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201 - 250 of 846 citations for 7 Octen 1 ol since 2019

• PTEN is required for human Treg suppression of costimulation

  Avery J. Lam, et al., bioRxiv - Immunology 2022

  Quote: ... PGE2 (1 μg/ml; Tocris) (all last 2 days) ...
• Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3

  Nienke Willemsen, et al., bioRxiv - Pathology 2022

  Quote: ... or 1 μM CL316,143 (Tocris) for 16 h ...
• IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

  Caterina Prelli Bozzo, et al., bioRxiv - Microbiology 2020

  Quote: ... Dorsomorphin 1 µM (Tocris, 3093), CHIR 99021 3 µM (Stemcell Technologies ...
• Modular Derivation and Unbiased Single-cell Analysis of Regional Human Hindbrain And Spinal Neurons Enables Discovery of Nuanced Transcriptomic Patterns along Developmental Axes

  Nisha R. Iyer, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 1 μM dorsomorphin (Tocris) to stimulate caudal NMP development ...
• LOCAL REGULATION AND FUNCTION OF IMPORTIN-β1 IN HIPPOCAMPAL NEURONS DURING TRANSCRIPTION-DEPENDENT PLASTICITY

  Yan Jun Lee, et al., bioRxiv - Neuroscience 2020

  Quote: ... Tetrodotoxin (TTX, 1 μM; Tocris), 4-Aminopyridine (4AP ...
• Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression

  Tyler J. Alban, et al., bioRxiv - Immunology 2019

  Quote: ... ISO-1 (Tocris Catalog # 4288)43 ...
• Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid-beta degrading enzyme in brain

  Per Nilsson, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 μM TT232 (Tocris, #4639), 10 nM Octreotide (Sigma ...
• Cellular Mechanisms Underlying Central Sensitization in a Mouse Model of Chronic Muscle Pain

  Yu-Ling Lin, et al., bioRxiv - Neuroscience 2022

  Quote: ... CGP-55845 (1 µM, Tocris), kynurenic acid (2 mM ...
• Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs

  Tanja Fuchsberger, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 mM MK801 (Tocris Bioscience).
• Retinoic acid accelerates the specification of enteric neural progenitors from in vitro-derived neural crest

  Thomas J.R Frith, et al., bioRxiv - Developmental Biology 2019

  Quote: ... 2μM SB431542 (Tocris 1614/1), 1μM DMH-1 (Tocris 4126/10) ...
• RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling

  Patricia M. Garay, et al., bioRxiv - Neuroscience 2019

  Quote: ... TTX (Tocris, 1069, 1 μM), or vehicle (sterile water) ...
• Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

  Rajendra Karki, et al., bioRxiv - Immunology 2020

  Quote: ... SIN-1 chloride (TOCRIS, 0750) at the indicated concentrations was used as the NO donor.
• Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells

  Muyesier Maimaitili, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 µM DAPT (Tocris Bioscience), GDNF (10 ng/ml) ...
• Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons

  ChangHui Pak, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 1 mM PD0325901 (Tocris)) ...
• Macrophage migration inhibitory factor is a valid drug target at the intersection of herpes simplex virus 1 replication and Alzheimer’s disease-relevant cellular pathology

  Andreas Müller-Schiffmann, et al., bioRxiv - Microbiology 2021

  Quote: ... and 1 µM dorsomorphin (Tocris)) ...
• Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR

  Gemma Danks, et al., bioRxiv - Genomics 2019

  Quote: ... Torin 1 from Tocris (#4247); protease inhibitor cocktail from Sigma-Aldrich (P2714-1BTL) ...
• Topoisomerase 2β-dependent nuclear DNA damage shapes extracellular growth factor responses through AKT phosphorylation dynamics to control virus latency

  Hui-Lan Hu, et al., bioRxiv - Molecular Biology 2019

  Quote: ... NU7441 (1 μM, 20hrs, TOCRIS), Mirin (100 μM ...
• Differential stimulation of pluripotent stem cell-derived human microglia leads to exosomal proteomic changes affecting neurons

  Anna Mallach, et al., bioRxiv - Neuroscience 2021

  Quote: ... and 1 µM dorsomorphin (Tocris). N2B27 medium was composed of 1:1 DMEM-F12 and Neurobasal medium ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... Torin 1 was from (Tocris-Biotechne ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and A8301 (1 μM; Tocris) for an additional 2 days ...
• Control of neurogenic competence in mammalian hypothalamic tanycytes

  Sooyeon Yoo, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 mg Cyclopamine (TOCRIS, #1623) powder was dissolved into 1 ml 2-hydroxylpropyl-beta-cyclodextrin (Sigma #C0926 ...
• Neuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription

  Wendy A. Herbst, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 μM tetrodotoxin (TTX, Tocris) was applied to the neurons for 1 hr ...
• Cryopreservation of midbrain dopaminergic neural cells differentiated from human embryonic stem cells

  Nicola J. Drummond, et al., bioRxiv - Cell Biology 2020

  Quote: ... and DAPT (1 μM, Tocris). From day 18 onwards medium was changed every 2-3 days.
• High-Throughput Human Primary Cell-Based Airway Model for Evaluating Influenza, Coronavirus, or other Respiratory Viruses in vitro

