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Citations for Tocris :
401 - 450 of 453 citations for n4 Benzoyl 5 methyldeoxycytidine since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2023Quote: ... (Optopharma Ltd.) and 20 nM for 1-Oleoyl lysophosphatidic acid sodium salt (LPA) (5 mM stock dissolved in water) (Tocris). As controls ...
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bioRxiv - Microbiology 2023Quote: ... cells were resuspended in 25 µl PBS together with 0.25 µl of 5 mM 3-[[(7-Hydroxy-2-oxo-2H-1-benzopyran-3-yl) carbonyl]amino]-D-alanine hydrocholoride (HADA) (Tocris) dissolved in DMSO ...
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bioRxiv - Biophysics 2023Quote: ... The Piezo1 channel activator Yoda1 (5, 10, 20 or 30 μM, dissolved in 10 mM DMSOt, Tocris Bioscience, Bristol, UK) and the Transient Receptor Potential Vanilloid (TRPV4 ...
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bioRxiv - Neuroscience 2024Quote: ... D1-like and D2-like receptors were blocked by applying SFK 83566 hydrobromide for 5 minutes in the bath at 10 µM (1586, Tocris) and sulpiride at 10 µM (S8010 ...
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bioRxiv - Developmental Biology 2024Quote: ... before changing medium on day 3 to RPMI 1640 with 1x B27 minus insulin and 5 mM IWP2 (Tocris 3533). On day 5 ...
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bioRxiv - Bioengineering 2024Quote: ... using a stepwise protocol (Fig. S1a): induction from hESCs to primitive streak by treatment with 5 μM CHIR99021 (#4423, Tocris); induction from primitive streak to paraxial mesoderm by treatments with 5 μM CHIR99021 ...
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bioRxiv - Cell Biology 2024Quote: ... and P2Y1 antagonist 1-(2- (2- tert-butylphenoxy)pyridin-3-yl)-3-(4-(trifluoromethoxy)phenyl)urea (BPTU; BMS- 646786, #870544-59-5) were obtained from Tocris Bioscience (Bristol ...
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bioRxiv - Cell Biology 2024Quote: ... The drugs used were 10 µM para-Nitroblebbistatin (motorPharma, #DR-N-111) or 5 µM Y-27632 (Tocris Bioscience, #1254). As a control we used dimethyl sulfoxide (DMSO ...
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bioRxiv - Developmental Biology 2024Quote: RUES2-GLR hESCs grown routinely in NutriStem® hPSC XF were first plated as single cells at a density of 5.2-6.7 x 103 cells/cm2 with 5 µM Y-27632 (Tocris Biosciences, 1254) for the first 24h after plating ...
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bioRxiv - Neuroscience 2021Quote: ... NMDA receptor (R) dependency was tested by application of an NMDAR antagonist (APV 50 µM, DL-2-Amino-5-phosphonopentanoic acid, Tocris, Germany) in the bath solution ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... and a fourth group (DZP) received 2 mg/kg diazepam (CAS #439-14-5; Tocris, 2805; German-Ponciano et al., 2020) as a pharmacological control of anxiolytic activity ...
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bioRxiv - Physiology 2021Quote: ... Picrotoxin (100 µM) was used to block GABAA-receptor-mediated currents and D-2-amino-5-phosphonovalerate (APV; 20 µMm, Tocris Bioscience), and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Physiology 2021Quote: ... L-364,373 (R-L3 or 5-(2-Fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-2H-1,4-benzodiazepin-2-one) (Tocris Cookson; Bristol, UK) and mefenamic (dimethylphenylaminobenzoic ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: ... supplemented with 100 ng/mL Activin A (R&D, Minneapolis, MN, USA) and 3–5 µM CHIR99021 (Tocris Bioscience, Bristol, UK) (differentiation day 0 ...
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bioRxiv - Neuroscience 2022Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) (both from Tocris, Bristol, UK) to block recurrent glutamatergic signaling.
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bioRxiv - Immunology 2020Quote: ... anti-IgM/CpG-activated or non-activated B cells were incubated with or without reserpine (5 μM, Tocris, catalogue number: 2747), an inhibitor of VMAT-1 & VMAT-2 for 45min ...
