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451 - 500 of 771 citations for 7 bromoquinolin 2 amine since 2019

• A Sequence determinant in 3’UTR of mRNAs for Nuclear Retention by Paraspeckles

  Audrey Jacq, et al., bioRxiv - Molecular Biology 2020

  Quote: ... activating transcription factor 2 (ATF2) (anti-ATF2, sc-187, Santa Cruz Biotechnology, Heidelberg, Germany) on the one hand and a cytoplasmic protein ...
• UNC-10/SYD-2 complex is sufficient to link kinesin-3 to RAB-3 containing synaptic vesicles in the absence of the motor’s PH domain

  Prerana Bhan, et al., bioRxiv - Cell Biology 2020

  Quote: ... Primary goat (N-terminal) anti-SYD-2 antibody (cL-19 #sc-15655, Santa Cruz) was incubated at 4°C for 14 hours at 1/500 dilutions ...
• Synergic action of Vitamin D₃ and 17β-estradiol on behavioral impairments induced by unpredictable mild stress in the adult ovariectomized female rats

  Denis Baranenko, et al., bioRxiv - Animal Behavior and Cognition 2019

  Quote: ... monoclonal antibodies for 2 h and secondary antirabbit antibodies (1:5000; Santa Cruz, USA) conjugated to horseradish peroxidase for BDNF for 1 h ...
• Functionalized Biomimetic Hydrogels Enhance Salivary Stem/Progenitor Cell Organization

  Mariane Martinez, et al., bioRxiv - Bioengineering 2021

  Quote: ... N-(2-Hydroxyethyl)piperazine-N-(4-butanesulfonic acid) (HEPBS) was purchased from Santa Cruz Biotechnology ...
• Stimulus-specific processing of the plasma membrane receptor-like kinase FERONIA in Arabidopsis thaliana

  Cassidy S. Cornblatt, et al., bioRxiv - Plant Biology 2021

  Quote: ... Antibody dilutions used were 1:500 for α-GFP (B-2, Santa Cruz Biotechnology), 1:2500 for α-calnexin (CNX1/2 ...
• Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

  Golam T. Saffi, et al., bioRxiv - Cell Biology 2021

  Quote: ... and goat polyclonal antibody against dynamin 2 (1:1000, sc-6400, Santa Cruz Biotechnology). Secondary antibodies were raised in donkey (Bethyl ...
• Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via PDH regulation

  Takeshi Ikizawa, et al., bioRxiv - Cell Biology 2022

  Quote: ... rat monoclonal anti-α-tubulin antibody (YL1/2: Santa Cruz Biotechnology, Cat#sc-53029), mouse monoclonal anti-actin antibody (AC-40 ...
• The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

  Iart Luca Shytaj, et al., bioRxiv - Microbiology 2021

  Quote: ... cytotoxicity or inhibition of SARS-CoV-2 replication: cobicistat (#sc-500831; Santa Cruz Biotechnology), remdesivir (#S8932 ...
• Novel regulation of the transcription factor ZHX2 by N-terminal methylation

  Meghan M. Conner, et al., bioRxiv - Biochemistry 2021

  Quote: ... mouse anti-ZHX2 (D-2) (1:1000; sc-393399, Santa Cruz Antibodies, Dallas, TX), rabbit anti-CYP26A1 (1:1000 ...
• H₂S Prodrug, SG-1002, Protects Against Myocardial Oxidative Damage and Hypertrophy via Induction of Cystathionine β-Synthase and Antioxidant Proteins

  Rahib K. Islam, et al., bioRxiv - Cell Biology 2021

  Quote: The polyclonal antibody for GPx-1/2 (sc-30147) was purchased from Santa Cruz Biotechnology ...
• The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A)-translation

  Andrea Hildebrandt, et al., bioRxiv - Molecular Biology 2019

  Quote: The following antibodies were used: anti-GFP (B-2 clone; Santa Cruz; sc-9996), anti-MKRN1 (Bethyl Laboratories ...
• Arpin regulates migration persistence by interacting with both tankyrases and the Arp2/3 complex

