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Citations for Tocris :
351 - 378 of 378 citations for 6 4 MORPHOLINYL PYRAZINAMINE since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2022Quote: ... we used a cocktail of the mGluR-4 antagonist [0.5 mM MSOP: (RS)-α-methylserine-O-phosphate obtained from Tocris Biosciences] with either umami at 300 mM or MSGa at 600 mM ...
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bioRxiv - Neuroscience 2024Quote: ... 1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide (WS-12) was purchased from Tocris Bioscience and prepared in a DMSO stock (20 mM) ...
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bioRxiv - Cancer Biology 2022Quote: ... and plated at 60,000 cells/cm2 in N2B27 medium supplemented with 20 ng/ml of FGF2 (Cat# 233-FB/CF, R&D) and 4 μM of CHIR 99021 (Cat# 4423, Tocris) and 10 μM of Rock Inhibitor (Y-27632 ...
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bioRxiv - Neuroscience 2023Quote: ... and (3-chloro-4-fluoro-N-[(4-([2-(phenylcarbonyl)hydrazino]carbonyl) phenyl)methyl]benzene-sulfonamide) (TCN-201) (Hansen et al., 2012)were obtained from Tocris Bioscience ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were then rinsed with 3x with PBS before fixation with 4% paraformaldehyde in PBS with 10 μg/ml Hoechest 33342 (Tocris) for 30 min at RT ...
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bioRxiv - Neuroscience 2024Quote: ... 2 mM stock made in water) and 2 mM 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI caged glutamate) (Tocris Bioscience ...
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bioRxiv - Neuroscience 2024Quote: ... was set to 720 nm and used to uncage 4-Methoxy-7-nitroindolinyl-caged-L-glutamate (MNI-caged glutamate, Tocris). Up to four spines in separate regions of interest (ROI ...
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bioRxiv - Neuroscience 2022Quote: ... 12-well plates at 3-4 × 105 cells/well in mTeSR1 with 10 µM rho-kinase inhibitor (Y-27632; Tocris, 1254). Medium without the inhibitor was replaced daily until the cells reach 80-100% confluency ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Developmental Biology 2019Quote: ... From day 2 to day 4 the medium was additionally supplemented with BMP and TGFβ inhibitors (Noggin, Peprotech and SB431542, Tocris Bioscience). Treatment with MEK inhibitor (PD184352 ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Neuroscience 2022Quote: ... Intervet AB, Sweden), PCP (phencyclidine hydrochloride, 5 mg/kg, Lipomed AG, Switzerland) or amphetamine (d-amphetamine hydrochloride, 4 mg/kg, Tocris, UK) and recorded for another 60-120 minutes ...
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bioRxiv - Biochemistry 2022Quote: ... Positive clones were analyzed by Sanger sequencing with primers #3 and #4 (Integrated DNA Technologies, Supplementary Table S5) and degradation upon dTAG-13 (Tocris, 6605) treatment was confirmed by Western Blot by a-Chaf1a antibody (65) ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Neuroscience 2024Quote: ... The cell suspension was then centrifuged at 1,200 rpm for 4 minutes and resuspended in mTeSR medium supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris Cat # 1254) at a concentration of 10,000 cells per 100 µL or 1 million cells per 10 mL ...
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bioRxiv - Pharmacology and Toxicology 2019Quote: ... The P2Y2R antagonist AR-C118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide) was obtained from Tocris (Abingdon, UK). Subsequent dilutions of receptor ligand and other reagents were made in Krebs-Ringer Glucose phosphate buffer (KRG ...
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bioRxiv - Neuroscience 2020Quote: ... 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester (KN-62; Tocris and HelloBio); D-AP5 (HelloBio) ...
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bioRxiv - Neuroscience 2020Quote: ... co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris; 20 μM) (n=13) ...
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bioRxiv - Neuroscience 2019Quote: ... (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid (TFB-TBOA) was purchased from Tocris (Minneapolis, MN; Cat# 2532). All other chemicals were purchased from MilliporeSigma (Burlington ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... as well as the P2Y2R antagonist AR-C118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide) were obtained from Tocris (Abingdon, UK). Subsequent dilutions of receptor ligand and other reagents were made in Krebs-Ringer Glucose phosphate buffer (KRG ...
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bioRxiv - Neuroscience 2023Quote: ... Drug treatments correspond to a single dose of cocaine hydrochloride at 20 mg/kg (Medisca, cat# 53-21-4, Canada) or D-amphetamine sulfate at 5 mg/kg (Tocris, 2813, UK) at doses known to increase locomotion87 ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...
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bioRxiv - Neuroscience 2021Quote: ... and MNI-caged-L-glutamate ((S)-α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid) were purchased from Tocris (Bristol, UK). Rhod-2 tripotassium salt was purchased from AAT Bioquest (Sunnyvale ...
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bioRxiv - Physiology 2024Quote: ... Drugs were added from the following stock solutions: (2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboximide (WS-12, Tocris #3040, Bio-Techne Ltd, Abingdon, UK) 5 mM in ethanol ...
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bioRxiv - Neuroscience 2023Quote: ... we tested effects of an inhibitor (the spider toxin GsMTX 4; Tocris #4912 stock 50 μM in DMSO and the Piezo1 channel activator Yoda1 (Tocris 6586 10 and 20 uM, stock 20 mM in DMSO).