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Citations for Tocris :
251 - 291 of 291 citations for Dioctanoyl phosphatidic acid sodium salt since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Immunology 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid (DCPIB, 1540) was from Tocris. NS3728 and NBC19 were made at the University of Manchester.
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bioRxiv - Neuroscience 2020Quote: ... all electrophysiological recordings were performed in the presence of picrotoxin (100μM) and 3-((R)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP; 10μM; Tocris Bioscience), and a cut was made between CA3 and CA1 regions to prevent the propagation of epileptiform activity ...
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bioRxiv - Immunology 2024Quote: ... The FFA2R antagonist CATPB ((S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl) phenyl) butanoic acid) was from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... and 5 μM (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP, NMDA receptor antagonist, Tocris, 0173) were added to the aCSF and perfused for 3 min after which the synaptic responses of the neurons to photostimulation were measured again ...
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Neuroscience 2021Quote: ... Glutamatergic neurons were identified by their characteristic EPSC time course and by sensitivity of EPSC to application of glutamate receptor antagonist kynurenic acid (Tocris). Synaptic currents were acquired at 10 kHz using pClamp 10.2 software (Molecular Devices ...
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bioRxiv - Neuroscience 2021Quote: ... and GluN2BGC−/− mice (P40 – P60) were stereotactically injected with 50 nl of 20 mM solution of kainic acid (Tocris / Biotechne) in 0.9 % NaCl to the left CA1 area of the dorsal hippocampus (AP −1.8 mm ...
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bioRxiv - Genomics 2021Quote: ... neurons were made quiescent for 2 hours with 100 μM D-2- amino-5-phosphonopentanoic acid (D-AP5; Tocris #0106) and 1 μM tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2020Quote: ... The GAT1 blocker NO-711 [(1,2,5,6-tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride] and GAT3 blocker SNAP-5114 [1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid] were purchased from Tocris Bioscience (Minneapolis ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141], 2.5 µM DAPT [Tocris, 2634] ...
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bioRxiv - Neuroscience 2022Quote: Astrocytes grown in 6-well plates were refreshed with glial maintenance media or glial maintenance media supplemented with 100 μM L-Glutamic Acid (Tocris) for 3 h ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 μM 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531; GABAA receptor antagonist, all from Tocris). The resting membrane potential was measured after whole-cell configuration was achieved ...
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bioRxiv - Microbiology 2024Quote: ... SH- SY5Y cells were differentiated into mature neurons by the reduction of the FBS concentration in the culture medium to 3% and the addition of 100 nM retinoic acid (Tocris) for 72h ...
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bioRxiv - Neuroscience 2021Quote: ... NMDA receptor (R) dependency was tested by application of an NMDAR antagonist (APV 50 µM, DL-2-Amino-5-phosphonopentanoic acid, Tocris, Germany) in the bath solution ...
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bioRxiv - Cell Biology 2021Quote: ... B/D medium was supplemented during submerged culture with 1 nM EC23 (light-stable retinoic acid receptor agonist; Tocris, Abingdon, UK). After confluence was reached ...
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bioRxiv - Neuroscience 2022Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) (both from Tocris, Bristol, UK) to block recurrent glutamatergic signaling.
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bioRxiv - Neuroscience 2020Quote: ... to isolate inner retinal signaling (B-waves) and DL-2-Amino-4-phosphonobutyric acid (DL-AP4, 40µM, Tocris Bioscience, Bristol, U.K.) to isolate the photoreceptor component of the ERG signal (A-wave) ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141] ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 µM 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531;GABAA receptor antagonist; all from Tocris Bioscience).
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bioRxiv - Neuroscience 2022Quote: ... was inserted into the guide cannula and a Hamilton Syringe was used to administrate 1 μL of 2 mM pyridoxalphosphate-6-azophenyl-2’,4’-disulfonic acid (PPADS, Tocris, 0625), 1.5 μg/μL S961 (Phoenix Pharmaceuticals ...
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bioRxiv - Neuroscience 2023Quote: ... Mice were injected intraperitoneally (i.p.) with 5.0mg/kg synthetic kainic acid (KA) dissolved in 0.9% saline (#7065, Tocris Bioscience, Bristol, United Kingdom). At twenty-minute intervals ...
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bioRxiv - Neuroscience 2023Quote: ... 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid (DQP 1105, 10 μM dissolved in DMSO; Tocris Bioscience), or 6-Cyano-7-nitroquinoxaline-2,3-dione disodium (CNQX ...
