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Citations for Tocris :
601 - 650 of 693 citations for 8 Fluoro quinazoline 2 4 diamine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Microbiology 2024Quote: To investigate the impact of gallein (3’,4’,5’,6’-Tetrahydroxyspiro[isobenzofuran-1(3H),9’- (9H)xanthen]-3-one) (Cat#3090, Tocris, Minneapolis, MN) and/or INH on Mtb growth ...
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bioRxiv - Neuroscience 2019Quote: ... (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3’,2’,1’-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester (K252a, 200 nM) (Tocris), 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one (DHF ...
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bioRxiv - Neuroscience 2021Quote: Bilateral mosaic tadpoles expressing GCaMP6s at stage 48 were immobilized in 2 mM pancuronium dibromide (Cedarlane/Tocris 0693) and embedded in 1% low melting point agarose in a petri dish filled with 0.1X MBSH ...
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bioRxiv - Neuroscience 2021Quote: ... Eye movements were prevented by injection of a-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Developmental Biology 2021Quote: ... paraxial mesoderm (1 day; 20 ng/ml FGF2, 3 µM CHIR99021, 2 µM SB505124 [cat. num. 3263; Tocris Bioscience ...
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bioRxiv - Neuroscience 2021Quote: ... Eye movements were prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Neuroscience 2021Quote: ... the group 2/3 mGluR agonist (DCG-IV) and MNI-glutamate for uncaging experiments were purchased from Tocris Bioscience ...
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bioRxiv - Neuroscience 2019Quote: ... Eye movements were prevented by injection of a-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye ...
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bioRxiv - Genomics 2019Quote: ... On D3 medium was changed to 1:1 mix of spent and fresh RPMI Minus supplemented with 7.5μM IWP-2 (Tocris). On D5 ...
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bioRxiv - Neuroscience 2020Quote: ... Eye movements were prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Neuroscience 2021Quote: ... the same routine was repeated in the presence of the glutamate transport blocker TFB-TBOA 2 μM (Tocris). For both traces the fluorescence change was calculated from the average of the baseline fluorescence intensities for each ROI as ΔF/F = (FSBFI - FSBFI(baseline)/FSBFI(baseline) ...
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bioRxiv - Biochemistry 2021Quote: ... cells were treated with either DMSO or 1 µM of LRRK2 kinase inhibitor (MLi-2, cat.no. 5756, TOCRIS) for 90 mins and then examined for localization ...
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bioRxiv - Cell Biology 2020Quote: ... the γ-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine1,1-dimethylethyl ester (DAPT) (Tocris) was added at a concentration of 5 μM ...
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bioRxiv - Genomics 2019Quote: ... 20ng/ml human LIF (all from WT-MRC Cambridge Stem Cell Institute) and 2 μM Gö6983 (PKCi; Tocris) on Matrigel–coated plates (Corning) ...
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bioRxiv - Neuroscience 2022Quote: Rats were bilaterally infused with either the selective α4β2 nicotinic antagonist DHβE (low dose: 15μg/.5μL/side, high dose 30μg/.5μL/side; Tocris Bioscience, Bristol, UK) the non-selective dopamine receptor antagonist Flupenthixol (15μg/.5μl/side ...
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bioRxiv - Biophysics 2022Quote: ... the 2-methylphenylureaphenylacetyl (MUPA) moiety with LDVPAAK peptide (MUPA-LDVPAAK; now commercially available, Tocris, 7020, supplementary Fig. 12) was custom synthesized by Bio-Synthesis and the amine group of its lysine side chain was reacted with the NHS group of sulfo-SMCC ...
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bioRxiv - Cell Biology 2022Quote: ... LPS was washed off and the macrophages were treated with 2 μM MK6-83 (cat no. 5547, Tocris), 20 μM MLSA-1 (cat ...
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bioRxiv - Genomics 2023Quote: ... and seeded at a seeding density of 10,000–25,000 cells/cm2 in mTeSR supplemented with 2 μM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Neuroscience 2023Quote: ... GRP was applied to the spinal cord to evoke Ca2+ oscillations and 2-APB (100 µM, Tocris 1224) 10 min later ...
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bioRxiv - Neuroscience 2023Quote: All recordings were done in ACSF-2 without or with 10 μM DQP 1105 (Tocris Bio-Techne, France), 10 μM DQP 1105 + 1μM Ro 25-6981 (Tocris Bio-Techne ...
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bioRxiv - Biophysics 2023Quote: ... whereas IS-2 sample was made up to 100 µM CTZ and 100 µM GYKI- 52466 (Tocris, 1454) prior to centrifugation (75,000 g ...
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bioRxiv - Neuroscience 2023Quote: ... Candidate ASM order information was as follows: 1-Ethyl-2-benzimidazolinone (Alternative name 1-EBIO, Tocris, CAS: 1041), AA43279 (Focus biomolecules ...
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bioRxiv - Neuroscience 2021Quote: ... and MNI-caged-L-glutamate ((S)-α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid) were purchased from Tocris (Bristol, UK). Rhod-2 tripotassium salt was purchased from AAT Bioquest (Sunnyvale ...
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bioRxiv - Neuroscience 2021Quote: ... d-2-Amino-5-phosphonovaleric acid (d-AP5, 50µM) and the sodium (Na+) channel blocker tetrodotoxin (TTX, 1 µM Tocris). Individual traces (5 sec duration ...
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bioRxiv - Neuroscience 2021Quote: ... and nor-Binaltorphimine dihydrochloride (norBNI, KOR antagonist, 10 mg/kg, i.p.) (CAS# 113158-34-2) were obtained from Tocris and dissolved in 0.9% sterile saline ...
