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Citations for Tocris :
1301 - 1350 of 1426 citations for 2 Amino 6 chloro 9 3 5 di O p toluoyl beta D 2 deoxyribofurnanosyl purine since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Developmental Biology 2021Quote: ... medium was replaced with BPEL containing 5 μmol/L XAV939 (Tocris Bioscience, #3748/10). For SANCM differentiation ...
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bioRxiv - Neuroscience 2021Quote: ... saline or CNO (5 mg/kg, Clozapine N-oxide dihydrochloride, Tocris, Cat. No. 6329) was injected intraperitoneally (i.p. ...
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bioRxiv - Physiology 2023Quote: ... saturated with 95% O2 and 5% CO2 with the ectonuclease inhibitor ARL67156 (100 μM) (Tocris) for 20 min ...
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bioRxiv - Neuroscience 2023Quote: ... Cells were treated for 24 hours with 5 uM araC (Tocris 45-205-0) and media was replaced on day 3 with fresh Neuron Differentiation Media without ROCK inhibitor or araC ...
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bioRxiv - Developmental Biology 2023Quote: ... culture medium was changed to MCDB131 base medium supplemented with 5 μM CHIR99021 (Tocris) and 100 ng/ml Activin A (R&D System ...
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bioRxiv - Neuroscience 2023Quote: ... (-)-quinpirole HCl (QUIN; 0.05 mg/kg, 1 mg/kg or 5 mg/kg; Tocris), raclopride HCl (RACLO ...
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bioRxiv - Cell Biology 2024Quote: ... Trp53 loss was selected by supplementing media with 5 μM Nutlin-3a (Tocris, 6075). Rb1 loss was selected for by supplementing media with 2.5 μM Palbociclib (Tocris ...
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
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bioRxiv - Bioengineering 2023Quote: ... The supernatant was aspirated and the pellet re-suspended in fresh E8 medium supplemented with 10 µM ROCK inhibitor (Tocris R&D Systems). Re-suspended cells were seeded at a density between 7,500 – 12,500 cells / cm2 on fresh Matrigel-coated plates (Day – 3) ...
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bioRxiv - Neuroscience 2020Quote: ... the GABAA channel blocker Picrotoxin (50 µM) or the GABAB antagonist CGP-54626 (3 µM) (Tocris Bioscience, Minneapolis, MN) was bath applied 80 min prior to HFS ...
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bioRxiv - Developmental Biology 2020Quote: ... day 3 NMP-like cell cultures were treated with Accutase and replated at a density of 63,000 cells//cm2 in N2B27 supplemented with CHIR99021 (3 µM, Tocris), FGF2 (100 ng/ml ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... N,N’-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochloride (IT1t) was purchased from Tocris (United Kingdom). Bovine serum albumin ...
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Sexual dimorphism of insular cortex function in persistent alcohol drinking despite aversion in micebioRxiv - Neuroscience 2023Quote: ... The causal role of aIC or pIC glutamatergic neurons on drinking was tested after injection of CNO (i.p. 3 mg/kg in NaCl, Tocris) or vehicle 30 minutes before the last session of binge (day 18) ...
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bioRxiv - Neuroscience 2022Quote: ... injected with saline (control) or a range of doses (0.3, 1, 3, or 10mg/kg) of (R)-CPP (Tocris Bioscience ...
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bioRxiv - Immunology 2024Quote: ... we administered 3 doses (100 uL) of either vehicle control or 50 ug of the CCR3 antagonist (SB328437, Tocris) via intraperitoneal injection before TAC and during the first week of recovery ...
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bioRxiv - Neuroscience 2020Quote: ... the N3 media was further supplemented with two factors: SB-431542 (5 µM, Tocris, 1614) and LDN-193189 (100 nM ...
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bioRxiv - Immunology 2022Quote: ... or an inhibitor of CD73 inhibitor (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) (0.5 mg/mouse ...
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bioRxiv - Neuroscience 2021Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247 ...
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bioRxiv - Cell Biology 2021Quote: ... SB431542 (#1614) and guanosine 5′-[β,γ-imido]triphosphate (GMPPNP, #G0635) were purchased from Tocris and Sigma-Aldrich ...
