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4951 - 5000 of 8884 citations for 7 Chloro 3 methyl 3H 1 2 3 triazolo 4 5 d pyrimidine since 2019

• Lamin B Receptor Upregulation in Metastatic Melanoma Causes Cholesterol-Mediated Nuclear Envelope Fragility

  Michelle A. Baird, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lap2 (1:1000, BD Transduction Laboratories 611000), Mab414 (1:1000 ...
• Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

  Alexander J. Nelson, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (1:500, FITC, clone H129.19, BD), IgD (1:250 ...
• A multi-track landscape of haematopoiesis informed by cellular barcoding and agent-based modelling

  Dawn S. Lin, et al., bioRxiv - Immunology 2024

  Quote: ... CD11b-BB700 (BD, M1/70, 1:600), IL7Ra-biotin (In house ...
• Nitrosation of CD36 regulates endothelial function and serum lipids

  Melissa A. Luse, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and eNOS (BD transduction: 610297 1:1000). Membranes were washed and incubated in LiCOR IR Dye secondary antibodies (1:10,000 ...
• Mar1, an HMG-box protein, regulates n-alkane adsorption and cell morphology of the dimorphic yeast Yarrowia lipolytica

  Chiaki Kimura-Ishimaru, et al., bioRxiv - Microbiology 2024

  Quote: ... 1% Yeast extract (Becton, Dickinson and Company), and 2% glucose] or minimal medium described below ...
• Recapitulating memory B cell responses in a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies

  Raphaël Jeger-Madiot, et al., bioRxiv - Immunology 2024

  Quote: ... and 1:20 Fc Block (BD biosciences). The following primary antibodies were used ...
• Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

  Rebecca Warfvinge, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 1/100 7AAD (Hyclone, 559925, BD Bioscience). Two populations (Lin−CD34+ and Lin−CD34+CD38−/low ...
• Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides

  James H. Schofield, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Tim23 (BD Biosciences; no. 611222 (1:2000), Tom20 (CST ...
• The Escherichia coli TolC efflux pump protein is immunogenic and elicits protective antibodies

  TO Silva, et al., bioRxiv - Immunology 2023

  Quote: ... BV421 IgG1 at 1/25 (BD HorizonTM), APC CD38 at 1/300 (Thermo) ...
• Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity

  Yue Hu, et al., bioRxiv - Immunology 2023

  Quote: ... PD-1-Alexa flour 647 (BD, 566851), IL2-BV711 (BD #563946) ...
• Voltage-gated T-type calcium channel blockers reduce apoptotic body mediated SARS-CoV-2 cell-to-cell spread and subsequent cytokine storm

  Thanh Kha Phan, et al., bioRxiv - Cell Biology 2023

  Quote: ... in 1× A5 binding buffer (BD Biosciences) at room temperature for 10 minutes ...
• Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent anti-PD-L1- and anti-NKG2A-based adjuvant immunotherapy

  Emmanuel C Patin, et al., bioRxiv - Immunology 2023

  Quote: ... with 1 mg of BrdU (BD Biosciences) 12 hours before tumour harvest.
• Galectin-9 regulates dendritic cell contractility and migration via RhoA

  Guus Franken, et al., bioRxiv - Immunology 2023

  Quote: ... CD11c-APC (1:50 559877, BD Biosciences) and CD1c-PE (1:50 ...
• Development of MHC Class I Blocking Peptides to Target Metabolic Dysfunction-Associated Steatohepatitis CD8⁺ T Cell Activation

  Victoria Adams, et al., bioRxiv - Immunology 2024

  Quote: ... TCRb (APC-Cy7, 1:200; BD Biosciences), CD44 (A700 ...
• LRRK2 Kinase Activity Regulates Parkinson’s Disease-Relevant Lipids at the Lysosome

  Michael T. Maloney, et al., bioRxiv - Neuroscience 2022

  Quote: ... CD11b-BV421 (BD Biosciences 562605, 1:100), CD31-PerCP Cy5.5 (BD Biosciences #562861 ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Pax6 (mouse; 1:1000; BD Biosciences), anti-Rx (guinea pig ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Ki67 (mouse; 1:500; BD Biosciences), anti-Aqp1 (Aquaporin1 ...
• Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

  Kenji Watari, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-CtBP2 (mouse; 1:500; BD Biosciences), anti-PKCalpha (goat ...
• AAV-mediated Expression of a Novel Conformational Anti-Aggregated α-Synuclein Antibody Prolongs Survival in a Genetic Model of α-Synucleinopathies

  Matthias Düchs, et al., bioRxiv - Neuroscience 2022

  Quote: ... Syn-1 stainings (clone 42, BD Biosciences) were done at a dilution of 1:1000 ...
• Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

  Alba Grifoni, et al., bioRxiv - Immunology 2022

  Quote: ... CD14 V500 (1:50, BD, Cat# 561391), CD19 V500 (1:50 ...
• In vivo Safety and Immunoactivity of Oncolytic Jurona Virus in Hepatocellular Carcinoma: A Comprehensive Proteogenomic Analysis

  Yuguo Zhang, et al., bioRxiv - Immunology 2022

  Quote: ... PD-1-PE (Cat. # 551892; BD Biosciences), Ki67*-BV605 (Cat ...
• Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons

  Jacob W. Adelman, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Ki67 (1:500; BD Biosciences), rabbit anti-VGLUT2 (1:500 ...
• Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15

