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Citations for Tocris :
501 - 550 of 590 citations for 6 CHLOROBENZO D ISOXAZOLE 3 CARBONITRILE since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2022Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) (both from Tocris, Bristol, UK) to block recurrent glutamatergic signaling.
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2023Quote: ... all buffers and solutions used during the process (from animal perfusion to sorted cells flash freezing) were supplemented with a cocktail composed of Actinomycin D (3μM, Tocris #1229/10), Anisomycin (100 μM ...
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Cell Biology 2021Quote: ... Calcium-like peptide 2 (CALP2) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) were obtained from Tocris (Minneapolis, MN). CaM kinase II and calcineurin inhibitors ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Neuroscience 2021Quote: ... free microdialysis probes (n=3) were inserted into a solution of 100nM adenosine (Tocris Biosciences, Bristol, U.K.) in Ringer’s Solution ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...
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bioRxiv - Neuroscience 2021Quote: ... To inhibit PAK1-3 cells were preincubated with the small molecule pyridopyrimidinone inhibitor FRAX 486 (Tocris, Inc.) [26] at 500 nM in 0.01% DMSO for 30 min ...
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bioRxiv - Neuroscience 2020Quote: ... EPSCs were induced in the presence of the competitive AMPA receptor antagonist NBQX (3 μM, Tocris Bioscience). Paired-Pulse stimulation for excitatory autapses was assessed by the induction of 2 action potentials with an interstimulus interval of 25 ms ...
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bioRxiv - Neuroscience 2020Quote: ... 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydrochloride (SKF-96365; 1147, Tocris) in ddH20 ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: PAOPA ((3R)-2-Oxo-3-[[(2S)-2-Pyrrolidinylcarbonyl]amino]-1-pyrrolidineacetamide) was acquired from Tocris (Minneapolis, MN). (-)Quinpirole HCl and dopamine HCl were acquired from Sigma-Aldrich (St ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... by timed use of small molecule GSK 3 inhibitors and Wnt/β-catenin signal pathway inhibitors (Tocris). Twenty-four hours prior to cryopreservation ...
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bioRxiv - Molecular Biology 2019Quote: ... or washed three times in water and stained with 10 μM (5Z)-5-[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4H-imidazol-4-one (DFHBI-1T)(Tocris) in 50 mM KCl ...
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Prelimbic proBDNF facilitates memory destabilization by regulation of neuronal function in juvenilesbioRxiv - Neuroscience 2022Quote: ... 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP; 32 ng/μL; Cat#01773, Tocris Bioscience), NVP-AAM077 (0.8 ng/μL ...
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bioRxiv - Synthetic Biology 2022Quote: (5Z)-5[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4H-imidazol-4-one (DFHBI-1T) was purchased from Tocris Bio-techne ...
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bioRxiv - Neuroscience 2022Quote: ... Chemical LTD was induced by 3 min of NMDA (50 µM; Tocris Biosciences, catalog no. 0114/50) stimulation and washout (Shehata et al. ...
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bioRxiv - Biophysics 2023Quote: ... were maintained in serum-free N2B27 medium containing 2i (1 mM PD0325901and 3 mM CHIR99021, both Tocris) and LIF (10 mg/ml ...
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bioRxiv - Neuroscience 2024Quote: ... EPSCs were induced in the presence of the competitive AMPA receptor antagonist NBQX (3 µM, Tocris Bioscience). Paired-Pulse stimulation for excitatory autapses was assessed by the induction of 2 action potentials with an interstimulus interval of 20 ms ...
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bioRxiv - Neuroscience 2020Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) to block glutamatergic signaling (both from Tocris, Bristol, UK). Experiments involving tetrodotoxin (TTX ...
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bioRxiv - Immunology 2019Quote: ... and grown in B cell growth media to 80% confluence before being treated for 4h with 5μg/ml mitomycin C (Tocris, R&D Systems). Monolayers of growth arrested cells were washed 3 times with PBS ...
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bioRxiv - Neuroscience 2022Quote: ... these experiments were performed in the presence of AMPA and NMDA receptor blockade (10 µM NBQX and 50 µM D-AP5 respectively; Tocris, Bristol, UK). To isolate excitatory currents ...
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bioRxiv - Neuroscience 2023Quote: Adherent human iPSCs were grown to near confluence before the differentiation to heterogenous spinal/hindbrain neurons was initiated by changing the media for two days to media d1-2 (200 nM LDN193189 [Tocris, 6053], 10 µM SB431542 [Tocris, 1614], 25 ng/mL SHH-C25II [R&D Systems, 464-SH-025], 250 nM Purmorphamine [Tocris, 4551] ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2022Quote: ... dissociated hiPSCs were plated at 1×104 cells/cm2 into 6-well plates in the presence of 10 µM ROCK inhibitor (Y-27632, Tocris Bioscience, Bristol, UK). Cortical and hypothalamic differentiation took place on a substrate of geltrex (1:100 ...
