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Citations for Tocris :
1851 - 1900 of 2017 citations for 6 Heptenoic acid 7 2 cyclopropyl 4 4 fluorophenyl 3 quinolinyl 3 5 dihydroxy calcium salt 1 1 3R 5S 6E since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2021Quote: ... SB431542 (#1614) and guanosine 5′-[β,γ-imido]triphosphate (GMPPNP, #G0635) were purchased from Tocris and Sigma-Aldrich ...
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bioRxiv - Neuroscience 2022Quote: ... for 5 min at 37°C and replating in 10μM ROCK inhibitor Y-27632 (Tocris) for 24h.
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bioRxiv - Neuroscience 2021Quote: ... Cdk-5 inhibitor (Roscovitine, 10 µM) and GSK-3β inhibitor CHIR 98014 (10 µM, Tocris) were added 30 min prior to IL-13 treatment ...
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bioRxiv - Neuroscience 2022Quote: ... The two agents used were a mixture of AMPA (5 mM) (Cat no. 0254, Tocris) and NMDA (10 mM ...
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bioRxiv - Bioengineering 2023Quote: ... or pharmacological inhibitors of focal adhesion kinase (FAK) (FAK inhibitor 14, 5 µM, Tocris, UK), Rho-associated protein kinase (ROCK ...
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bioRxiv - Neuroscience 2023Quote: ... we applied for 5 minutes the specific sodium channel blocker tetrodotoxin (TTX, 500 nM, Tocris) in combination with potassium channel blocker 4-aminopyridine (4-AP ...
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bioRxiv - Neuroscience 2021Quote: The following drugs were used: 20 µM WIN 55212-2 (WIN; Tocris Bioscience), 100 µM 2-AG (Tocris Bioscience) ...
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bioRxiv - Neuroscience 2021Quote: ... neurons were stimulated in the presence of 2 μM GSK3 inhibitor (CT99021, Tocris) and placed in fresh basal medium containing 2 μM GSK3 inhibitor for 10 min at 37°C and 5% CO2 ...
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bioRxiv - Neuroscience 2023Quote: ... either saline (0.4%) or clozapine N-oxide (CNO, TOCRIS Bioscience, 2 mg/kg) was injected i.p ...
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bioRxiv - Cancer Biology 2022Quote: ... the TGF-beta/Activin/Nodal inhibitor SB-431542 (2 μM, Cat# 1614, Tocris), CHIR99021 (1 μM ...
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bioRxiv - Cancer Biology 2023Quote: Cells were incubated for six days with Lalistat (Lalistat 2, TOCRIS, Bristol, UK) in a 6-well plate ...
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bioRxiv - Bioengineering 2024Quote: ... CDM was supplemented with 2 μM Wnt-C59 (Tocris Bioscience, cat. no. 5148). Following CDM was changed every two days ...
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bioRxiv - Neuroscience 2023Quote: ... GluN2B was inhibited by 2 µM RO 25-6981 (Tocris Bioscience, Bristol, UK) (Abrahamsson et al. ...
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bioRxiv - Neuroscience 2024Quote: ... mice were allowed to recover for 2 weeks before administration of CNO (Tocris). CNO was dissolved in drinking water ...
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bioRxiv - Biochemistry 2024Quote: ... and ligands (LXA4 and 15-oxo-LXA4-Me at 2 μM, WKYMVm (Tocris) at 5 μM) ...
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bioRxiv - Neuroscience 2021Quote: ... To interfere with group I metabotropic glutamate receptor (mGluR) signaling we used bath application of either the mGlu1 receptor antagonist YM298198 (1 μM, Tocris, Germany) or the mGluR5 receptor antagonist MPEP (10 μM ...
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bioRxiv - Neuroscience 2020Quote: ... in either plain Tyrode (stimulated condition) or Ca2+-free Tyrode containing 1mM EGTA and 1 μM TTX (#1069; Tocris Bioscience, Germany) (unstimulated condition) ...
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bioRxiv - Neuroscience 2020Quote: ... To assess the monosynaptic nature of BLA-EPSCs recordings were obtained in the presence of (in μM): 1 TTX (Tocris Bioscience), 100 4-aminopyridine (4-AP ...
