Labshake search

301 - 350 of 1105 citations for L β Homo β 2 hydroxyphenyl glycine; R 3 Amino 3 2 hydroxyphenyl propanoic acid since 2020

• Layer 1 NDNF⁺ Interneurons Control Bilateral Sensory Processing in a Layer-dependent Manner

  Rasmus Vighagen, et al., bioRxiv - Neuroscience 2021

  Quote: ... In some cases 3 mg/ml biocytin (Tocris) was added in the recording solution ...
• Microglial amyloid beta clearance is driven by PIEZO1 channels

  Henna Konttinen, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3) a selective PIEZO1 agonist Yoda1 (5586, Tocris). For pressure pulse stimulation ...
• Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

  John M. Viola, et al., bioRxiv - Bioengineering 2023

  Quote: ... which included 3 µM CHIR 99021 (Tocris, 4423) +/- 10 µM Y27632 (StemCell Technologies ...
• Neural tube organoids self-organise floorplate through BMP-mediated cluster competition

  Teresa Krammer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... N2B27 was supplemented with 3 µM CHIR99021 (Tocris), 1 µM PD0325901 (Tocris ...
• Disentangling cell-intrinsic and extrinsic factors underlying gene expression evolution

  Alexander L. Starr, et al., bioRxiv - Evolutionary Biology 2024

  Quote: ... and 3 μM GSK3 inhibitor CHIR99021 (Tocris: 4423). Undifferentiated tdTomato-labelled rat ESCs were maintained in N2B27 medium containing 1 μM MEK inhibitor PD0325901 ...
• Experience instructs the refinement of feature-selectivity in the mouse primary visual thalamus

  Takuma Sonoda, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 mg/kg clozapine N-oxide (CNO) (Tocris) was injected subcutaneously ...
• The human glucocorticoid receptor variant rs6190 promotes blood cholesterol and atherosclerosis

  Hima Bindu Durumutla, et al., bioRxiv - Physiology 2024

  Quote: ... and 3 µM CHIR99021 (Cat #4423, Tocris Bioscience). Following 24-h treatment ...
• Reconstructing signaling history of single cells with imaging-based molecular recording

  Kai Hao, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... together with 3 µM of CHIR (TOCRIS, 4423) or 64 ng/ml of BMP2 (R&D ...
• Reconstructing signaling history of single cells with imaging-based molecular recording

  Kai Hao, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... together with 3 µM of CHIR (TOCRIS, 4423) or 64 ng/ml of BMP2 (R&D ...
• GLUT1 ablation in astrocytes paradoxically improves central and peripheral glucose metabolism via enhanced insulin-stimulated ATP release

  Carlos G. Ardanaz, et al., bioRxiv - Neuroscience 2022

  Quote: ... or 20 μM 2-methylthyo-adenosine-5’-triphosphate (2-MeSATP, Tocris, 1062) over a 5-min period ...
• Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

  Constanze Depp, et al., bioRxiv - Neuroscience 2021

  Quote: ... Amyloid plaques were stained by the β-sheet dye Methoxy-X04 (4 μg/ml in 50% ethanol, Tocris) for 30 min at RT and contrasting in 50% ethanol ...
• Association of a Common Genetic Variant with Parkinson’s Disease is Propagated through Microglia

  R. G. Langston, et al., bioRxiv - Neuroscience 2021

  Quote: ... MLi-2 (Tocris #5756) was reconstituted in DMSO to a stock concentration of 10mM ...
• HCN1 channels mediate mu opioid receptor long-term depression at insular cortex inputs to the dorsal striatum

  Braulio Munoz, et al., bioRxiv - Neuroscience 2022

  Quote: ... WIN55,212-2 (1038, Tocris), and Torin 2 (4248 ...
• LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2020

  Quote: ... MLi-2 (Tocris, 5756) was used at 1 µM ...
• Cannabis sativa Terpenes are Cannabimimetic and Provide Support for the Entourage Effect Hypothesis

  Justin E. LaVigne, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: WIN55,212-2 (Tocris, #1038), α-Humulene (Sigma Aldrich ...
• Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38

