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4201 - 4250 of 7257 citations since 2019

• Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels

  Marc Duque, et al., bioRxiv - Neuroscience 2021

  Quote: ... directly dissolved in culture media and TTX76 (18μM; tetrodotoxin citrate; Tocris #1069 ...
• Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels

  Marc Duque, et al., bioRxiv - Neuroscience 2021

  Quote: ... A78416874 (20μM; Tocris, #4319, 45 min incubation) in 0.1% DMSO ...
• Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels

  Marc Duque, et al., bioRxiv - Neuroscience 2021

  Quote: ... we used yoda-172 (10μM in DMSO; Tocris #5586). For activation of TRPV1 we used capsaicin73 (3μM in DMSO ...
• Sonogenetic control of mammalian cells using exogenous Transient Receptor Potential A1 channels

  Marc Duque, et al., bioRxiv - Neuroscience 2021

  Quote: ... nocodazole (5μM; Tocris, #1228), jasplakinolide (200μM ...
• HIF-dependent Neuropeptide Y Receptor Y1 and Y5 expression sensitizes hypoxic cells to NPY stimulation

  Philip J. Medeiros, et al., bioRxiv - Molecular Biology 2021

  Quote: ... was given to cells 1 h prior to treatment with NPYR agonists (Tocris; 10 nM): NPY (cat#1153) ...
• Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor

  Youwen Zhuang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... The LY3154207 compound was added into the cell suspension at the concentration of 10μM after the first half-hour incubation with 10μM SKF81297 (Tocris) and together with the addition of apyrase (25 mU mL−1 ...
• Piezo1 and BK_Ca channels in human atrial fibroblasts: interplay and remodelling in atrial fibrillation

  Dorothee Jakob, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and iberiotoxin (100 nmol/L, Tocris, Bristol, UK) were used ...
• Mutation-specific reporter for the optimization and enrichment of prime editing

  I.F. Schene, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and 10 mM FSK (Tocris). Small intestine and colon organoids were plated in matrigel and maintained in SI-EM ...
• Mutation-specific reporter for the optimization and enrichment of prime editing

  I.F. Schene, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 5 mM A83-01 (Tocris), and 10 mM FSK (Tocris) ...
• “Prefrontal cortical contributions to working memory loading, maintenance and recall are parsed by hippocampal-prefrontal oscillatory assembly dynamics”

  Aleksander P.F. Domanski, et al., bioRxiv - Neuroscience 2021

  Quote: CP55940 (Tocris) was diluted in a vehicle solution (10% ethanol ...
• Varenicline Prevents SARS-CoV-2 Infection In Vitro and in Rhesus Macaques

  Jeffrey Nau, et al., bioRxiv - Immunology 2021

  Quote: ... Varenicline tartrate was purchased from Tocris Biosciences (Minneapolis ...
• Excess dietary sugar impairs colonic epithelial regeneration in response to damage

  Ansen H.P. Burr, et al., bioRxiv - Immunology 2021

  Quote: ... 10μM Y-27632 (Tocris 1254), 10nM Gastrin I (Sigma Aldrich G9020) ...
• Structural insights into human excitatory amino acid transporter EAAT2

  Takafumi Kato, et al., bioRxiv - Molecular Biology 2021

  Quote: ... the uptake of 10 μM of 14C-Glutamate was measured with or without the indicated concentrations of WAY213613 (Tocris, Bio-Techne, US). Expression of EAAT2 in total membranes was analyzed by immunoblotting ...
• RBBP6 activates the pre-mRNA 3’-end processing machinery in humans

  Vytaute Boreikaite, et al., bioRxiv - Molecular Biology 2021

  Quote: The prodrug of JTE-607 was purchased from Tocris and hydrolyzed to JTE-607 acid analog as previously described (Ross et al. ...
• Modelling human zygotic genome activation in 8C-like cells in vitro

