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5901 - 5950 of 8510 citations for 6 Chloro 2 3 diphenylimidazo 1 2 b pyridazine since 2019

• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... followed by immunoblotting using an anti-KRAS antibody (1:1000, WH0003845MI for G12D, Sigma-Aldrich; and 1:2000, F234 for G12V, Santa Cruz Biotechnology, Inc., Dallas, TX, USA). The immunoreactive bands were detected ...
• Bioengineering a plant NLR immune receptor with a robust binding interface towards a conserved fungal pathogen effector

  Rafał Zdrzałek, et al., bioRxiv - Plant Biology 2024

  Quote: ... membranes were incubated with appropriate antibodies diluted in blocking buffer (α-FLAG: Cohesion Biosciences, at 1:3000 dilution; α-Myc: Santa Cruz Biotechnology, at 1:5000 dilution) overnight ...
• CryoET shows cofilactin filaments inside the microtubule lumen

  Camilla Ventura Santos, et al., bioRxiv - Cell Biology 2023

  Quote: ... Membranes were incubated with primary antibodies at 4°C over-night or for 1 h at room temperature at the following dilutions: α-tubulin (sc-32293, Santa Cruz, 1:5000 in 5% milk, mouse), anti-cofilin (gift from Anna Marie Sokac ...
• Dopamine D1 receptor activation and cAMP/PKA signalling mediate Brd4 recruitment to chromatin to regulate gene expression in rat striatal neurons

  Jace Jones-Tabah, et al., bioRxiv - Neuroscience 2021

  Quote: ... Anti-cFos polyclonal (1:2000, catalogue #sc-52, Lot #C1010, Santa Cruz), anti-cFos monoclonal (1:5000 ...
• A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

  Marek M. Drozdz, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and cytochrome C (2CYTC-199; Santa Cruz, #sc-81752; dilution 1:50). Secondary antibodies used were donkey anti-mouse and donkey anti-rabbit conjugated to Alexa Fluor 488 or Alexa Fluor 647 (Thermo ...
• A subset of CB002 xanthine analogues bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

  Liz J. Hernández Borrero, et al., bioRxiv - Cancer Biology 2021

  Quote: ... The following antibodies were used: p53 (1:1000, #sc-126, Santa Cruz), p73 (1:1000 ...
• Pathway-based approach reveals differential sensitivity of glioblastoma to E2F1 inhibition

  Alvaro G. Alvarado, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and probed using the following antibodies: E2F1 (Santa Cruz Biotechnology, 1:500), CIP2A (Santa Cruz Biotechnology ...
• Primary myeloid cell proteomics and transcriptomics: importance of ß tubulin isotypes for osteoclast function

  David Guérit, et al., bioRxiv - Cell Biology 2020

  Quote: ... primary antibodies against pan ß tubulin (sc-398937 1:1000. Santa Cruz) and Gapdh (#2118 1:10.000 ...
• Htr6 and Sstr3 ciliary targeting relies on both IC3 loops and C-terminal tails

  Pablo Barbeito, et al., bioRxiv - Cell Biology 2020

  Quote: ... Goat polyclonal antibodies: γ-Tubulin (Santa Cruz, sc-7396, IF: 1:200). AlexaFluor (AF)-conjugated donkey secondary antibodies from Thermofisher (all used for IF at 1:10,000) ...
• Fine tuning of calcium constitutive entry by optogenetically-controlled membrane polarization: impact on cell migration

  C-A. Chapotte-Baldacci, et al., bioRxiv - Cell Biology 2020

  Quote: ... and a mouse anti-GAPDH antibody (1:1000, sc-32233, Santa Cruz). Horseradish peroxidase-conjugated goat anti-rabbit and goat anti-mouse antibodies (1:5000 ...
• Primary mammary organoid model of lactation and involution

  Jakub Sumbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... and mouse monoclonal anti-β-casein (Santa Cruz, sc-166530; 1:250). Corresponding secondary antibodies were used ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stained using anti-ASC (Santa Cruz, sc22514R, 4 μg.mL-1), Alexa594-goat anti rabbit antibodies (Invitrogen ...
• Embryonic hyperglycemia perturbs the development of specific retinal cell types, including photoreceptors