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bioRxiv - Genetics 2022Quote: ... cells were seeded in a 96-well plate on a feeder layer at a low density (~ 1 cell per well) in XEN media supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris #1254) until clones appeared (approximately 5 days) ...
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bioRxiv - Neuroscience 2023Quote: ... Miniature excitatory postsynaptic currents (mEPSCs) and miniature inhibitory postsynaptic currents (mIPSCs) were recorded in the presence of 1 μM Tetrodotoxin (Tocris, 1069) at a holding voltage of -60 mV and +10mV ...
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bioRxiv - Neuroscience 2023Quote: ... Mossy fiber purity of signals was verified at the end of each recording with the application of 1 µM DCG-IV (#0975, Tocris Bioscience). All recordings with a suppression of at least 75% of the signal were used for analysis.
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bioRxiv - Genetics 2023Quote: ... and 10 µg of the Lenti guide puro/blast-gRNA plasmid using 1 mg/ml of PEI transfection reagent (Tocris, 7854). Incubation with the transfection mix was done for 5 hours at 37 °C ...
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bioRxiv - Cancer Biology 2023Quote: Cells grown in normal culture media supplemented with 10 ng/ml doxycycline for 48 hours to induce shRNA or treated with 1 μM TCE5003 (Tocris, 5099) for 22 hours ...
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bioRxiv - Neuroscience 2023Quote: ... To obtain an alternative blockade of N-type VGCCs we used N-[[4-(1,1-Dimethylethyl)phenyl]methyl-N-methyl-L-leucyl-N-(1,1-dimethylethyl)-O-phenylmethyl)-L-tyrosinamide (pd173212, purchased from TOCRIS, Bristol, UK) that was used at the final concentration of 5 µM ...
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bioRxiv - Neuroscience 2024Quote: ... To enhance their neuronal fate NSC medium was enriched by 1 µM dorsomorphin (Stemgent, USA) and 10 µM SB-431542 (Tocris, UK). The selected neurorosettes were allowed to form neurospheres in T25 flasks ...
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bioRxiv - Cell Biology 2024Quote: THP-1 cells were differentiated in complete media with phorbol 12-myristate-13-acetate (PMA; 100 nM) (cat no. 1201/1; Tocris, UK) for 72 hr ...
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bioRxiv - Neuroscience 2019Quote: DIV6–DIV8 mouse cortical neurons either immediately after transfection with HA-Nrxn1α or untransfected were treated for 48 hr (refreshed after 24 hr) with 1 μM tetrodotoxin (TTX) (Tocris, Cat #1069) or 30 μM picrotoxin (PTX ...
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bioRxiv - Neuroscience 2021Quote: ... which is a 1:1 combination of SKSRM and neuronal maintenance medium (NMM) supplemented with 10 μM SB431542 and 1 μM dorsomorphin (both from Tocris Bioscience Inc) for 10 days for neuronal induction ...
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bioRxiv - Biophysics 2022Quote: ... or αCD45 Fab (prepared as in previous work)8 was added in a 1:10 molar ratio to the desired dye - PAJF549 (Tocris Bioscience, UK) or HM-SiR (Sarafluor-650B ...
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bioRxiv - Neuroscience 2019Quote: ... The following compounds were used in pharmacological experiments: 1-Naphthyl acetyl spermine trihydrochloride (“Naspm”, 100 mM in PBS, Tocris Cat No 2766); (+)-MK 801 maleate (“MK-801” ...
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bioRxiv - Neuroscience 2019Quote: ... were measured in voltage clamp at a holding potential of −60 mV in the presence of 1 μM tetrodotoxin (Tocris, Bristol, UK) and 100 μM picrotoxin (Tocris ...
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bioRxiv - Molecular Biology 2022Quote: ... The cell lines were maintained in mTeSR1 Plus Medium (Stemcell Technologies 100-0276 and 1 µM of Rock inhibitor (RI) (Tocris 1254). Differentiation was achieved by culturing the cells for 16 days in N2B27 media ...
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bioRxiv - Neuroscience 2022Quote: ... Non-specific binding sites were blocked by incubating the cells for 30 min in freshly-prepared blocking solution (1X TTBS, 1% bovine serum albumin (Tocris Bioscience, UK) and 0.25% Triton-X100) ...