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bioRxiv - Neuroscience 2023Quote: ... The following compounds were added to raCSF as indicated in the Results section: D-(-)-2-Amino-5-phosphonopentanoic acid (D-APV, 100 μM dissolved in H2O; Tocris Bioscience), (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine maleate (MK-801 ...
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bioRxiv - Cell Biology 2022Quote: ... The FFA2R antagonist CATPB ((S)-3-(2-(3-chlorophenyl)acetamido)-4-(4-(trifluoromethyl)-phenyl) butanoic acid) was from Tocris (Britsol, UK).
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bioRxiv - Cancer Biology 2024Quote: To induce the degradation of AID-NCL, cells were treated with 5-phenyl-indole-3-acetic acid (phenyl-auxin, 5-Ph-IAA) (Tocris, #7392). To block the interaction between APC/C and cdc20 ...
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bioRxiv - Neuroscience 2024Quote: ... cultures were maintained in neural maturation media [neural expansion media supplemented with 0.2 mM L-ascorbic acid (Tocris, 40-555-0), 20 ng/mL BDNF (R&D Systems ...
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bioRxiv - Neuroscience 2024Quote: ... Bilateral excitotoxic lesions of the dorsal striatum sub-regions (i.e. medial or lateral) were performed by injections of ibotenic acid (10mg/mL, Tocris, Bristol, UK) dissolved in a mixture of sterile NaCl (0.9% ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... Retinoic acid, BMS453 (RARβ agonist, CAS166977-43-1) and CD2665 (RARβ/γ antagonist, CAS 170355-78-9) were purchased from Tocris Biosciences (Bristol ...
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bioRxiv - Neuroscience 2021Quote: ... The bath solution usually contained 6,7-dinitroquinoxaline-2,3-dione (DNQX, 10 µM) and D- aminophosphonovaleric acid (D-APV, 50 µM) to block ionotropic glutamate receptors (Tocris, Abingdon, United Kingdom). Patch electrodes had resistances of 4-6 MΩ when filled with KMeSO4- or CMeSO4-based internal solution (same as used in vivo) ...
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bioRxiv - Neuroscience 2020Quote: ... containing 10 μM 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 50 μM D,L-2-amino-5-phosphonovaleric acid (AP5) to block glutamatergic signaling (both from Tocris, Bristol, UK). Experiments involving tetrodotoxin (TTX ...
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bioRxiv - Neuroscience 2020Quote: ... 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester (KN-62; Tocris and HelloBio); D-AP5 (HelloBio) ...
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bioRxiv - Neuroscience 2020Quote: ... co-applied with the competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid AMPA/kainate receptor antagonist CNQX (Tocris; 20 μM) (n=13) ...
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bioRxiv - Immunology 2020Quote: ... These cells were then directed to become proepicardial cells by the addition of retinoic acid and WNT CHIR 99021 followed by TGFβ inhibition (SB431542, Tocris Bioscience 1614). Finally ...
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bioRxiv - Neuroscience 2023Quote: ... and cells were centrifuged at 200 rcf for 5 min and resuspended in N2B27 with the same supplements as on day 0 except for the removal of Y27632 and addition of all-trans retinoic acid (100 nM; Tocris, 0695/50) and SAG (500 nM ...
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bioRxiv - Neuroscience 2024Quote: ... or N-methyl-D-aspartic acid (NMDA) (final concentration 100 μM; 1 µL stock solution in PBS in 1 ml media 0114; Tocris, Abingdon, UK). A DMSO-only control was conducted for comparison with PTX ...
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bioRxiv - Neuroscience 2021Quote: ... and MNI-caged-L-glutamate ((S)-α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid) were purchased from Tocris (Bristol, UK). Rhod-2 tripotassium salt was purchased from AAT Bioquest (Sunnyvale ...
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bioRxiv - Cell Biology 2024Quote: All cell lines were washed with PBS then starved of amino acids or FBS for 2 hours before treatment with the GPCR antagonists at 1 µM: CNO (Tocris/bio-techne 6329), Isoprenaline/Carvedilol (Sigma/Merck I6504 ...
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bioRxiv - Neuroscience 2020Quote: ... The bath solution for recordings contained elevated concentrations of divalent cations [4 mM Ca2+ and 4 mM Mg2+] and NMDA receptor antagonist 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) [5 mM] (Tocris biosciences, 126453-07-4). Slices were used 1.5–4.5 hours after preparation ...
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bioRxiv - Neuroscience 2021Quote: ... A glass micropipette (tip diameter ∼ 30 µm) containing a 0.5M GABA solution (γ-aminobutyric acid; 0344, Tocris; dissolved in 0.9% w/v NaCl solution) was then advanced into the brain using a zero-drift micromanipulator under stereotaxic control ...