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551 - 600 of 1983 citations for 2' 5' Dichloro 3 3 4 dimethylphenyl propiophenone since 2020

• An extra-glycolytic function for hexokinase 2 as an RNA-binding protein regulating SOX10 mRNA translation in melanoma

  Ana Luisa Dian, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-ACOT1/2 (Santa Cruz Biotechnology ...
• CALR frameshift mutations in MPN patient-derived iPS cells accelerate maturation of megakaryocytes

  Kathrin Olschok, et al., bioRxiv - Cancer Biology 2021

  Quote: ... OCT3/4 (H-134, Santa Cruz, CA, USA) or mouse monoclonal antibody CAL2 (Dianova ...
• iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

  Alba Tristán-Noguero, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-OCT3/4 (1:25; Santa Cruz), rabbit anti-Sox2 (1:100 ...
• Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

  Michelle Dookwah, et al., bioRxiv - Neuroscience 2021

  Quote: ... Anti-SSEA3/4 antibody (Santa Cruz, # sc-21704), 1:200 dilution in 5% donkey serum in PBS-T ...
• A GRAB sensor reveals activity-dependent non-vesicular somatodendritic adenosine release

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2020

  Quote: ... S-(4-nitrobenzyl)-6-thioinosine (NBTI, Santa Cruz), dipyridamole (Santa Cruz) ...
• TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

  Yujiao He, et al., bioRxiv - Cell Biology 2021

  Quote: ... and RanBP2 (D-4) were from Santa Cruz Biotechnology ...
• UBC9 and EME1 sumoylation foster ribosomal DNA damage repair in CPT response

  Easa Nagamalleswari, et al., bioRxiv - Molecular Biology 2022

  Quote: ... fixed with 4% paraformaldehyde (PFA) (SC281692, Santa Cruz) in PBS for 25 minutes at room temperature before staining the cells with the respective antibodies as described above.
• Clinically-relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance

  Adriana Mañas, et al., bioRxiv - Cancer Biology 2022

  Quote: ... etoposide (4 mg/kg; Santa Cruz, sc-3512) and cyclophosphamide (75 mg/kg ...
• Generation and Maturation of Human iPSC-derived Cardiac Organoids in Long Term Culture

  Ece Ergir, et al., bioRxiv - Cell Biology 2022

  Quote: ... and fixed in 4% PFA (Santa Cruz Biotechnology) supplemented with 0.03% eosin (Sigma Aldrich ...
• Fasciola hepatica juveniles interact with the host fibrinolytic system as a potential early-stage invasion mechanism

  Judit Serrat, et al., bioRxiv - Molecular Biology 2022

  Quote: ... FhNEJ were fixed in 4% paraformaldehyde (Santa Cruz) for 1 hour at room temperature and probed with 13 μg/ml of anti-human PLG antibody raised in sheep (Innovative Research ...
• Following embryonic stem cells, their differentiated progeny, and cell-state changes during iPS reprogramming by Raman spectroscopy

  Arno Germond, et al., bioRxiv - Systems Biology 2020

  Quote: ... fixed with 4% PFA (Santa Cruz #sc-281692) for 15 min at room temperature and permeabilized with 0.5% Triton in PBS with 10% FBS addition for 30 min ...
• The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes

  Görkem Garipler, et al., bioRxiv - Developmental Biology 2020

  Quote: ... OCT3/4 (Sc-5279, Santa Cruz; 2mg/ml), GFP (ab13970 ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... polyclonal BMP2/4 (Santa Cruz; sc6267, Texas, USA), monoclonal pSMAD 2/3 (Cell Signaling ...
• Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma

  Ryan M. Samuel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... cells were fixed with 4% PFA (Santa Cruz) for 30 min at room temperature ...
• Inactivating Negative Regulators of Cortical Branched Actin Enhances Persistence of Single Cell Migration

  Artem I. Fokin, et al., bioRxiv - Cell Biology 2023

  Quote: ... p62/DCTN4 clone H-4 (Santa Cruz Biotechnology). For immunofluorescence anti-Laminin V ...
• Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression

  Dylan Murphy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-Gata-4 (Santa Cruz, 1:100), rabbit anti-NANOG (Bethyl ...
• ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation

  Justin L. Korfhage, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-WIPI-4 (Santa Cruz Biotechnology; sc398272), rabbit anti-LC3B (D11 ...
• Multi-level monitoring of EME1-MUS81 in CPT induced nucleolar rDNA repair

