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401 - 450 of 655 citations for 4 4 7 Triethoxy 7 Methyl 3 8 Dioxa 4 7 Disiladecane since 2020

• Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

  Young Sun Hwang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience) and 10 μM of a ROCK inhibitor ...
• Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis

  Chloé Berland, et al., bioRxiv - Neuroscience 2021

  Quote: ... AM251 (3 mg/kg, Tocris), AM6545 (10 mg/kg ...
• A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

  Kunimichi Suzuki, et al., bioRxiv - Neuroscience 2020

  Quote: ... CGP 55845 (3 μM, Tocris), and tetrodotoxin (Tocris ...
• Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context

  Luigi Russo, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 3 μM CHIR99021 (Tocris) or 50 ng/ml Activin A (Peprotech) ...
• Kinetochores respond to subtle changes in the stability of microtubule attachments

  Jessica D. Warren, et al., bioRxiv - Cell Biology 2021

  Quote: ... ZM447439 (3 μM; Tocris Bioscience), Okadaic Acid (100 nM ...
• C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein

  Yuma Kato, et al., bioRxiv - Neuroscience 2021

  Quote: ... 3 μM SB431542 (Tocris, UK), and 3 μM CHIR99021 (Focus Biomolecules ...
• Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord

  Kalaimakan Hervé Arulkandarajah, et al., bioRxiv - Neuroscience 2020

  Quote: ... gabazine (3 μM, Tocris, USA), CNQX Disodium (20 μM ...
• LTD at amygdalocortical synapses as a novel mechanism for hedonic learning

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Altered Thalamocortical Signaling in a Mouse Model of Parkinson’s Disease

  Olivia K. Swanson, David Richard, Arianna Maffei, bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Erev[Cl−] = −49.8mV)) ...
• CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cells development

  Young Sun Hwang, M. Andrés Blanco, Kotaro Sasaki, bioRxiv - Developmental Biology 2022

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience) and 10 μM of a ROCK inhibitor ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 3 μM CHIR99021 (Tocris)) was added to each lower chamber ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... IPA-3 (1 μM; Tocris), BDP-9066 (1 μM ...
• Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons

  Yoshifumi Sonobe, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 3 µM CHIR99021 (Tocris Bioscience), 2 µM DMH1 (Tocris Bioscience) ...
• Design, implementation, and functional validation of a new generation of microneedle 3D high-density CMOS multi-electrode array for brain tissue and spheroids

  Lisa Mapelli, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 μM TTX (tetrodotoxin, Tocris) was added to the Krebs solution ...
• An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• Inhibitory gating of thalamocortical inputs onto rat gustatory insular cortex

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... CHIR99021 3 μM (4423, Tocris), holo-transferrin 10 μg/ml (T0665 Sigma) ...
• Electron microscopic analysis of the influence of iPSC-derived motor neurons on bioengineered human skeletal muscle tissues

  Christine T. Nguyen, et al., bioRxiv - Cell Biology 2023

  Quote: ... 3 μM CHIR99021 (Tocris 4423) and 200 μM ascorbic acid (Sigma-Aldrich ...
• Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation

  Sina Schumacher, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 µM CHIR99021 (Tocris), referred to as 2i + LIF.33 N2B27 was prepared as a 1:1 mixture of DMEM/F12 and Neuropan Basal Medium (both from PAN Biotech) ...
• Ca²⁺-sensing receptor regulates neuronal excitability via Kv7 channel and G_i/o protein signalling

  Nontawat Chuinsiri, et al., bioRxiv - Physiology 2023

  Quote: ... 3 μM CHIR-99021 (Tocris), 200 μM L-ascorbic acid (Merck) ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris). In base control strategy #14 ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• Modulation of sweet preference by neurosteroid-sensitive, δ-GABA_A receptors in adult mouse gustatory insular cortex

  Priscilla E Yevoo, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (reversal potential (Vrev)[Cations] = 10mV) ...
• cAMP−EPAC−PKCε−RIM1α signaling regulates presynaptic long-term potentiation and motor learning

  Xin-Tai Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... 8-pCPT (4853) and FR236924 (3091) were from Tocris (Bristol, UK). Dulbecco’s modified Eagle’s medium (DMEM ...
• CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency and cell death

  Paul Chammas, et al., bioRxiv - Developmental Biology 2024

  Quote: ... culture media was changed and 8 µg/mL polybrene (7711, Tocris) was added to the media prior to the addition of 15 µl of concentrated virus ...
• A “double-edged” role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs

  Serena Notartomaso, et al., bioRxiv - Neuroscience 2024

  Quote: ... VU0360172 [N-cyclobutyl-6-(2-(3-fluorophenyl)ethynyl) pyridine-3-carboxamide] was purchased from Tocris Bioscience (Bristol ...
• The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function

  Subhrajit Banerjee, et al., bioRxiv - Cell Biology 2024

  Quote: The PM fluidity of mammalian cells was measured using 3-((3-((9-(Diethylamino)-5-oxo-5H-benzo[a]phenoxazin-2-yl)oxy)propyl)(dodecyl)(methyl)ammonium)propane-1-sulfonate (NR12S; Tocris Bioscience Cat. No. 7509) using a method as exactly mentioned in Wendy S ...
• Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells

