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1901 - 1950 of 6989 citations for 8 CYANO IMIDAZO 1 2 A PYRIDINE 2 CARBOXYLIC ACID ETHYL ESTER since 2019

• Endothelial-derived sphingolipids are required for vascular development and systemic lipid homeostasis

  Andrew Kuo, et al., bioRxiv - Developmental Biology 2022

  Quote: ... eNOS (BD Biosystem; 1:2000) β-actin (Sigma ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... CD31 (BD, AF3628, 1:100), GFP (Cell signaling ...
• Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert tumor microenvironment and confers resistance to immunotherapy

  Juan Yan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... BV510_CD4 (1:200, BD, #563106), PE_B220 (1:400 ...
• Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state

  Jean-Christophe Beltra, et al., bioRxiv - Immunology 2022

  Quote: ... GolgiPlug (1/500; BD bioscience) and gp33-41 peptide (NIH ...
• TET1 potentiates human iPS cell reprogramming by rectifying extraembryonic gene noises

  Makoto Motono, et al., bioRxiv - Cell Biology 2022

  Quote: ... PAX6 (1:500; BD Biosciences), MAP2 (1:2000 ...
• The Crk adapter protein is essential for Drosophila embryogenesis, where it regulates multiple actin-dependent morphogenic events

  Andrew J. Spracklen, et al., bioRxiv - Cell Biology 2019

  Quote: ... DR (1:500; BD Biosciences), and AF647 wheat germ agglutinin (1:1,000 ...
• The transcription factor E2A drives neural differentiation in pluripotent cells

  Chandrika Rao, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Sox1(1:200; BD Pharmigen), Sox2 (1:200 ...
• Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole

  Ila S. Anand, Won Young Choi, Ralph R. Isberg, bioRxiv - Microbiology 2019

  Quote: ... EEA1 (BD Biosciences, 1:500), Rab11FIP1 (Cell Signaling ...
• Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice

  Florence Njau, et al., bioRxiv - Cell Biology 2019

  Quote: ... ZO-1 (BD Transduction Laboratories), Vinculin (Chemicon) ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Bub3 (BD 811730, 1:500), Cep131 / AZI-1 (Bethyl A301-415A ...
• Propranolol reduces sarcoma growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

  Klaire Yixin Fjæstad, et al., bioRxiv - Cancer Biology 2021

  Quote: ... GolgiPlug (1/1000, BD Biosciences) was added to the mixed culture and incubated for an additional 4 hours ...
• Extracellular electron transfer increases fermentation in lactic acid bacteria via a hybrid metabolism

  Sara Tejedor-Sanz, et al., bioRxiv - Microbiology 2021

  Quote: ... 1 g/L NH4Cl) (BD) for the counter electrode chamber ...
• Force-independent interactions of talin and vinculin govern integrin-mediated mechanotransduction

  Paul Atherton, et al., bioRxiv - Cell Biology 2019

  Quote: ... 9EG7 (BD Biosciences, 1:200), anti-phosphotyrosine (4G10 ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Opa1 (BD, 1/1000). Western blot quantification was performed using the Fiji software47.
• Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals

  Xinghong Ma, et al., bioRxiv - Evolutionary Biology 2020

  Quote: ... 1% ITS+ Premix (354352, BD), 1% ABAM ...
• Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

  Julia Noack, et al., bioRxiv - Cell Biology 2020

  Quote: ... TOM20 1:200 (BD Biosciences); secondary antibodies ...
• Cell size is a determinant of stem cell potential during aging

  Jette Lengefeld, et al., bioRxiv - Cell Biology 2020

  Quote: ... myeloid markers Gr-1 (BD Biosciences Cat#562709 ...
• Human spinal cord differentiation proceeds rapidly in vitro and only initially maintains differentiation pace in a heterologous environment

  Alwyn Dady, et al., bioRxiv - Developmental Biology 2021

  Quote: ... SNAI2 (1/200; BD Biosciences), SOX10 (1/200 ...
• Maternal vgll4a promotes blastoderm cohesion enabling yap1-mediated mechano-transduction during zebrafish epiboly

  Carlos Camacho-Macorra, et al., bioRxiv - Developmental Biology 2020

  Quote: ... β-catenin (1:300, BD Bioscience) and E-cadherin (1:300 ...
• Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

  Raquel Furtado, et al., bioRxiv - Immunology 2020

  Quote: ... Golgi Stop (BD, 1/1000), PMA (Fisher ...
• Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

  Raquel Furtado, et al., bioRxiv - Immunology 2020

  Quote: ... Golgi Plug (BD, 1/1000), Golgi Stop (BD ...
• The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance

  Saleh F. Alquethamy, et al., bioRxiv - Microbiology 2020

  Quote: ... containing 1% tryptone (BD Bacto), 0.5% yeast extract (BD Bacto ...
• Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

  Dan Corral, et al., bioRxiv - Immunology 2021

  Quote: ... TCF-1 (S33-966, BD), Arg1 (A1exF5 ...
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... GM130 (BD, 610822, 1:100), and KI67 (Cell signaling ...
• An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

  Mirja Harms, et al., bioRxiv - Immunology 2020

  Quote: ... DAPI (BD Bioscience, 1:500). Live leukocytes were identified as CD45+DAPI- cells then differentiated into T cells (CD11blowCD19-CD3+) ...
• HES1 is a Critical Mediator of the SHH-GLI3 Axis in Regulating Digit Number

  Deepika Sharma, et al., bioRxiv - Developmental Biology 2020

  Quote: ... P27 (1:1000; BD Biosciences), CCND1 (1:1000 ...
• Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in SCA1