  Gleb Simanov, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following commercial antibodies were used: TNKS1/2 pAb (H-350, Santa Cruz Biotechnology), ArpC2 pAb (Millipore) ...
• The helper NLR immune protein NRC3 mediates the hypersensitive cell death caused by the cell-surface receptor Cf-4

  Jiorgos Kourelis, et al., bioRxiv - Plant Biology 2021

  Quote: ... or mouse monoclonal anti-GFP antibody conjugated to HRP (B-2, Santa Cruz Biotech) in a 1:5000 dilution ...
• Nucleotide binding is the critical regulator of ABCG2 conformational transitions

  Zsuzsanna Gyöngy, et al., bioRxiv - Biochemistry 2022

  Quote: ... while actin was labeled with the C-2 mouse mAb (both from Santa Cruz Biotechnology Inc. ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-LIMK-2 monoclonal antibody (1:100 dilution, sc-365414, Santa Cruz Biotechnology), mouse anti-F-actin monoclonal antibody (1:500 dilution ...
• CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair

  Dalia Hassan, Jichao Chen, bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-NK homeobox 2-1 (NKX2-1, 1:1000, sc-13040, Santa Cruz), rabbit anti-pro-surfactant protein C (SFTPC ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... Erk1/2 (1:2000 each, rabbit, Santa Cruz Biotechnology C-16 and C-14), pT320-pp1 (1:1000 for the detection of the endogenous protein ...
• An integrated mechanistic and data-driven computational model predicts cell responses to high- and low-affinity EGFR ligands

  Paul J. Myers, Sung Hyun Lee, Matthew J. Lazzara, bioRxiv - Systems Biology 2023

  Quote: ... and ERK 1/2 (Alexa Fluor 546-conjugated; Santa Cruz sc-514302, 1:200) diluted in IBB ...
• MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

  Zhihui Liu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Two different MYCN antibodies (antibody 1, Santa Cruz, sc-53993; antibody 2, Abcam, ab16898) (4 µg) ...
• Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

  Elena Marchesan, et al., bioRxiv - Cell Biology 2023

  Quote: ... 5 mg of lysate was incubated with Parkin antibody (2 μg; Santa Cruz 32282) or with Calcineurin antibody (2 μg ...
• Red-purple Andean potato polyphenols have an anti-neuroblastoma effect in vitro via apoptosis through mitochondria

  María Ximena Silveyra, Adriana Balbina Andreu, bioRxiv - Cancer Biology 2023

  Quote: ... We incubated the membrane with an anti-Bcl-2 (sc-7382, Santa Cruz Biotechnology) or anti-Caspase-3 (sc-56053 ...
• The CUL4-DDB1-DCAF1 E3 ubiquitin ligase complex regulates PLK4 protein levels to prevent premature centriole duplication

  Josina Grossmann, et al., bioRxiv - Cell Biology 2023

  Quote: ... cells were treated with 2 mM thymidine (Santa Cruz Biotechnology, catalog no.: sc-296542A) for 18 h ...
• The Wolfram-like variant WFS1^E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice

  Simone Patergnani, et al., bioRxiv - Neuroscience 2023

  Quote: ... cells were reconstituted for 2 hours with 5 µM coelenterazine wt (Santa Cruz Biotechnology) in DMEM high glucose supplemented of 0.1% FBS and transferred to the perfusion chamber ...
• CCDC32 stabilizes clathrin-coated pits and drives their invagination

  Ziyan Yang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Anti-α-Adaptin 1/2 Antibody (C-8) (Santa Cruz Biotechnology, Catalog #sc-17771) was used in WB to detect AP2 enrichments.
• Deamidated TPI is an efficacious target for cell-selective therapy in triple-negative breast cancer

