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Citations for Tocris :
451 - 500 of 554 citations for 7 Bromo 1H indazole 3 carboxylic acid since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2021Quote: ... our early pilot experiments assessed the impact of varying doses of Kainic Acid Monohydrate (KA, 0222, Tocris, Minneapolis, MN) on outcomes ...
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bioRxiv - Biochemistry 2021Quote: ... were recorded at 32°C in an interface-type chamber (perfusion rate 4.5 mL per minute) and elicited by applying kainic acid (100 nmol L-1, Tocris). The oscillations were stabilized for 20 min before any recordings ...
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bioRxiv - Biochemistry 2021Quote: Guanine unfolding experiments were performed by fluorescent dye assay using bis-ANS (4,4’-dianilino-1,1’-binaphthyl-5,5’-disulfonic acid, Tocris, Bristol, UK) as described previously(21 ...
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bioRxiv - Cancer Biology 2021Quote: ... the positive control consisted of a treatment with 1 μM 3-AP (#2251; Tocris) for 72 h.
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bioRxiv - Molecular Biology 2020Quote: Wild type zebrafish were exposed to 3 μM JWH-018 (Tocris, Cat. No. 1342), from 24 hours to six days post fertilization (dpf) ...
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bioRxiv - Developmental Biology 2023Quote: ... but on day 3 medium was changed for LY (1 µM LPA (Tocris, 3854) and 10 µM ROCKi Y27632 ...
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bioRxiv - Cell Biology 2023Quote: ... For the next 3 days CDBM with 0,6U/ml heparin and 3mM IWP2 (Tocris) was refreshed daily ...
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bioRxiv - Neuroscience 2023Quote: ... mice were intraperitoneally injected with either 3 mg per kg of scopolamine hydrobromide (Tocris) dissolved in saline or vehicle (saline) ...
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bioRxiv - Neuroscience 2021Quote: ... Glutamatergic neurons were identified by their characteristic EPSC time course and by sensitivity of EPSC to application of glutamate receptor antagonist kynurenic acid (Tocris). Synaptic currents were acquired at 10 kHz using pClamp 10.2 software (Molecular Devices ...
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bioRxiv - Neuroscience 2021Quote: ... and GluN2BGC−/− mice (P40 – P60) were stereotactically injected with 50 nl of 20 mM solution of kainic acid (Tocris / Biotechne) in 0.9 % NaCl to the left CA1 area of the dorsal hippocampus (AP −1.8 mm ...
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bioRxiv - Genomics 2021Quote: ... neurons were made quiescent for 2 hours with 100 μM D-2- amino-5-phosphonopentanoic acid (D-AP5; Tocris #0106) and 1 μM tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...
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bioRxiv - Neuroscience 2022Quote: Astrocytes grown in 6-well plates were refreshed with glial maintenance media or glial maintenance media supplemented with 100 μM L-Glutamic Acid (Tocris) for 3 h ...
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bioRxiv - Cell Biology 2023Quote: ... (Optopharma Ltd.) and 20 nM for 1-Oleoyl lysophosphatidic acid sodium salt (LPA) (5 mM stock dissolved in water) (Tocris). As controls ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141], 2.5 µM DAPT [Tocris, 2634] ...
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bioRxiv - Neuroscience 2021Quote: ... NMDA receptor (R) dependency was tested by application of an NMDAR antagonist (APV 50 µM, DL-2-Amino-5-phosphonopentanoic acid, Tocris, Germany) in the bath solution ...
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bioRxiv - Cell Biology 2021Quote: ... B/D medium was supplemented during submerged culture with 1 nM EC23 (light-stable retinoic acid receptor agonist; Tocris, Abingdon, UK). After confluence was reached ...
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Neuroscience 2023Quote: ... The following compounds were added to raCSF as indicated in the Results section: D-(-)-2-Amino-5-phosphonopentanoic acid (D-APV, 100 μM dissolved in H2O; Tocris Bioscience), (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine maleate (MK-801 ...
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bioRxiv - Neuroscience 2022Quote: ... was inserted into the guide cannula and a Hamilton Syringe was used to administrate 1 μL of 2 mM pyridoxalphosphate-6-azophenyl-2’,4’-disulfonic acid (PPADS, Tocris, 0625), 1.5 μg/μL S961 (Phoenix Pharmaceuticals ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141] ...
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bioRxiv - Neuroscience 2023Quote: ... Mice were injected intraperitoneally (i.p.) with 5.0mg/kg synthetic kainic acid (KA) dissolved in 0.9% saline (#7065, Tocris Bioscience, Bristol, United Kingdom). At twenty-minute intervals ...
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bioRxiv - Neuroscience 2021Quote: Varenicline or 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h] [3]benzazepine tartrate (Tocris, UK) was dissolved in sterile 0.9% physiological saline for a final dose of 1 mg/kg free base ...
