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Citations for Tocris :
401 - 450 of 1519 citations for trans 2 2 4 Methoxyphenyl 2 oxoethyl cyclohexane 1 carboxylic acid since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2021Quote: We inhibited LRRK2 kinase activity with the selective LRRK2 inhibitor MLi-2 (Tocris 5756). MLi-2 has low solubility in water ...
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bioRxiv - Genomics 2021Quote: ... followed by 2 uM of the Wnt signaling inhibitor Wnt-C59 (5148, Tocris Bioscience). Cells start to spontaneously beat between days 7-10 ...
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bioRxiv - Neuroscience 2024Quote: ... and 30 μm d-2-amino-5-phosphonovalerate (d-AP5) (NMDA receptor antagonist, Tocris).
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bioRxiv - Cancer Biology 2024Quote: ... 20 µM PAR-2 antagonist FSLLRY-NH2 (#4751, TOCRIS/Bio-Techne, Minneapolis, MN, USA) or 0.5 µM cysteine protease inhibitor E64 (#324890 ...
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bioRxiv - Cell Biology 2024Quote: ... + 10 μM Tranylcypromine (2-PCPA) HCl (DMSO; Selleckchem S4246) + 20 μM Forskolin (DMSO; Selleckchem S2449) + 1 μM Ch 55 (DMSO; Tocris 2020) + 5 μM EPZ004777 (DMSO ...
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bioRxiv - Physiology 2023Quote: ... the cell medium was replaced with the experimental medium (2 ml/well) consisting of DMEM containing 1 nM of 1,25-dihydroxyvitamin D3 (Tocris; Cat. #2551), as described previously58 ...
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bioRxiv - Molecular Biology 2024Quote: ... the cells were either plated on laminin-coated 10 cm plates at 1.2×107 cells per plate for continued differentiation or expanded in motor neuron progenitor MNP medium (1× N2B27 medium supplemented with 3 mM CHIR99021, 2 mM DMH1 (Tocris, #4126), 2 mM SB431542 ...
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bioRxiv - Neuroscience 2020Quote: ... Animals were then immobilized by immersion in a solution of 2 mM pancurionium dibromide (Tocris) in 0.1X MBSH for 2-5 min ...
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bioRxiv - Cell Biology 2021Quote: ... and human vasopressin type 2 receptor (V2R) with [Arg8]-vasopressin (AVP; Tocris 2935, in water). The transfected β-arrestins are of bovine origin ...
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bioRxiv - Biochemistry 2022Quote: ... and E3 ligase recruiter building blocks thalidomide - linker 2 (#6468/25) were purchased from Tocris Bioscience (Minneapolis ...
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bioRxiv - Neuroscience 2024Quote: ... VU0360172 [N-cyclobutyl-6-(2-(3-fluorophenyl)ethynyl) pyridine-3-carboxamide] was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... USA) and superfused with ACSF containing 2 mM CaCl2 and 20 µM bicuculline methiodide (Tocris) at a rate of 3 – 4 ml/min at RT ...
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bioRxiv - Neuroscience 2023Quote: ... and exposure to a cocktail of small molecules containing 2 μM each of Dorsomorphin (Tocris), A83-01 (Tocris ...
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The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfallsbioRxiv - Neuroscience 2023Quote: ... a single submaximal concentration (10 µM) of WIN-55,212-2 or HU-210 (Tocris #0966) was used ...
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bioRxiv - Cancer Biology 2023Quote: ... N-(1,3,4-thiadiazol-2-yl) pyridine-3-carboxamide dihydrochloride (TGN-020, Tocris Cat No 5425) was used in vitro at 10-100 μM ...
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bioRxiv - Neuroscience 2023Quote: ... P3029) and 2-methyl-6-(phenylethynyl)pyridine (MPEP; Tocris, Ellisville, MO, Cat. No. 1212/10), solutions were made fresh in sterile saline before use ...
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bioRxiv - Neuroscience 2023Quote: ... organoids were placed in HEPES buffer containing CNQX/APV (2 µM/50 µM, Tocris Bioscience) and imaged immediately.
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bioRxiv - Genomics 2023Quote: ... spent media was replaced with fresh CDM containing 2 µM Wnt-C59 (5148, Tocris Bioscience). CDM was used to replace media on Days 5 ...
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HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesisbioRxiv - Cell Biology 2023Quote: ... the medium was replaced with differentiation medium containing 5 μM IWP-2 (TOCRIS, Cat.# 3533), a Wnt inhibitor ...
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bioRxiv - Immunology 2024Quote: ... 8-to 12-week-old mice were treated with 2 nmol calcipotriol (MC903, Tocris Bioscience) in 10 μL of 100% ethanol (EtOH ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... and (11R)-2-Methyl-11-[(morpholin-4-yl)methyl]-3-(naphthalene-1-carbonyl)-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraene (WIN55,212-2) were acquired from Tocris (Bristol, UK). [(1S,2S,5S)-2-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol (HU308 ...