  Sergio Enríquez-Flores, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Bax (B-9) and β-Actin (C-2) (Santa Cruz Biotechnology, Santa Cruz, CA, USA) at a dilution of 1:1000 in 0.1% TBS-Tween-20 and 1% BSA and washed three times with the same buffer ...
• Deamidated TPI is an efficacious target for cell-selective therapy in triple-negative breast cancer

  Sergio Enríquez-Flores, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Bax (B-9) and β-Actin (C-2) (Santa Cruz Biotechnology, Santa Cruz, CA, USA) at a dilution of 1:1000 in 0.1% TBS-Tween-20 and 1% BSA and washed three times with the same buffer ...
• Quantification of extracellular vesicles with unaltered surface membranes using an internalized oligonucleotide tracer and droplet digital PCR applied to modeling of in vivo kinetics

  Thomas De Luca, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-GM130 (clone B-10, 2 μg/mL, cat. no. sc-55591, Santa Cruz Biotechnology), anti α-actinin (clone H-2 ...
• SAMHD1 regulates human papillomavirus 16 induced cell proliferation and viral replication during differentiation of oral keratinocytes

  Claire D. James, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Fluorescent in situ hybridization (FISH ...
• Human PUM1 and PUM2 exhibit regulation of divergent mRNA targets in male germ cells

  Maciej Jerzy Smialek, et al., bioRxiv - Molecular Biology 2019

  Quote: TCam-2 cells were transfected with siRNA using PUM1 siRNA (sc-62912 Santa Cruz Biotechnology), PUM2 siRNA (sc-44773 ...
• Astrocytes express DMT1 and transferrin receptors, which transport iron thus activating Ca²⁺ signalling: possible role in neuroprotection against iron overload?

  Maosheng Xia, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Na+/K+-ATPase alpha1/2 antibody and the secondary antibodies were bought from Santa Cruz Biotechnology (Santa Cruz ...
• VHL ligand binding increases intracellular level of VHL

  Julianty Frost, Sonia Rocha, Alessio Ciulli, bioRxiv - Biochemistry 2021

  Quote: ... Protein lysates were incubated with 2 μg of HIF-1α antibody (Santa Cruz; sc-53546) or 2 μg of mouse IgG control antibody (Sigma ...
• Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury

  Ayşe N. Ozantürk, et al., bioRxiv - Immunology 2022

  Quote: ... Cells were blocked by adding 2% bovine serum albumin (9048-46-8, Santa Cruz Biotechnology) in PBS for 30 min at RT followed by washing twice with PBS ...
• Werner syndrome protein (WRN) regulates cell proliferation and the human papillomavirus 16 life cycle during epithelial differentiation

  Claire D. James, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Fluorescent in situ hybridization (FISH ...
• Myelination deficits in the auditory brainstem of a mouse model of Fragile X Syndrome, a possible mechanism for auditory phenotypes

  Alexandra Lucas, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse Sox-10 (A-2) (Santa Cruz, Dallas, TX, USA; sc-365692, 1:500) diluted in blocking solution with 1% NGS and incubated overnight (Table 1) ...
• Human colon-on-a-chip enables continuous in vitro analysis of colon mucus layer accumulation and physiology

  Alexandra Sontheimer-Phelps, et al., bioRxiv - Cell Biology 2019

  Quote: Panel 1 (2% PFA fixation): anti-MUC2 (H-9, sc-515106, Santa Cruz, 1:100), anti-mouse-IgG2b-546 (A-21143 ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-phospho-AKT1/2/3 (Ser 473) (anti-rabbit, 1:1000; sc-33437, Santa Cruz), anti-phospho-IKKα/β (Ser176/180)(16A6 ...
• Early detection of SARS-CoV-2 in circulating immune cells in a mouse model

  Tingting Geng, et al., bioRxiv - Microbiology 2021

  Quote: ... hACE2 (Mouse-anti-Human ACE-2, Cat# sc-390851, clone E-11, Santa Cruz Biotechnology) indirectly labeled with goat-anti-mouse Alexa Fluor 594 ...
• Regulation of DNA damage response by trimeric G-protein Signaling