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bioRxiv - Neuroscience 2019Quote: ... To prevent eye movement during recordings α-bungarotoxin (1 nl of 2 mg/ml; Tocris, Bristol, UK; Cat: 2133) was injected into the ocular muscles behind the eye.
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bioRxiv - Neuroscience 2019Quote: ... To block NMDA receptors we used D- (-)-2-Amino-5-phosphonopentanoic acid (D-AP5, Tocris, 10 μM final concentration). To block glycinergic inhibition ...
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bioRxiv - Biochemistry 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy] butanoic acid (DCPIB) was purchased from Tocris Bioscience and reconstituted to 50 mM in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... 20 μM 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 20 μM D-(-)-2-amino-5-phosphopentanoic acid (D-AP5) (Tocris Bioscience) to block glycine- ...
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bioRxiv - Neuroscience 2020Quote: ... CGP 55845 ((2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl) phosphinic acid hydrochloride) and GRK2i were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Cell Biology 2022Quote: To observe chromosome alignment in fixed-cell experiments – with the advantage of taking high resolution images and easily selecting many cells for further analysis - cells were released from thymidine block for 7 hours before being treated for 2 hours with RO-3306 (10μM, Tocris) – to synchronise cells at the G2/M boundary - or with a 3-hour treatment with STLC (10μM ...
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bioRxiv - Biophysics 2022Quote: ... 100 μM 2-APB blocking stretch-activated inositol triphosphate receptors (InsP3Rs) on the ER/nuclear membranes (Tocris Bioscience #1224), 100 μM CK-666 (Tocris Bioscience #3950 ...
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bioRxiv - Neuroscience 2019Quote: ... in the presence of the mGluR5 antagonist 2-methyl-6 (phenylethynyl)-pyridine (MPEP, 25 μM; Tocris Bioscience, Bristol, UK). Inhibitors were applied concomitantly from 30 min before to 30 min after DHPG/MPEP treatment ...
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bioRxiv - Neuroscience 2020Quote: ... were performed on mice with no knee injections 20 min before and after C21 (2 mg/kg diluted in sterile saline from a stock of 100 mM in ethanol, i.p., Tocris) injection.
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bioRxiv - Neuroscience 2021Quote: ... The mGluR5 specific negative allosteric modulator MPEP hydrochloride (2-Methyl-6-(phenylethynyl)pyridine hydrochloride) was purchased from Tocris (1212) and administered to brain slices at 30 μM by bath perfusion ...
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bioRxiv - Neuroscience 2021Quote: ... 4-(4-,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl) benzeneacetamide (GW627368X 3 µM, Tocris); 6-Isopropoxy-9-xanthone-2-carboxylic acid (AH6809 ...
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bioRxiv - Cell Biology 2021Quote: ... AKT (20 μM MK2206, Cayman Biochemicals #1032350-13-2) and myosin ATPase activity inhibitor (5 μM Blebbistatin, Tocris #1852).
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bioRxiv - Immunology 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid (DCPIB, 1540) was from Tocris. NS3728 and NBC19 were made at the University of Manchester.
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bioRxiv - Neuroscience 2023Quote: Pharmacological inhibition of AQP4 was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience, UK). Unless otherwise stated ...
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bioRxiv - Cell Biology 2023Quote: ... 3- (4,5-dimmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays were used to estimate cell number following the manufacturer’s description (Tocris, # 5224), and absorbance was measured at 550 nm in an EnsightTM 96-well plate reader (Perkin Elmer).
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Self-organised pattern formation in the developing neural tube by a temporal relay of BMP signallingbioRxiv - Developmental Biology 2023Quote: ... cells were dissociated from the 100 mm dishes and 2.8-3M cells per well were seeded on the prepared 2-well dishes in N2B27 medium with 10ng/ml bFGF + 10µM Y-27632 ROCK inhibitor (Tocris) media for 3h ...
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bioRxiv - Neuroscience 2021Quote: ... Four of the rats were also infused with 2 μL of either physiological saline or 5 μg/μL yohimbine (Tocris) with a flow rate of 0.5 μL/min as previously reported (Caetano et al. ...
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bioRxiv - Cell Biology 2019Quote: Human PSC were grown for 5 days in E8 media(Chen et al., 2011) without FGF-2 and TGF-b but supplemented with 10μM CHIR99021 (Tocris, 4423). Loss of pluripotency was confirmed by RT-qPCR panel of self-renewal ...
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bioRxiv - Genomics 2020Quote: ... The involvement of the TLR1/2 in signal transduction was tested using CU-CPT22 at 10 µM (Tocris Bioscience, UK). The used concentrations of inhibitors were selected based on recommendations provided by the manufacturers ...
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bioRxiv - Neuroscience 2020Quote: ... and the Mai Tai eHP was tuned to 725nm for photoactivation of recirculated caged MNI-L-glutamate (2 mM, Tocris)57,58 ...
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bioRxiv - Neuroscience 2020Quote: ... or by either bath application or using a custom-made perfusion system (for imaging cells on 12-mm coverslips): 2-AG (Tocris), AEA (Cayman) ...
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bioRxiv - Neuroscience 2020Quote: ... QX-314 (Cat No. 1014); and D-2-amino-5-phosphonovalerate (D-AP5; Cat No. 0106) were purchased from Tocris.
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bioRxiv - Neuroscience 2021Quote: Potassium currents were isolated pharmacologically during whole-cell voltage-clamp recordings by blocking fast sodium and calcium channels as well as ionotropic receptors for GABA and glutamate (2 µM tetrodotoxin (TTX, Tocris), 300 µM NiCl2 ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down ScalingbioRxiv - Neuroscience 2021Quote: ... 6 hrs (Figure 6 – figure supplement 2) or 24 hrs after transfection (the remaining experiments) neurons were treated with tetrodotoxin (TTX, 5 µM, Tocris) for ∼16 hours ...