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Citations for Tocris :
401 - 450 of 501 citations for 2 Trimethylsilyl ethynyl toluene since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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Pathogenic CD8 T cell responses are driven by neutrophil-mediated hypoxia in cutaneous leishmaniasisbioRxiv - Immunology 2023Quote: ... the sections were counter-stained with the nuclear probe 4’,6-diamino-2-phenylindole (DAPI, Biotechne-Tocris, UK). Slides were covered with Prolong™ Gold Antifade Mountant (Invitrogen ...
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bioRxiv - Biophysics 2023Quote: ... whereas IS-2 sample was made up to 100 µM CTZ and 100 µM GYKI- 52466 (Tocris, 1454) prior to centrifugation (75,000 g ...
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Promoting Human Intestinal Organoid Formation and Stimulation Using Piezoelectric Nanofiber MatricesbioRxiv - Bioengineering 2024Quote: ... 2% dFCS,) for four days with 100 ng/ml FGF4 (R&D) and 3 µM Chiron 99021 (Tocris) to induce the formation of spheroids ...
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bioRxiv - Cell Biology 2020Quote: ... Cyclopiazonic-acid (CPA) and 2’(3’)-O-(4-Benzoylbenzoyl)adenosine-5’-triphosphate (BzATP) triethylammonium salt was purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2021Quote: ... d-2-Amino-5-phosphonovaleric acid (d-AP5, 50µM) and the sodium (Na+) channel blocker tetrodotoxin (TTX, 1 µM Tocris). Individual traces (5 sec duration ...
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bioRxiv - Neuroscience 2021Quote: ... and nor-Binaltorphimine dihydrochloride (norBNI, KOR antagonist, 10 mg/kg, i.p.) (CAS# 113158-34-2) were obtained from Tocris and dissolved in 0.9% sterile saline ...
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bioRxiv - Biochemistry 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy] butanoic acid (DCPIB) was purchased from Tocris Bioscience and reconstituted to 50 mM in DMSO ...
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bioRxiv - Neuroscience 2020Quote: ... 20 μM 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 20 μM D-(-)-2-amino-5-phosphopentanoic acid (D-AP5) (Tocris Bioscience) to block glycine- ...
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bioRxiv - Neuroscience 2020Quote: ... CGP 55845 ((2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl] (phenylmethyl) phosphinic acid hydrochloride) and GRK2i were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Cell Biology 2022Quote: To observe chromosome alignment in fixed-cell experiments – with the advantage of taking high resolution images and easily selecting many cells for further analysis - cells were released from thymidine block for 7 hours before being treated for 2 hours with RO-3306 (10μM, Tocris) – to synchronise cells at the G2/M boundary - or with a 3-hour treatment with STLC (10μM ...
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bioRxiv - Biophysics 2022Quote: ... 100 μM 2-APB blocking stretch-activated inositol triphosphate receptors (InsP3Rs) on the ER/nuclear membranes (Tocris Bioscience #1224), 100 μM CK-666 (Tocris Bioscience #3950 ...
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bioRxiv - Neuroscience 2020Quote: ... were performed on mice with no knee injections 20 min before and after C21 (2 mg/kg diluted in sterile saline from a stock of 100 mM in ethanol, i.p., Tocris) injection.
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bioRxiv - Physiology 2021Quote: ... resiniferatoxin and 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide (BCTC) were purchased from Tocris Bioscience or Adooq Bioscience and stock solutions were prepared in EtOH at 1 M and 100 mM ...
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bioRxiv - Neuroscience 2021Quote: ... The mGluR5 specific negative allosteric modulator MPEP hydrochloride (2-Methyl-6-(phenylethynyl)pyridine hydrochloride) was purchased from Tocris (1212) and administered to brain slices at 30 μM by bath perfusion ...
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bioRxiv - Neuroscience 2021Quote: ... 4-(4-,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl) benzeneacetamide (GW627368X 3 µM, Tocris); 6-Isopropoxy-9-xanthone-2-carboxylic acid (AH6809 ...
