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Citations for Tocris :
351 - 400 of 530 citations for 6 Chloro 4 ethoxy nicotinic acid since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2023Quote: The AMPA receptor antagonist cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione; CNQX disodium salt; #1045; Tocris Biosciences) or 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione (DNQX disodium salt ...
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bioRxiv - Neuroscience 2024Quote: ... All networks received a 20-min 50 µM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX, in DMSO; Tocris, #0373) treatment on top of that ...
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bioRxiv - Neuroscience 2024Quote: ... IPSCs were recorded in the presence of 10µM CNQX (6-cyano-7-nitroquinoxaline-2,3-dione, Tocris 1045) and 50µM D-AP5 (D-2-amino-5-phosphonovalerate ...
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bioRxiv - Neuroscience 2019Quote: ... (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3’,2’,1’-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester (K252a, 200 nM) (Tocris), 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one (DHF ...
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bioRxiv - Developmental Biology 2020Quote: ... and FGF2 (100 ng/ml, R&D) in the presence or absence of retinoic acid (0.1 µM, Tocris). For paraxial mesoderm differentiation ...
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bioRxiv - Neuroscience 2023Quote: Susceptibility to seizures induced by the chemoconvulsant kainic acid (abbreviated as KA, Cat #0222, Tocris Bioscience, Minneapolis, MN) was assessed in B6 and F1D2 WT and Scn2aE/+mice of both sexes P41-44 days of age ...
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bioRxiv - Neuroscience 2021Quote: ... 4- aminopyridine (Tocris Bioscience, 50 µM, 5 min-2hrs or 20hrs), AP5 (Tocris Bioscience ...
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bioRxiv - Neuroscience 2020Quote: ... and the aquaporin-4 channel inhibitor TGN-020 (Tocris; 100 μM) were co-applied (n=16) ...
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bioRxiv - Physiology 2021Quote: ... and/or 4) 100 nM ONO-8130 (Tocris Bioscience, Bristol, UK). In the latter two conditions ...
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bioRxiv - Neuroscience 2023Quote: ... and 1 mM (S)-α-methyl-4-carboxyphenylglycine ((S)-MCPG) (Tocris). Neurons were field stimulated with 1 ...
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bioRxiv - Neuroscience 2023Quote: ... 50 µM CGP54626 Hydrochloride (1088/10, TOCRIS, CAS 149184-21-4), 200 µM (low dose ...
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bioRxiv - Neuroscience 2019Quote: ... and NMDAR EPSCs were then isolated by addition of the AMPAR antagonist 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX, 10 µM; Tocris, Cat# 1044). NMDAR EPSCs were confirmed by addition of the NMDAR antagonist D,L-APV (20 µM ...
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bioRxiv - Immunology 2021Quote: ... cells were stimulated with HDM or the known AhR agonist FICZ (5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde, Tocris Bioscience ...
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bioRxiv - Molecular Biology 2021Quote: ... culture medium was replaced by E6 medium supplemented with 6 μM CHIR (Tocris, Bio-Techne, Abingdon, United Kingdom) to initiate differentiation (defined as day 0) ...
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bioRxiv - Neuroscience 2020Quote: ... to allow outside-out patch recording and 30 μM 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX; Tocris, Cat#1044) was added to media post-transfection to avoid AMPAR-mediated toxicity.
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bioRxiv - Neuroscience 2022Quote: ... 3,5-dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide-hydrochloride (ML218 or ml) was purchased from TOCRIS and initially dissolved at 50 mM in DMSO ...
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bioRxiv - Physiology 2023Quote: ... animals either received vehicle (1 µl DMSO; n = 6) or the DREADD ligand clozapine n-oxide (CNO, Tocris; 0.1 mg/µl DMSO ...
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bioRxiv - Neuroscience 2021Quote: ... d-2-Amino-5-phosphonovaleric acid (d-AP5, 50µM) and the sodium (Na+) channel blocker tetrodotoxin (TTX, 1 µM Tocris). Individual traces (5 sec duration ...
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bioRxiv - Neuroscience 2019Quote: ... To block NMDA receptors we used D- (-)-2-Amino-5-phosphonopentanoic acid (D-AP5, Tocris, 10 μM final concentration). To block glycinergic inhibition ...
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bioRxiv - Biochemistry 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy] butanoic acid (DCPIB) was purchased from Tocris Bioscience and reconstituted to 50 mM in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... 20 μM 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 20 μM D-(-)-2-amino-5-phosphopentanoic acid (D-AP5) (Tocris Bioscience) to block glycine- ...
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bioRxiv - Neuroscience 2020Quote: ... CGP 55845 ((2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl) phosphinic acid hydrochloride) and GRK2i were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2021Quote: ... our early pilot experiments assessed the impact of varying doses of Kainic Acid Monohydrate (KA, 0222, Tocris, Minneapolis, MN) on outcomes ...
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bioRxiv - Biochemistry 2021Quote: ... were recorded at 32°C in an interface-type chamber (perfusion rate 4.5 mL per minute) and elicited by applying kainic acid (100 nmol L-1, Tocris). The oscillations were stabilized for 20 min before any recordings ...