  Ceryl Tan, et al., bioRxiv - Cell Biology 2020

  Quote: ... Torin-2 (Tocris 4248), rapamycin (CalBiochem 553211) ...
• LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

  Riccardo Sirtori, et al., bioRxiv - Neuroscience 2024

  Quote: ... DMH1 (2 μM, Tocris) and SB431542 (2 μM ...
• CDKN1B (p27^kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors

  Elad Horwitz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... AKTi-1/2 (Tocris), MK-2206 (VWR) ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... 2 µM Dorsomorphin (TOCRIS) and 2 µM XAV939 (Stemgent) ...
• NOTCH3 signalling controls human trophoblast stem cell expansion and differentiation

  Bianca Dietrich, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 µM CHIR99021 (Tocris) and 5µM Y27632 (Santa Cruz) ...
• Ca²⁺-sensing receptor regulates neuronal excitability via Kv7 channel and G_i/o protein signalling

  Nontawat Chuinsiri, et al., bioRxiv - Physiology 2023

  Quote: ... 2 μM PD0332991 (Tocris), 10 ng/ml human BDNF (Miltenyi Biotec) ...
• An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes

  Leonard Yoon, et al., bioRxiv - Cell Biology 2023

  Quote: ... 2 µM Dorsomorphin (Tocris), 10 µM SB-431542 (Tocris) ...
• Genetically edited human placental organoids cast new light on the role of ACE2 in placental development

  Anya L. Arthurs, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 2 µM CHIR99021 (Tocris) and 5 µM Y27632 (Santa Cruz).
• A trimeric USP11/USP7/TCEAL1 complex stabilizes RNAPII during early transcription to sustain oncogenic gene expression

  Markus Dehmer, et al., bioRxiv - Cancer Biology 2024

  Quote: ... NVP-2 (Tocris Biosciences), Flavopiridol (Sigma-Aldrich) ...
• Enhanced food motivation in obese mice is controlled by D1R expressing spiny projection neurons in the nucleus accumbens

  Bridget A Matikainen-Ankney, et al., bioRxiv - Neuroscience 2022

  Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
• Gallein and isoniazid act synergistically to attenuate Mycobacterium tuberculosis growth in human macrophages

  Ramesh Rijal, Richard H. Gomer, bioRxiv - Microbiology 2024

  Quote: To investigate the impact of gallein (3’,4’,5’,6’-Tetrahydroxyspiro[isobenzofuran-1(3H),9’- (9H)xanthen]-3-one) (Cat#3090, Tocris, Minneapolis, MN) and/or INH on Mtb growth ...
• Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

  Antigoni Gogolou, et al., bioRxiv - Developmental Biology 2021

  Quote: ... N2B27 medium was supplemented with CHIR99021 (3 μM, Tocris), FGF2 (20 ng/ml ...
• Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

  Katarina Stoklund Dittlau, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 3 μM CHIR99021 (Tocris Bioscience, Cat N° 4423) for 2 days with medium changes every day (=day 0-1) ...
• Monosodium Urate Crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

  Isidoro Cobo, et al., bioRxiv - Cell Biology 2021

  Quote: ... 3 μM of p38 MAPK inhibitor SB203580 (Tocris, #1202) or NLRP3 inflammasome inhibitor MCC950 (1uM ...
• Adolescent frontal top-down neurons receive heightened local drive to establish adult attentional behavior in mice

  Elisa M Nabel, et al., bioRxiv - Neuroscience 2020

  Quote: Clozipine-N-Oxide dihydrochloride (CAS2250025-93-3, Tocris Biosciences) was injected intraperitoneally (i.p. ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... directly into N2B27 medium containing CHIR99021 (3 µM, Tocris), FGF2 (20 ng/ml ...
• Metabotropic glutamate group II receptor activation in the dorsal striatum suppresses the motivation for cocaine in rats

  Shaun Yon-Seng Khoo, Anne-Noël Samaha, bioRxiv - Neuroscience 2022

  Quote: ... The mGlu2/3 agonist LY379268 was obtained from Tocris (Cat# ...
• Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish

  Fusun Doldur-Balli, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Zatebradine hydrochloride (Tocris, Cas Registry No. 91940-87-3) and ZD7288 (Tocris ...
• Mouse brain organoids model in vivo neurodevelopment and function and capture differences to human