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bioRxiv - Developmental Biology 2022Quote: ... are seeded in a 24-well plate (TPP, #92024) at 30-40k cells per well in E8 + ROCKi (5 µM Y-27632, Tocris #1254). All differentiation media are based on CDM that consists of 5 mg/ml bovine serum albumin (Europa Biosciences ...
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bioRxiv - Neuroscience 2023Quote: ... The following compounds were added to raCSF as indicated in the Results section: D-(-)-2-Amino-5-phosphonopentanoic acid (D-APV, 100 μM dissolved in H2O; Tocris Bioscience), (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine maleate (MK-801 ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Neuroscience 2024Quote: ... Both control and CACNA1A+/− networks at DIV49 were treated acutely with 100 µM D-2-amino-5-phosphonovalerate (D-AP5; Tocris, #0106) for 60 min ...
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bioRxiv - Developmental Biology 2023Quote: ... hPSCs were dissociated with EDTA for 10 minutes at 37°C and allowed to aggregate into spheroids of 10,000 cells each in V-bottom 96 well microplates (S-Bio) in E8 medium with ROCK inhibitor (Y-27632, 10 μM) and WNT inhibitor (XAV939, 5 μM, Tocris 3748). The next day (day 0) ...
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bioRxiv - Bioengineering 2023Quote: ... Wnt signaling was inhibited (via the prevention of palmitylation of Wnt proteins by Porcn) from Days 12-19 using the small molecule Wnt-C59 (5 nM; Tocris 5148). After 35 days of differentiation ...
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bioRxiv - Neuroscience 2024Quote: 30 days old mDA neurons were thawed and spun (400 g, 5 min, RT) in a basal medium (Table S2) supplemented with a ROCK inhibitor (Tocris #1254). The cell pellets were then reconstituted in a differentiation medium (Table S2 ...
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bioRxiv - Neuroscience 2024Quote: Cryopreserved 30 days old neurons were thawed in a water bath and centrifuged (400g, 5 min, RT) in basal medium (Table S2) supplemented with ROCK inhibitor (Tocris, #1254). Cell pellets were resuspended in differentiation medium (Table S2 ...
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bioRxiv - Biochemistry 2024Quote: ... pelleted cells were loaded with 2 μM Fura-2/AM and either 1 or 5 μM ci-IP3/PM (Tocris #6210) on 15-mm glass coverslips for an hour at room temperature ...
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bioRxiv - Bioengineering 2024Quote: ... seeded in a 6-well plate at a cell density of 0.3 x 106 cells/well and cultured using mTESRTM Plus medium supplemented with 5 µM Y27632 Rho-kinase (ROCK) inhibitor (Tocris; 1254) for the first 24 hours ...
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bioRxiv - Neuroscience 2020Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) to block glutamatergic signaling (both from Tocris, Bristol, UK). Experiments involving tetrodotoxin (TTX ...
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bioRxiv - Cell Biology 2021Quote: ... Calcium-like peptide 2 (CALP2) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) were obtained from Tocris (Minneapolis, MN). CaM kinase II and calcineurin inhibitors ...
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bioRxiv - Neuroscience 2020Quote: ... VP3.15 was resuspended in 100 mg/mL in DMSO diluted 1:50 in a solution of 5 % Tocrisolve (Tocris®, Minneapolis, USA) to a maximal final volume of 250 µl and the treatment was during 21 days ...
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bioRxiv - Neuroscience 2020Quote: ... 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester (KN-62; Tocris and HelloBio); D-AP5 (HelloBio) ...
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bioRxiv - Neuroscience 2020Quote: ... co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris; 20 μM) (n=13) ...
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bioRxiv - Physiology 2020Quote: ... The MOR antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2, lidocaine, the Ampakine CX614, and the 5-HT4A receptor agonist BIMU8 were obtained from Tocris (ON, Canada).
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... as well as the P2Y2R antagonist AR-C118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide) were obtained from Tocris (Abingdon, UK). Subsequent dilutions of receptor ligand and other reagents were made in Krebs-Ringer Glucose phosphate buffer (KRG ...
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bioRxiv - Neuroscience 2022Quote: ... the medium was replaced with HBSS containing 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate (ARL 67156; Tocris, 1283) at a concentration of 100 μM ...
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bioRxiv - Neuroscience 2022Quote: ... experiments were performed in the presence of GABAA and GABAB blockade (5 µM SR-95531 and 10 µM CGP-52432 respectively; Tocris, Bristol, UK).
