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301 - 350 of 1377 citations for Benzyl 2 3 4 5 6 d5 dimethyltetradecylammonium Bromide since 2020

• A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

  Kunimichi Suzuki, et al., bioRxiv - Neuroscience 2020

  Quote: ... CGP 55845 (3 μM, Tocris), and tetrodotoxin (Tocris ...
• Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context

  Luigi Russo, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 3 μM CHIR99021 (Tocris) or 50 ng/ml Activin A (Peprotech) ...
• Kinetochores respond to subtle changes in the stability of microtubule attachments

  Jessica D. Warren, et al., bioRxiv - Cell Biology 2021

  Quote: ... ZM447439 (3 μM; Tocris Bioscience), Okadaic Acid (100 nM ...
• C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein

  Yuma Kato, et al., bioRxiv - Neuroscience 2021

  Quote: ... 3 μM SB431542 (Tocris, UK), and 3 μM CHIR99021 (Focus Biomolecules ...
• Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord

  Kalaimakan Hervé Arulkandarajah, et al., bioRxiv - Neuroscience 2020

  Quote: ... gabazine (3 μM, Tocris, USA), CNQX Disodium (20 μM ...
• LTD at amygdalocortical synapses as a novel mechanism for hedonic learning

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Altered Thalamocortical Signaling in a Mouse Model of Parkinson’s Disease

  Olivia K. Swanson, David Richard, Arianna Maffei, bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Erev[Cl−] = −49.8mV)) ...
• CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cells development

  Young Sun Hwang, M. Andrés Blanco, Kotaro Sasaki, bioRxiv - Developmental Biology 2022

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience) and 10 μM of a ROCK inhibitor ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 3 μM CHIR99021 (Tocris)) was added to each lower chamber ...
• Inhibitory gating of thalamocortical inputs onto rat gustatory insular cortex

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Ca²⁺-sensing receptor regulates neuronal excitability via Kv7 channel and G_i/o protein signalling

  Nontawat Chuinsiri, et al., bioRxiv - Physiology 2023

  Quote: ... 3 μM CHIR-99021 (Tocris), 200 μM L-ascorbic acid (Merck) ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... CHIR99021 3 μM (4423, Tocris), holo-transferrin 10 μg/ml (T0665 Sigma) ...
• Design, implementation, and functional validation of a new generation of microneedle 3D high-density CMOS multi-electrode array for brain tissue and spheroids

  Lisa Mapelli, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 μM TTX (tetrodotoxin, Tocris) was added to the Krebs solution ...
• An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris). In base control strategy #14 ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... IPA-3 (1 μM; Tocris), BDP-9066 (1 μM ...
• Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons

  Yoshifumi Sonobe, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 3 µM CHIR99021 (Tocris Bioscience), 2 µM DMH1 (Tocris Bioscience) ...
• Electron microscopic analysis of the influence of iPSC-derived motor neurons on bioengineered human skeletal muscle tissues

  Christine T. Nguyen, et al., bioRxiv - Cell Biology 2023

  Quote: ... 3 μM CHIR99021 (Tocris 4423) and 200 μM ascorbic acid (Sigma-Aldrich ...
• Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation

  Sina Schumacher, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 µM CHIR99021 (Tocris), referred to as 2i + LIF.33 N2B27 was prepared as a 1:1 mixture of DMEM/F12 and Neuropan Basal Medium (both from PAN Biotech) ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• Modulation of sweet preference by neurosteroid-sensitive, δ-GABA_A receptors in adult mouse gustatory insular cortex

  Priscilla E Yevoo, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (reversal potential (Vrev)[Cations] = 10mV) ...
• Differential inhibition of GABA release from mouse hippocampal interneuron subtypes by the volatile anesthetic isoflurane

  Iris A. Speigel, Hugh C. Hemmings Jr, bioRxiv - Neuroscience 2020

  Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) to block glutamatergic signaling (both from Tocris, Bristol, UK). Experiments involving tetrodotoxin (TTX ...
• Serotonergic drugs inhibit CHIKV infection at different stages of the cell entry pathway

  Ellen M. Bouma, et al., bioRxiv - Microbiology 2020

  Quote: ... 5-nonyloxytryptamine oxalate (5-NT) (Tocris, Bristol, United Kingdom) was diluted to a 5mM stock concentration in DMSO (Merck) ...
• AMPA receptor anchoring at CA1 synapses is determined by an interplay of N-terminal domain and TARP γ8 interactions

  Jake F. Watson, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2 μM 2-chloroadenosine (Tocris Cat#3136) was added to aCSF to dampen epileptiform activity ...
• Investigation of adenosine A1 receptor mediated β-arrestin 2 recruitment using a split-luciferase assay

  Luisa Saecker, Hanns Häberlein, Sebastian Franken, bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX; Tocris, 102146-07-6), 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino] ethyl]-benzenepropanoic acid ...
• Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions

