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Citations for Tocris :
501 - 550 of 692 citations for 6 chloro 5 iodonicotinic acid since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2023Quote: ... For drug treatments: AACOCF3 (selective phospholipase A2 inhibitor, Tocris #1462-5), CK666 (selective Arp2/3 inhibitor ...
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bioRxiv - Neuroscience 2023Quote: ... and Clozapine N-oxide dihydrochloride (CNO, 5 mg/kg, Tocris Bioscence) were dissolved in sterile 0.9% NaCl (saline) ...
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bioRxiv - Cell Biology 2023Quote: ... 0.1 mM 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt (Tocris) and 0.1 mM 3-Isobutyl-1-methylxanthine (Sigma-Aldrich) ...
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... The medium was supplemented with 5 μM Y27632 (TOCRIS, Cat.# 1254), a Rho-associated kinase inhibitor ...
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bioRxiv - Biochemistry 2023Quote: ... 5% CO2 with either DMSO or MLi-2 (Tocris; 2 μM) for 1 hour ...
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bioRxiv - Cell Biology 2023Quote: ... 0.1 mM 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt (Tocris) and 0.1 mM 3-Isobutyl-1-methylxanthine (Sigma-Aldrich) ...
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bioRxiv - Neuroscience 2024Quote: ... was dissolved in 5% DMSO (Tocris Bioscience, Cat#: 3176; Batch: 68A) containing PBS (Corning ...
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bioRxiv - Neuroscience 2024Quote: ... and D-2-amino-5-phosphonopetanoate (D-AP5, 50 μM; Tocris) were added to inhibit GABAergic or glutamatergic synaptic transmission ...
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bioRxiv - Neuroscience 2024Quote: ... and 50µM D-AP5 (D-2-amino-5-phosphonovalerate, Tocris 0106). Neurons were voltage clamped at -70mV ...
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Molecular Biology 2020Quote: ... kin28as strains and their controls were then grown to an OD600 of 0.8 and treated with 6 μM of 1-Naphthyl PP1 (NAPP1; Tocris Bioscience) for 15 min ...
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bioRxiv - Neuroscience 2022Quote: Primary microglia cells from C57Bl/6 J mice cultured in presence of CSF-1 were treated with Formoterol (10 ng/ml, cat # 1448, Tocris) or vehicle for 1 hour ...
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Pharmacology and Toxicology 2023Quote: ... 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy) phenyl]-2-pyridinyl]thio]-acetamide (BAY 60-6583; Tocris, 910487-58-0), 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide (2-Chloro-IB-MECA ...
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bioRxiv - Cancer Biology 2023Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Cell Biology 2021Quote: ... B/D medium was supplemented during submerged culture with 1 nM EC23 (light-stable retinoic acid receptor agonist; Tocris, Abingdon, UK). After confluence was reached ...
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Neuroscience 2023Quote: ... 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid (DQP 1105, 10 μM dissolved in DMSO; Tocris Bioscience), or 6-Cyano-7-nitroquinoxaline-2,3-dione disodium (CNQX ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141] ...
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bioRxiv - Cell Biology 2022Quote: ... The FFA2R antagonist CATPB ((S)-3-(2-(3-chlorophenyl)acetamido)-4-(4-(trifluoromethyl)-phenyl) butanoic acid) was from Tocris (Britsol, UK).
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bioRxiv - Neuroscience 2023Quote: ... Mice were injected intraperitoneally (i.p.) with 5.0mg/kg synthetic kainic acid (KA) dissolved in 0.9% saline (#7065, Tocris Bioscience, Bristol, United Kingdom). At twenty-minute intervals ...
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bioRxiv - Neuroscience 2021Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247; 5 μM SR-95531, Tocris, 1262; 1 μM CGP-55845, Tocris, 1248) were included in the recording solutions.
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bioRxiv - Neuroscience 2021Quote: ... The bath solution usually contained 6,7-dinitroquinoxaline-2,3-dione (DNQX, 10 µM) and D- aminophosphonovaleric acid (D-APV, 50 µM) to block ionotropic glutamate receptors (Tocris, Abingdon, United Kingdom). Patch electrodes had resistances of 4-6 MΩ when filled with KMeSO4- or CMeSO4-based internal solution (same as used in vivo) ...
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bioRxiv - Neuroscience 2019Quote: ... (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid (TFB-TBOA) was purchased from Tocris (Minneapolis, MN; Cat# 2532). All other chemicals were purchased from MilliporeSigma (Burlington ...
