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Citations for Tocris :
1501 - 1550 of 1578 citations for 5 Chloro 1 benzothiophen 2 yl methanol since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2022Quote: ... injected with saline (control) or a range of doses (0.3, 1, 3, or 10mg/kg) of (R)-CPP (Tocris Bioscience ...
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bioRxiv - Neuroscience 2024Quote: ... and incubated in blocking solution made of 1xPBS + 0.03% Triton + 1% Bovine Serum Albumin (BSA; Bio-techne Tocris 5217) for 1 hour ...
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bioRxiv - Neuroscience 2024Quote: ... PV cells and PYRs were voltage clamped at −70 mV in the presence of tetrodotoxin (TTX, 1 μM, Tocris) and picrotoxin (PTX ...
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bioRxiv - Neuroscience 2024Quote: ... Amyloid was stained with methoxy-X04 overnight (1:500 from in 5mM in distilled H2O, Cat # 4920, Tocris Bioscience) (fig ...
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bioRxiv - Microbiology 2024Quote: ... 1 mL culture was incubated with HADA at a final concentration of 10 µM (λem ≈ 450 nm, Tocris Bioscience) 19 for 10 min and washed 3X with anaerobic PBS ...
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bioRxiv - Neuroscience 2021Quote: ... an agonist of group II metabotropic glutamate receptors (mGluR2/3) that reduces release probability in mossy fiber terminals (1 μM, Tocris)(Kamiya et al. ...
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bioRxiv - Evolutionary Biology 2021Quote: ... Spontaneous excitatory postsynaptic currents (sEPSCs) were recorded at Vh=-70 mV 1 µM of SR95531 hydrobromide (Tocris, Cat no. 1262) was bath applied to block inhibitory neurotransmission ...
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bioRxiv - Neuroscience 2020Quote: Current-clamp recordings were performed using an BVC-700A amplifier (Dagan, Minneapolis, USA) with standard ACSF solution at 34°C containing the GABAB-receptor blocker CGP55845 (1 µM, Tocris). Recording pipettes with a resistance of 3-5 MΩ were pulled with a DMZ universal electrode puller (Zeitz-Instruments Vertriebs-GmbH ...
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bioRxiv - Neuroscience 2020Quote: ... iPSCs were dissociated and 9,000 cells were seeded into each well of a U-shape 96-well plates in EB Formation Medium (Basal Medium 1 with Cerebral Organoid Supplement A) and 50 mM Y27632 (Tocris). The medium was changed every second day without Y27632 ...
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bioRxiv - Neuroscience 2020Quote: ... animals were intraperitoneal (i.p.) injected (0.1 ml/ 10 g) 1 hour prior to baseline freezing assessment with norbinalthorphimine (norBNI, Tocris Cat.# 0347) diluted in sterile saline (1 mg/ ml ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... Cat. # 5274, purity ≥ 98%) and TFM-4AS-1 (CAS # 188589-61-9, Cat. # 3813, purity ≥ 98%) were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... Kinin receptors involvement in NO production by the tested peptides was assessed by selective antagonism of B1 and B2 receptors with Lys-(des-Arg9-Leu8-BK-(1-9) (B1RB) and HOE-140 (Tocris) (B2RB) ...
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bioRxiv - Pathology 2022Quote: ... rinsed in 1xPBS and treated with Sudan Black (0.3% in 70% ethanol) before being stained with a DAPI (30 nM, 10min) or Methoxy-XO4 (MxO4) solution (1/500, 30 min, Tocris). To increase the detectability of the AT8 staining ...
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bioRxiv - Cell Biology 2022Quote: ... Supernatants were mixed with cathepsin-specific fluorescent substrate and optionally with 10 µM L 006235 or 1 µM pepstatin A (Tocris) and incubated for 1 h at 37 °C ...
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bioRxiv - Genetics 2022Quote: ... All supernatant was removed and each viral pellet was resuspended with 300 µl of 1% Bovine Serum Albumin (Tocris Bioscience) in Phosphate Buffer Solution (Sigma) ...
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bioRxiv - Cell Biology 2020Quote: ... definitive endoderm cells were generated from hESCs (∼90% confluence) by the combination of 1-2µM CHIR-99021 (Tocris, 4423-10MG) [9] and 100ng/ml ActivinA (R&D Systems ...
