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Citations for Tocris :
1651 - 1700 of 1721 citations for 7 Bromoacetyl 6 ethyl 1 2 3 4 tetrahydro 1 1 4 4 tetramethylnaphthalene since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2024Quote: ... 2-amino-5-phosphonopentanoic acid (AP5) (cat. # 0106) and picrotoxin (cat. # 1128) were purchased from Tocris. Barium chloride (BaCl2-2H2O ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...
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bioRxiv - Genomics 2022Quote: ... Media was then changed to CM Media supplemented with 2 μM Wnt-C59 (Tocris Biosciences, Bristol, UK) for 2 days prior to switching to CM Media without any supplements ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2024Quote: ... and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist, Tocris).
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bioRxiv - Neuroscience 2021Quote: Bilateral mosaic tadpoles expressing GCaMP6s at stage 48 were immobilized in 2 mM pancuronium dibromide (Cedarlane/Tocris 0693) and embedded in 1% low melting point agarose in a petri dish filled with 0.1X MBSH ...
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bioRxiv - Neuroscience 2021Quote: ... the same routine was repeated in the presence of the glutamate transport blocker TFB-TBOA 2 μM (Tocris). For both traces the fluorescence change was calculated from the average of the baseline fluorescence intensities for each ROI as ΔF/F = (FSBFI - FSBFI(baseline)/FSBFI(baseline) ...
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bioRxiv - Cell Biology 2020Quote: ... the γ-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine1,1-dimethylethyl ester (DAPT) (Tocris) was added at a concentration of 5 μM ...
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bioRxiv - Genomics 2019Quote: ... 20ng/ml human LIF (all from WT-MRC Cambridge Stem Cell Institute) and 2 μM Gö6983 (PKCi; Tocris) on Matrigel–coated plates (Corning) ...
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bioRxiv - Neuroscience 2022Quote: Rats were bilaterally infused with either the selective α4β2 nicotinic antagonist DHβE (low dose: 15μg/.5μL/side, high dose 30μg/.5μL/side; Tocris Bioscience, Bristol, UK) the non-selective dopamine receptor antagonist Flupenthixol (15μg/.5μl/side ...
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bioRxiv - Biophysics 2022Quote: ... the 2-methylphenylureaphenylacetyl (MUPA) moiety with LDVPAAK peptide (MUPA-LDVPAAK; now commercially available, Tocris, 7020, supplementary Fig. 12) was custom synthesized by Bio-Synthesis and the amine group of its lysine side chain was reacted with the NHS group of sulfo-SMCC ...
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bioRxiv - Cell Biology 2022Quote: ... LPS was washed off and the macrophages were treated with 2 μM MK6-83 (cat no. 5547, Tocris), 20 μM MLSA-1 (cat ...
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bioRxiv - Genomics 2023Quote: ... and seeded at a seeding density of 10,000–25,000 cells/cm2 in mTeSR supplemented with 2 μM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Neuroscience 2023Quote: All recordings were done in ACSF-2 without or with 10 μM DQP 1105 (Tocris Bio-Techne, France), 10 μM DQP 1105 + 1μM Ro 25-6981 (Tocris Bio-Techne ...
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bioRxiv - Neuroscience 2023Quote: ... GRP was applied to the spinal cord to evoke Ca2+ oscillations and 2-APB (100 µM, Tocris 1224) 10 min later ...
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bioRxiv - Biophysics 2023Quote: ... whereas IS-2 sample was made up to 100 µM CTZ and 100 µM GYKI- 52466 (Tocris, 1454) prior to centrifugation (75,000 g ...
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bioRxiv - Neuroscience 2021Quote: ... and nor-Binaltorphimine dihydrochloride (norBNI, KOR antagonist, 10 mg/kg, i.p.) (CAS# 113158-34-2) were obtained from Tocris and dissolved in 0.9% sterile saline ...
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bioRxiv - Neuroscience 2019Quote: ... To block NMDA receptors we used D- (-)-2-Amino-5-phosphonopentanoic acid (D-AP5, Tocris, 10 μM final concentration). To block glycinergic inhibition ...
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bioRxiv - Neuroscience 2020Quote: ... 20 μM 6,7-dinitroquinoxaline-2,3-dione (DNQX) and 20 μM D-(-)-2-amino-5-phosphopentanoic acid (D-AP5) (Tocris Bioscience) to block glycine- ...
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bioRxiv - Biophysics 2022Quote: ... 100 μM 2-APB blocking stretch-activated inositol triphosphate receptors (InsP3Rs) on the ER/nuclear membranes (Tocris Bioscience #1224), 100 μM CK-666 (Tocris Bioscience #3950 ...
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bioRxiv - Neuroscience 2020Quote: ... were performed on mice with no knee injections 20 min before and after C21 (2 mg/kg diluted in sterile saline from a stock of 100 mM in ethanol, i.p., Tocris) injection.
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bioRxiv - Cell Biology 2021Quote: ... AKT (20 μM MK2206, Cayman Biochemicals #1032350-13-2) and myosin ATPase activity inhibitor (5 μM Blebbistatin, Tocris #1852).
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bioRxiv - Cell Biology 2021Quote: ... organoids cultured for 8 days with airway cell culture medium were followed by inclusion of CHIR99021 (2 µM, Tocris) for additional 10 days with or without DAPT (20 µM) ...
