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Citations for Tocris :
301 - 350 of 1667 citations for 6 oxo 1 phenyl 1 4 5 6 tetrahydro pyridazine 3 carboxylic acid since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Molecular Biology 2023Quote: ... BI stands for Broccoli aptamer ligand (5Z)-3-(1H-Benzimidazol-7-ylmethyl)-5-[(3,5-di-fluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-4H-imidazol-4-one dihydrochloride) (Cat. No. 7466, Tocris) (14) ...
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bioRxiv - Neuroscience 2024Quote: ... CACNA1A+/− networks on MEA at DIV51 were treated with 20 µM 4-aminopyridine (4-AP; Tocris, #504-24-5) and recorded for 30 minutes after the compound was added ...
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bioRxiv - Neuroscience 2019Quote: ... and 5 µg/ml Bovine Serum Albumin) containing 4 µM CHIR99021 (Tocris), 3 µM SB431542 (Sigma) ...
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bioRxiv - Cell Biology 2020Quote: ... 5 mg/kg BW for 2,3-bis(4-Hydroxyphenyl)-propionitrile (DPN, Tocris), or vehicle ...
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bioRxiv - Genomics 2023Quote: ... 2,3-Bis(4-hydroxyphenyl)propionitrile (DPN, 5 mg/kg body weight, Tocris) and 4-(2-(3,5-dimethylisoxazol-4-yl)-1H-indol-3-yl)phenol (DIP ...
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bioRxiv - Neuroscience 2021Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247; 5 μM SR-95531, Tocris, 1262; 1 μM CGP-55845, Tocris, 1248) were included in the recording solutions.
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bioRxiv - Neuroscience 2020Quote: ... mEPSCs were recorded for 5 min in the presence of 1 μM tetrodotoxin (Tocris), 10 μM CPP (Tocris) ...
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bioRxiv - Neuroscience 2023Quote: ... (-)-quinpirole HCl (QUIN; 0.05 mg/kg, 1 mg/kg or 5 mg/kg; Tocris), raclopride HCl (RACLO ...
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bioRxiv - Biochemistry 2021Quote: ... were recorded at 32°C in an interface-type chamber (perfusion rate 4.5 mL per minute) and elicited by applying kainic acid (100 nmol L-1, Tocris). The oscillations were stabilized for 20 min before any recordings ...
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Safety and efficacy of C9ORF72-repeat RNA nuclear export inhibition in amyotrophic lateral sclerosisbioRxiv - Systems Biology 2021Quote: ... supplemented with SMAD inhibitors (DMH-1 2 µM; SB431542-10 µM and CHIR99021 3 µM [ [Tocris]). The medium was changed every day for 6 days ...
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bioRxiv - Neuroscience 2021Quote: ... 3-((±)2-carboxypiperazin-4yl) propyl-1-phosphate (CPP, NMDA receptor antagonist, 20 μM; Tocris Bioscience, UK) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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bioRxiv - Cell Biology 2020Quote: ... the γ-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine1,1-dimethylethyl ester (DAPT) (Tocris) was added at a concentration of 5 μM ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2020Quote: ... The following agents were used: L-(+)-2-amino-4-phophonobutyric acid (L-AP4; 20μM; Tocris Bioscience, catalog #0103), D-(-)-2-amino-5-phophonopentanoic acid (D-AP5 ...
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bioRxiv - Neuroscience 2021Quote: ... washed with 4-5 ml ice cold PBS supplemented with 0.5 % BSA (Tocris), and collected by centrifugation for 10 min (300 g) ...
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bioRxiv - Neuroscience 2020Quote: ... medium was exchanged every 3-4 days with RGC induction media containing: DAPT (3uM, Tocris), 10μM Rock inhibitor (Y27632) ...
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bioRxiv - Systems Biology 2023Quote: ... Cells were assayed by flow cytometry after 5 days of 1 µg/mL doxycycline (Tocris) treatment for repressors and 2 days of doxycycline for activators ...
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bioRxiv - Biophysics 2023Quote: ... were maintained in serum-free N2B27 medium containing 2i (1 mM PD0325901and 3 mM CHIR99021, both Tocris) and LIF (10 mg/ml ...
