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1 - 50 of 216 citations for ACETOXY DECANOIC ACID since 2020

• Excitoprotective effects of conditional tau reduction in excitatory neurons and in adulthood

  Yuliya Voskobiynyk, et al., bioRxiv - Neuroscience 2024

  Quote: Kainic acid (Tocris) was dissolved in PBS at a concentration of 2 mg/ml with intensive sonication ...
• In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors

  Yu Zheng, et al., bioRxiv - Neuroscience 2024

  Quote: ... γ-aminobutyric acid (Tocris), glutamate (Sigma-Aldrich) ...
• Dopamine D1 receptor activation and cAMP/PKA signalling mediate Brd4 recruitment to chromatin to regulate gene expression in rat striatal neurons

  Jace Jones-Tabah, et al., bioRxiv - Neuroscience 2021

  Quote: ... quisqualic acid (QA – Tocris), and N-methyl-D-aspartic acid (NMDA ...
• Aminooxadiazolyl kainic acid reveals that kainic acid receptors contribute to astrocytoma glutamate signaling

  Mitra Sadat Tabatabaee, et al., bioRxiv - Neuroscience 2021

  Quote: ... kainic acid (Tocris 0222), Ph-KA (made in-house) ...
• Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex

  Stephen D. Glasgow, et al., bioRxiv - Neuroscience 2020

  Quote: ... flufenamic acid (4522, Tocris), nifedipine (1075 ...
• LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

  Riccardo Sirtori, et al., bioRxiv - Neuroscience 2024

  Quote: ... Valproic acid (0.5mM, Tocris) was added on day 13 ...
• MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription

  Jun Young Sonn, et al., bioRxiv - Molecular Biology 2024

  Quote: ... kainic acid (Tocris; 0222) was dissolved in 0.9% sodium chloride solution (Henry Schein ...
• Low-cost platform for multi-animal chronic local field potential video monitoring with graphical user interface (GUI) for seizure detection and behavioral scoring

  Gergely Tarcsay, et al., bioRxiv - Neuroscience 2022

  Quote: ... Kainic acid (KA) (Tocris, USA) was dissolved in saline to provide a solution with a concentration of 20 mM ...
• Low Molecular Weight Hyaluronan Inhibits Lung Epithelial Ion Channels by Activating the Calcium-Sensing Receptor

  Ahmed Lazrak, et al., bioRxiv - Physiology 2022

  Quote: ... Retinoic Acid (Tocris Bioscience, 069550); BSA (Gibco ...
• Higher synaptic threshold for NMDA spike generation in human neurons

  Guilherme Testa-Silva, et al., bioRxiv - Neuroscience 2021

  Quote: L-Glutamic acid (Tocris, UK) was dissolved in ACSF to a concentration of 200 mM and the pH adjusted to 7.4 with NaOH ...
• Sodium channel endocytosis drives axon initial segment plasticity

  Amélie Fréal, et al., bioRxiv - Neuroscience 2023

  Quote: ... Okadaic Acid (Tocris Bioscience, #1136), Tautomycetin (Tocris Bioscience ...
• Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

  Lucas Caldi Gomes, et al., bioRxiv - Neuroscience 2024

  Quote: ... L-glutamic acid (Tocris, UK) was dissolved in 50 mM NaOH ...
• Intermediate Gray Matter Interneurons in the Lumbar Spinal Cord Play a Critical and Necessary Role in Coordinated Locomotion

  Naëmi Kuehn, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1mM kainic acid (1mM; Tocris) injections ...
• Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo

  Shu Xie, et al., bioRxiv - Neuroscience 2024

  Quote: ... GABA (γ-aminobutyric acid; Tocris), DA (Sigma-Aldrich) ...
• Gz Enhanced Signal Transduction assaY (G_ZESTY) for GPCR deorphanization

  Luca Franchini, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... 1-oleoyl lysophosphatidic acid (Tocris), DAMGO (MedChemExpress) ...
• Spinal cerebrospinal fluid contacting neurons are a conserved sensory neuronal population along the mouse spinal cord

  Crozat Elysa, et al., bioRxiv - Neuroscience 2024

  Quote: ... γ-aminobutyric acid (GABA, Tocris Bioscience), glycine (Gly ...
• Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2

