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351 - 400 of 762 citations for Astrovirus Antigen Type 1 since 2019

• Abscission Checkpoint Bodies Reveal a New Facet of Abscission Checkpoint Control

  Lauren K. Williams, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 µM DYRK3 inhibitor (GSK 626616, Tocris, Minneapolis, MN), 1 µM CLK1 inhibitor (534350 ...
• Reversible silencing of endogenous receptors in intact brain tissue using two-photon pharmacology

  Silvia Pittolo, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... and 1 μM TTX (NaV channel blocker, Tocris 1069) to isolate Ca2+-events solely induced by mGlu5 activation (hereafter ...
• Cdk5 and GSK3β inhibit Fast Endophilin-Mediated Endocytosis

  Antonio P. A. Ferreira, et al., bioRxiv - Cell Biology 2020

  Quote: ... Torin 1 (called ‘mTORC1i’ in this study, Tocris 4247), VX-745 (called ‘p38i’ in this study ...
• Nanchangmycin regulates FYN, FAK and ERK to control the fibrotic activity of hepatic stellate cells

  Wenyang Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1-Naphthyl PP1 was purchased from Tocris (cat# 3063). Thapsigargin (Sigma-Aldrich ...
• Neural Mechanism of Hunger-gated Food-seeking and Evaluating

  Young Hee Lee, et al., bioRxiv - Neuroscience 2022

  Quote: ... clozapine-n-oxide (Tocris, CNO, 1 mg/kg, i.p.) or vehicle (saline ...
• Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor to promote neutrophilic inflammation

  Mieko Tokano, et al., bioRxiv - Immunology 2022

  Quote: ... a PKA inhibitor (0–1 μM) (H-89, Tocris) plus adenosine (100 μM) ...
• Morphological and biochemical repercussions of Toxoplasma gondii infection in a 3D human brain neurospheres model

  Paulo Emílio Corrêa Leite, et al., bioRxiv - Neuroscience 2020

  Quote: ... and dual SMAD inhibitors 1 μM of dorsomorphin (Tocris) and 10 μM of SB431542 (Stemgent) ...
• Transcriptomics reveals amygdala neuron regulation by fasting and ghrelin thereby promoting feeding

  Christian Peters, et al., bioRxiv - Neuroscience 2022

  Quote: ... The drugs used were ghrelin (1 μg, #1465, Tocris), JMV2959 (5 μg ...
• A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain

  Ebru Ercan-Herbst, et al., bioRxiv - Neuroscience 2019

  Quote: ... 10 μM SB431542 (Selleckchem) and 1 μM Dorsomorphin (Tocris) and changed for 11 more days on daily basis ...
• Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis

  Sai Zhang, et al., bioRxiv - Genomics 2020

  Quote: ... supplemented with SMAD inhibitors (DMH-1 2 μM Tocris, Cat. ...
• A new class of cell wall-recycling L,D-carboxypeptidase determines β-lactam susceptibility and morphogenesis in Acinetobacter baumannii

  Yunfei Dai, et al., bioRxiv - Microbiology 2021

  Quote: ... bacteria were pulsed with 1 mM HADA (Tocris Bioscience) for 15 minutes ...
• Calcium-independent astrocytic lipid release modulates neuronal excitability

  Fushun Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... N-(2,6-dimethylphenylcarbamoylmethyl) triethylammonium chloride (QX314, 1 mM, Tocris); 4-(4-,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl ...
• Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells

  Paul O’Callaghan, et al., bioRxiv - Cell Biology 2020

  Quote: ... was diluted to 1 mM and Cyclosporin A (Tocris) was diluted to 100 mM in DMSO and stored at −20°C ...
• Transcriptomics reveals amygdala neuron regulation by fasting and ghrelin thereby promoting feeding

  Christian Peters, et al., bioRxiv - Neuroscience 2022

  Quote: ... different amounts of ghrelin (1-10 μg, #1465, Tocris), ghrelin receptor antagonist JMV2959 (250 μg ...
• Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy

  Raphael S. Peres, et al., bioRxiv - Immunology 2022

  Quote: ... AP-1 inhibitor (AP-1i, SR11302, 10 uM, Tocris), STAT3 inhibitor (STAT3i ...
• PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size

  Tomoaki Sobajima, et al., bioRxiv - Cell Biology 2023

  Quote: ... along with 1-10 µM MPS1 inhibitor (TOCRIS, AZ3146) or DMSO (Merck ...
• The synapsin-dependent vesicle cluster is crucial for presynaptic plasticity at a glutamatergic synapse in male mice

  Felicitas Bruentgens, et al., bioRxiv - Neuroscience 2023

  Quote: ... we applied 1 µM DCG-IV (#0975, Tocris Bioscience) at the end of each experiment (Kamiya et al. ...
• AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML

  Ece Canan Sayitoglu, et al., bioRxiv - Immunology 2023

  Quote: ... LFA-1 inhibitors (BIRT377, BMS688571 and A286982 from Tocris Bioscience ...
• Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish

  Fusun Doldur-Balli, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and ZD7288 (Tocris, Cas Registry No. 133059-99-1) were tested in this study ...
• Reprogramming early cortical astroglia into neurons with hallmarks of fast-spiking parvalbumin-positive interneurons by phospho-site deficient Ascl1

  Nicolás Marichal, et al., bioRxiv - Neuroscience 2023

  Quote: ... tetrodotoxin (TTX, 1 µM, Tocris, Bio-Techne, Minneapolis, USA) to block Na channels or 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
• The Essential Role of Latrophilin-1 Adhesion GPCR Nanoclusters in Inhibitory Synapses

  Daniel Matúš, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 spermine and 10 QX-314 (Tocris Cat# 1014) (pH 7.3 ...
• Chemical screens in aging-relevant human motor neurons identify MAP4Ks as therapeutic targets for amyotrophic lateral sclerosis

  Meng-Lu Liu, et al., bioRxiv - Neuroscience 2023

  Quote: ... Kenpaullone (Ken) and A83-1 were obtained from Tocris. Forskolin (FSK) ...
• Leucine Rich Repeat Kinase 2 is not required for lysozyme expression in intestinal Paneth cells

  Anna Tasegian, et al., bioRxiv - Physiology 2024

  Quote: ... 1 μM Y-27632 dihydrochloride (ROCK inhibitor, Tocris, #1254) on a horizontal shaker for 30 minutes at 37ºC ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1 µM Prostaglandin E2 (2296; Tocris Bioscience, Bristol, UK), 1.25 mM N-Acetyl-L-cysteine (A8199 ...
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

  Or-Yam Revach, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 1 nM of FK866 NAMPT inhibitor (Tocris, 4808). S1 and S3 were banked using BAMBANKER freezing media (Bulldog Bio ...
• Lipotype acquisition during neural development in vivo is not recapitulated in stem cell-derived neurons

  Anusha B. Gopalan, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and 1% Pen/Strep) +2iLIF (10 ng/ml leukemia inhibitory factor + 3 μM CHIR99021 + 1 μM PD0325901 from Tocris, Cat. # 4423 and 4192, respectively). The cells were grown on 0.1% gelatin-coated dishes and usually seeded at a density of 0.5–1.5 × 104/cm2 ...
• Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis

  Andrew S. Riching, et al., bioRxiv - Cell Biology 2020

  Quote: ... or 0.5 μM or 1 μM GSK-J4 (Tocris 4594) were administered starting at 72 hours post-infection ...
• Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling

  Douglas G. Brownfield, et al., bioRxiv - Developmental Biology 2022

  Quote: ... the irreversible Fgfr2 inhibitor FIIN-1 (14.75 mg/kg, Tocris)71–73 or recombinant Fgfr2iiib-Fc (100µg/30g mouse ...
• Calcium-induced calcium release in noradrenergic neurons of the locus coeruleus

  Hiroyuki Kawano, et al., bioRxiv - Neuroscience 2019

  Quote: ... by adding 1 µM tetrodotoxin (Tocris Bioscience, Ellisville, MO, USA) and 10 µM LaCl3 to the external solutions ...
• SYNAPTIC RELEASE POTENTIATION AT AGING AUDITORY RIBBON SYNAPSES

  Thibault Peineau, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 1 µM of XE-991 (Tocris Bioscience; cat # 2000) to block SK channels and KCNQ4 channels ...
• Intronic enhancer region governs transcript-specific BDNF expression in neurons

  Jürgen Tuvikene, et al., bioRxiv - Neuroscience 2020

  Quote: ... cultured neurons were pre-treated with 1 μM tetrodotoxin (Tocris) until the end of the experiment to inhibit spontaneous neuronal activity ...
• Serotonin neurons modulate learning rate through uncertainty

  Cooper D. Grossman, et al., bioRxiv - Neuroscience 2020

  Quote: ... we injected either 3.0 mg kg−1 agonist 21 (Tocris) dissolved in 0.5% DMSO/saline or an equivalent volume of vehicle (0.5% DMSO/saline alone ...
• Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates

  Amanda H Klein, et al., bioRxiv - Neuroscience 2020

  Quote: ... followed by BAM8-22 (1 μg in saline, Tocris Biosciences). Each injection (volume 10 μl ...
• Wilms Tumorigenesis in Human Kidney Organoids

  Verena Waehle, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1% Penicillin-Streptomycin) supplemented with 8 µM CHIR99021 (Tocris #4423) and 5 ng/ml Noggin (Peprotech #120-10C ...
• Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice

  Suzanne Lam, et al., bioRxiv - Neuroscience 2022

  Quote: ... Slices were stained by MXO4 dye (Tocris #4920, 1/300) for 30 min at room temperature ...
• EMC10 reduction in human neurons and adult mouse brain rescues cellular and behavioral deficits linked to 22q11.2 deletion

  Pratibha Thakur, et al., bioRxiv - Neuroscience 2022

  Quote: ... PD0325901 (1 μM; catalog#4192, Tocris Bioscience, Bristol, United Kingdom), SU5402 (5 μM ...
• PKC regulates the production of fibroblast growth factor 23 (FGF23)

  Ludmilla Bär, Philipp Hase, Michael Föller, bioRxiv - Physiology 2019

  Quote: ... with or without 1 μM PKC inhibitors Calphostin C (Tocris), Gö6976 (Tocris) ...
• Tandem Requirement for Full Renal D₁R and D₅R Activity

  Selim Rozyyev, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Ouabain (50 μM, 1 hr, #1076, Tocris Bioscience, Bristol, UK), added to the basolateral area ...
• Neutrophil-derived extracellular vesicles: proinflammatory trails and anti-inflammatory microvesicles

  Young-Jin Youn, et al., bioRxiv - Immunology 2019

  Quote: ... Inhibitor of Rac-1 GTPase (NSC23766, 10 μM, Tocris bioscicence), inhibitor of actin polymerization (Cytochalasin D ...
• Single-cell RNA sequencing reveals a role for reactive oxygen species and peroxiredoxins in fatty-acid-induced rat ß-cell proliferation

  Alexis Vivoli, et al., bioRxiv - Cell Biology 2021

  Quote: ... 10058-F4/1-RH was from Tocris (Bristol, United Kingdom).
• ACSL3 is a novel GABARAPL2 interactor that links ufmylation and lipid droplet biogenesis

  Franziska Eck, Manuel Kaulich, Christian Behrends, bioRxiv - Cell Biology 2020

  Quote: ... Torin 1 (Tocris, 4247, 250 nM in DMSO, 2 hrs), Bortezomib (LC Labs B-1408 ...
• eIF4E3 Forms an Active eIF4F Complex during Stresses (eIF4F^S) Targeting mTOR and Re-Programs the Translatome

  B. Weiss, et al., bioRxiv - Molecular Biology 2021

  Quote: ... or for 1 hr with 50 μM Ly29004 (Tocris Biosciences) before collection ...
• The Aurora B gradient sustains kinetochore stability in anaphase

  Diana Papini, et al., bioRxiv - Cell Biology 2021

  Quote: ... cells were treated with 1 to 10 µM ZM447439 (Tocris) for 3 to 15 min ...
• Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs

  Tanja Fuchsberger, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 µM PKA inhibitor fragment (6-22) amide (Tocris Bioscience), 0.5 mM anisomycin (stock solution in EtOH ...
• Ketamine’s rapid antidepressant effects are mediated by Ca²⁺-permeable AMPA receptors in the hippocampus

  Anastasiya Zaytseva, et al., bioRxiv - Neuroscience 2023

  Quote: ... 20 μM 1-Naphthyl acetyl spermine trihydrochloride (NASPM, Tocris, 2766) was used to block CP-AMPARs in cultured hippocampal excitatory neurons ...
• Mu-opioid receptor-dependent changes in social reward across adolescence in mice

  Zofia Harda, et al., bioRxiv - Neuroscience 2023

  Quote: ... injection of cyprodime hydrochloride 1 hour before the posttest (TOCRIS, cat ...
• Selective inhibition of fibroblast-specific Domain Discoidin Receptor 1 (DDR1) reduces collagen deposition and modulates fibroblast-specific cytokine release within the breast microenvironment

  Daniel E.C. Fein, et al., bioRxiv - Cell Biology 2023

  Quote: ... Media without or without DDR1 inhibitor (DDR1-IN-1 [Tocris 5077] or 7rh [Tocris 5860] was added and gel contraction quantified at 8-16 hours ...
• Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation

  Soumitra Ghosh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... the AR degrading PROTAC ARCC4 (1 µM, Tocris, Cat# 7254), or ethanol ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... 0.2 or 1 mM HIF-1α inhibitor (5655, Tocris Bioscience), 6.5 μM Dimethyl Fumarate (DMF ...
• Integrin-based adhesions promote cell-cell junction remodelling and cytoskeletal rearrangements to drive embryonic wound healing

  Michelle Ly, et al., bioRxiv - Cell Biology 2023

  Quote: ... Embryos were injected with 1 mM RGDS peptide (Tocris Bioscience) in water ...