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551 - 600 of 8080 citations for 7 bromo 1 methyl 1 3 dihydro 2H benzo d imidazol 2 one since 2020

• PEAK3 pseudokinase represents a pro-migratory and -invasive signalling scaffold

  Jianmei Hou, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 14-3-3 (Santa Cruz Biotechnology, cat. sc-1657), PTPN12 (Abcam ...
• Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

  Hudson W. Coates, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse monoclonal anti-pan-14-3-3 (Santa Cruz Biotechnology sc-1657 ...
• Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB

  Ling-Yun Zhou, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Mrtfa (G-7, sc-398675, Santa Cruz Biotechnology), mouse anti-MKL2/Mrtfb (CL1546 ...
• Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB

  Ling-Yun Zhou, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Lmo7 (B-7, sc-376807, Santa Cruz Biotechnology), rabbit anti-Triobp (16124-1-AP ...
• CRISPRa screen identifies a role for c-KIT signaling in tamoxifen resistance, potentially through upregulation of ABC transporters

  Brooke A. Marks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Anti-HA tag (F-7) (Santa Cruz; cat # sc-7392) and B-Actin (AbCam ...
• The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia

  Swapnil Rohidas Shinde, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Vps28 (mouse; sc-166537, clone E-7; Santa Cruz). The following polyclonal antibodies were used for immunofluorescence ...
• Multidimensional Characterization of Soft-Tissue Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions

  Julia Schöpf, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HA-Tag (F-7) mouse mAb (Santa Cruz, sc-7392), anti-histone H3 (acetyl K27 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... were loaded with BRaf Antibody (F-7, Santa Cruz Biotechnology), with the following protocol ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... were loaded with BRaf Antibody (F-7, Santa Cruz Biotechnology), with the following protocol ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... were loaded with BRaf Antibody (F-7, Santa Cruz Biotechnology), with the following protocol ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... were loaded with BRaf Antibody (F-7, Santa Cruz Biotechnology) or ARaf Antibody (A-5 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: BRaf Antibody (F-7) (Santa Cruz Biotechnology, cat. no. 5284)
• Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

  Amy Tarangelo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... human p53 (Cat #SC-126, DO-1, Santa Cruz, 1:1000), p21 C’-terminus (Cat# 2947 ...
• Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

  Stefanie Koster, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse-anti-p53 (DO-1) (1:500, Santa Cruz, # sc-126), mouse-anti-Chlamydia Hsp60 (A57-E4 ...
• Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

  Yulia Steblyanko, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-PRC1 (C-1) (1:500; Santa Cruz, sc-3769839), mouse anti-NDC80/HEC1 (1:2000 ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-LOX (1:500, 1% casein, sc-32409, Santa Cruz). Anti-rabbit IgG HRP (NA934V ...
• Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation

  Stine Kjær Morthorst, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-PALS-1 (Santa Cruz, cat#sc-365411; 1:50), goat anti-MYC (Abcam ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Importin β-1 (Santa Cruz sc-11367, 1:50), goat anti-Lamin B (Santa Cruz sc-6217 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Importin β-1 (Santa Cruz sc-1863, 1:50), mouse anti-Importin β-1 (Santa Cruz sc-137016 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Importin β-1 (Santa Cruz sc-137016, 1:50), rabbit anti-Importin β-1 (Santa Cruz sc-11367 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Importin β-1 (Santa Cruz sc-1863, 1:50), mouse anti-Importin β-1 (Santa Cruz sc-137016 ...
• CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

  Lisa Crozier, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse anti-p53 (DO-1) (Santa Cruz, sc-126; 1/1000), rabbit anti-actin (Sigma ...
• Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

  Hyosung Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-VCAM-1 (1:200 dilution, sc-13160, Santa Cruz), goat anti-VE-cadherin (1:300 dilution ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti-Ku86 (Santa Cruz, B-1, sc-5280; 1:500), mouse anti-α-tubulin (Millipore ...
• Extended longevity geometrically-inverted proximal tubule organoids for protein uptake studies

  Eric Parigoris, et al., bioRxiv - Bioengineering 2022

  Quote: ... mouse anti-aquaporin-1 (Santa Cruz #sc-32737, 1:200 dilution), mouse anti-ezrin/villin-2 (BD #610602 ...
• Pharmacological tuning of microRNAs in FAP-derived Extracellular Vesicles by HDAC inhibitors promotes regeneration and reduces fibrosis in dystrophic muscles

  M. Sandonà, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-Flotillin-1 (1/200, H-104, Santa Cruz Biotechnology), mouse anti-Alix (3A9 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Importin β-1 (Santa Cruz sc-137016, 1:1000) and mouse anti-Ran-GTPase (BD Biosciences 610340 ...
• Loss of C9orf72 perturbs the Ran-GTPase gradient and generates compositionally diverse cytoplasmic Importin β-1 granules in motor and cortical neurons in vivo

  Philip McGoldrick, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Importin β-1 (Santa Cruz sc-137016, 1:50), mouse anti-KPNA (BD Biosciences 610485 ...
• Murine blastocysts generated by in vitro fertilization show increased Warburg metabolism and altered lactate production