  Jose Ernesto Canton-Josh, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 μM Pyr-3 (Tocris,3753), 1 mM MNI-caged-L-glutamate ...
• Single-cell profiling of transcriptome and histone modifications with EpiDamID

  Franka J. Rang, et al., bioRxiv - Genomics 2021

  Quote: ... 3 μM CHIR99021 (Tocris, SML1046-5MG), 1000 U/mL ESGRO mLIF ...
• Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

  Kizito-Tshitoko Tshilenge, et al., bioRxiv - Neuroscience 2022

  Quote: ... GABA (3 mM, Tocris Bioscience, 0344), CaCl2 (1.8 mM ...
• Identification of the main barriers to Ku accumulation in chromatin

  Madeleine Bossaert, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or NU-7441 (3 µM, Tocris) were added when specified 1 h prior to irradiation ...
• Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A

  Robert Prior, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 mM CHIR-99021 (Tocris Biosciences), and 20 µM SB 431542 (Tocris Biosciences) ...
• 3D genome organization around nuclear speckles drives mRNA splicing efficiency

  Prashant Bhat, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 3 μM CHIR 99021 (Tocris, 4423), and 50 nM PI 103 (Tocris ...
• Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis

  Taisei Wakigawa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... IPA-3 (Tocris, 3622, 5 μM), CK666 (Tocris ...
• Recording morphogen signals reveals origins of gastruloid symmetry breaking

  Harold M. McNamara, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CHIR99021 3 μM (4423, Tocris). After 3 days ...
• Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways

  Evan J. Underhill, Jared E. Toettcher, bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).
• Elevated ENO2 Disrupts VSMCs Homeostasis Facilitating the Development of Aortic Dissection

  Weixing Cai, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ang II (4474-91-3, Tocris) was injected subcutaneously at a total dose of 1 ...
• Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway

  Artemis Koumoundourou, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 μM DCG-IV (Tocris Bioscience) was applied after each experiment ...
• Human neuron subtype programming through combinatorial patterning with scRNA-seq readouts

  Hsiu-Chuan Lin, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 3 µM CHIR99021 (Tocris Bioscience).
• Engineering fluorescent reporters in human pluripotent cells and strategies for live imaging human neurogenesis

  Alwyn Dady, et al., bioRxiv - Developmental Biology 2024

  Quote: ... supplemented with 3 µM Chiron99021 (Tocris) and 20 ng/ml bFGF (PeproTech ...
• GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory

  Hyun Jin Kim, et al., bioRxiv - Neuroscience 2024

  Quote: ... Ifenprodil hemitartrate (3 μM, #0545, Tocris) and PPDA (0.1 μM ...
• Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons

  Madison R. Glass, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience # 4423) and the MEK inhibitor ...
• Modelling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype

  Stephen Qi Rong Wong, et al., bioRxiv - Cancer Biology 2024

  Quote: Oxaliplatin (CAS#: 61825-94-3, Tocris) was dissolved in DMSO ...
• The transcription factor GABPA is a master regulator of naïve pluripotency

  Chengjie Zhou, Meng Wang, Chunxia Zhang, Yi Zhang, bioRxiv - Developmental Biology 2024

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).
• Identification of Thioredoxin1 interacting proteins in neuronal cytoskeletal organization during autophagy

  Md Imamul Islam, et al., bioRxiv - Biochemistry 2024

  Quote: ... HT22 cells were then treated with 8 µg/ml of puromycin (TOCRIS, 4089) in FBS/DMEM media ...
• Extracellular glutamate and GABA transients at the transition from interictal spiking to seizures

  Yoshiteru Shimoda, et al., bioRxiv - Neuroscience 2023

  Quote: Picrotoxin and pilocarpine hydrochloride were purchased from Tocris (CAS number: 124-87-8) and Sigma-Aldrich (CAS number ...
• Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization

  Marine Berquez, et al., bioRxiv - Cell Biology 2023

  Quote: ... ATP-competitive mTOR inhibitor Torin1 (TOCRIS Bioscience, CAS 1222998-36-8, 250 nM), allosteric mTOR inhibitor rapamycin (Sigma Aldrich ...
• Chrna5 is essential for a rapid and protected response to optogenetic release of endogenous acetylcholine in prefrontal cortex

  Sridevi Venkatesan, Evelyn K. Lambe, bioRxiv - Neuroscience 2020

  Quote: ... Dihydro-β-erythroidine (DhβE, 3 μM, Tocris) was used to block β2 containing nicotinic receptors ...
• The mammalian rod synaptic ribbon is essential for Ca_v channel facilitation and ultrafast fusion of the readily releasable pool of vesicles

  Chad Paul Grabner, Tobias Moser, bioRxiv - Biophysics 2020

  Quote: ... at a concentration of 3 μM (TOCRIS). It showed better stability over time ...