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1701 - 1709 of 1709 citations for 1 4 Dichloro 2 5 bis dichloromethyl benzene since 2020

• DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates

  Sascha A.L. Mueller, et al., bioRxiv - Neuroscience 2023

  Quote: ... The [11C]MeOTf was slowly bubbled into a reaction vial containing 0.2mg 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine precursor (Tocris, Bio-Techne Corp., Minneapolis, MN) and 0.3mL anhydrous MeCN (ThermoFisher Scientific ...
• SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

  Vera Stamenkovic, et al., bioRxiv - Neuroscience 2023

  Quote: ... were dissolved in HEPES-aCSF in the presence of non-NMDA glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; LY-367385, Sigma, L4420, 100 µM; MPEP, Tocris, 1212, 10 µM). Type I mGluR agonist DHPG (Tocris ...
• Development of Gemcitabine-Modified miRNA Mimics as Cancer Therapeutics for Pancreatic Ductal Adenocarcinoma

  John G. Yuen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... USA), nicotinamide (final concentration, 10 mmol/L) (MilliporeSigma, St. Louis, MO, USA), prostaglandin E2 (final concentration, 1 μmol/L) (Tocris Bioscience, Bristol, UK) B27 supplement (final concentration ...
• Microglia-astrocyte interplay mitigates Aβ toxicity in a novel human 3D neurosphere model of Alzheimer’s Disease

  Stefan Wendt, et al., bioRxiv - Neuroscience 2024

  Quote: ... hiPSCs were plated in 6-well plates in Basal Neural Maintenance media (BNMM) (Suppl. Table 1) supplemented with 10 μM SB-431542 (Tocris, Bristol, United Kingdom) and 0.5 μM LDN-193189 (Tocris ...
• Synaptic signaling networks encode experience by assuming stimulus-specific and brain-region-specific states

  Jonathan D. Lautz, et al., bioRxiv - Neuroscience 2021

  Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 μM; Nimodipine, Tocris, 0600, 1 μM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
• Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution

  Spenser S. Smith, et al., bioRxiv - Developmental Biology 2020

  Quote: ... cells were treated with 1 µM SB431542 (S4317, MilliporeSigma, Burlington, MA, USA) to inhibit TGFβR1 activity or 3µM SIS3 (5291, Tocris/R&D Systems, Minneapolis, MN, USA) to inhibit SMAD3 solubilized in 50 mM DMSO ...
• SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

  Vera Stamenkovic, et al., bioRxiv - Neuroscience 2023

  Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
• Rescue of Impaired Blood-Brain Barrier in Tuberous Sclerosis Complex Patient Derived Neurovascular Unit

  Jacquelyn A. Brown, et al., bioRxiv - Neuroscience 2023

  Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
• Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells

  Saeko Akiyama, et al., bioRxiv - Cell Biology 2023

  Quote: ... 20 μM forskolin (solvent: DMSO, 063-02193, Fujifilm Wako Pure Chemicals, Osaka, Japan) and 1 μM LDN193189 (solvent: DMSO, 6053-10, Tocris Bioscience Bristol United Kingdom), with an induction period of 10 days.