  Karishma Bakshi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... fixed with 4% paraformaldehyde (PFA) (SC281692, Santa Cruz) in PBS for 25 minutes at room temperature before staining the cells with the respective antibodies as described above ...
• Structure and dynamics of a pentameric KCTD5/Cullin3/Gβγ E3 ubiquitin ligase complex

  Duc Minh Nguyen, et al., bioRxiv - Biochemistry 2023

  Quote: ... and anti-Gb1-4 (sc-378, Santa Cruz) antibodies respectively.
• A mouse model of TB-associated lung fibrosis reveals persistent inflammatory macrophage populations during treatment

  Julie Boucau, et al., bioRxiv - Microbiology 2024

  Quote: ... then fixed with 4% paraformaldehyde (Santa Cruz Biotechnology), and filtered through a 70µm filter (BD biosciences ...
• Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant

  Elena Hernández-Gerez, et al., bioRxiv - Cell Biology 2024

  Quote: ... LLOMe (CAS 6491-83-4, Santa Cruz Biotechnology) was used at a final concentration of 2 mM in growth medium with FBS and antibiotics.
• Pyruvate from bone marrow mesenchymal stem cells supports myeloma redox homeostasis and anabolism

  Elías Vera-Sigüenza, et al., bioRxiv - Cancer Biology 2024

  Quote: ... MCT-4 (1:1000, Santa Cruz, sc-376140) and/or actin (1:4000 dilution ...
• Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjögren’s syndrome

  Jimin Yoon, et al., bioRxiv - Molecular Biology 2022

  Quote: ... cells were pretreated with 20 µM of 2-C′-methyladenosine (2-CM) (Santa Cruz Biotechnology) 24 h prior to poly I:C transfection.
• Bmf Facilitates Protein Degradation and Reduces Beclin1 Ubiquitination to Inhibit Autophagy Independent of mTOR

  Monica Delgado-Vergas, et al., bioRxiv - Cell Biology 2020

  Quote: ... We immunoprecipitated proteins with mouse anti Bcl-2 (C-2) (sc-7382 from Santa Cruz), rabbit anti Beclin1 (ab55878 from Abcam ...
• TRF1 poly(ADP-ribosyl)ation by PARP1 allows proper telomere replication through helicase recruitment in non-ALT cells

  C. Maresca, et al., bioRxiv - Molecular Biology 2021

  Quote: ... was immunoprecipitated (IP) overnight at 4°C with 4 μg of the anti-TRF1 antibody (goat Pab sc-1977, Santa Cruz) or the anti-WRN antibody (Rabbit Pab NB100-471 ...
• The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

  Valentine Clerc, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Chromatin was next immunoprecipitated overnight at 4°C with 4 μg of mouse anti-MYCN II antibody (sc53993, Santa Cruz Biotechnology) or an equivalent amount of the corresponding IgG Isotype control (ThermoFisher ...
• CTCF/cohesin organize the ground state of chromatin-nuclear speckle association

  Ruofan Yu, et al., bioRxiv - Genetics 2023

  Quote: Cells were washed twice with PBS and fixed with Paraformaldehyde solution 4% in PBS (Santa Cruz Biotechnology, CAS 30525-89-4) for 10 minutes at room temperature ...
• Pseudohypoxia-stabilized HIF2⍺ transcriptionally inhibits MNRR1, a druggable target in MELAS

  Neeraja Purandare, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and the remaining compounds (4-Aminobenzanilide, 4-Amino salicylic acid, benzanilide, phenyl benzoate, and phenyl salicylic acid) were from Santa Cruz Biotechnology (Dallas ...
• Multicellular Organoids of the Neurovascular Blood-Brain Barrier: A New Platform for Precision Neuronanomedicine

  Murali Kumarasamy, Alejandro Sosnik, bioRxiv - Bioengineering 2020

  Quote: ... claudin-5 (CLDN5, sc-374221, Santa Cruz), (v ...
• Type III interferons disrupt the lung epithelial barrier upon viral recognition

  Achille Broggi, et al., bioRxiv - Immunology 2020

  Quote: ... p21 (F-5) purchased from Santa Cruz. Live/dead cell markers Zombie Red™ (423109 ...
• Notch-1 mediates Epithelial-Mucosal Healing during Murine Colitis Recovery Phase