  Amer Ali Abd El-Hafeez, et al., bioRxiv - Cancer Biology 2021

  Quote: Pooled guide RNA plasmids (commercially obtained from Santa Cruz Biotechnology; Cat# sc-402236-KO-2) were used ...
• Antibodies control metabolism by regulating insulin homeostasis

  Timm Amendt, et al., bioRxiv - Immunology 2021

  Quote: ... Chemical thiol-crosslinking was done using 1,2-Phenylen-bis-maleimide (Santa Cruz, 13118-04-2) at 100 μg/mL for 48 h at room temperature (dark ...
• An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish

  Dianne Lumaquin, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cells were fixed with 2% paraformaldehyde (Santa Cruz Biotechnology, Santa Cruz, USA, Catalog #sc-281692) for 45 minutes ...
• Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection

  Ruobing Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-MUC5B antibody (mouse monoclonal, Santa Cruz Biotechnology, 1:500 cat#SC-39395-2). The anti-SARS-CoV nucleoprotein (N ...
• The Cytomegalovirus M35 Protein Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes by Direct Promoter Binding

  Hella Schwanke, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HRP-coupled GFP-antibody (clone B-2, #sc-9996 HRP) was purchased from Santa Cruz Biotechnology (Heidelberg ...
• Leveraging co-evolutionary insights and AI-based structural modeling to unravel receptor-peptide ligand-binding mechanisms

  Simon Snoeck, et al., bioRxiv - Biochemistry 2024

  Quote: ... prior to incubation with α-GFP (B-2) HRP (Santa Cruz 9996 HRP, 1:1500). Western blots were imaged with a Bio-Rad ChemiDoc and Image Lab Touch Software (v2.2.0.08) ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cellular DNA was stained with 4’,6-diamidino-2-phenylindole (DAPI, Santa Cruz sc-3598). Coverslips were mounted onto slides using Vectashield medium (ThermoFisher ...
• Modeling Mechanical Activation of Macrophages During Pulmonary Fibrogenesis for Targeted Anti-Fibrosis Therapy

  Ying Xu, et al., bioRxiv - Bioengineering 2023

  Quote: ... and Rho associated coiled-coil containing protein kinase 2 (Santa Cruz, sc-398519, 1:100). These antibodies were labeled with fluorophore-conjugated ...
• Structure and activity of botulinum neurotoxin X

  Markel Martínez-Carranza, et al., bioRxiv - Biochemistry 2023

  Quote: ... Primary antibodies used were against VAMP-2 (custom made) and VAMP4 (Santa Cruz sc-365332). The secondary antibodies were HRP-conjugated ant-rabbit IgG (Sigma A6154 ...
• Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia

  Laura R. Nementzik, et al., bioRxiv - Neuroscience 2023

  Quote: ... The ubiquilin 2 antibody used here (mouse monoclonal anti-ubiquilin IgG2a, Santa Cruz #SC-100612) has been used by us previously for the detection of neuropathological aggregates [18 ...
• Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells

  Stefan Klimaj, et al., bioRxiv - Microbiology 2024

  Quote: ... or Mx 1/2/3 1:400 in PBS (Santa Cruz Biotechnology, sc-166412 AF488). Representative images were acquired via the EVOS FL Auto imaging system (Thermo Fisher Scientific).
• Production of human translation-competent lysates using dual centrifugation

  Lukas-Adrian Gurzeler, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Puromycin control reactions contained 320 μg/ml puromycin (Santa Cruz Biotechnology, Cat. No. 58-58-2). Before adding reporter mRNAs ...
• Intermediary role of lung alveolar type 1 cells in epithelial repair upon Sendai virus infection

  Belinda J Hernandez, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-sex determining region Y-box 2 (SOX2, 1:250, Santa Cruz Biotechnology, SC-17320), rat anti-antigen identified by monoclonal antibody Ki 67 (Ki67 ...