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Citations for Tocris :
401 - 450 of 1232 citations for 5 2 3 Difluorophenyl 5 oxovaleric acid since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2020Quote: ... the GABAA receptor antagonist gabazine (SR 95531 hydrobromide, Tocris, Wiesbaden-Nordenstadt, Germany, 5 μM) was bath-applied for 60 min after having recorded a minimum of 20 min stable baseline responses ...
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bioRxiv - Neuroscience 2020Quote: ... mEPSCs were recorded for 5 min in the presence of 1 μM tetrodotoxin (Tocris), 10 μM CPP (Tocris) ...
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bioRxiv - Cell Biology 2022Quote: At day 0 cells were treated with 5 nM 4-Hydroxytamoxifen (+HOT) (Tocris, 3412) or with vehicle (-HOT ...
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bioRxiv - Developmental Biology 2021Quote: ... medium was replaced with BPEL containing 5 μmol/L XAV939 (Tocris Bioscience, #3748/10). For SANCM differentiation ...
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bioRxiv - Neuroscience 2021Quote: ... saline or CNO (5 mg/kg, Clozapine N-oxide dihydrochloride, Tocris, Cat. No. 6329) was injected intraperitoneally (i.p. ...
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bioRxiv - Neuroscience 2023Quote: ... (-)-quinpirole HCl (QUIN; 0.05 mg/kg, 1 mg/kg or 5 mg/kg; Tocris), raclopride HCl (RACLO ...
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bioRxiv - Physiology 2023Quote: ... saturated with 95% O2 and 5% CO2 with the ectonuclease inhibitor ARL67156 (100 μM) (Tocris) for 20 min ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were treated for 24 hours with 5 uM araC (Tocris 45-205-0) and media was replaced on day 3 with fresh Neuron Differentiation Media without ROCK inhibitor or araC ...
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bioRxiv - Developmental Biology 2023Quote: ... culture medium was changed to MCDB131 base medium supplemented with 5 μM CHIR99021 (Tocris) and 100 ng/ml Activin A (R&D System ...
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bioRxiv - Cell Biology 2024Quote: ... Trp53 loss was selected by supplementing media with 5 μM Nutlin-3a (Tocris, 6075). Rb1 loss was selected for by supplementing media with 2.5 μM Palbociclib (Tocris ...
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bioRxiv - Cancer Biology 2022Quote: ... the small molecule 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one (iMDK; TOCRIS Bio-techne, 9mg/kg), rapamycin (Sirolimus A8167 ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Neuroscience 2024Quote: Glymphatic inhibition was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience). Mice were treated i.p ...
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bioRxiv - Neuroscience 2020Quote: ... the N3 media was further supplemented with two factors: SB-431542 (5 µM, Tocris, 1614) and LDN-193189 (100 nM ...
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bioRxiv - Immunology 2022Quote: ... or an inhibitor of CD73 inhibitor (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) (0.5 mg/mouse ...
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bioRxiv - Neuroscience 2021Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247 ...
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bioRxiv - Cell Biology 2021Quote: ... SB431542 (#1614) and guanosine 5′-[β,γ-imido]triphosphate (GMPPNP, #G0635) were purchased from Tocris and Sigma-Aldrich ...
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bioRxiv - Neuroscience 2022Quote: ... for 5 min at 37°C and replating in 10μM ROCK inhibitor Y-27632 (Tocris) for 24h.
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bioRxiv - Neuroscience 2020Quote: Zebrafish larvae (5–6 dpf) were first paralysed in 1 mM α-Bungarotoxin solution (Tocris) for 3–6 min after which they were pinned in a lateral position to a Sylgard-coated recording dish (Sylgard 184 ...
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bioRxiv - Neuroscience 2021Quote: ... Cdk-5 inhibitor (Roscovitine, 10 µM) and GSK-3β inhibitor CHIR 98014 (10 µM, Tocris) were added 30 min prior to IL-13 treatment ...
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bioRxiv - Neuroscience 2022Quote: ... 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate (ARL 67156; Tocris, 1283) was perfused through the probe at concentrations of 1 mM ...
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bioRxiv - Neuroscience 2022Quote: ... The two agents used were a mixture of AMPA (5 mM) (Cat no. 0254, Tocris) and NMDA (10 mM ...