  Linda Pesonen, et al., bioRxiv - Cell Biology 2021

  Quote: ... gambogic acid (GB, 3590, Tocris Bioscience) or gambogenic acid (GBA ...
• Optical analysis of the action range of glutamate in the neuropil

  E.A. Matthews, et al., bioRxiv - Neuroscience 2021

  Quote: ... 70 nl kainic acid (20mM, Tocris) was injected above the left hippocampal CA1 region (−2AP −1.4ML −1.1DV ...
• Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

  Carlos A. Tristan, et al., bioRxiv - Bioengineering 2020

  Quote: ... and Ascorbic Acid (200 μM, Tocris) for 2 weeks ...
• Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

  Carlos A. Tristan, et al., bioRxiv - Bioengineering 2020

  Quote: ... and Ascorbic Acid (200 μM, Tocris) and maintained in suspension in ULA T-175 flasks ...
• Mechanisms Controlling Hemolymph Circulation Under Resting Conditions In The Chagas Disease Vector Rhodnius Prolixus (Stål)

  María José Villalobos Sambucaro, et al., bioRxiv - Physiology 2023

  Quote: ... N‘-tetra-acetic acid (Tocris Bioscience) -300 µM and 400 µM- ...
• Stem cells tightly regulate dead cell clearance to maintain tissue fitness

  Katherine S Stewart, et al., bioRxiv - Cell Biology 2023

  Quote: ... and arachidonic acid (all Tocris Bioscience) were each dissolved in 100% ethanol and stored like the retinoids ...
• Patho-transcriptomic analysis of invasive mucinous adenocarcinoma of the lung (IMA): comparison with lung adenocarcinoma with signet ring cell features (SRCC)

  William D. Stuart, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Mycophenolic acid/MPA (cat# 1505, Tocris) or Sorafenib (cat# 6814 ...
• KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons

  Irune Guerra San Juan, et al., bioRxiv - Neuroscience 2024

  Quote: ... retinoic Acid (RA, 1 µM, Tocris) and smoothened agonist (SAG ...
• Novel Mouse Model of Alternating Hemiplegia of Childhood Exhibits Prominent Motor and Seizure Phenotypes

  Nicole A. Hawkins, et al., bioRxiv - Neuroscience 2024

  Quote: Kainic acid (KA, Tocris, Bristol, UK) was administered intraperitoneally at 25 mg/kg to 16-22 mice per genotype which were then video recorded for 2 hours ...
• Recombinant B3 clade enterovirus D68 strains are efficiently rescued in 293T cells and infect human spinal cord organoids

  Jennifer E. Jones, et al., bioRxiv - Microbiology 2024

  Quote: ... and 100 nM retinoic acid (Tocris).
• Interictal spikes during spatial working memory carry helpful or distracting representations of space and have opposing impacts on performance

  Justin D. Yi, et al., bioRxiv - Neuroscience 2024

  Quote: Kainic Acid (Tocris Bioscience, ItemNo: 0222:) was prepared by combining 50mg of KA powder with a 40mM Sodium hydroxylate solution to get a stock solution of 40mM Kainate ...
• Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis

  Vukasin M. Jovanovic, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 200 µM ascorbic acid (4055, Tocris).
• Long-range GABAergic inhibition modulates spatiotemporal dynamics of the output neurons in the olfactory bulb

  Pablo S. Villar, Ruilong Hu, Ricardo C. Araneda, bioRxiv - Neuroscience 2020

  Quote: ... kynurenic acid sodium salt (Catalog #3694, Tocris).
• TASK-3 Two-Pore Potassium Channels drive neuronal excitability of the circadian clock and entrainment to challenging light environments

  Aiste Steponenaite, et al., bioRxiv - Neuroscience 2020

  Quote: L-Glutamic acid was purchased from Tocris Bioscience ...
• Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility

  Rafael T. Han, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Kainic acid (KA; Tocris, United Kingdom) were dissolved in normal saline and freshly prepared ...
• The hippocampus and dorso-lateral striatum link distinct types of memories through time and space, respectively