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bioRxiv - Molecular Biology 2020Quote: ... kin28as strains and their controls were then grown to an OD600 of 0.8 and treated with 6 μM of 1-Naphthyl PP1 (NAPP1; Tocris Bioscience) for 15 min ...
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bioRxiv - Neuroscience 2021Quote: ... were recorded from hippocampal GAD67-GFP negative excitatory and GAD67-GFP positive inhibitory neurons incubated in the presence of tetrodotoxin (TTX, 1 μM; Tocris) to block spontaneous action potentials ...
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bioRxiv - Developmental Biology 2021Quote: ... and then anterior primitive streak was briefly washed (with DMEM/F12) and then treated with CDM2 basal media supplemented with A8301 (1 μM; Tocris), LDN193189 (250 nM ...
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bioRxiv - Developmental Biology 2021Quote: ... and then definitive ectoderm was briefly washed (with DMEM/F12) and then treated with CDM2 basal media supplemented with A8301 (1 μM; Tocris), LDN193189 (100 nM ...
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bioRxiv - Developmental Biology 2021Quote: ESCs were then differentiated into definitive ectoderm through the addition of CDM2 basal medium supplemented with A8301 (1 μM; Tocris), LDN193189 (100 nM ...
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bioRxiv - Developmental Biology 2021Quote: ... Mesoderm was briefly washed (with DMEM/F12) and then treated with CDM2 basal media supplemented with CDM2 base media supplemented with A8301 (1 μM; Tocris), LDN193189 (250 nM ...
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bioRxiv - Microbiology 2020Quote: ... The concentrations of hydrocortisone for both BEGM and ALI were increased to 0.48 μg/ml and BEGM was further supplemented with the inhibitors 1 μmol/L A83-01 (Tocris, USA), 3 μmol/L isoproterenol (Abcam ...
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bioRxiv - Neuroscience 2022Quote: ... Monosynaptic natures of excitatory transmission evoked in the LA- to-aBA pathway was tested by bath application of tetrodotoxin (TTX, 1 μM, Tocris) and subsequently 4-AP (400 μM) ...
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bioRxiv - Neuroscience 2023Quote: ... HS-AFM observations of GluA2-γ2 in the desensitized state were performed on mica in buffer A with 0.1% O310F and 1 mM L-quisqualate (Quis, #0188, Tocris, UK). For HS-AFM observations of the GluA2-γ2 and NP1 complex ...
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bioRxiv - Neuroscience 2022Quote: ... All supernatant was removed and each viral pellet was resuspended with 300 µl of 1% bovine serum albumin (Tocris Bioscience) in phosphate buffer solution (Sigma) ...
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bioRxiv - Neuroscience 2022Quote: Primary microglia cells from C57Bl/6 J mice cultured in presence of CSF-1 were treated with Formoterol (10 ng/ml, cat # 1448, Tocris) or vehicle for 1 hour ...
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bioRxiv - Cell Biology 2023Quote: ... The indicated drugs were directly added in the culture medium: torin-1 (10 μM) (4247/10, R&D and Tocris), Rotenone (500 nM ...
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bioRxiv - Cancer Biology 2023Quote: ... also known as H-1152 dihydrochloride (CAS 451462-58-1), was Santa Cruz Biotechnology (Dallas, TX). Fasudil (Cat. # 0541/10) and hydroxyfasudil hydrochloride (Cat. #2415) were purchased from Tocris Bioscience (Bristol ...
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bioRxiv - Neuroscience 2023Quote: ... and 10 μM 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531; GABAA receptor antagonist, all from Tocris). The resting membrane potential was measured after whole-cell configuration was achieved ...
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bioRxiv - Cancer Biology 2024Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Neuroscience 2024Quote: ... The synaptic blockers NBQX (#1044) and APV (#0106/1), and the sodium channels blocker tetrodotoxin (TTX, #1078) were obtained from Tocris, Bristol ...