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bioRxiv - Neuroscience 2023Quote: ... we applied for 5 minutes the specific sodium channel blocker tetrodotoxin (TTX, 500 nM, Tocris) in combination with potassium channel blocker 4-aminopyridine (4-AP ...
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bioRxiv - Bioengineering 2023Quote: ... or pharmacological inhibitors of focal adhesion kinase (FAK) (FAK inhibitor 14, 5 µM, Tocris, UK), Rho-associated protein kinase (ROCK ...
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bioRxiv - Systems Biology 2023Quote: ... Cells were assayed by flow cytometry after 5 days of 1 µg/mL doxycycline (Tocris) treatment for repressors and 2 days of doxycycline for activators ...
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bioRxiv - Cell Biology 2024Quote: ... then blocked in Tween 0.1% Tris-buffered saline containing 5% bovine serum albumin (Tocris 5217) for at least 1h at room temperature and subsequently incubated overnight at 4°C with primary antibodies ...
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bioRxiv - Neuroscience 2021Quote: ... quisqualic acid (QA – Tocris), and N-methyl-D-aspartic acid (NMDA ...
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bioRxiv - Neuroscience 2021Quote: ... kainic acid (Tocris 0222), Ph-KA (made in-house) ...
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bioRxiv - Neuroscience 2020Quote: ... flufenamic acid (4522, Tocris), nifedipine (1075 ...
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bioRxiv - Neuroscience 2024Quote: ... Valproic acid (0.5mM, Tocris) was added on day 13 ...
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bioRxiv - Molecular Biology 2024Quote: ... kainic acid (Tocris; 0222) was dissolved in 0.9% sodium chloride solution (Henry Schein ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...
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bioRxiv - Synthetic Biology 2022Quote: (5Z)-5[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4H-imidazol-4-one (DFHBI-1T) was purchased from Tocris Bio-techne ...
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bioRxiv - Immunology 2022Quote: ... or a CD73 inhibitor (0–1 μM) (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) plus ATP (100 μM ...
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bioRxiv - Neuroscience 2020Quote: ... Membranes were blocked for 1 hour at RT on a shaker in 5% BSA (Tocris, 5217) with 0.1% Tween-20 (Bio-Rad ...
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bioRxiv - Neuroscience 2020Quote: ... and N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide (IEM-1460, Tocris) were prepared as 10 mM stocks dissolved in distilled water ...
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bioRxiv - Neuroscience 2023Quote: ... 5-HT1A-R agonist 8-OH-DPAT or antagonist NAN-190 (NAN) were from Tocris (UK). Competition was performed at concentration between 10−11 to 10−5 M ...
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bioRxiv - Neuroscience 2023Quote: ... The following peptides were delivered in 5 µL of sterile saline: GRP (295 ng, Tocris 1789), Substance P (400 ng ...
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Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutationbioRxiv - Pathology 2023Quote: ... cells were treated with RPMI enriched with insulin-free B27 and 5 µM IWP2 (Tocris Bioscience) for 48 hours and then the medium was replaced with RPMI enriched with insulin-free B27 ...
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bioRxiv - Neuroscience 2024Quote: ... All experiments were performed in the presence of SR95531 (5 mM, Tocris Bio-Techne, Minneapolis, MN) and CGP55845 (2.5 mM Tocris ...
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Developmental Biology 2021Quote: ... paraxial mesoderm (1 day; 20 ng/ml FGF2, 3 µM CHIR99021, 2 µM SB505124 [cat. num. 3263; Tocris Bioscience ...
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bioRxiv - Neuroscience 2021Quote: ... the group 2/3 mGluR agonist (DCG-IV) and MNI-glutamate for uncaging experiments were purchased from Tocris Bioscience ...
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bioRxiv - Cell Biology 2023Quote: ... Neurosensor 510 (7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde) was purchased from (Tocris).
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Promoting Human Intestinal Organoid Formation and Stimulation Using Piezoelectric Nanofiber MatricesbioRxiv - Bioengineering 2024Quote: ... 2% dFCS,) for four days with 100 ng/ml FGF4 (R&D) and 3 µM Chiron 99021 (Tocris) to induce the formation of spheroids ...
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bioRxiv - Neuroscience 2022Quote: ... Kainic acid (KA) (Tocris, USA) was dissolved in saline to provide a solution with a concentration of 20 mM ...