  Kimberly Luttik, et al., bioRxiv - Neuroscience 2021

  Quote: ... β-catenin (BD 610154, 1:20,000), and GST (Sigma G7781 ...
• Fibronectin-mediated inflammatory signaling through integrin α5 in vascular remodeling

  Madhusudhan Budatha, et al., bioRxiv - Physiology 2021

  Quote: ... CD45 (1:200, BD Biosciences); Sections were washed 3 times with PBS and incubated with Alexa flour 598-conjugated donkey anti rabbit or rat secondary antibody for 1 hour at room temperature ...
• High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses

  Sandy S. Burkart, et al., bioRxiv - Immunology 2022

  Quote: ... STAT1 (BD, 610115, 1:1000), or STAT2 (Santa Cruz ...
• Microcosm cultures of a complex synthetic community reveal ecology and genetics of gut microbial organization

  Xiaofan Jin, et al., bioRxiv - Microbiology 2022

  Quote: ... and 1% agar (BD 214030) solution solidified onto K1 biofilm carriers (Evolution Aqua MEDIAK1) ...
• Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

  Ann-Kathrin Mattes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or LFA-1 (BD, 559875) antibodies or respective isotype control antibodies where indicated and PE-CMV tetramer (MBL International ...
• Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

  Ann-Kathrin Mattes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and ICAM-1 (BD, 559771) antibodies or respective isotype control antibodies where indicated ...
• Characterization of Three Variants of SARS-CoV-2 in vivo Shows Host-Dependent Pathogenicity in Hamsters

  Gabriela Toomer, et al., bioRxiv - Microbiology 2022

  Quote: ... GolgiPlug (1 μL/mL, BD Biosciences Cat ...
• hnRNP R is a regulator of stress granule formation

  Changhe Ji, bioRxiv - Neuroscience 2022

  Quote: ... TIAR (1:500, BD,610352) in 2xSSC + 0.01% triton-X-100 and incubate for overnight at 4C ...
• The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation and Improves Autism-like Behavior in Zebrafish

  Golam M. Uddin, et al., bioRxiv - Molecular Biology 2022

  Quote: ... OPA1 (BD Biosciences; 1:1000); MFN1 (Cat# 3455S ...
• High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen

  Paul Ogongo, et al., bioRxiv - Immunology 2024

  Quote: ... 1:80 (all BD Biosciences)) diluted in Brilliant Violet buffer (BD ...
• Efficient enzyme-free isolation of brain-derived extracellular vesicles

  A. Matamoros-Angles, et al., bioRxiv - Neuroscience 2024

  Quote: ... Flotillin-1 (#610820, BD Biosciences), Flotillin-2 (#ab96507 ...
• Cytotoxic chemotherapy potentiates the immune response and efficacy of combination CXCR4/PD-1 inhibition in models of pancreatic ductal adenocarcinoma

  Alexander G. Raufi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Golgi-Plug (1:1000, BD) and Golgi-Stop (1:1500 ...
• Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

  Luciano Santollani, et al., bioRxiv - Immunology 2024

  Quote: ... CD44 (IM7, BD, 1:100), CD45.2 (BD ...
• Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

  Luciano Santollani, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (GK1.5, BD, 1:100), CD8 (53-6.7 ...
• Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity- Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies

  Lea Zillich, et al., bioRxiv - Neuroscience 2024

  Quote: ... N-CAD (1:500, BD), p-VIM (1:500 ...
• Pooled screening for CAR function identifies novel IL13Rα2-targeted CARs for treatment of glioblastoma

  Khloe S. Gordon, et al., bioRxiv - Immunology 2024

  Quote: ... anti-PD-1 (cloneEH12.1, BD) and fixable viability dye eFluor 455UV (eBioscience ...
• Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL

  Caroline Mitiká Watanabe, et al., bioRxiv - Cancer Biology 2024

  Quote: ... DNAM-1 (clone 11A8,BD), NKp30 (clone 210845 ...
• Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL

  Caroline Mitiká Watanabe, et al., bioRxiv - Cancer Biology 2024

  Quote: ... - CD57 (clone NK-1, BD), -TRAIL (clone RIK-2 ...
• PIKfyve controls dendritic cell function and tumor immunity

  Jae Eun Choi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TIM-1 (BD Biosciences: 5D12), PD-1/CD279 (BD Biosciences ...
• An Immunological Synapse Formation Between T Regulatory Cells and Cancer-Associated Fibroblasts Promotes Tumor Development

  Athina Varveri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and Brefeldin (1/1000) (BD) for 6 h at 37°C and 5% CO2 ...
• Tissue microenvironment dictates the state of human induced pluripotent stem cell-derived endothelial cells of distinct developmental origin in 3D cardiac microtissues

  Xu Cao, et al., bioRxiv - Developmental Biology 2022

  Quote: ... CD140a (1:20, BD Bioscience) were added for 1 hr at 4°C ...
• EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry

  Haitao Luan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Caveolain-1 (#610057) from BD Biosciences ...
• Chronic Changes In Oligodendrocyte Sub-Populations After Middle Cerebral Artery Occlusion in Neonatal Mice

  Alexandra P. Frazier, et al., bioRxiv - Neuroscience 2023

  Quote: ... BV421-CD45 1:500 (BD Biosciences ...
• Intracellular pH dynamics regulates intestinal stem cell lineage specification

  Yi Liu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... CD24 (BD, 553262, 1:250), and Live/Dead (Invitrogen ...