  Uddipta Biswas, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and IdU (1:100; BD Biosciences; 347580), and for 1 h with secondary antibodies anti-mouse Alexa Fluor 488 (Invitrogen ...
• Salmonella infection induces the reorganisation of follicular dendritic cell networks concomitant with the failure to generate germinal centres

  Edith Marcial-Juárez, et al., bioRxiv - Immunology 2022

  Quote: ... anti-IgD (11-26C.1; BD Bioscience), anti-follicular dendritic cell (FDC-M1 ...
• Salmonella infection induces the reorganisation of follicular dendritic cell networks concomitant with the failure to generate germinal centres

  Edith Marcial-Juárez, et al., bioRxiv - Immunology 2022

  Quote: ... anti-MadCAM-1 (MECA-367; BD Bioscience) and anti-CD21/35 (7E9 ...
• Sterile triggers drive joint inflammation in TNF and IL-1β dependent mouse arthritis models

  Alexandra Thiran, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-CD8 V500 (BD; 1/100). Thereafter ...
• Sterile triggers drive joint inflammation in TNF and IL-1β dependent mouse arthritis models

  Alexandra Thiran, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Siglec F BUV395 (BD; 1/200), anti-CD11b BV506 (BD ...
• The protooncogene Ski regulates the neuron-glia switch during development of the mammalian cerebral cortex

  Alice Grison, et al., bioRxiv - Systems Biology 2022

  Quote: ... mouse βCat (1:100, BD TransLab 610153). Sections were washed in PBS and incubated for 2 hours at room temperature with the appropriate secondary antibodies in blocking solution ...
• The bioactive dietary polyphenol preparation alleviates depression and anxiety-like behaviors by modulating the regional heterogeneity of microglia morphology

  Eun-Jeong Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD11b-PE Cy7 (1:1000, BD biosciences) for 1 hr on ice ...
• Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model

  Claire E. Otero, et al., bioRxiv - Immunology 2023

  Quote: ... Brefeldin A (GolgiPlug, 1:1000, BD Biosciences), monensin (GolgiStop ...
• Recruitment of PI4KIIIβ to the Golgi by ACBD3 is dependent on an upstream pathway of a SNARE complex and golgins

  Danièle Stalder, Igor Yakunin, David C. Gershlick, bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-GM130 (BD 610822, 1:200), mouse anti-PI4KIIIβ (BD Bioscience ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... UFD1 (611642, BD Biosciences, mouse, 1:1000); Ubiquitin (43124S ...
• Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

  Ali Rashidfarrokhi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Golgi Plug (BD Biosciences 55029, 1:1000), and Golgi Stop (BD biosciences 555029 ...
• Phosphoprotein dynamics of interacting tumor and T cells by HySic

  Sofía Ibáñez-Molero, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IFN-y-APC (1:100, BD, 554702).
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CD279 (BD, #562516, diluted 1:40), anti-TIM-3 (BD ...
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-BTLA (BD, #564800, diluted 1:60). After staining ...
• Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

  Ray Pillai, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Golgi Plug (BD Biosciences 55029, 1:1000), and Golgi Stop (BD biosciences 555029 ...
• Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

  Chima V. Maduka, et al., bioRxiv - Bioengineering 2023

  Quote: ... BUV615 CD19 (1:80, BD Bioscience, 751213), PacBlue Ly6G (1:250 ...
• BECLIN1 is essential for intestinal homeostasis

  Sharon Tran, et al., bioRxiv - Cell Biology 2023

  Quote: ... and CD19 (1:300, BD Biosciences, 563333) for total IEL analysis ...
• BECLIN1 is essential for intestinal homeostasis

  Sharon Tran, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CD45.2 (1:200, BD Biosciences, 741957), CD3ε (1:200 ...
• Spatiotemporal development of the human T follicular helper cell response to Influenza vaccination

  Stefan A Schattgen, et al., bioRxiv - Immunology 2023

  Quote: ... CD45-PerCP (2D1, BD Bioscience, 1:25), IgG-BV480 (goat polyclonal ...
• AP2A1 is upregulated upon replicative senescence of human fibroblasts to strengthen focal adhesions via integrin β1 translocation along stress fibers

  Pirawan Chantachotikul, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-paxillin (1:200, #610569, BD Biosciences), anti-integrin β1 (1:200 ...
• Deciphering Neuronal Deficit and Protein Profile Changes in Human Brain Organoids from Patients with Creatine Transporter Deficiency

  Léa Broca-Brisson, et al., bioRxiv - Neuroscience 2023

  Quote: ... pSer9-GSK3β 1:500 (BD Biosciences, 610201), SOX2 1:200 (Abcam ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-p120-catenin (1:400, BD Biosciences ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CD80 (APC, BD Biosciences, FUN-1), anti-CD86 (V450 ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... E-cadherin (612130; 1:150; BD Biosciences), and GFP (SC-8334;1:150 ...
• Phosphoprotein dynamics of interacting tumor and T cells by HySic

  Sofía Ibáñez-Molero, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD137-APC (1:100, BD Biosciences, 550890), CD69-PE (1:100 ...
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CD25 (BD, #741365, diluted 1:20), anti-CD279 (BD ...
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CD8 (BD, #563919, diluted 1:80), anti-CD69 (BD ...
• Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

  Irina Veith, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CD4 (BD, #566804, diluted 1:40), anti-CD8 (BD ...