  Latika Luthra, et al., bioRxiv - Immunology 2022

  Quote: ... Lysozyme C (E-5, Santa Cruz Biotechnology) at 4 °C overnight ...
• Molecular characterization of Left-Right symmetry breaking in the mouse embryo

  Richard C.V. Tyser, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Primary antibodies (Goat Nkx2-5, Santa Cruz) were then added to the solution and were incubated o/n at 4°C ...
• Post-exposure intranasal IFNα suppresses replication and neuroinvasion of Venezuelan Equine Encephalitis virus within olfactory sensory neurons

  Matthew D. Cain, et al., bioRxiv - Immunology 2023

  Quote: ... 5% normal donkey serum (Santa Cruz Biotechnology) with 0.1% Triton X-100 (Sigma-Aldrich) ...
• Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics

  Thomas De Luca, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti α-actinin (clone H-2, 2 μg/mL, cat. no. sc-17829, Santa Cruz Biotechnology), anti-eIF2C (Argonaute1-4 ...
• Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics

  Thomas De Luca, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-tsg 101 (clone C-2, 2 μg/mL, cat. no. sc-7964, Santa Cruz Biotechnology), anti-Alix (clone 3A9 ...
• Rapid and precise genome engineering in a naturally short-lived vertebrate

  Ravi D. Nath, et al., bioRxiv - Genetics 2022

  Quote: ... extracted whole brain samples from 1–4-month-old animals were fixed overnight in 4% paraformaldehyde in PBS (Santa Cruz Biotechnology, SC281692) at 4°C and then washed for 12 hrs in 1xPBS (Corning ...
• Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells

  Veronica Martini, et al., bioRxiv - Immunology 2021

  Quote: ... for 15 mins at 4°C and then washed twice with PBS before fixation with 4% paraformaldehyde solution in PBS (Santa Cruz Biotechnology). Intracellular staining for the detection of Eomesodermin ...
• Matrix Stiffness Regulates Liver Sinusoidal Endothelial Cell Function Mimicking Responses in Fatty Liver Disease

  Vaishaali Natarajan, et al., bioRxiv - Bioengineering 2020

  Quote: ... anti-stabilin-2 (Santa Cruz, CA) or anti-GAPDH (Millipore ...
• State-dependent protein-protein interactions mediating 4-1BB CAR Signaling

  Samuel A. Ritmeester-Loy, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TRAF2 (F-2, Santa Cruz), anti-ZAP70 (D9H10 ...
• Single-cell transcriptomic analysis of antiviral responses and viral antagonism in Chikungunya virus-infected synovial fibroblasts

  Fabian Pott, et al., bioRxiv - Microbiology 2021

  Quote: ... MX1/2 (Santa Cruz sc-47197), and IFITM3 (Abgent AP1153a ...
• Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2021

  Quote: ... BCL-2 (Santa Cruz, 1:2000), ChAT (Cell Signalling ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-p-ERK1/2 (Santa Cruz Biotechnology ...
• MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

  Célia Guérin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (Santa Cruz #Sc-154), ERK1/2-Phospho (Cell Signaling #9101) ...
• Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice

  André A. Weber, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... AMPKα1/2 (Santa Cruz, sc-25792), CYP7A1 (Abcam ...
• Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

  Brandon Elliott, et al., bioRxiv - Physiology 2024

  Quote: ... polycystin 2 (1:100; Santa Cruz). Primary antibodies were detected with fluorescent secondary antibodies (Alexa Fluor 488 ...
• Capture of Human Neuromesodermal and Posterior Neural Tube Axial Stem Cells

  Dolunay Kelle, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 2 µM IWP2 (Santa Cruz). The cells were split using 1X TrypLE Express at a ratio of 1:20-1:40.
• A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer

  Maria Grześ, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Gli-2 (Santa Cruz sc-271786); c-Jun (Santa Cruz sc-74543) ...
• GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage

  Terezia Vcelkova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 2 μg GSE1 (515046, Santa Cruz), 30 μl of monoclonal HDAC1 (clone 10E2 ...
• Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumors

  Chuankai Chen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (Santa Cruz, sc-514302).
• Control of intestinal stemness and cell lineage by histone variant H2A.Z isoforms

  Jérémie Rispal, et al., bioRxiv - Physiology 2024

  Quote: ... Mucin 2 (sc-15334, Santa Cruz), Lysosyme (ab108508 ...