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bioRxiv - Neuroscience 2020Quote: ... medium was exchanged every 3-4 days with RGC induction media containing: DAPT (3uM, Tocris), 10μM Rock inhibitor (Y27632) ...
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bioRxiv - Neuroscience 2021Quote: ... some slices were incubated at 37°C with 3 µM puromycin (Tocris #40-895-0) at 65-75 minutes post-slicing ...
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bioRxiv - Neuroscience 2022Quote: ... with the addition of either 3 μM or 10 mM GABA (Tocris; Cat. No. 0344). Sylgard 184 (Dow Corning ...
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bioRxiv - Neuroscience 2021Quote: AM251 pharmacology: in experiments using the CB1 antagonist AM251 (3 µM) (Tocris and AdooQ biosciences), the drug (diluted in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... with either 3 mg/kg clozapine N-oxide (CNO; Tocris, Catalog: 4936, Lot: 13D/233085) in 0.5% DMSO and saline ...
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bioRxiv - Neuroscience 2022Quote: ... mEPSCs were recorded in the presence of 3 μM AMPA receptor antagonist NBQX (Tocris Bioscience) in standard external solution.
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bioRxiv - Cell Biology 2023Quote: ... the CDBM medium was supplemented with 0.6 U/ml heparin and 3 mM IWP2 (Tocris) for another 3-day incubation with medium refreshed daily ...
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bioRxiv - Cancer Biology 2023Quote: ... N-(1,3,4-thiadiazol-2-yl) pyridine-3-carboxamide dihydrochloride (TGN-020, Tocris Cat No 5425) was used in vitro at 10-100 μM ...
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bioRxiv - Developmental Biology 2023Quote: ... N6,2’-O-Dibutyryladenosine 3’,5’-cyclic monophosphate sodium salt (DB-cAMP, TOCRIS Cat. No.: 1141), 8-(4-Chlorophenylthio)-N6-phenyladenosine-3’,5’-cyclic monophosphate sodium salt (8C6P-cAMP ...
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bioRxiv - Neuroscience 2021Quote: ... The bath solution usually contained 6,7-dinitroquinoxaline-2,3-dione (DNQX, 10 µM) and D- aminophosphonovaleric acid (D-APV, 50 µM) to block ionotropic glutamate receptors (Tocris, Abingdon, United Kingdom). Patch electrodes had resistances of 4-6 MΩ when filled with KMeSO4- or CMeSO4-based internal solution (same as used in vivo) ...
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bioRxiv - Neuroscience 2020Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) to block glutamatergic signaling (both from Tocris, Bristol, UK). Experiments involving tetrodotoxin (TTX ...
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bioRxiv - Immunology 2020Quote: ... These cells were then directed to become proepicardial cells by the addition of retinoic acid and WNT CHIR 99021 followed by TGFβ inhibition (SB431542, Tocris Bioscience 1614). Finally ...
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bioRxiv - Neuroscience 2023Quote: ... and cells were centrifuged at 200 rcf for 5 min and resuspended in N2B27 with the same supplements as on day 0 except for the removal of Y27632 and addition of all-trans retinoic acid (100 nM; Tocris, 0695/50) and SAG (500 nM ...
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bioRxiv - Developmental Biology 2021Quote: ... From passage 3 cells were grown NMP differentiation medium supplemented with 5 μM Y-27632 (Tocris). Human iPSCs were found to detach more readily than hESCs ...
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bioRxiv - Developmental Biology 2020Quote: ... short-term serum-free culture was carried out in N2B27 supplemented with 3 μM CHIR99201 (Tocris), 1 μg/ml of Heparin (Sigma ...
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bioRxiv - Developmental Biology 2020Quote: ... mTeSR Plus was replaced with the N2B27 basal medium supplemented with 3 μM CHIR99021 (Tocris Bioscience) and 40 ng/ml basic fibroblast growth factor bFGF/FGF2 (R&D Systems) ...
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bioRxiv - Neuroscience 2020Quote: ... each disk with neurons was transferred into the physiological saline solution containing NBQX (3 μM, Tocris) and bicuculine (30 μM ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Bioengineering 2021Quote: ... Plates were centrifuged at 100xg for 3 minutes in E8 medium containing 10 μM Y27632 (Tocris). The following day ...
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bioRxiv - Neuroscience 2023Quote: ... KA (3 mg/mL) was prepared on the day of experimentation by dissolving KA (Tocris, 0222) in a 0.9% bacteriostatic saline solution ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Neuroscience 2023Quote: The neural activity was reversibly suppressed using the GABA-A agonist 4,5,6,7-tetrahydro isoxazole [5,4-c]-pyridine-3-ol (THIP hydrochloride; Tocris). The THIP was dissolved in phosphate-buffered saline (PBS) ...
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bioRxiv - Neuroscience 2021Quote: ... free microdialysis probes (n=3) were inserted into a solution of 100nM adenosine (Tocris Biosciences, Bristol, U.K.) in Ringer’s Solution ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...