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Citations for Tocris :
451 - 496 of 496 citations for 7 1H Pteridinone 4 amino 6 methyl 9CI since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2020Quote: Recordings were performed in the presence of 1 µm TTX and 1 mM 4-AP (Tocris).
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bioRxiv - Neuroscience 2021Quote: ... recordings were performed in the presence of 1 µm TTX and 1 mM 4-AP (Tocris) to reveal pure monosynaptic inputs ...
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bioRxiv - Neuroscience 2024Quote: ... 4-(2-Butyl-6,7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB; Tocris), superoxide dismutase (SOD ...
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bioRxiv - Neuroscience 2024Quote: ... The following competitive antagonists were employed for microscopical experiments: trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline (L-689-560; Tocris); 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone (L-701-324 ...
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bioRxiv - Neuroscience 2024Quote: ... recordings were performed in the presence of 1 µM TTX and 1 mM 4-AP (Tocris). Data analysis was performed using MATLAB and Prism 8 (Graphpad) ...
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bioRxiv - Neuroscience 2024Quote: ... a non-selective opioid antagonist (0.5 mg/24 hours over 4 weeks, Tocris, Cat# 0599/100) or vehicle solution via an ALZET mini osmotic pump (Model 1004 ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...
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bioRxiv - Developmental Biology 2021Quote: ... early somite (1 day; 2 µM SB505124, 4 µM dorsomorphin, 500 nM PD173074 [cat. num. 3044; Tocris Bioscience ...
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Prelimbic proBDNF facilitates memory destabilization by regulation of neuronal function in juvenilesbioRxiv - Neuroscience 2022Quote: ... 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP; 32 ng/μL; Cat#01773, Tocris Bioscience), NVP-AAM077 (0.8 ng/μL ...
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Serotonin, Etonogestrel and breathing activity in murine Congenital Central Hypoventilation SyndromebioRxiv - Physiology 2022Quote: ... LP44 (4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide hydrochloride) was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Animal Behavior and Cognition 2022Quote: ... Either α-cyano-4-hydroxycinnamate (CHC, daily i.p. injection of 15 mg/kg, Tocris Bioscience, Bristol, UK) plus metformin (Met ...
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bioRxiv - Physiology 2023Quote: ... Reagents added to cell culture media are as follows: 250 μM 4-octyl itaconate (Tocris Bioscience, 6662), 4μM Etomoxir (Sigma ...
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bioRxiv - Neuroscience 2021Quote: ... Amyloid plaques were stained by the β-sheet dye Methoxy-X04 (4 μg/ml in 50% ethanol, Tocris) for 30 min at RT and contrasting in 50% ethanol ...
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bioRxiv - Neuroscience 2019Quote: ... The drugs used in this study are as follows: (±)-Bay K 8644 (catalog # 1544, Batch No. 4; Tocris), Nefiracetam (catalog # 2851 ...
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bioRxiv - Physiology 2022Quote: ... BPTU (1-(2-(2-(tert-butyl)phenoxy)pyridin-3-yl)-3-(4-(trifluoromethoxy) phenyl) urea was from Tocris Bioscience.
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bioRxiv - Molecular Biology 2022Quote: Parental A549 cells were fixed with 4% paraformaldehyde following 3-hour treatment with poly I:C (2.0 μg/mL, Tocris), LPS (1.0 μg/mL ...
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bioRxiv - Physiology 2023Quote: ... The dorsal muscle and skin were sutured with 4-0 sutures followed by injections of yohimbine (1.2 mg/kg, s.c.; Tocris), lactated Ringer’s solution (5 mL ...
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bioRxiv - Cell Biology 2020Quote: ... Cyclopiazonic-acid (CPA) and 2’(3’)-O-(4-Benzoylbenzoyl)adenosine-5’-triphosphate (BzATP) triethylammonium salt was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2019Quote: ... a final group of animals (n=4) received a DBB infusion of K-234 (1 nmol/0.5 µl/per side; Tocris Bioscience ...