  Kayla F. Titialii-Torres, Ann C. Morris, bioRxiv - Developmental Biology 2021

  Quote: ... anti-PKCα (bipolar cells, mouse, 1:100, Santa Cruz Biotechnology, Dallas, TX), and anti-Prox1 (horizontal cells ...
• BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

  Alexandra M. Young, et al., bioRxiv - Cell Biology 2020

  Quote: Mouse anti–BAF (1:250; clone A11; sc-166324; Santa Cruz Biotechnology)
• Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus

  Shunya Yagi, et al., bioRxiv - Neuroscience 2020

  Quote: ... or 1:500 mouse anti-Sox2 (Santa Cruz Biotechnnology; Dallas, Texas USA), 0.3% Triton-X ...
• BRD9-containing non-canonical BAF complexes safeguard cell identity and prevent reprogramming

  Kenan Sevinç, et al., bioRxiv - Developmental Biology 2021

  Quote: ... at 1:1000 ratio and HDAC1 antibody (Santa Cruz, Catalog: sc-7872) at 1:500 ratio overnight at 40C ...
• Proteasome-mediated regulation of Cdhr1a by Siah1 modulates photoreceptor development and survival in zebrafish

  Warlen P. Piedade, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-PKCα (bipolar cells, mouse, 1:100, Santa Cruz Biotechnology, Dallas, TX), anti-Prox1 (horizontal cells ...
• Evolutionarily conserved regulation of embryonic fast-twitch skeletal muscle differentiation by Pbx factors

  Gist H. Farr III, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 1:100 rabbit polyclonal anti-Myf5 (IgGH+L, Santa Cruz, sc-302) and 1:100 monoclonal mouse anti-Pbx1b (IgG1 ...
• Wnt-dependent activation of ERK mediates repression of chondrocyte fate during calvarial development

  Beatriz Ibarra, Cody Machen, Radhika P. Atit, bioRxiv - Developmental Biology 2021

  Quote: ... Immunoblots were probed with anti-β-TUBULIN (1:400, Santa Cruz 9104) as a loading control where indicated ...
• The laminin-keratin link shields the nucleus from mechanical deformation and signalling

  Zanetta Kechagia, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-YAP1 YAP1 (63.7) 1:100 (Santa Cruz, Cat# sc-101199), rabbit anti-Cytokeratin 8 [EP1628Y] 1:200 (Abcam ...
• The laminin-keratin link shields the nucleus from mechanical deformation and signalling

  Zanetta Kechagia, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-Lamin A/C (E1) 1:100 (Santa Cruz, Cat# sc376248), rabbit anti-Tri-Methyl-Histone H3 (Lys27 ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-CDC45 (1/100; sc-55569 from Santa Cruz Biotechnology, RRID:AB_831146), rabbit anti-PCNA (1/500 ...
• Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

  Nuria Ferrandiz, et al., bioRxiv - Cell Biology 2022

  Quote: ... HRP conjugated mouse anti-β-actin (sc-47778, Santa Cruz, 1: 20000); rabbit anti-mCherry (ab183628 ...
• Myelin speeds cortical oscillations by consolidating phasic parvalbumin-mediated inhibition

  Mohit Dubey, et al., bioRxiv - Neuroscience 2021

  Quote: ... Sections were stained with primary mouse anti-MBP (1:300, Santa Cruz), rabbit anti-syt2 in 0.4% Triton-X and 2% NHS with PBS solution for 72 h ...
• Differential impact of Kv8.2 loss on rod and cone signaling and degeneration

  Shivangi M Inamdar, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Na/K-ATPase M7-PB-E9 at 1:1000 (Santa Cruz Biotechnology Cat# sc-58628 ...
• Substrate-induced clustering activates Trim-Away of pathogens and proteins