  Daniel J Lloyd-Davies Sánchez, et al., bioRxiv - Neuroscience 2024

  Quote: ... EBs were treated with 3 μM CHIR (TOCRIS, #4423) and 20 ng/ml BMP4 (Peptotech ...
• Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations

  Chuyu Chen, et al., bioRxiv - Neuroscience 2020

  Quote: ... and the Mai Tai eHP was tuned to 725nm for photoactivation of recirculated caged MNI-L-glutamate (2 mM, Tocris)57,58 ...
• The α4 nicotinic acetylcholine receptor is necessary for the initiation of organophosphate-induced neuronal hyperexcitability

  Peter M. Andrew, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... the α4-selective nAChR antagonist dihydro-β-erythroidine hydrobromide (DHβE; 5 mg/kg in sterile saline; Tocris, Bristol, UK), or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA ...
• An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

  Elisabetta Furlanis, et al., bioRxiv - Neuroscience 2024

  Quote: ... The cholinergic nature of these inputs was confirmed by application of 10 uM Dihydro-β-erythroidine hydrobromide (DhβE, Tocris) and 10 uM Methyllycaconitine (MLA ...
• Intraneuronal chloride levels encode tiredness in cortex

  Hannah Alfonsa, et al., bioRxiv - Neuroscience 2021

  Quote: ... or glycine (Tocris Bioscience, 100 μM) via a patch pipette placed in the vicinity of the cell soma and connected to a picospritzer (5–10 psi for 20–40 ms ...
• Neuromesodermal Progenitors Advance Network Formation of Spinal Neurons and Support Cells in Neural Ribbons In Vitro and Unprotected Survival in a Rat Subacute Contusion Model

  Zachary T. Olmsted, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2 μM CHIR99021 (Tocris Bioscience), 10 μM DAPT (Millipore Sigma) ...
• The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity

  E. Werner, et al., bioRxiv - Cell Biology 2022

  Quote: ... 2 μM dorsomorphin (Tocris, 3093) and 2 μM A-83 (Tocris ...
• Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis

  Vukasin M. Jovanovic, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 2 µM forskolin (1099, Tocris), 200 nM phorbol-12 myristate-13 acetate (1201 ...
• A cell-based platform for oxidative stress monitoring in motor neurons using genetically encoded biosensors of H₂O₂

  Elizaveta I. Ustyantseva, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 2 μM DMH1 (Tocris) for 6 days ...
• TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons

  Ki Bum Um, et al., bioRxiv - Neuroscience 2021

  Quote: ... 2-APB (Tocris, Cat.#: 1224), CPP (Tocris ...
• Pharmacological insights into safety and efficacy determinants for the development of adenosine receptor biased agonists in the treatment of heart failure

  Patricia Rueda, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... 2’Me-CCPA (Tocris, 2281), MRS1754 (Tocris ...
• Identification and Characterization of Stem Cells in Mammalian Esophageal Stratified Squamous Epithelia

  Yanan Yang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Wnt inhibitor IWP-2(TOCRIS) and Srfp-2(R&D Systems ...
• Lysosomal positioning regulates Rab10 phosphorylation at LRRK2-positive lysosomes

  Jillian H. Kluss, et al., bioRxiv - Cell Biology 2021

  Quote: ... MLi-2 (Tocris, cat #5756) was used at 1 μM in DMSO for 90 min ...
• A peptidergic amygdala microcircuit modulates sexually dimorphic contextual fear

  AK Rajbhandari, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2 mg/ml biocytin (Tocris) was dissolved in the intracellular solution and cells were dialyzed for 20 minutes ...
• Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex

  Stephen D. Glasgow, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 2-Aminoethoxydiphenylborane (1224, Tocris) in DMSO ...
• Autologous humanized mouse models of iPSC-derived tumors allow for the evaluation and modulation of cancer-immune cell interactions

  Gaël Moquin-Beaudry, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 4 μM IWP-2 (Tocris), and 1 μM A83-01 (Tocris) ...
• Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells

  Yuka Sakata, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 2 μM SU-5402 (Tocris), and 10 μM DAPT (Tocris) ...