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bioRxiv - Cell Biology 2023Quote: ... 3- (4,5-dimmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays were used to estimate cell number following the manufacturer’s description (Tocris, # 5224), and absorbance was measured at 550 nm in an EnsightTM 96-well plate reader (Perkin Elmer).
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Self-organised pattern formation in the developing neural tube by a temporal relay of BMP signallingbioRxiv - Developmental Biology 2023Quote: ... cells were dissociated from the 100 mm dishes and 2.8-3M cells per well were seeded on the prepared 2-well dishes in N2B27 medium with 10ng/ml bFGF + 10µM Y-27632 ROCK inhibitor (Tocris) media for 3h ...
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bioRxiv - Biochemistry 2024Quote: ... with or without the gamma-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester (DAPT; Tocris, 2634) at a final concentration of 10 µM ...
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bioRxiv - Cell Biology 2024Quote: ... supplemented with 5.5 mM glucose prior to sequential 30 min incubations of KRBH containing low (2 mM) and high (20 mM) glucose with or without 2.5 nM GIP (Tocris Bioscience ...
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bioRxiv - Neuroscience 2020Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
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bioRxiv - Neuroscience 2021Quote: ... Four of the rats were also infused with 2 μL of either physiological saline or 5 μg/μL yohimbine (Tocris) with a flow rate of 0.5 μL/min as previously reported (Caetano et al. ...
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bioRxiv - Cell Biology 2019Quote: Human PSC were grown for 5 days in E8 media(Chen et al., 2011) without FGF-2 and TGF-b but supplemented with 10μM CHIR99021 (Tocris, 4423). Loss of pluripotency was confirmed by RT-qPCR panel of self-renewal ...
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bioRxiv - Genomics 2020Quote: ... The involvement of the TLR1/2 in signal transduction was tested using CU-CPT22 at 10 µM (Tocris Bioscience, UK). The used concentrations of inhibitors were selected based on recommendations provided by the manufacturers ...
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bioRxiv - Neuroscience 2020Quote: ... and the Mai Tai eHP was tuned to 725nm for photoactivation of recirculated caged MNI-L-glutamate (2 mM, Tocris)57,58 ...
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bioRxiv - Neuroscience 2020Quote: ... or by either bath application or using a custom-made perfusion system (for imaging cells on 12-mm coverslips): 2-AG (Tocris), AEA (Cayman) ...
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bioRxiv - Neuroscience 2020Quote: ... QX-314 (Cat No. 1014); and D-2-amino-5-phosphonovalerate (D-AP5; Cat No. 0106) were purchased from Tocris.
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bioRxiv - Neuroscience 2021Quote: Potassium currents were isolated pharmacologically during whole-cell voltage-clamp recordings by blocking fast sodium and calcium channels as well as ionotropic receptors for GABA and glutamate (2 µM tetrodotoxin (TTX, Tocris), 300 µM NiCl2 ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down ScalingbioRxiv - Neuroscience 2021Quote: ... 6 hrs (Figure 6 – figure supplement 2) or 24 hrs after transfection (the remaining experiments) neurons were treated with tetrodotoxin (TTX, 5 µM, Tocris) for ∼16 hours ...
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bioRxiv - Cell Biology 2021Quote: ... and seeded at a seeding density of 10000-25000 cells/cm2 in mTeSR supplemented with 2 µM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Cancer Biology 2021Quote: ... and single-cell suspensions were re-plated in mTeSR1 supplemented with 2 µM ROCK inhibitor (Y-27632 Dihydrochloride Tocris #1254). Transgenic WT29 iPSCs were generated by transfecting PiggyBac expression vector and pBase (Villegas et al ...
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bioRxiv - Neuroscience 2020Quote: ... During BQA experiments the ACSF solution contained the following substances: 10 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-AP5) (Tocris), 10 μM 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (NBQX ...
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bioRxiv - Cell Biology 2022Quote: Compounds which were considered a hit after library screening were purchased from the following commercial suppliers: 2-TEDC (Tocris Bioscience), Anethole-trithione (ATT ...
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bioRxiv - Pathology 2022Quote: About 0.1 to 0.2 MOI (Multiplicity of Infection) equivalent of VSV-G and pseudotype SARS-CoV-2 spike virus particles were treated with recombinant LL37 (Tocris) and niacinamide (vitamin B3 ...
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bioRxiv - Cell Biology 2022Quote: ... resuspended in DMEM-1%BSA and incubated in suspension for 30 min at 37°C in 10% CO2 and 2 μg/ml CT04 (#CT04-A, Cytoskeleton or 10 μM EHT1864 (#3872, Tocris). The vehicle control included the corresponding dilution of DMSO as needed ...
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bioRxiv - Microbiology 2024Quote: ... the cells were hybridized with V-EV71-C1 probe (Biotechne) at 40°C for 2 hours and then the signals were revealed using TSA Vivid 570 kit (Tocris). The slides were then incubated with blocking buffer and incubated with MAB979 (1:100 ...
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bioRxiv - Neuroscience 2024Quote: ... another group of animals received an ip injection of WIN55,212-2 (0.5 mg/kg) along with CB1 receptor antagonist SR141716A (0.5 mg/kg, ip) (Tocris Bioscience, Bristol, UK). Rats were randomly selected for each group ...