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Citations for Tocris :
301 - 346 of 346 citations for 6 Chloro N methoxy N methyl nicotinamide since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2023Quote: ... to block Na channels or 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, 10 µM, Tocris, Minneapolis, USA) to block AMPA/kainate receptors were introduced to the standard ACSF.
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bioRxiv - Neuroscience 2024Quote: ... IPSCs were recorded in the presence of 10µM CNQX (6-cyano-7-nitroquinoxaline-2,3-dione, Tocris 1045) and 50µM D-AP5 (D-2-amino-5-phosphonovalerate ...
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bioRxiv - Neuroscience 2023Quote: The AMPA receptor antagonist cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione; CNQX disodium salt; #1045; Tocris Biosciences) or 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione (DNQX disodium salt ...
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bioRxiv - Neuroscience 2024Quote: ... All networks received a 20-min 50 µM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX, in DMSO; Tocris, #0373) treatment on top of that ...
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Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentialsbioRxiv - Neuroscience 2021Quote: ... 4 or 8 μl of 6-OHDA (5 μg in 1 μl saline containing 0.1% ascorbic acid; Tocris, Bristol ...
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bioRxiv - Neuroscience 2019Quote: ... and NMDAR EPSCs were then isolated by addition of the AMPAR antagonist 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX, 10 µM; Tocris, Cat# 1044). NMDAR EPSCs were confirmed by addition of the NMDAR antagonist D,L-APV (20 µM ...
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bioRxiv - Immunology 2021Quote: ... cells were stimulated with HDM or the known AhR agonist FICZ (5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde, Tocris Bioscience ...
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bioRxiv - Molecular Biology 2021Quote: ... culture medium was replaced by E6 medium supplemented with 6 μM CHIR (Tocris, Bio-Techne, Abingdon, United Kingdom) to initiate differentiation (defined as day 0) ...
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bioRxiv - Neuroscience 2020Quote: ... to allow outside-out patch recording and 30 μM 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX; Tocris, Cat#1044) was added to media post-transfection to avoid AMPAR-mediated toxicity.
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Pathogenic CD8 T cell responses are driven by neutrophil-mediated hypoxia in cutaneous leishmaniasisbioRxiv - Immunology 2023Quote: ... the sections were counter-stained with the nuclear probe 4’,6-diamino-2-phenylindole (DAPI, Biotechne-Tocris, UK). Slides were covered with Prolong™ Gold Antifade Mountant (Invitrogen ...
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bioRxiv - Neuroscience 2021Quote: ... The resulting cell pellet was broken up and resuspended in 1ml E8 media by 1000ul pipette and distributed on a Geltrex coated 6 well plate with E8 and 10µM ROCK inhibitor (Y-27632 dihydrochloride, Tocris) for 24 hours ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 1μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 3μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Cell Biology 2021Quote: ... or the AMPA-iGluR specific inhibitor 2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX, cat. num. 373, Tocris). Drugs were dissolved in ESC complete media (no 2i ...
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bioRxiv - Neuroscience 2022Quote: ... were recorded during the application of the competitive AMPA/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 20 μM, Tocris) and the selective NMDA receptor antagonist amino-5-phosphonopentanoic acid (AP5 ...
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bioRxiv - Neuroscience 2019Quote: ... 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (“NBQX”, 100 mM in DMSO, Tocris Cat No 0373); D-2-amino-5-phosphonovalerate (“D-AP5” ...
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bioRxiv - Molecular Biology 2022Quote: ... 6 replicates of each condition were treated with DMSO or 100 nM dTAG13 (Tocris Bioscience, Fisher Scientific 66-055) for 2 hours ...
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bioRxiv - Neuroscience 2023Quote: ... slices were incubated in recording ACSF supplemented with 5 μM 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, Tocris, 1045) and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Neuroscience 2022Quote: ... drugs were bath applied at the following concentrations (in μM): 10 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX, Tocris), 50 D-2-amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Cell Biology 2022Quote: ... Neuroectoderm was induced for 6 days in CDM-BSA supplemented with 12ng/ml FGF2 and 10μM SB431542 (Activin/Nodal/TGFβ inhibitor; Tocris), as previously described34 ...
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bioRxiv - Immunology 2023Quote: Co-culture assays: thymocytes were isolated from untreated C57BL/6 mice and incubated with Nigericin (10 µM, Tocris, 4312) and LPS (1 ng/ml ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... were recorded at −70mV in presence of 20□μM CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione disodium, an AMPA receptor antagonist, Tocris) and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid ...
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bioRxiv - Cell Biology 2024Quote: ... Cultures were passaged every 6 days and kept in a cycle of 3 days in 5μM ROCK inhibitor (Y-27632 dihydrochloride; Tocris), 3 days in the absence of rock inhibitor ...
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Molecular Biology 2020Quote: ... kin28as strains and their controls were then grown to an OD600 of 0.8 and treated with 6 μM of 1-Naphthyl PP1 (NAPP1; Tocris Bioscience) for 15 min ...
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bioRxiv - Neuroscience 2021Quote: ... 10 μM NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) and 50 μM AP-5 (Tocris Bioscience, UK) were applied in the bath to block excitatory synaptic responses.
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bioRxiv - Neuroscience 2022Quote: Primary microglia cells from C57Bl/6 J mice cultured in presence of CSF-1 were treated with Formoterol (10 ng/ml, cat # 1448, Tocris) or vehicle for 1 hour ...
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Pharmacology and Toxicology 2023Quote: ... 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy) phenyl]-2-pyridinyl]thio]-acetamide (BAY 60-6583; Tocris, 910487-58-0), 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide (2-Chloro-IB-MECA ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 μM 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531; GABAA receptor antagonist, all from Tocris). The resting membrane potential was measured after whole-cell configuration was achieved ...
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bioRxiv - Cancer Biology 2023Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Neuroscience 2022Quote: ... was inserted into the guide cannula and a Hamilton Syringe was used to administrate 1 μL of 2 mM pyridoxalphosphate-6-azophenyl-2’,4’-disulfonic acid (PPADS, Tocris, 0625), 1.5 μg/μL S961 (Phoenix Pharmaceuticals ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 µM 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531;GABAA receptor antagonist; all from Tocris Bioscience).
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Neuroscience 2022Quote: ... food was removed for 3 hours (3 pm – 6 pm) and mice received either vehicle or CCK-8s (20 μg/kg BW; i.p.; Tocris, St. Louis, USA) injection at dark onset (6 pm ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Microbiology 2024Quote: To investigate the impact of gallein (3’,4’,5’,6’-Tetrahydroxyspiro[isobenzofuran-1(3H),9’- (9H)xanthen]-3-one) (Cat#3090, Tocris, Minneapolis, MN) and/or INH on Mtb growth ...
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bioRxiv - Neuroscience 2021Quote: ... 3 or 6 μg/hemisphere of LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience, Oakville, Ontario), in a counterbalanced ...
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bioRxiv - Neuroscience 2022Quote: ... dissociated hiPSCs were plated at 1×104 cells/cm2 into 6-well plates in the presence of 10 µM ROCK inhibitor (Y-27632, Tocris Bioscience, Bristol, UK). Cortical and hypothalamic differentiation took place on a substrate of geltrex (1:100 ...
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
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bioRxiv - Biochemistry 2024Quote: ... The filtrate was diluted two times the volume with buffer UA (8 M urea [Acros Organics, CAS No. 57-13-6], 50 mM sodium acetate [Tocris CAS No. 127-09-3], pH 4). This was loaded onto a HiPrep SP HP 16/10 (Cytiva ...