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bioRxiv - Cell Biology 2021Quote: ... AKT (20 μM MK2206, Cayman Biochemicals #1032350-13-2) and myosin ATPase activity inhibitor (5 μM Blebbistatin, Tocris #1852).
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bioRxiv - Immunology 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid (DCPIB, 1540) was from Tocris. NS3728 and NBC19 were made at the University of Manchester.
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bioRxiv - Cell Biology 2021Quote: ... organoids cultured for 8 days with airway cell culture medium were followed by inclusion of CHIR99021 (2 µM, Tocris) for additional 10 days with or without DAPT (20 µM) ...
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bioRxiv - Neuroscience 2020Quote: ... all electrophysiological recordings were performed in the presence of picrotoxin (100μM) and 3-((R)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP; 10μM; Tocris Bioscience), and a cut was made between CA3 and CA1 regions to prevent the propagation of epileptiform activity ...
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bioRxiv - Neuroscience 2023Quote: Pharmacological inhibition of AQP4 was achieved using TGN-020 (N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide, Tocris Bioscience, UK). Unless otherwise stated ...
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bioRxiv - Cell Biology 2023Quote: ... 3- (4,5-dimmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays were used to estimate cell number following the manufacturer’s description (Tocris, # 5224), and absorbance was measured at 550 nm in an EnsightTM 96-well plate reader (Perkin Elmer).
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bioRxiv - Molecular Biology 2023Quote: ... BI stands for Broccoli aptamer ligand (5Z)-3-(1H-Benzimidazol-7-ylmethyl)-5-[(3,5-di-fluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-4H-imidazol-4-one dihydrochloride) (Cat. No. 7466, Tocris) (14) ...
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Self-organised pattern formation in the developing neural tube by a temporal relay of BMP signallingbioRxiv - Developmental Biology 2023Quote: ... cells were dissociated from the 100 mm dishes and 2.8-3M cells per well were seeded on the prepared 2-well dishes in N2B27 medium with 10ng/ml bFGF + 10µM Y-27632 ROCK inhibitor (Tocris) media for 3h ...
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bioRxiv - Neuroscience 2024Quote: ... Eye movements were further prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Cell Biology 2024Quote: ... supplemented with 5.5 mM glucose prior to sequential 30 min incubations of KRBH containing low (2 mM) and high (20 mM) glucose with or without 2.5 nM GIP (Tocris Bioscience ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... adrenergic agonist Xylazine Chloride (XYL, 2% m.V-1, Anasedan®) and opioid agonist Ala2-MePhe4-Gliol5-encephalin (DAMGO, Tocris) and their specified doses were diluted to a final injection volume of 20µL either in sterile NaCl 0,9% m.V-1 (saline ...
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bioRxiv - Neuroscience 2024Quote: ... and 5 μM (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP, NMDA receptor antagonist, Tocris, 0173) were added to the aCSF and perfused for 3 min after which the synaptic responses of the neurons to photostimulation were measured again ...
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bioRxiv - Neuroscience 2024Quote: Recordings were performed at ∼34°C in ACSF (flow rate 2–4 ml / min) containing inhibitory receptor blockers picrotoxin (20µM; Tocris), CGP 55845 (1µM ...
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bioRxiv - Biochemistry 2024Quote: ... with or without the gamma-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester (DAPT; Tocris, 2634) at a final concentration of 10 µM ...
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bioRxiv - Immunology 2024Quote: ... The FFA2R antagonist CATPB ((S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl) phenyl) butanoic acid) was from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2021Quote: ... Four of the rats were also infused with 2 μL of either physiological saline or 5 μg/μL yohimbine (Tocris) with a flow rate of 0.5 μL/min as previously reported (Caetano et al. ...
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bioRxiv - Genomics 2020Quote: ... The involvement of the TLR1/2 in signal transduction was tested using CU-CPT22 at 10 µM (Tocris Bioscience, UK). The used concentrations of inhibitors were selected based on recommendations provided by the manufacturers ...