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bioRxiv - Neuroscience 2024Quote: ... with a dosage of 2 mg/kg of Methoxy-X04 dye (Tocris Bioscience, Bristol, UK). In our setup ...
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bioRxiv - Cell Biology 2021Quote: ... Calcium-like peptide 2 (CALP2) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) were obtained from Tocris (Minneapolis, MN). CaM kinase II and calcineurin inhibitors ...
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bioRxiv - Genomics 2020Quote: ... supplemented with SMAD inhibitors (DMH-1 2 μM Tocris, Cat.: #4423; SB431542-10 μM Tocris, Cat.: #1614 and CHIR99021 3 μM, CHIR Tocris, Cat.: #4423).
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bioRxiv - Neuroscience 2020Quote: ... slices were equilibrated for 10 minutes while being continuously superfused at room temperature with oxygenated aCSF at 1-2 ml/min containing picrotoxin (50 μM, Tocris Bioscience, MO, USA) to block GABAA receptor-mediated inhibitory responses.
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bioRxiv - Neuroscience 2024Quote: ... a third group of animals were treated as those in group 2 with the addition of CB1 receptor antagonist AM251 (1 µM) (Tocris Bioscience, Bristol, UK). After 8 DIV ...
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bioRxiv - Neuroscience 2020Quote: ... JNJ16259685 and 2-Methyl-6-(phenylethynyl)pyridine (MPEP) hydrochloride were purchased from Tocris (Minneapolis MN, USA). (±)-Sulpiride was purchased from MilliporeSigma ...
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bioRxiv - Neuroscience 2020Quote: ... WIN 55,212-2 (WIN, 0.5 µg/0.5-µL infusion/hemisphere; n = 11; Tocris Bioscience, Minneapolis, MN) or VEH (10% DMSO ...
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bioRxiv - Cancer Biology 2022Quote: ... One hour before dsDNA transfection cells were pre-treated with 2 µM NU7441 (#3712, Biotechne/Tocris) in OptiMEM and were subsequently transfected with dsDNA (1 µg/ml) ...
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Microbiology 2020Quote: ... cells were pretreated for 3h before infection with Tautomycetin (0.8 μM, Tocris Bioscience, 119757-73-2) or Okadaic acid (0.1 μM ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2024Quote: Glymphatic inhibition was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience). Mice were treated i.p ...
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bioRxiv - Neuroscience 2024Quote: ... supplemented with 1.25% DMSO and 1.25% Tween 80) or BMS-204352 (2 mg per kg, Tocris) were delivered by intraperitoneal injection 30 min before behavioral testing (as described previously Zhang) ...
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bioRxiv - Neuroscience 2024Quote: ... 2 weeks differentiated BMP4 and CNTF astrocytes were treated with ROCK inhibitor Y27632 (Tocris, 25 μM) or LAT B (Sigma ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... 1-oleoyl lysophosphatidic acid (Tocris), DAMGO (MedChemExpress) ...
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Dopamine depletion can be predicted by the aperiodic component of subthalamic local field potentialsbioRxiv - Neuroscience 2021Quote: ... 4 or 8 μl of 6-OHDA (5 μg in 1 μl saline containing 0.1% ascorbic acid; Tocris, Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA, Tocris Bioscience), Kainate and N-methyl-D-aspartate acid (NMDA ...
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bioRxiv - Cell Biology 2024Quote: The PM fluidity of mammalian cells was measured using 3-((3-((9-(Diethylamino)-5-oxo-5H-benzo[a]phenoxazin-2-yl)oxy)propyl)(dodecyl)(methyl)ammonium)propane-1-sulfonate (NR12S; Tocris Bioscience Cat. No. 7509) using a method as exactly mentioned in Wendy S ...
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bioRxiv - Bioengineering 2024Quote: ... FAST-STEM hiPSCs grown to 80% confluency were dissociated into single cells using TypLE for 5 minutes and seeded into the Aggrewell at a density of 1.2×105 cells per-well in 1 mL of mTesR Plus with 10 μg/mL ROCK Inhibitor Y-27632 (Tocris Bioscience, Bristol, UK; 1254) and 1% Penicillin-Streptomycin (Life Technologies ...
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bioRxiv - Bioengineering 2024Quote: ... was obtained through the administration of exponential doses with concentrations of 1 nM to 10 mM at 2 min intervals before the administration of 10 μM scopolamine (Tocris Bioscience Cat#1414/1G). After another equilibrium period ...
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Rac1, Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneuronsbioRxiv - Neuroscience 2022Quote: Trans ned-19 (Tocris Bioscience), the nicotinic acid adenine dinucleotide phosphate (NAADP ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...