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bioRxiv - Neuroscience 2024Quote: ... Cells in dissociation reagent were incubated for 15-20 min at 37οC to ensure dissociation of cell clusters before adding 5 mL of DMEM/F12 containing 0.04% BSA and 10% ROCK inhibitor Y-27632 (1/1000; Tocris; Cat. No. 1254), followed by resuspension by gentle pipetting ...
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bioRxiv - Microbiology 2024Quote: To investigate the impact of gallein (3’,4’,5’,6’-Tetrahydroxyspiro[isobenzofuran-1(3H),9’- (9H)xanthen]-3-one) (Cat#3090, Tocris, Minneapolis, MN) and/or INH on Mtb growth ...
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bioRxiv - Developmental Biology 2022Quote: ... Cells were centrifuged at 400 rpm for 5 mins and resuspended in NBFAK medium supplemented with 10 μM Rho-associated kinase inhibitor Y-27632 (ROCKi, Tocris Bioscience, UK). Cells were counted and seeded at 20 000 cells per well (or as described in the text ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Cell Biology 2023Quote: ... the cells in the AggreWell™ plates were cultured in N2/B27 media that was further supplemented with 5 μM Rock-inhibitor (Tocris 1254), 40 μM SB-431542 (Sigma-Aldrich,S4317) ...
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bioRxiv - Cancer Biology 2024Quote: ... 3 males and 3 females) received a twice daily subcutaneous injection of 100 µL of 5 mg/kg mouse weight of AMG487 (Tocris, Cat# 448710) for 2 weeks ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... The noncompetitive AMPAR antagonist GYKI 52466 [4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride] was purchased from Tocris (R&D Systems, Minneapolis, MN) and dissolved in a vehicle of 0.9% NaCl for intraperitoneal (IP ...
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bioRxiv - Immunology 2024Quote: ... The HCA3R agonists IBC 293 (1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid) and 3-hydroxy-octanoic acid (3-OH-C8) were from Tocris (Bristol, UK) and Cayman Chemical (Michigan ...
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bioRxiv - Developmental Biology 2021Quote: ... dissociation and seeded at a density of 5× 104 cells per cm2 in mTeSR1 supplemented with 10μM Y-27362 dihydrochloride (Rocki; Tocris Bioscience, cat. no. 1254).
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bioRxiv - Molecular Biology 2020Quote: iAT2s plated in ALI culture were pre-treated apically (100 μL) and basolaterally (600 μL) with the indicated concentrations of camostat mesylate (Tocris, #59721-29-5), E-64d (Selleckchem ...
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bioRxiv - Cell Biology 2021Quote: iPSC-airway plated in ALI culture were pre-treated apically (100 μL) and basolaterally (600 μL) with the indicated concentrations of camostat mesylate (Tocris, #59721-29-5), remdesivir (Selleckchem ...
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bioRxiv - Neuroscience 2023Quote: ... A set of 4 proconvulsive compounds were chosen to induce seizurogenic responses of the neuronal network at DIV 49: NMDA (100 μM working concentration, Tocris, #6384-92-5), Linopirdine (1.5 μM ...
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bioRxiv - Neuroscience 2024Quote: ... Digested brain solution was transferred into a glass dounce homogenizer on ice with 5 mL ice-cold flow cytometry (FACS) buffer comprising 2.5% bovine serum albumin (BSA; Tocris Bioscience Cat. 5217/100G) and 1 M ethylenediaminetetraacetic acid (EDTA ...
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bioRxiv - Neuroscience 2020Quote: ... The bath solution for recordings contained elevated concentrations of divalent cations [4 mM Ca2+ and 4 mM Mg2+] and NMDA receptor antagonist 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) [5 mM] (Tocris biosciences, 126453-07-4). Slices were used 1.5–4.5 hours after preparation ...
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bioRxiv - Cell Biology 2024Quote: The PM fluidity of mammalian cells was measured using 3-((3-((9-(Diethylamino)-5-oxo-5H-benzo[a]phenoxazin-2-yl)oxy)propyl)(dodecyl)(methyl)ammonium)propane-1-sulfonate (NR12S; Tocris Bioscience Cat. No. 7509) using a method as exactly mentioned in Wendy S ...