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bioRxiv - Neuroscience 2020Quote: ... and the Mai Tai eHP was tuned to 725nm for photoactivation of recirculated caged MNI-L-glutamate (2 mM, Tocris)57,58 ...
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bioRxiv - Neuroscience 2020Quote: ... or by either bath application or using a custom-made perfusion system (for imaging cells on 12-mm coverslips): 2-AG (Tocris), AEA (Cayman) ...
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bioRxiv - Neuroscience 2021Quote: ... mEPSCs were recorded in aCSF supplemented with 10 μM N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-2-naphthalen-1-ylacetamide trihydrochloride (NASPM, Tocris) to selectively block CP-AMPARs ...
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bioRxiv - Neuroscience 2020Quote: ... QX-314 (Cat No. 1014); and D-2-amino-5-phosphonovalerate (D-AP5; Cat No. 0106) were purchased from Tocris.
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bioRxiv - Neuroscience 2021Quote: Potassium currents were isolated pharmacologically during whole-cell voltage-clamp recordings by blocking fast sodium and calcium channels as well as ionotropic receptors for GABA and glutamate (2 µM tetrodotoxin (TTX, Tocris), 300 µM NiCl2 ...
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bioRxiv - Neuroscience 2020Quote: ... The GAT1 blocker NO-711 [(1,2,5,6-tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride] and GAT3 blocker SNAP-5114 [1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid] were purchased from Tocris Bioscience (Minneapolis ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Cancer Biology 2022Quote: ... and 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazoledihydro-chloride (MPP; cat# 1991) were purchased from Tocris Bioscience ...
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A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down ScalingbioRxiv - Neuroscience 2021Quote: ... 6 hrs (Figure 6 – figure supplement 2) or 24 hrs after transfection (the remaining experiments) neurons were treated with tetrodotoxin (TTX, 5 µM, Tocris) for ∼16 hours ...
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bioRxiv - Cell Biology 2021Quote: ... and seeded at a seeding density of 10000-25000 cells/cm2 in mTeSR supplemented with 2 µM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Cancer Biology 2021Quote: ... and single-cell suspensions were re-plated in mTeSR1 supplemented with 2 µM ROCK inhibitor (Y-27632 Dihydrochloride Tocris #1254). Transgenic WT29 iPSCs were generated by transfecting PiggyBac expression vector and pBase (Villegas et al ...
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bioRxiv - Neuroscience 2020Quote: The FPR2 agonist Compound-43 (N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...
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bioRxiv - Microbiology 2022Quote: ... 3 μl of 10 mM of NBD-(linezolid-7-nitrobenz-2-oxa-1,3-diazol-4-yl)-amino-D-alanine (NADA) (Tocris Bioscience) was added to the resuspension ...
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bioRxiv - Cell Biology 2022Quote: Compounds which were considered a hit after library screening were purchased from the following commercial suppliers: 2-TEDC (Tocris Bioscience), Anethole-trithione (ATT ...
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bioRxiv - Pathology 2022Quote: About 0.1 to 0.2 MOI (Multiplicity of Infection) equivalent of VSV-G and pseudotype SARS-CoV-2 spike virus particles were treated with recombinant LL37 (Tocris) and niacinamide (vitamin B3 ...
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bioRxiv - Cell Biology 2022Quote: ... resuspended in DMEM-1%BSA and incubated in suspension for 30 min at 37°C in 10% CO2 and 2 μg/ml CT04 (#CT04-A, Cytoskeleton or 10 μM EHT1864 (#3872, Tocris). The vehicle control included the corresponding dilution of DMSO as needed ...
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bioRxiv - Microbiology 2024Quote: ... the cells were hybridized with V-EV71-C1 probe (Biotechne) at 40°C for 2 hours and then the signals were revealed using TSA Vivid 570 kit (Tocris). The slides were then incubated with blocking buffer and incubated with MAB979 (1:100 ...