  Anna Bodzęta, et al., bioRxiv - Neuroscience 2021

  Quote: ... The following chemical reagents were used: 4-aminopyridine (4-AP, TOCRIS, #940), ADX 71743 (TOCRIS ...
• Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure

  Jerome AJ Becker, et al., bioRxiv - Neuroscience 2020

  Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
• Somatic Depolarization Enhances Hippocampal CA1 Dendritic Spike Propagation and Distal Input Driven Synaptic Plasticity

  Tobias Bock, Steven A. Siegelbaum, bioRxiv - Neuroscience 2021

  Quote: ... 4-AP (Tocris, UK) was stored as a stock solution of 100 mM in ACSF at -20°C and applied to the bath at 5 mM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CHIR99021 (4 μM; Tocris), FGF2 (20 ng/mL ...
• Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation

  Safia A. Essien, et al., bioRxiv - Cell Biology 2023

  Quote: ... 4-IPP (Tocris, 3429), and Brefeldin A (Millipore-Sigma ...
• ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis

  Kathryn M. Yammine, et al., bioRxiv - Genetics 2024

  Quote: ... 4 μM CHIR99021 (Tocris), 20 ng/mL FGF2 (PeproTech ...
• Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling

  Richard Drexler, et al., bioRxiv - Neuroscience 2024

  Quote: ... 4-DAMP (10μM, Tocris) and vehicle (DMSO ...
• Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II

  Kathryn M. Yammine, et al., bioRxiv - Cell Biology 2024

  Quote: ... 4 μM CHIR99021 (Tocris), 20 ng/mL FGF2 (PeproTech ...
• A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics in vitro and in vivo

  Ao Dong, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5-HT (Tocris), His (Tocris) ...
• Augmentation of extracellular ATP synergizes with chemotherapy in triple negative breast cancer

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 5-BDBD (Tocris), ENPP1 inhibitor C (Cayman Chemical ...
• A toolkit of highly selective and sensitive genetically encoded neuropeptide sensors

  Huan Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... 5 Desmopressin (Tocris), 1 NTS ...
• New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

  Fangmiao Sun, et al., bioRxiv - Neuroscience 2020

  Quote: ... 5-HT (Tocris), histamine (Tocris) ...
• An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

  Zhaofa Wu, et al., bioRxiv - Neuroscience 2021

  Quote: ... 5-HT (Tocris), HA (Tocris) ...
• Improved dual-color GRAB sensors for monitoring dopaminergic activity in vivo

  Yizhou Zhuo, et al., bioRxiv - Neuroscience 2023

  Quote: ... 5-HT (Tocris), HA (Tocris) ...
• The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 5-BDBD (Tocris) and heparan sodium sulfate (Sigma).
• Sex-specific Effects of the Endocannabinoid Agonist 2-Arachidonoylglycerol on Sleep and Circadian Disruptions during Fentanyl Withdrawal

  Mackenzie C. Gamble, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2-Arachidonoylglycerol (2-AG) was obtained from Tocris Biosciences (Cat ...
• Experience Shapes Chandelier Cell Function and Structure in the Visual Cortex

  Koen Seignette, et al., bioRxiv - Neuroscience 2023

  Quote: ... in combination with potassium channel blocker 4-aminopyridine (4-AP, 1 mM, Tocris) to facilitate transmitter release at monosynaptic connections from RSC to ChC and recorded the PSP amplitudes (Figure 1H) ...
• Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells

  Jose Ernesto Canton-Josh, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 μM Pyr-3 (Tocris,3753), 1 mM MNI-caged-L-glutamate ...
• Single-cell profiling of transcriptome and histone modifications with EpiDamID

  Franka J. Rang, et al., bioRxiv - Genomics 2021

  Quote: ... 3 μM CHIR99021 (Tocris, SML1046-5MG), 1000 U/mL ESGRO mLIF ...
• 3D genome organization around nuclear speckles drives mRNA splicing efficiency

  Prashant Bhat, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 3 μM CHIR 99021 (Tocris, 4423), and 50 nM PI 103 (Tocris ...
• Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A

  Robert Prior, et al., bioRxiv - Neuroscience 2023

  Quote: ... 3 mM CHIR-99021 (Tocris Biosciences), and 20 µM SB 431542 (Tocris Biosciences) ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... and CHIR99021 3 μM (4423, Tocris). After 3 days ...
• Recording morphogen signals reveals origins of gastruloid symmetry breaking

  Harold M. McNamara, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris, 4423).
• Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

  Kizito-Tshitoko Tshilenge, et al., bioRxiv - Neuroscience 2022

  Quote: ... GABA (3 mM, Tocris Bioscience, 0344), CaCl2 (1.8 mM ...
• Identification of the main barriers to Ku accumulation in chromatin

  Madeleine Bossaert, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or NU-7441 (3 µM, Tocris) were added when specified 1 h prior to irradiation ...