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Citations for Tocris :
701 - 750 of 1639 citations for 6 Chloro 2 methyl 1 2 4 triazolo 4 3 b pyridazin 3 2H one since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Genetics 2019Quote: ... 0.055mM 2-mercaptoethanol and 1ug/ml Insulin) plus 1.5uM Dorsomorphin (Tocris Bioscience) and 10uM SB431542 (Stemgent) ...
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bioRxiv - Neuroscience 2021Quote: ... and 50 µM D-(-)-2-amino-5-phosphonopentanoic acid (AP5, Tocris Bioscience) were added to the bath to block glutamatergic currents ...
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bioRxiv - Developmental Biology 2021Quote: ... GANT61, a Gli1/2 inhibitor (Gli-I, #3191) was purchased from Tocris Bioscience (Bio-Techne ...
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bioRxiv - Immunology 2021Quote: ... and 5 ng/ml IL-2 (carrier-free; Tocris R&D Systems) added with cells ...
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bioRxiv - Neuroscience 2022Quote: ... D-2-Amino-5-phosphonopentanoic acid (D-AP5, 25 μM; Tocris #0106). These were stored as stock aliquots and diluted in fresh aCSF to their final concentration the day of recording ...
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Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathybioRxiv - Genetics 2022Quote: ... medium was changed to RPMI-Insulin with 2 μM Wnt-C59 (Tocris). At day 5 and 7 ...
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bioRxiv - Bioengineering 2023Quote: ... media was exchanged to basal media supplemented with 2 μM IWP2 (Tocris), 10 μM SB431542 and 3 μM Dorsomorphin (only for WT and NME5mut ...
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bioRxiv - Cell Biology 2023Quote: ... The concentrations used for the inhibitors are: 2 μM Latrunculin A (Tocris Bioscience ...
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bioRxiv - Physiology 2023Quote: ... LY2584702 (2 μM, Key Organics, UK) and Torin1 (25 nM, Tocris, UK) were also dissolved in DMSO ...
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bioRxiv - Neuroscience 2024Quote: ... doxycycline (2 µg/mL) and 10 µM Y-27632 (DIV0 only; Tocris) which was exchanged daily ...
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bioRxiv - Cell Biology 2024Quote: ... Cells were treated with the NHEJ inhibitors NU7441 (2 μM; Tocris Bioscience) and SCR7 (1 μM ...
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bioRxiv - Cell Biology 2024Quote: ... and Yoda1 (Piezo1/2 activator; cat no. 5586) were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2019Quote: Hippocampal NA denervation was performed using the NA axon specific neurotoxin DSP-4 (Tocris, Ellisville, MO), known to cause terminal retrograde degeneration by targeting the NE uptake system (Jaim-Etcheverry and Zieher ...
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bioRxiv - Neuroscience 2022Quote: ... we used 100 μM 4-methoxy-7-nitroindolinyl-caged-L-glutamte (MNI-glutamate, Tocris, UK, 1490) with 10 μM glycine ...
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bioRxiv - Neuroscience 2023Quote: Glutamate was photolysed from MNI-Glutamate (4-Methoxy-7-nitroindolinyl-caged-L-glutamate; Tocris Biotechne, UK) with a 405 nm laser (Obis ...
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bioRxiv - Neuroscience 2024Quote: ... a non-selective opioid antagonist (0.5 mg/24 hours over 4 weeks, Tocris, Cat# 0599/100) or vehicle solution via an ALZET mini osmotic pump (Model 1004 ...
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bioRxiv - Neuroscience 2024Quote: 6-hydroxydopamine (Tocris) injections were performed in WT mice at 8-9 weeks of age ...
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bioRxiv - Neuroscience 2020Quote: ... the GABAA channel blocker Picrotoxin (50 µM) or the GABAB antagonist CGP-54626 (3 µM) (Tocris Bioscience, Minneapolis, MN) was bath applied 80 min prior to HFS ...
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bioRxiv - Developmental Biology 2020Quote: ... day 3 NMP-like cell cultures were treated with Accutase and replated at a density of 63,000 cells//cm2 in N2B27 supplemented with CHIR99021 (3 µM, Tocris), FGF2 (100 ng/ml ...
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Sexual dimorphism of insular cortex function in persistent alcohol drinking despite aversion in micebioRxiv - Neuroscience 2023Quote: ... The causal role of aIC or pIC glutamatergic neurons on drinking was tested after injection of CNO (i.p. 3 mg/kg in NaCl, Tocris) or vehicle 30 minutes before the last session of binge (day 18) ...
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bioRxiv - Neuroscience 2019Quote: ... and 50 μM D,L-2-amino-5-phosphonovaleric acid / AP5 (Tocris Bioscience). Coverslips were mounted in an RC-21BRFS chamber (Warner Instruments ...
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bioRxiv - Neuroscience 2019Quote: ... and 50 µM D-2-amino-5-phosphonovaleric acid (D-AP-5; Tocris) to isolate synaptic inhibitory transmission ...
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bioRxiv - Neuroscience 2021Quote: The following drugs were used: 20 µM WIN 55212-2 (WIN; Tocris Bioscience), 100 µM 2-AG (Tocris Bioscience) ...
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bioRxiv - Neuroscience 2021Quote: ... neurons were stimulated in the presence of 2 μM GSK3 inhibitor (CT99021, Tocris) and placed in fresh basal medium containing 2 μM GSK3 inhibitor for 10 min at 37°C and 5% CO2 ...