  Janina Ferbinteanu, bioRxiv - Neuroscience 2020

  Quote: ... or a solution of quinolinic acid (Tocris; 25mg/ml in phosphate buffer titrated with sodium hydroxide to pH 7.4 ...
• Cortical and raphe GABA_A, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine

  Thu Ha Pham, et al., bioRxiv - Neuroscience 2020

  Quote: ... dihyrokainic acid (DHK, Tocris Bioscience, Lille, France) was dissolved in the aCSF and perfused at 5 mM for 2.5 hours according to Gasull-Camos et al. ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... all trans retinoic acid (0.1 µM, Tocris), BDNF (20ng/ml ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... all trans retinoic acid (0.1 µM, Tocris), and ROCK inhibitor Y-27632 (10 µM ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... all trans retinoic acid (0.1 µM, Tocris), and ROCK inhibitor Y-27632 (10 µM ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... all trans retinoic acid (0.1 µM, Tocris), BDNF (20ng/ml ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... all-trans retinoic acid (0.1 µM, Tocris), LDN-193189 (100 nM ...
• A generic binding pocket for small molecule I_Ks activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

  Magnus Chan, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Mefenamic acid (Tocris Bioscience, Oakville, ON, Canada) was used to activate IKs at concentrations of 100 μM and 1 mM.
• Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

  Kizito-Tshitoko Tshilenge, et al., bioRxiv - Neuroscience 2022

  Quote: ... ascorbic acid (2 mM, Tocris Bioscience, 4055). Medium was passed through a 0.22-µm filter ...
• Structure-guided engineering of a fast genetically encoded sensor for real-time H₂O₂ monitoring

  Justin Daho Lee, et al., bioRxiv - Bioengineering 2024

  Quote: ... Stock solution of Cyclopiazonic Acid (Tocris, 1235) was prepared in 100% DMSO at 20mM ...
• Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS

  Laurène Adam, et al., bioRxiv - Biophysics 2023

  Quote: ... Kainic acid (KA) was obtained from Tocris Bioscience (Bristol ...
• Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

  Delfina Larrea, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 100 nM retinoic acid (RA) (Tocris 1254) and 500 nM Smoothened Agonist (SAG Stemcell Technologies 73414) ...
• Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis

  Célia Alecki, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and 0.5 mM valproic acid (Tocris, #2815)) on Matrigel-coated plates ...
• Interictal spikes during spatial working memory carry helpful or distracting representations of space and have opposing impacts on performance

  Justin D. Yi, et al., bioRxiv - Neuroscience 2024

  Quote: ... 70nL of 20mM Kainate Acid (Tocris Bioscience) or saline was injected unilaterally into cortex above right hippocampus (M/L =1.5mm ...
• Tuba1a is uniquely important for axon guidance through midline commissural structures

  Georgia Buscaglia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and 1mM kynurenic acid (Tocris Bioscience, Bristol, UK). Meninges were removed and cortices were dissected and cut into approximately 1mm pieces ...
• Synapse development is regulated by microglial THIK-1 K⁺ channels

  Pablo Izquierdo, et al., bioRxiv - Neuroscience 2021

  Quote: ... or kainic acid (Tocris, 1 μM; Tocris 0222) were bath-applied sequentially (ensuring that holding current returned to the original control level before subsequent drug application ...
• Synapse development is regulated by microglial THIK-1 K⁺ channels

  Pablo Izquierdo, et al., bioRxiv - Neuroscience 2021

  Quote: ... or kainic acid (Tocris, 1 μM; Tocris 0222) were bath-applied sequentially (ensuring that holding current returned to the original control level before subsequent drug application ...
• Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening

  Caroline E. Strong, et al., bioRxiv - Bioengineering 2022

  Quote: ... and 20 nM ascorbic acid (Tocris, cat# 4055). A stock solution consisting of all materials except cAMP and ascorbic acid was prepared in advance ...
• Reduced Hippocampal Inhibition and Enhanced Autism-Epilepsy Comorbidity in Mice Lacking Neuropilin 2

  Carol Eisenberg, et al., bioRxiv - Neuroscience 2021

  Quote: ... kynurenic acid (3 mM KyA, Tocris, Ellisville, MO) in the recording aCSF ...