  A.L. Gard, et al., bioRxiv - Microbiology 2020

  Quote: ... 0.2 μM DMH-1 (Tocris), 0.5 μM CHIR99021 (Tocris ...
• Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration

  Jinwook Choi, et al., bioRxiv - Cell Biology 2021

  Quote: ... A83-01 (1 µM, Tocris), SB202190 (1 µM ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... IPA-3 (1 μM; Tocris), BDP-9066 (1 μM ...
• Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis

  Taisei Wakigawa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... BAI1 (Tocris, 2160, 1 μM), BTSA1 (Selleckchem ...
• Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

  Minee L. Choi, et al., bioRxiv - Neuroscience 2022

  Quote: ... and Dorsomorphin (1 µM, Tocris), dual SMAD inhibitors were treated in N2B27 medium (DMEM:F12 ...
• Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission

  Abhi Aggarwal, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 mM (S)-MCPG (Tocris)) ...
• SCN1A-deficient hiPSC-derived excitatory neuronal networks display mutation-specific phenotypes

  Eline J.H. van Hugte, et al., bioRxiv - Neuroscience 2023

  Quote: ... TTX (1 μM, Tocris, #1069) was used as a negative control ...
• A human primary airway microphysiological system infected with SARS-CoV-2 distinguishes the treatment efficacy between nirmatrelvir and repurposed compounds fluvoxamine and amodiaquine

  Landys Lopez Quezada, et al., bioRxiv - Bioengineering 2023

  Quote: ... 0.2 μM DMH-1 (Tocris), 0.5 μM CHIR99021 (Tocris ...
• Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release

  Xuehan Zhou, et al., bioRxiv - Neuroscience 2023

  Quote: ... Orphanin FQ (1-11) (Tocris); Leu-Enkephalin (Cayman) ...
• DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

  Seungsoo Kim, et al., bioRxiv - Genomics 2023

  Quote: dTAGV-1 (Tocris, 6914/5) was dissolved in DMSO at 5 mM and then diluted to 250 uM in 60% DMSO/40% water (v/v ...
• Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

  Yevgeniy V. Serebrenik, et al., bioRxiv - Cell Biology 2023

  Quote: dTAGV-1 (Tocris Bioscience, 6914) was used to degrade FKBPF36V-tagged proteins at the indicated concentrations and timescales (typically ∼24 hours).
• NMDA receptor misalignment in iPSC-derived neurons from a multi-generational family with inherited Creutzfeldt-Jakob disease

  Nhat T.T. Le, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 μM Dorsomorphin (Tocris). After forming a dense neuro-epithelial sheet ...
• Isogenic hiPSC models of Turner syndrome reveal shared roles of inactive X and Y in the human cranial neural crest network

  Darcy T. Ahern, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 μM DMH1 (Tocris Bioscience), 20 ng/mL BMP4 (Peprotech) ...
• Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

  Laura von Schledorn, et al., bioRxiv - Bioengineering 2023

  Quote: ... 1 μM A83-01 (Tocris), 0.2 μM DMH-1 (Tocris ...
• Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

  Laura von Schledorn, et al., bioRxiv - Bioengineering 2023

  Quote: ... 0.2 μM DMH-1 (Tocris) and 5 μM Y-27632 [41] ...
• Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

  Allen L. Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... and XAV939 (1 μM, Tocris) for 10 days of differentiation ...
• Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

  Benjamin L.L. Clayton, et al., bioRxiv - Neuroscience 2023

  Quote: ... XAV939 (1 μM; Tocris, 3748). Neural induction media consisted of 1:1 DMEM/F12 (ThermoFisher ...
• AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula

  S.C. Simmons, et al., bioRxiv - Neuroscience 2023

  Quote: ... strychnine (1 μM Tocris-2785) and tetrodotoxin (TTX ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 μM A83-01 (Tocris) and 1 μM DMH-1 (Tocris ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 μM A83-01 (Tocris), 1 μM DMH-1 (Tocris ...
• Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naïve PSCs

  Bernardo Oldak, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 µM LPA (Tocris, 3854), LIF 10ng/ml and 10 µM ROCKi Y2763 ...
• NOTCH3 signalling controls human trophoblast stem cell expansion and differentiation

  Bianca Dietrich, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 µM A83-01 (Tocris), 50 ng/ml recombinant human epidermal growth factor (rhEGF ...
• Heterogeneous subpopulations of GABAAR-responding neurons coexist in physiological and pathological mature neuronal networks at increasing scales of complexity

  I. Colombi, et al., bioRxiv - Neuroscience 2023

  Quote: ... or diazepam (1 μM; Tocris) were added by directly pipetting in the medium ...
• Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation

  Mirjam C van der Net, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 5 μM Yoda 1 (Tocris), 10 μM Y27632 (Gentaur) ...
• miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity

  Theresa M. Welle, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1 µM trichostatin A (Tocris) was added to cell media 16 h prior to iLTP induction ...
• Human pluripotent stem cell-derived respiratory airway progenitors generate alveolar epithelial cells and recapitulate features of idiopathic pulmonary fibrosis

  Mikael G. Pezet, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 1 μM IWP2 (Tocris)) for another 24 hours ...
• Reversible assembly and disassembly of V-ATPase during the lysosome regeneration cycle

  Ioana Sava, et al., bioRxiv - Cell Biology 2023

  Quote: ... Torin 1 was from Tocris Bioscience (Bristol ...