  Seok Hee Lee, et al., bioRxiv - Developmental Biology 2022

  Quote: ... monocarboxylic acid transporter 1 (MCT1, 1:200; sc-365501, Santa Cruz), lactate dehydrogenase A (LDHA ...
• Stress-relief function of migrasomal autophagosome formed by inhibition of autophagosome/lysosome fusion

  Seon Yong Lee, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Beclin-1 (1:1000; Santa cruz Biotechnology, Cat. # sc-48341), anti-ATG7 (1:500 ...
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: FBL (B-1) Mouse mAb (1:500, Santa Cruz, sc-166001)
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: BOP1 (E-1) Mouse mAb (1:250, Santa Cruz, sc-390672)
• Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

  Ryan Houston, et al., bioRxiv - Cell Biology 2020

  Quote: p53 (DO-1) Mouse mAb (1:5000, Santa Cruz, sc-126)
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... and TRA-1-60 (sc-21705, Santa Cruz Biotechnology, 1:100). Those for intracellular antigens were diluted in Medium B for permeabilization ...
• Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

  Thomas Geuens, et al., bioRxiv - Bioengineering 2020

  Quote: ... and TRA-1-60 (sc-21705, Santa Cruz Biotechnology, 1:100). After overnight incubation ...
• NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

  Carolina Marques, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Incubations with anti-FRA-1 (Santa Cruz #sc-183, 1:100) and anti-CD44 (BD Biosciences #550538 ...
• Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility

  José Alexandre Salerno, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Sigma-1 R (1:500; SC-137075 - Santa Cruz Biotechnology), anti-actin (1:2000 ...
• CREB-mediated transcriptional activation of NRMT1 drives muscle differentiation

  John G. Tooley, et al., bioRxiv - Biochemistry 2021

  Quote: ... mouse anti-ATF2 (F2BR-1) (1:1000; sc-242, Santa Cruz), rabbit anti-SRF (D71A9 ...
• Molecular basis of functional compatibility between ezrin and other actin-membrane associated proteins during cytokinesis

  Guang Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-anillin #1 (sc-271814, Santa Cruz Biotechnology; 1:100), goat anti-anillin #2 (sc-54859 ...
• Regenerative growth is constrained by brain tumor to ensure proper patterning in Drosophila

  Syeda Nayab Fatima Abidi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-dMyc (1:500 or 1:250) (Santa Cruz Biotechnologies), mouse anti-βgal (1:100 ...
• Chronic intermittent hypoxia induced-dysmetabolism is associated with hepatic oxidative stress, mitochondrial dysfunction and inflammation

  Joana L. Fernandes, et al., bioRxiv - Physiology 2023

  Quote: ... interleukin 1 receptor (IL1R) (1:100, Santa Cruz Biotechnology, Madrid, Spain), tumor necrosis factor alfa receptor (TNF-αR ...
• Microglial colonisation of the developing brain is facilitated by clonal expansion of highly proliferative progenitors and follows an allometric scaling

  Liam Barry-Carroll, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-PU.1 (Santa Cruz Biotechnology; sc-352; 1:500), rabbit anti-Caspase3 (Merck Millipore ...
• EPAC1 inhibition protects the heart from doxorubicin-induced toxicity

  Marianne Mazevet, et al., bioRxiv - Pathology 2022

  Quote: ... SERCA2A (1/1000) and anti-Actin (1/50000) from Santa Cruz Biotechnology (Heidelberg ...
• N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

  Sylvia Varland, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-p62/SQSTM1 (Santa Cruz, sc-28359, 1:300-1:1000), anti-LC3B (Thermo Scientific ...
• D-mannose suppresses macrophage release of extracellular vesicles and ameliorates type 2 diabetes

  Sha Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Cav-1 (Santa Cruz Biotechnology, USA; diluted at 1:1000), anti-Mitofilin (Abcam ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... Rock-1 (K-18) (1:100; Santa Cruz Biotechnology sc-6056), Trimethylhistone H3 (Lys4 ...
• Misaligned chromosomes that satisfy the spindle assembly checkpoint are a strong predictor of micronuclei formation in dividing cancer cells

  Ana Margarida Gomes, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-Sgo-1 (F-8) (1:1000; Santa Cruz Biotechnology), rabbit anti-DHC (1:500 ...
• Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental development

  Athilakshmi Kannan, et al., bioRxiv - Physiology 2023

  Quote: ... placental lactogen 1 (PL1, 1:200, Santa Cruz Biotechnology, SC-34713), PLF (Santa Cruz ...
• Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity

  Irene Schwartz, et al., bioRxiv - Cell Biology 2024

  Quote: ... Lamin A/C Antibody (E-1) (Santa Cruz Biotechnology, 1:1000), Monoclonal Anti-Vinculin antibody (Sigma-Aldrich ...
• Virus-induced paraspeckle-like condensates are essential hubs for gene expression and their formation drives genomic instability

  Katherine L. Harper, et al., bioRxiv - Microbiology 2024

  Quote: ... ORF57 (Santa Cruz sc-135747, WB 1/1000, IF 1/100), ORF65 (CRB crb2005224 ...