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bioRxiv - Neuroscience 2023Quote: ... and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV, Tocris, 0106) to block glutamatergic inputs ...
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bioRxiv - Neuroscience 2023Quote: ... either saline (0.4%) or clozapine N-oxide (CNO, TOCRIS Bioscience, 2 mg/kg) was injected i.p ...
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bioRxiv - Cancer Biology 2022Quote: ... the TGF-beta/Activin/Nodal inhibitor SB-431542 (2 μM, Cat# 1614, Tocris), CHIR99021 (1 μM ...
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bioRxiv - Neuroscience 2023Quote: ... DL-2- amino-5-phosphono-pentanoic acid (AP5; 50 µM; Tocris, Item# 0105), 4-Aminopyridine (4- AP ...
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bioRxiv - Neuroscience 2023Quote: ... CNQX and D(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) were from Tocris Biosciences ...
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bioRxiv - Neuroscience 2023Quote: ... D-2-amino-5-phosphonopentanoate (D-AP5, Tocris, Ellisville, MO, Cat. No. 0106 ), and Dizocilpine ((+)-MK801 ...
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bioRxiv - Neuroscience 2023Quote: ... NMDAR antagonist D-(-)-2-Amino-5-phosphonopentanoic acid (D-APV 50µM, Tocris-0106) and tetrodotoxin (TTX ...
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bioRxiv - Cancer Biology 2023Quote: Cells were incubated for six days with Lalistat (Lalistat 2, TOCRIS, Bristol, UK) in a 6-well plate ...
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bioRxiv - Bioengineering 2024Quote: ... CDM was supplemented with 2 μM Wnt-C59 (Tocris Bioscience, cat. no. 5148). Following CDM was changed every two days ...
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bioRxiv - Neuroscience 2023Quote: ... GluN2B was inhibited by 2 µM RO 25-6981 (Tocris Bioscience, Bristol, UK) (Abrahamsson et al. ...
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bioRxiv - Neuroscience 2024Quote: ... mice were allowed to recover for 2 weeks before administration of CNO (Tocris). CNO was dissolved in drinking water ...
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bioRxiv - Biochemistry 2024Quote: ... and ligands (LXA4 and 15-oxo-LXA4-Me at 2 μM, WKYMVm (Tocris) at 5 μM) ...
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bioRxiv - Neuroscience 2021Quote: ... SR95531 (gabazine) and 4-methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate) were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Animal Behavior and Cognition 2022Quote: ... Either α-cyano-4-hydroxycinnamate (CHC, daily i.p. injection of 15 mg/kg, Tocris Bioscience, Bristol, UK) plus metformin (Met ...
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bioRxiv - Physiology 2023Quote: ... Reagents added to cell culture media are as follows: 250 μM 4-octyl itaconate (Tocris Bioscience, 6662), 4μM Etomoxir (Sigma ...
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bioRxiv - Neuroscience 2020Quote: ... slices were equilibrated for 10 minutes while being continuously superfused at room temperature with oxygenated aCSF at 1-2 ml/min containing picrotoxin (50 μM, Tocris Bioscience, MO, USA) to block GABAA receptor-mediated inhibitory responses.
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bioRxiv - Neuroscience 2024Quote: ... a third group of animals were treated as those in group 2 with the addition of CB1 receptor antagonist AM251 (1 µM) (Tocris Bioscience, Bristol, UK). After 8 DIV ...
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bioRxiv - Immunology 2020Quote: ... cathepsin B inhibitor MDL 28170 (Tocris Bioscience) at 0.1 μM ...
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bioRxiv - Systems Biology 2022Quote: ... cells were treated with Pladienolide B (Tocris) 24 hours prior to irradiation ...
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bioRxiv - Neuroscience 2020Quote: ... 0.9% w/v) and 6-OHDA HCl powder (6-hydroxydopamine hydrochloride from Sigma or 6-OHDA hydrobromide from Tocris) was then dissolved to produce a final 6-OHDA concentration of 4.44 mg/ml ...
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Neuroscience 2020Quote: ... placed in an aCSF-filled borosilicate glass pipette (3-5 MΩ) in the presence of 6,7-Dinitroquinoxaline-2,3-dione (DNQX; 10 μM; Tocris #14A/166549).
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bioRxiv - Neuroscience 2022Quote: ... animals were treated with the selective positive allosteric modulator (PAM) of mGluR5 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide (CDPPB; Tocris, UK) that was diluted in saline solution containing 5-10% final concentration of DMSO and polyethylene glycol 400 (DMSO ...
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bioRxiv - Neuroscience 2021Quote: ... Hox propagation was initiated by activation of Wnt signaling using NMP media comprised of E6 medium supplemented with 200 ng/mL FGF8b and 3 μM CHIR99021 (Tocris). This constitutes the “Hox timepoint” of 0hrs ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... 0.3 or 1 mg/kg of the mGlu2/3 receptor agonist LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience ...
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bioRxiv - Neuroscience 2022Quote: ... 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolol[1,5-a]pyrimidin-3-yl]phenol (PHTPP, 10 μM dissolved in 10% DMSO, TOCRIS, Minneapolis, MN), microinjected bilaterally into the CeA (0.5 μL over one minute with a one-minute wait post-infusion ...