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bioRxiv - Neuroscience 2024Quote: ... Oxotremorine (10 µM), Riluzole hydrochloride (100 µM), Strychnine (10 µM), Tetrodotoxin (TTX, 1 μM) and ZD7288 (50 µM) were obtained from Tocris. Suramin (100 µM ...
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bioRxiv - Neuroscience 2024Quote: ... were first derived from iPSCs as previously described13: iPSC colonies were grown in N2B27 media supplemented with 1 µM Dorsomorphin (Tocris), 10 µM SB-431542 (Generon) ...
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bioRxiv - Neuroscience 2024Quote: ... slices from both hippocampi were washed two times with cold External solution and incubated on ice for 30 min with 1 mg/ml Sulfo-NHS-LC-biotin (Pierce and Tocris) in External solution and slowly rocked ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... Human total eIF2α Antibody (#AF3997-SP) and human TIMP-1 antibody (#AF970-SP) were purchased from Tocris (Biotechne, United Kingdom). PNGaseF (V4831 ...
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bioRxiv - Biochemistry 2024Quote: ... A549 RIG-I−/− ACE2+ cells (80-90% confluent in 6-well plates) were transduced by adding 10 µg ml−1 Polybrene (Tocris) and recombinant lentivirus to a multiplicity of infection (MOI ...
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bioRxiv - Cancer Biology 2024Quote: ... Recipient cells were infected overnight with 1/10 of viral concentrate in media containing 8ug/mL polybrene (Tocris, 7711/10). 24-48h later ...
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bioRxiv - Cell Biology 2024Quote: ... coated 6-well plates with 1-1.5 million cells per well in E8 with 10 μM ROCK inhibitor Y-27632 (Tocris 1254). At day 1 of differentiation medium was exchanged to induction medium (IM ...
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bioRxiv - Neuroscience 2021Quote: ... To interfere with group I metabotropic glutamate receptor (mGluR) signaling we used bath application of either the mGlu1 receptor antagonist YM298198 (1 μM, Tocris, Germany) or the mGluR5 receptor antagonist MPEP (10 μM ...
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bioRxiv - Neuroscience 2020Quote: ... in either plain Tyrode (stimulated condition) or Ca2+-free Tyrode containing 1mM EGTA and 1 μM TTX (#1069; Tocris Bioscience, Germany) (unstimulated condition) ...
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bioRxiv - Cell Biology 2021Quote: ... B/D medium was supplemented during submerged culture with 1 nM EC23 (light-stable retinoic acid receptor agonist; Tocris, Abingdon, UK). After confluence was reached ...
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bioRxiv - Cell Biology 2021Quote: Receptors were stimulated as follows: human Angiotensin 1 receptor (AT1R) with Angiotensin II (AngII; Tocris 4474-91-3, in measuring buffer), human β2 adrenergic receptor (β2ADR ...
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bioRxiv - Neuroscience 2020Quote: ... To assess the monosynaptic nature of BLA-EPSCs recordings were obtained in the presence of (in μM): 1 TTX (Tocris Bioscience), 100 4-aminopyridine (4-AP ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2023Quote: ... Mossy fiber purity of signals was verified at the end of each recording with the application of 1 µM DCG-IV (#0975, Tocris Bioscience). All recordings with a suppression of at least 75% of the signal were used for analysis.
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bioRxiv - Neuroscience 2023Quote: ... and 10 µM 6-imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide (SR95531;GABAA receptor antagonist; all from Tocris Bioscience).
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bioRxiv - Genetics 2023Quote: ... and 10 µg of the Lenti guide puro/blast-gRNA plasmid using 1 mg/ml of PEI transfection reagent (Tocris, 7854). Incubation with the transfection mix was done for 5 hours at 37 °C ...
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bioRxiv - Neuroscience 2023Quote: ... maneuvered adjacent to the capillary under study and pressurized injections (200–300 ms, 7 ± 1 PSI) of 100 nM T-peptide (Tocris, USA) with tetramethylrhodamine isothiocyanate (TRITC ...
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bioRxiv - Neuroscience 2024Quote: ... To enhance their neuronal fate NSC medium was enriched by 1 µM dorsomorphin (Stemgent, USA) and 10 µM SB-431542 (Tocris, UK). The selected neurorosettes were allowed to form neurospheres in T25 flasks ...