  Jingwei Zeng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-TRIM21 (D-12, Santa Cruz Biotechnology sc-25351; 1:500), rabbit anti-TRIM21 (D1O1D ...
• Chronic effects of short-term aerobic and anaerobic physical training on the ventral prostate of adult rats

  Rodrigo Miranda Ramos Borges, et al., bioRxiv - Molecular Biology 2021

  Quote: ... NOS2 (C-11): (dilution 1: 50, Santa Cruz Biotechnology, Inc.inc sc-7271), and anti-ED1 [MCA341R] (dilution 1 ...
• CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 plasmid retention function

  Apurva T. Prabhakar, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Casein kinase IIα (1AD9) 1:500 (Santa Cruz; catalog no. sc-12738), CKII alpha’ Antibody 1:1000 (Bethyl ...
• TENT4A non-canonical poly(A) polymerase regulates DNA-damage tolerance via multiple pathways which are mutated in endometrial cancer

  Umakanta Swain, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-PCNA (PC-10) (Santa Cruz, sc-56, dilution 1:1000); mouse anti-FLAG M2 (Sigma-Aldrich ...
• The C. elegans ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator

  Gwendolyn M. Beacham, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-PP1 (1:1000, Santa Cruz, clone E-9, sc-7482), and rat anti-HA directly conjugated to HRP (1:500 ...
• Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM1

  Max L.B. Grönloh, et al., bioRxiv - Immunology 2022

  Quote: ... ICAM-1 rabbit polyclonal antibody was purchased from Santa Cruz (SC-7891) (WB 1:1000) ...
• Electroporated recombinant proteins as tools for in vivo functional complementation, imaging, and chemical biology

  Amal Alex, et al., bioRxiv - Cell Biology 2019

  Quote: ... membranes were probed with anti-αSYN sc69977 (Santa Cruz, 1:100 dilution) and anti-Actin IgM (Merck Millipore ...
• Listeria monocytogenes exploits the MICOS complex subunit Mic10 to promote mitochondrial fragmentation and cellular infection

  Filipe Carvalho, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit polyclonal anti-Tom20 clone F-10 (1:200; Santa Cruz Biotechnology), and mouse monoclonal anti-FLAG clone M2 (1:100 ...
• Human PUM1 and PUM2 exhibit regulation of divergent mRNA targets in male germ cells

  Maciej Jerzy Smialek, et al., bioRxiv - Molecular Biology 2019

  Quote: ... and HRP-linked anti-goat (1:50000 Santa Cruz Biotechnology #sc-2020), as well as HRP-linked anti-rabbit (1:25000 Sigma Aldrich A0545) ...
• Human PUM1 and PUM2 exhibit regulation of divergent mRNA targets in male germ cells

  Maciej Jerzy Smialek, et al., bioRxiv - Molecular Biology 2019

  Quote: ... goat anti-PUM2 (1:250 Santa Cruz Biotechnology #K-14, sc-31535), rabbit anti-actin beta (ACTB ...
• Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

  Hebah Sindi, et al., bioRxiv - Cell Biology 2019

  Quote: ... and rabbit polyclonal anti-PCNA (1:500, Santa Cruz Biotechnology, sc-7907). Secondary antibodies were HRP-linked Goat Anti-Rabbit IgG (1:3000 ...
• Systematic Analysis of Targets of Pumilio (PUM)-Mediated mRNA Decay Identifies a Role of PUM1 in Regulating DNA Damage Response Pathway

  Toshimichi Yamada, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 1:100 dilution of anti-PCNA rabbit polyclonal antibody (Santa Cruz, #sc7907), 1:100 dilution of anti-UBE2A rabbit polyclonal antibody (Abcam ...
• Requirement of FLCN tumor suppressor gene for mTORC1-mediated inhibition of TFE3 transcriptional activity

  Hua Li, et al., bioRxiv - Cell Biology 2020

  Quote: ... Antibodies against Topoisomerase 1 alpha and ASAH1 were purchased from Santa Cruz. 14-3-3 antibody and active recombinant AMPK (α2β1γ1 ...
• NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection

  L. S. Tran, et al., bioRxiv - Immunology 2019

  Quote: ... mouse anti-human caspase-1 (0.1 μg/ml; sc56036; Santa Cruz Biotechnology), rabbit anti-Asc (1 μg/ml ...
• Duo-activation of PKA and PKG by PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against proteinopathy

  Hanming Zhang, et al., bioRxiv - Cell Biology 2019

  Quote: ... and immunodetected with anti-PDE1A (SC-50480, Santa Cruz biotechnology, 1:800), anti-GAPDH (G8795 ...
• A mutation in Hnrnph1 that decreases methamphetamine-induced reinforcement, reward, and dopamine release and increases synaptosomal hnRNP H and mitochondrial proteins

  Qiu T. Ruan, et al., bioRxiv - Neuroscience 2019

  Quote: ... or tyrosine hydroxylase (TH) (1:500, Rabbit polyclonal, Santa Cruz sc-14007) primary antibodies ...
• Antifibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis

  Guorong Li, et al., bioRxiv - Physiology 2020

  Quote: ... or fibronectin (FN; 1:50 dilution, mouse monoclonal, Santa Cruz, Dallas, Texas). The secondary antibodies were peroxidase-conjugated AnffiniPure Goat Anti-Rabbit or mouse IgG H&L (Alexa Fluor® 488 ...
• Resveratrol attenuates high-fat diet-induced obesity and the aging-related sarcopenia mitochondrial dysfunction in skeletal muscle

  Chyi-Huey Bai, Javad Alizargar, Jia-Ping Wu, bioRxiv - Animal Behavior and Cognition 2019

  Quote: ... or anti-mouse (1:1000) IgG secondary antibodies (Santa Cruz Lab, CA) for 1hr at room temperature ...
• Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

  Benjamin Gotte, et al., bioRxiv - Microbiology 2019

  Quote: ... goat anti-eIF3B (Santa Cruz Biotechnology N-20 sc-16377; 1:200), rabbit anti-eIF4A (Abcam ab31217 ...
• An aphid effector promotes barley susceptibility through suppression of defence gene expression

  Carmen Escudero-Martinez, et al., bioRxiv - Plant Biology 2019

  Quote: ... for 1 hour with anti-rabbit-HRP (Santa Cruz Biotechnology Inc, USA).
• Mammalian musculoskeletal regeneration is associated with reduced inflammatory cytokines and an influx of T cells

  Thomas R. Gawriluk, et al., bioRxiv - Immunology 2019

  Quote: ... incubated with secondary antibody (Santa Cruz Biotechnologies, Cat#sc-2030, 1:10,000), and visualized by chemiluminescence (Cat#RPN2235 ...
• Protein kinase Cε activation induces EHD-dependent degradation and downregulation of K_ATP channels: Implications for glucose stimulated insulin secretion

  Christopher J Cockcroft, et al., bioRxiv - Cell Biology 2020

  Quote: ... or mouse anti-Rme-1-4 (Santa Cruz Biotechnology, EHD (E-5), 0.8 μg/ml ...
• Alterations of redox and iron metabolism accompany development of HIV latency.

  Iart Luca Shytaj, et al., bioRxiv - Molecular Biology 2019

  Quote: ... or PML (sc/966x, 1:500; Santa Cruz Biotechnology, Dallas, TX, USA) for 1-2 hr at RT ...
• Thymosin β4 mediates vascular protection via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

  Sonali Munshaw, et al., bioRxiv - Cell Biology 2019

  Quote: ... Rabbit anti-phospho-LRP1 (Tyr4507) (1:100; Santa Cruz Biotechnology, sc-33049); Rabbit anti-phospho-PDGFRβ (Tyr1021 ...
• Thymosin β4 preserves vascular smooth muscle phenotype in atherosclerosis via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

  Sonali Munshaw, et al., bioRxiv - Pathology 2021

  Quote: ... Rabbit anti-phospho-LRP1 (Tyr4507) (1:100; Santa Cruz Biotechnology, sc-33049); Rabbit anti-phospho-PDGFRβ (Tyr1021 ...