  Jasmin Taubenschmid-Stowers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 2μM XAV939 (Tocris Bio-Techne, 3748) and 10ng/ mL human LIF (WT-MRC Cambridge Stem Cell Institute ...
• Modelling human zygotic genome activation in 8C-like cells in vitro

  Jasmin Taubenschmid-Stowers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 2μM Gö6983 (Tocris Bio-Techne, 2285), 1μM CHIR99021 (WT-MRC Cambridge Stem Cell Institute ...
• Modelling human zygotic genome activation in 8C-like cells in vitro

  Jasmin Taubenschmid-Stowers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 2μM Gö6983 (Tocris Bio-Techne, 2285), 2μM XAV939 (Tocris Bio-Techne ...
• High-throughput identification of RNA localization elements reveals a regulatory role for A/G rich sequences

  Ankita Arora, et al., bioRxiv - Molecular Biology 2021

  Quote: ... at 3,000 cells per cluster in the presence of 10 uM Rock Inhibitor Y-27632 (RI, Tocris #1254). 24 hours later ...
• Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment

  Le Thi My Le, et al., bioRxiv - Biochemistry 2021

  Quote: ... either 5 mM ATPγS (TOCRIS) or 5 mM orthovanadate and 10 mM MgCl2 ...
• Differential regulation of prelimbic and thalamic transmission to the basolateral amygdala by acetylcholine receptors

  Sarah C. Tryon, et al., bioRxiv - Neuroscience 2021

  Quote: ... and VU10010 were purchased from Tocris Biosciences (Bristol ...
• Single-molecule, full-length transcript isoform sequencing reveals disease mutation-associated RNA isoforms in cardiomyocytes

  Chenchen Zhu, et al., bioRxiv - Genetics 2021

  Quote: ... supplemented with 6μM CHIR (TOCRIS 4953). On day 6 ...
• Single-molecule, full-length transcript isoform sequencing reveals disease mutation-associated RNA isoforms in cardiomyocytes

  Chenchen Zhu, et al., bioRxiv - Genetics 2021

  Quote: ... media was changed to E8 with Rock inhibitor (Tocris Cat. No. 1254). For each well ...
• CRISPR Del/Rei: A simple, flexible and efficient pipeline for scarless genome editing

  Marah H. Wahbeh, et al., bioRxiv - Genetics 2021

  Quote: ... The media was supplemented with 10 μM ROCK inhibitor (Y-27632 dihydrochloride, Tocris #1254) on days of thawing ...
• SARS-CoV-2 spike protein expressing epithelial cells promotes senescence associated secretory phenotype in endothelial cells and increased inflammatory response

  Keith Meyer, et al., bioRxiv - Immunology 2021

  Quote: ... and AT1 receptor antagonist Candesartan cilexetil (Tocris) were used in this study ...
• Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells

  Connie L. Jiang, et al., bioRxiv - Genomics 2021

  Quote: ... we changed the medium to RPMI/B27-insulin supplemented with 1uM Xav 939 (Tocris Bioscience, cat. 3748), and incubated cells for another 48 hours ...
• Blocking the Rac1-TRPC5 pathway protects human podocytes

  Yiming Zhou, et al., bioRxiv - Cell Biology 2021

  Quote: ... Vitamin D3 (100 nM, Tocris Bioscience, #4156), and Retinoic Acid (100 µM ...
• Oxidant-Resistant LRRC8A/C Anion Channels Support Superoxide Production by Nox1

  Hyehun Choi, et al., bioRxiv - Cell Biology 2021

  Quote: ... DCPIB (30 μM; Tocris Bioscience, Bristol UK) was added daily from freshly thawed 30 mM (DMSO ...
• Asymmetric Contraction of Adherens Junctions arises through RhoA and E-cadherin feedback

  Kate E. Cavanaugh, et al., bioRxiv - Cell Biology 2021

  Quote: ... or 100uM NSC23766 (Tocris) 24-48 hours before optogenetic activation ...
• Rho and F-actin self-organize within an artificial cell cortex

