raymond M. Wang, et al., bioRxiv - Bioengineering 2020

  Quote: ... mouse PCM-1 (1:200, Santa Cruz, sc-398365), α-actinin (1:800 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... HSP60 (1:500, Santa Cruz Biotechnology, clone H-1), GAPDH (1:5,000 ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-centrin-1 1:500 (Santa Cruz Biotechnology) for one hour at RT ...
• Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models

  Oxana V. Denisova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PME-1 (Santa Cruz Biotechnology, sc-20086, 1:1000), phospho PDHE1α S300 (Millipore ...
• Aiolos modulates the T_FH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25

  Kaitlin A. Read, et al., bioRxiv - Immunology 2022

  Quote: ... mouse anti-rabbit:HRP (Santa Cruz, 1:5000-1:20,000).
• Human DICER helicase domain recruits PKR and modulates its antiviral activity

  Thomas C. Montavon, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-hADAR-1 (1:500 Santa Cruz sc-271854) anti-p-PKR (1:1000 Abcam ab81303 ...
• Nuclear Hormone Receptor NHR-49 controls a HIF-1-independent hypoxia adaptation pathway in Caenorhabditis elegans

  Kelsie R. S. Doering, et al., bioRxiv - Genetics 2021

  Quote: ... 1 mM IPTG (Santa Cruz CAS 367-93-1), and 12.5 μg/ml tetracycline (BioBasic TB0504 (NGM-RNAi plates) ...
• CRISPR-mediated correction of skeletal muscle Ca²⁺ handling in a novel DMD patient-derived pluripotent stem cell model

  Cristina Morera, et al., bioRxiv - Cell Biology 2022

  Quote: ... Tra-1-60 (Santa Cruz, sc-21705; 1:100), SSEA4 (BD Bioscience ...
• Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans

  Junran Yan, et al., bioRxiv - Genetics 2024

  Quote: ... 1 mM IPTG (Santa Cruz CAS 367-93-1), and 12.5 μg/ml tetracycline (BioBasic TB0504 ...
• Ketosis Prevents Abdominal Aortic Aneurysm Rupture Through CCR2 Downregulation and Enhanced MMP Balance

  Sergio Sastriques-Dunlop, et al., bioRxiv - Pathology 2023

  Quote: ... and Caveolin-1 (Santa Cruz # sc-53564, 1:1000) were used as loading controls ...
• Establishment of Bovine Trophoblast Stem Cells

  Yinjuan Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-PL-1(Santa Cruz, sc-376436; 1:200) and anti-PTGS2 (Sigma ...
• LOX-1 and MMP-9 inhibition attenuates the detrimental effects of delayed rt-PA therapy and improves outcomes after acute ischemic stroke

  Kajsa Arkelius, et al., bioRxiv - Neuroscience 2023

  Quote: ... VCAM-1 (1:500 #sc-13160 Santa Cruz Biotechnology), diluted in 5% bovine serum albumin (BSA ...
• BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss

  Mario A. Shields, et al., bioRxiv - Pathology 2023

  Quote: ... Zo-1 (Santa Cruz Biotech #sc-33725, 1:200), Amylase (Santa Cruz Biotech #sc-46657 ...
• p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners

  Anamari Brdar, et al., bioRxiv - Biophysics 2024

  Quote: ... anti-p53 (DO-1, Santa Cruz Biotechnologies, 1:1000), anti-Vinculin (clone 7F9 ...
• Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

  Swagata Konwar, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and TSP-1 (1:100, Santa Cruz sc-59887) for immunofluorescence imaging.