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bioRxiv - Neuroscience 2019Quote: ... (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3’,2’,1’-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester (K252a, 200 nM) (Tocris), 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one (DHF ...
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bioRxiv - Neuroscience 2019Quote: N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM251, 3µM) (Tocris) was dissolved in ethanol and then added in the external solution at a final concentration of ethanol of 0.015% ...
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bioRxiv - Developmental Biology 2021Quote: ... paraxial mesoderm (1 day; 20 ng/ml FGF2, 3 µM CHIR99021, 2 µM SB505124 [cat. num. 3263; Tocris Bioscience ...
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bioRxiv - Neuroscience 2021Quote: ... the group 2/3 mGluR agonist (DCG-IV) and MNI-glutamate for uncaging experiments were purchased from Tocris Bioscience ...
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bioRxiv - Molecular Biology 2022Quote: Parental A549 cells were fixed with 4% paraformaldehyde following 3-hour treatment with poly I:C (2.0 μg/mL, Tocris), LPS (1.0 μg/mL ...
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bioRxiv - Cell Biology 2023Quote: ... Neurosensor 510 (7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde) was purchased from (Tocris).
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bioRxiv - Physiology 2024Quote: ... 4-(3-chloro-pyridin-2-yl)-piperazine-1-carboxylic acid (4-tert-butyl-phenyl)-amide (BCTC, Tocris #3875) 10 mM in DMSO ...
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
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bioRxiv - Bioengineering 2023Quote: ... The supernatant was aspirated and the pellet re-suspended in fresh E8 medium supplemented with 10 µM ROCK inhibitor (Tocris R&D Systems). Re-suspended cells were seeded at a density between 7,500 – 12,500 cells / cm2 on fresh Matrigel-coated plates (Day – 3) ...
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bioRxiv - Cell Biology 2020Quote: ... Cyclopiazonic-acid (CPA) and 2’(3’)-O-(4-Benzoylbenzoyl)adenosine-5’-triphosphate (BzATP) triethylammonium salt was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2020Quote: ... CGP 55845 ((2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl) phosphinic acid hydrochloride) and GRK2i were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2020Quote: ... the GABAA channel blocker Picrotoxin (50 µM) or the GABAB antagonist CGP-54626 (3 µM) (Tocris Bioscience, Minneapolis, MN) was bath applied 80 min prior to HFS ...
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bioRxiv - Neuroscience 2019Quote: ... and substracted from background noise by detecting events in the last 4 seconds of 5 EPSCs at 0.2 Hz in 3 mM NBQX (Tocris) in extracellular solution.
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bioRxiv - Neuroscience 2021Quote: ... AM 251 (N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide) from Tocris and ...
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bioRxiv - Physiology 2021Quote: ... resiniferatoxin and 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide (BCTC) were purchased from Tocris Bioscience or Adooq Bioscience and stock solutions were prepared in EtOH at 1 M and 100 mM ...
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bioRxiv - Developmental Biology 2020Quote: ... day 3 NMP-like cell cultures were treated with Accutase and replated at a density of 63,000 cells//cm2 in N2B27 supplemented with CHIR99021 (3 µM, Tocris), FGF2 (100 ng/ml ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... N,N’-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride (IT1t) was purchased from Tocris (United Kingdom). Bovine serum albumin ...
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bioRxiv - Neuroscience 2021Quote: ... N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM251, 5 µM, Tocris); Tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2021Quote: ... 4-(4-,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl) benzeneacetamide (GW627368X 3 µM, Tocris); 6-Isopropoxy-9-xanthone-2-carboxylic acid (AH6809 ...
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bioRxiv - Neuroscience 2020Quote: ... all electrophysiological recordings were performed in the presence of picrotoxin (100μM) and 3-((R)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP; 10μM; Tocris Bioscience), and a cut was made between CA3 and CA1 regions to prevent the propagation of epileptiform activity ...
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bioRxiv - Neuroscience 2022Quote: ... injected with saline (control) or a range of doses (0.3, 1, 3, or 10mg/kg) of (R)-CPP (Tocris Bioscience ...
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bioRxiv - Microbiology 2023Quote: ... Monolayers were then treated with increasing doses (0, 0.5, 1, 3, 5, 7, 10, 20 μM) of Ro 08-2750 (TOCRIS) dissolved in DMSO ...
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bioRxiv - Neuroscience 2023Quote: Pharmacological inhibition of AQP4 was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience, UK). Unless otherwise stated ...
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bioRxiv - Neuroscience 2023Quote: ... anisomycin and N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM-251) were purchased from Tocris Bioscience ...
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Sexual dimorphism of insular cortex function in persistent alcohol drinking despite aversion in micebioRxiv - Neuroscience 2023Quote: ... The causal role of aIC or pIC glutamatergic neurons on drinking was tested after injection of CNO (i.p. 3 mg/kg in NaCl, Tocris) or vehicle 30 minutes before the last session of binge (day 18) ...