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bioRxiv - Biochemistry 2021Quote: Guanine unfolding experiments were performed by fluorescent dye assay using bis-ANS (4,4’-dianilino-1,1’-binaphthyl-5,5’-disulfonic acid, Tocris, Bristol, UK) as described previously(21 ...
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bioRxiv - Immunology 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid (DCPIB, 1540) was from Tocris. NS3728 and NBC19 were made at the University of Manchester.
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bioRxiv - Neuroscience 2021Quote: ... The resulting cell pellet was broken up and resuspended in 1ml E8 media by 1000ul pipette and distributed on a Geltrex coated 6 well plate with E8 and 10µM ROCK inhibitor (Y-27632 dihydrochloride, Tocris) for 24 hours ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 1μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Neuroscience 2020Quote: ... and re-plated at 1:6 ratio on Matrigel-coated plate in neural medium supplemented with 3μM CHIR99021 (Tocris), 2μM DMH1 (Tocris) ...
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bioRxiv - Cell Biology 2021Quote: ... or the AMPA-iGluR specific inhibitor 2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX, cat. num. 373, Tocris). Drugs were dissolved in ESC complete media (no 2i ...
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bioRxiv - Neuroscience 2022Quote: ... were recorded during the application of the competitive AMPA/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 20 μM, Tocris) and the selective NMDA receptor antagonist amino-5-phosphonopentanoic acid (AP5 ...
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bioRxiv - Neuroscience 2019Quote: ... in the presence of the mGluR5 antagonist 2-methyl-6 (phenylethynyl)-pyridine (MPEP, 25 μM; Tocris Bioscience, Bristol, UK). Inhibitors were applied concomitantly from 30 min before to 30 min after DHPG/MPEP treatment ...
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bioRxiv - Neuroscience 2019Quote: ... 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (“NBQX”, 100 mM in DMSO, Tocris Cat No 0373); D-2-amino-5-phosphonovalerate (“D-AP5” ...
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bioRxiv - Neuroscience 2021Quote: ... The mGluR5 specific negative allosteric modulator MPEP hydrochloride (2-Methyl-6-(phenylethynyl)pyridine hydrochloride) was purchased from Tocris (1212) and administered to brain slices at 30 μM by bath perfusion ...
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bioRxiv - Molecular Biology 2022Quote: ... 6 replicates of each condition were treated with DMSO or 100 nM dTAG13 (Tocris Bioscience, Fisher Scientific 66-055) for 2 hours ...
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bioRxiv - Neuroscience 2023Quote: ... slices were incubated in recording ACSF supplemented with 5 μM 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, Tocris, 1045) and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Neuroscience 2022Quote: ... drugs were bath applied at the following concentrations (in μM): 10 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX, Tocris), 50 D-2-amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Cell Biology 2022Quote: ... Neuroectoderm was induced for 6 days in CDM-BSA supplemented with 12ng/ml FGF2 and 10μM SB431542 (Activin/Nodal/TGFβ inhibitor; Tocris), as previously described34 ...
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bioRxiv - Immunology 2023Quote: Co-culture assays: thymocytes were isolated from untreated C57BL/6 mice and incubated with Nigericin (10 µM, Tocris, 4312) and LPS (1 ng/ml ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... were recorded at −70mV in presence of 20□μM CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione disodium, an AMPA receptor antagonist, Tocris) and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid ...
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bioRxiv - Cell Biology 2024Quote: ... Cultures were passaged every 6 days and kept in a cycle of 3 days in 5μM ROCK inhibitor (Y-27632 dihydrochloride; Tocris), 3 days in the absence of rock inhibitor ...
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Neuroscience 2021Quote: ... Glutamatergic neurons were identified by their characteristic EPSC time course and by sensitivity of EPSC to application of glutamate receptor antagonist kynurenic acid (Tocris). Synaptic currents were acquired at 10 kHz using pClamp 10.2 software (Molecular Devices ...
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bioRxiv - Neuroscience 2021Quote: ... and GluN2BGC−/− mice (P40 – P60) were stereotactically injected with 50 nl of 20 mM solution of kainic acid (Tocris / Biotechne) in 0.9 % NaCl to the left CA1 area of the dorsal hippocampus (AP −1.8 mm ...
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bioRxiv - Genomics 2021Quote: ... neurons were made quiescent for 2 hours with 100 μM D-2- amino-5-phosphonopentanoic acid (D-AP5; Tocris #0106) and 1 μM tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Neuroscience 2019Quote: ... Specific blockade of GABA-B receptors was performed by wash in of 10 µM CGP 55845 hydrochlorid [(2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride] (Tocris Bioscience) for 20 minutes.
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...
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bioRxiv - Neuroscience 2022Quote: Astrocytes grown in 6-well plates were refreshed with glial maintenance media or glial maintenance media supplemented with 100 μM L-Glutamic Acid (Tocris) for 3 h ...
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bioRxiv - Cell Biology 2023Quote: ... (Optopharma Ltd.) and 20 nM for 1-Oleoyl lysophosphatidic acid sodium salt (LPA) (5 mM stock dissolved in water) (Tocris). As controls ...