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bioRxiv - Immunology 2020Quote: ... These cells were then directed to become proepicardial cells by the addition of retinoic acid and WNT CHIR 99021 followed by TGFβ inhibition (SB431542, Tocris Bioscience 1614). Finally ...
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bioRxiv - Neuroscience 2023Quote: ... and cells were centrifuged at 200 rcf for 5 min and resuspended in N2B27 with the same supplements as on day 0 except for the removal of Y27632 and addition of all-trans retinoic acid (100 nM; Tocris, 0695/50) and SAG (500 nM ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Developmental Biology 2021Quote: ... NMP differentiation medium was supplemented with and 5 μM Y-27632 (Tocris).
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bioRxiv - Immunology 2019Quote: Cells were pre-treated with ML130 (5 μM; CID-1088438; Tocris, UK) 21 ...
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bioRxiv - Cell Biology 2019Quote: ... and 50µM D-(-)-2-amino-5-phosphonopentanoic (D-AP5 or APV; Tocris) buffered to pH 7.4 at 37°C ...
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bioRxiv - Cell Biology 2021Quote: Cells were treated with the actin inhibitor Cytochalasin-D (5 μM, Tocris), the Ezrin Inhibitor NSC668394 (50 μM ...
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bioRxiv - Developmental Biology 2022Quote: ... cells were refreshed with BPEL supplemented with 5 μM XAV939 (Tocris Bioscience) and 50 ng/ml VEGF (R&D Systems) ...
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bioRxiv - Neuroscience 2019Quote: ... and 5 µg/ml Bovine Serum Albumin) containing 4 µM CHIR99021 (Tocris), 3 µM SB431542 (Sigma) ...
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bioRxiv - Physiology 2021Quote: ... SN-401 (DCPIB, 5 mg/kg of body weight/day, Tocris, D1540), SN-403 ...
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bioRxiv - Developmental Biology 2021Quote: ... for 48 h followed by treatment with IWP2 (5 μM, Tocris, #3533) for an additional 48 h ...
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bioRxiv - Cell Biology 2020Quote: ... 5 mg/kg BW for 2,3-bis(4-Hydroxyphenyl)-propionitrile (DPN, Tocris), or vehicle ...
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bioRxiv - Cell Biology 2020Quote: ... media was changed to R/B-supplemented with 5 uM IWP2 (Tocris) for 48 hours ...
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bioRxiv - Immunology 2021Quote: ... and 5 ng/ml IL-2 (carrier-free; Tocris R&D Systems) added with cells ...
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bioRxiv - Bioengineering 2022Quote: ... and Nodal/Activin inhibitor (SB431542, Tocris, 1614, 5 µM, days 1-10). On day 2 ...
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bioRxiv - Neuroscience 2022Quote: ... or 20 μM 2-methylthyo-adenosine-5’-triphosphate (2-MeSATP, Tocris, 1062) over a 5-min period ...
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bioRxiv - Neuroscience 2023Quote: ... was used to block GluN2A and ifenprodil (5 µM, Tocris, Cat#0545) was used to block GluN2B ...
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bioRxiv - Neuroscience 2023Quote: ... The selective 5-HT2C receptor antagonist RS102221 (Tocris Bioscience, #1050, Minneapolis, MN) was dissolved in a 50% aCSF and 50% sterile saline solution and infused bilaterally into the aBNST at a dose of 0.5 µg per side [14][14] ...
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bioRxiv - Systems Biology 2023Quote: ... 10 μM Forskolin (Fisher, BP2520-5) and 100 μM IBMX (Tocris, 2845). Cells were maintained in incubators at 37°C ...
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bioRxiv - Bioengineering 2023Quote: ... and TGF-Beta inhibitor (SB431542, Tocris # 1614, 5 μM, days 0-7). Media was changed on days 3 and 6 and then every 2-3 days until day 7 ...
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bioRxiv - Genomics 2023Quote: ... 2,3-Bis(4-hydroxyphenyl)propionitrile (DPN, 5 mg/kg body weight, Tocris) and 4-(2-(3,5-dimethylisoxazol-4-yl)-1H-indol-3-yl)phenol (DIP ...
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bioRxiv - Pharmacology and Toxicology 2023Quote: A CC-chemokine receptor 5 (CCR5) antagonist (maraviroc; Tocris Biosciences, Bristol, UK) was dissolved in dimethyl sulfoxide and diluted with sterile PBS for further use ...