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bioRxiv - Pathology 2023Quote: ... CoCl2 (200 μmol/L) and DPD (20 μmol/L) or the HIF-1 inhibitor chetomin (Tocris, Bristol, United Kingdom, 12 nmol/L).
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bioRxiv - Neuroscience 2024Quote: ... to prevent recruitment of neuronal circuits that could lead to endogenous PACAP1-38 release (Tocris, biotechne; #Tocris 1262/50, #Tocris 0373/50, # Tocris0247/50, #Tocris 1248/50, #Tocris 1069/1).
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bioRxiv - Neuroscience 2023Quote: ... 5-HT1A-R agonist 8-OH-DPAT or antagonist NAN-190 (NAN) were from Tocris (UK). Competition was performed at concentration between 10−11 to 10−5 M ...
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Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutationbioRxiv - Pathology 2023Quote: ... cells were treated with RPMI enriched with insulin-free B27 and 5 µM IWP2 (Tocris Bioscience) for 48 hours and then the medium was replaced with RPMI enriched with insulin-free B27 ...
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bioRxiv - Neuroscience 2023Quote: ... The following peptides were delivered in 5 µL of sterile saline: GRP (295 ng, Tocris 1789), Substance P (400 ng ...
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bioRxiv - Neuroscience 2020Quote: ... Cells were inhibited by pre exposure for 2 hours with Edelfosine (10 µM) (Tocris) or U73122 (5 µM ...
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bioRxiv - Neuroscience 2020Quote: ... Cells were inhibited by pre exposure for 2 hours with Edelfosine (10 µM) (Tocris) or U73122 (5 µM ...
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bioRxiv - Cell Biology 2021Quote: ... Raptor ER-Cre mice and littermate controls were treated with 2 mg tamoxifen (Tocris) in 100 μL corn oil via gavage on 5 consecutive days ...
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bioRxiv - Biochemistry 2022Quote: ... 0.055 mM 2-mercaptoethanol and 1μg/ml Insulin) plus 1.5 μM Dorsomorphin (Tocris Bioscience) and 10 μM SB431542 (Stemgent ...
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bioRxiv - Immunology 2020Quote: ... then patterned towards midgut in RPMI+2%B27 with 3μM CHIR99021 (Wnt agonist, TOCRIS) and 500ng/ml recombinant FGF4 (R&D ...
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bioRxiv - Neuroscience 2021Quote: ... half of the neuronal cultures were treated at DIV13 with 2 μM TTX (Tocris) for 48 h.
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bioRxiv - Developmental Biology 2021Quote: ... the culture medium was changed to E6 medium supplemented with 2 μM XAV939 (Tocris Bioscience ...
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bioRxiv - Neuroscience 2021Quote: We inhibited LRRK2 kinase activity with the selective LRRK2 inhibitor MLi-2 (Tocris 5756). MLi-2 has low solubility in water ...
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bioRxiv - Genomics 2021Quote: ... followed by 2 uM of the Wnt signaling inhibitor Wnt-C59 (5148, Tocris Bioscience). Cells start to spontaneously beat between days 7-10 ...
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bioRxiv - Neuroscience 2021Quote: ... were dissolved in magnesium-free HEPES-aCSF in the presence of non-NMDA glutamate receptor blockers (CNQX, Tocris, 0190, 40 μM; Nimodipine, Tocris, 0600, 1 μM; LY-367385, Sigma, L4420, 100 μM; MPEP, Tocris, 1212, 10 μM). Type I mGluR agonist DHPG (Tocris ...
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bioRxiv - Molecular Biology 2019Quote: ... followed by incubation with 1μM of IBMX at 37 °C for 15 mins in the presence or absence of the D1R/D5R agonist fenoldopam (1 μM, #1659, Tocris Bioscience, Bristol, UK) or forskolin (5 μM ...
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bioRxiv - Neuroscience 2023Quote: ... The [11C]MeOTf was slowly bubbled into a reaction vial containing 0.2mg 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine precursor (Tocris, Bio-Techne Corp., Minneapolis, MN) and 0.3mL anhydrous MeCN (ThermoFisher Scientific ...