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Developmental Biology 2021Quote: ... (15) ESC were grown in N2B27 media supplemented with 2i/LIF (1 mM PD0325901, 3 mM CHIR99021, both from Tocris and 1:500 LIF, made in house). N2B27 media consisted of a 1:1 mix of DMEM/F12 and Neurobasal Medium ...
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Developmental Biology 2023Quote: ... N6,2’-O-Dibutyryladenosine 3’,5’-cyclic monophosphate sodium salt (DB-cAMP, TOCRIS Cat. No.: 1141), 8-(4-Chlorophenylthio)-N6-phenyladenosine-3’,5’-cyclic monophosphate sodium salt (8C6P-cAMP ...
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bioRxiv - Cell Biology 2021Quote: ... B/D medium was supplemented during submerged culture with 1 nM EC23 (light-stable retinoic acid receptor agonist; Tocris, Abingdon, UK). After confluence was reached ...
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bioRxiv - Neuroscience 2020Quote: ... Readings were taken before and 3–4 min after application of 20 μM 2-AG (Tocris) to activate CB1R or the eCB sensor.
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bioRxiv - Microbiology 2022Quote: NADA (3-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-alanine hydrochloride) was synthesized by Tocris following the published protocol (31) ...
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bioRxiv - Cell Biology 2022Quote: At day 0 cells were treated with 5 nM 4-Hydroxytamoxifen (+HOT) (Tocris, 3412) or with vehicle (-HOT ...
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bioRxiv - Developmental Biology 2021Quote: ... paraxial mesoderm (1 day; 20 ng/ml FGF2, 3 µM CHIR99021, 2 µM SB505124 [cat. num. 3263; Tocris Bioscience ...
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bioRxiv - Immunology 2022Quote: ... or a CD73 inhibitor (0–1 μM) (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) plus ATP (100 μM ...
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bioRxiv - Neuroscience 2020Quote: ... Membranes were blocked for 1 hour at RT on a shaker in 5% BSA (Tocris, 5217) with 0.1% Tween-20 (Bio-Rad ...
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bioRxiv - Developmental Biology 2021Quote: ... early somite (1 day; 2 µM SB505124, 4 µM dorsomorphin, 500 nM PD173074 [cat. num. 3044; Tocris Bioscience ...
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bioRxiv - Neuroscience 2019Quote: ... To block NMDA receptors we used D- (-)-2-Amino-5-phosphonopentanoic acid (D-AP5, Tocris, 10 μM final concentration). To block glycinergic inhibition ...
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bioRxiv - Neuroscience 2020Quote: ... 20 μM 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 20 μM D-(-)-2-amino-5-phosphopentanoic acid (D-AP5) (Tocris Bioscience) to block glycine- ...
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bioRxiv - Molecular Biology 2021Quote: ... 1 µM IDE-1 (Tocris), 0.2% (v/v ...
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bioRxiv - Developmental Biology 2023Quote: ... 1 μM DMH-1 (Tocris) and 3 μM CHIR99021 (Tocris) ...
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bioRxiv - Developmental Biology 2021Quote: ... From passage 3 cells were grown NMP differentiation medium supplemented with 5 μM Y-27632 (Tocris). Human iPSCs were found to detach more readily than hESCs ...
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bioRxiv - Cell Biology 2021Quote: 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride (NE-100 hydrochloride) was purchased from Tocris (3133). Stock and work solutions were prepared using 100% dimethyl sulfoxide sterile-filtered (DMSO ...
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bioRxiv - Synthetic Biology 2022Quote: (5Z)-5[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4H-imidazol-4-one (DFHBI-1T) was purchased from Tocris Bio-techne ...
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bioRxiv - Neuroscience 2022Quote: ... injected with saline (control) or a range of doses (0.3, 1, 3, or 10mg/kg) of (R)-CPP (Tocris Bioscience ...
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bioRxiv - Neuroscience 2019Quote: ... cells were voltage clamped at Erev Glu (+5 mV) in the presence of 1 uM Tetrodotoxin (Tocris). For all groups ...
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bioRxiv - Developmental Biology 2021Quote: ... and 1 μM IDE-1 and 1 μM XAV939 (both Tocris). 48 hours after the onset of differentiation ...
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bioRxiv - Genomics 2021Quote: ... neurons were made quiescent for 2 hours with 100 μM D-2- amino-5-phosphonopentanoic acid (D-AP5; Tocris #0106) and 1 μM tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...