  Jennifer Landino, et al., bioRxiv - Cell Biology 2021

  Quote: Latrunculin B powder (Tocris Bioscience) was resuspended in DMSO (Sigma ...
• Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation

  Francesca Alessandrini, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stimulated with HDM or the known AhR agonist FICZ (5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde, Tocris Bioscience ...
• Activation of the Zinc-sensing receptor GPR39 promotes T cell reconstitution after hematopoietic stem cell transplant

  Lorenzo Iovino, et al., bioRxiv - Immunology 2021

  Quote: For the administration of TC-G 1008 (Tocris, Bristol, UK.), we followed a micropipette-guided drug administration protocol67 ...
• High glucose enhances antigen-independent CTL killing via TRAIL

  Wenjuan Yang, et al., bioRxiv - Immunology 2021

  Quote: ... Calcipotriol (TOCRIS), DMSO (Merck) ...
• Non-canonical Hedgehog signaling through L-type voltage gated Ca²⁺ channels controls CD8⁺ T cell killing

  Joachim Hanna, et al., bioRxiv - Immunology 2021

  Quote: In vitro tamoxifen was given as 4-hydroxytamoxifen (4-OH-Tamoxifen or OHT) (TOCRIS, Cat no. 3412) solubilized in DMSO (Life Technologies ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... ZCL278 (4794, Tocris, 25 μM), EHop016 (6248 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... ebselen (5245, Tocris,, 50 μM), edelfosine (3022 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... cAMPS-Rp (13371, Tocris, 10 μM), H89 (2910 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... rhosin (5003, Tocris, 25 μM), and nocodazole (S2775 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... EHop016 (6248, Tocris, 12.5 μM), rhosin (5003 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... ESI 09 (4773, Tocris, 5 μM), cAMPS-Rp (13371 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... U73122 (1268, Tocris, 5 μM), latrunculin (ab144290 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... ionomycin (1704, Tocris, 1 μM), and cyclopiazonic acid (CPA ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... edelfosine (3022, Tocris, 40 μM), U73122 (1268 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... H89 (2910, Tocris, 10 μM), PD0325901 (04-0006 ...
• G protein-coupled receptor signaling regulates ER-mitochondria contacts

  Youngshin Lim, et al., bioRxiv - Cell Biology 2021

  Quote: ... sotalol (0952, Tocris, 250 μM), actinomycin D (A9415 ...
• High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning

  Angela M. Getz, et al., bioRxiv - Neuroscience 2021

  Quote: ... with 1 µM tetrodotoxin citrate (TTX; Tocris, 1069), or treated for 3 min with 30 µM N-Methyl-D-aspartic acid (NMDA ...
• Social preference in rats not impacted by posterior parietal activity despite overall changes in familiarity-based social behavior

  Taylor B. Wise, et al., bioRxiv - Animal Behavior and Cognition 2021

  Quote: ... Neurotoxic lesions were established through 0.09M NMDA (Tocris Bioscience, Minneapolis, MN) in 0.1M phosphate buffer ...
• Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress

  Anja Karlstaedt, et al., bioRxiv - Systems Biology 2021

  Quote: ... D-2-hydroxyglutarate (D2-HG, 0 to 1.0 mmol/L; Tocris Bioscience ...
• KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

  Alexandra D’Oto, et al., bioRxiv - Cancer Biology 2021

  Quote: Materials: GSK J1 is purchased from Tocris (Bristol ...
• KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

  Alexandra D’Oto, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Daminozide is purchased from Tocris (Bristol ...
• MiR-137 and miR-122, two outer subventricular zone-enriched non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation

  Ugo Tomasello, et al., bioRxiv - Evolutionary Biology 2021

  Quote: ... Spontaneous excitatory postsynaptic currents (sEPSCs) were recorded at Vh=-70 mV 1 µM of SR95531 hydrobromide (Tocris, Cat no. 1262) was bath applied to block inhibitory neurotransmission ...