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bioRxiv - Neuroscience 2019Quote: ... and substracted from background noise by detecting events in the last 4 seconds of 5 EPSCs at 0.2 Hz in 3 mM NBQX (Tocris) in extracellular solution.
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bioRxiv - Developmental Biology 2022Quote: ... zebrafish embryos were dechorionated with 1mg/ml pronase at 9 hpf and washed thoroughly with fresh Danieau’s buffer before being treated with 10μM (Z)-4-hydroxytamoxifen (#3412, Tocris, UK) for 2h at 28°C in the dark ...
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bioRxiv - Neuroscience 2020Quote: ... all electrophysiological recordings were performed in the presence of picrotoxin (100μM) and 3-((R)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP; 10μM; Tocris Bioscience), and a cut was made between CA3 and CA1 regions to prevent the propagation of epileptiform activity ...
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bioRxiv - Bioengineering 2021Quote: ... supplemented with FGF-2 (20 ng ml−1), Activin-A (50 ng ml−1), BMP-4 (10 ng ml−1, R&D) and LY294002 (10 mM Tocris). Media was changed again after 42 hours to CDM-BSA supplemented with FGF-2 (8 ng ml−1) ...
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bioRxiv - Neuroscience 2021Quote: ... mEPSCs were recorded in aCSF supplemented with 10 μM N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-2-naphthalen-1-ylacetamide trihydrochloride (NASPM, Tocris) to selectively block CP-AMPARs ...
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bioRxiv - Neuroscience 2020Quote: ... 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Neuroscience 2020Quote: ... The GAT1 blocker NO-711 [(1,2,5,6-tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride] and GAT3 blocker SNAP-5114 [1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid] were purchased from Tocris Bioscience (Minneapolis ...
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bioRxiv - Cell Biology 2021Quote: ... flow cytometer, and the fractions of stained cells were quantified using FloJo 10.6, with Staurosporine (4 h, 5 μM) (Tocris, 1285) used as a positive control for cell death and to help establish gating of the sorted cells.
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bioRxiv - Neuroscience 2019Quote: ... (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80) (20mg/kg; Tocris) dissolved in 1mM HCl in saline.
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bioRxiv - Developmental Biology 2021Quote: ... Neural progenitors were briefly washed (with DMEM/F12) and were then treated with CDM2 basal media supplemented with CHIR99021 (4 μM; Tocris), SB-505124 (2 μM ...
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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bioRxiv - Neuroscience 2022Quote: ... 12-well plates at 3-4 × 105 cells/well in mTeSR1 with 10 µM rho-kinase inhibitor (Y-27632; Tocris, 1254). Medium without the inhibitor was replaced daily until the cells reach 80-100% confluency ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Developmental Biology 2019Quote: ... From day 2 to day 4 the medium was additionally supplemented with BMP and TGFβ inhibitors (Noggin, Peprotech and SB431542, Tocris Bioscience). Treatment with MEK inhibitor (PD184352 ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Biochemistry 2022Quote: ... Positive clones were analyzed by Sanger sequencing with primers #3 and #4 (Integrated DNA Technologies, Supplementary Table S5) and degradation upon dTAG-13 (Tocris, 6605) treatment was confirmed by Western Blot by a-Chaf1a antibody (65) ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Neuroscience 2020Quote: ... 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester (KN-62; Tocris and HelloBio); D-AP5 (HelloBio) ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...
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bioRxiv - Physiology 2024Quote: ... Drugs were added from the following stock solutions: (2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboximide (WS-12, Tocris #3040, Bio-Techne Ltd, Abingdon, UK) 5 mM in ethanol ...
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bioRxiv - Neuroscience 2023Quote: ... we tested effects of an inhibitor (the spider toxin GsMTX 4; Tocris #4912 stock 50 μM in DMSO and the Piezo1 channel activator Yoda1 (Tocris 6586 10 and 20 uM, stock 20 mM in DMSO).