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bioRxiv - Neuroscience 2022Quote: ... for 5 min at 37°C and replating in 10μM ROCK inhibitor Y-27632 (Tocris) for 24h.
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bioRxiv - Neuroscience 2021Quote: ... Cdk-5 inhibitor (Roscovitine, 10 µM) and GSK-3β inhibitor CHIR 98014 (10 µM, Tocris) were added 30 min prior to IL-13 treatment ...
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bioRxiv - Neuroscience 2023Quote: ... and ASM concentration was kept constant at 10 μM: Valproic acid (Tocris, #1069-66-5), Levetiracetam (Tocris ...
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bioRxiv - Neuroscience 2022Quote: ... The two agents used were a mixture of AMPA (5 mM) (Cat no. 0254, Tocris) and NMDA (10 mM ...
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bioRxiv - Neuroscience 2023Quote: ... we applied for 5 minutes the specific sodium channel blocker tetrodotoxin (TTX, 500 nM, Tocris) in combination with potassium channel blocker 4-aminopyridine (4-AP ...
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bioRxiv - Bioengineering 2023Quote: ... or pharmacological inhibitors of focal adhesion kinase (FAK) (FAK inhibitor 14, 5 µM, Tocris, UK), Rho-associated protein kinase (ROCK ...
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bioRxiv - Systems Biology 2023Quote: ... Cells were assayed by flow cytometry after 5 days of 1 µg/mL doxycycline (Tocris) treatment for repressors and 2 days of doxycycline for activators ...
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bioRxiv - Cell Biology 2024Quote: ... then blocked in Tween 0.1% Tris-buffered saline containing 5% bovine serum albumin (Tocris 5217) for at least 1h at room temperature and subsequently incubated overnight at 4°C with primary antibodies ...
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bioRxiv - Neuroscience 2021Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 μM; Nimodipine, Tocris, 0600, 1 μM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
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bioRxiv - Developmental Biology 2020Quote: ... cells were treated with 1 µM SB431542 (S4317, MilliporeSigma, Burlington, MA, USA) to inhibit TGFβR1 activity or 3µM SIS3 (5291, Tocris/R&D Systems, Minneapolis, MN, USA) to inhibit SMAD3 solubilized in 50 mM DMSO ...
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bioRxiv - Neuroscience 2023Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
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bioRxiv - Neuroscience 2021Quote: ... an agonist of group II metabotropic glutamate receptors (mGluR2/3) that reduces release probability in mossy fiber terminals (1 μM, Tocris)(Kamiya et al. ...
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bioRxiv - Neuroscience 2021Quote: ... synaptic GABA currents were recorded in perfusing aCSF containing the glutamate receptor antagonist kynurenic acid (3 mM, Tocris, Ellisville, MO). Recorded neurons were initially held at −70 mV for interneurons and −60 mV for GCs and SGCs and the response to 500 milli-second positive and negative current injections were examined to determine active and passive characteristics ...
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bioRxiv - Neuroscience 2020Quote: ... 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Neuroscience 2021Quote: ... Hox propagation was initiated by activation of Wnt signaling using NMP media comprised of E6 medium supplemented with 200 ng/mL FGF8b and 3 μM CHIR99021 (Tocris). This constitutes the “Hox timepoint” of 0hrs ...
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... 0.3 or 1 mg/kg of the mGlu2/3 receptor agonist LY379268 (Cat No.: 2453, Batch No.: 9B/232416, CAS No.: 191471-52-0, Tocris Bioscience ...
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bioRxiv - Cell Biology 2023Quote: iPSCs were first differentiated into iAT2s and passaged as above in 3D cultures in iAT2 medium (CK+DCI) supplemented for the first 3 days after passaging with 10 uM Y-27632 (Tocris). To generate iAT1s ...
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bioRxiv - Bioengineering 2023Quote: ... The media were changed at day 3 to remove the ROCK inhibitor and to add 10 µM DAPT (Tocris Bioscience), which remained until day 7 ...
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bioRxiv - Neuroscience 2022Quote: ... 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolol[1,5-a]pyrimidin-3-yl]phenol (PHTPP, 10 μM dissolved in 10% DMSO, TOCRIS, Minneapolis, MN), microinjected bilaterally into the CeA (0.5 μL over one minute with a one-minute wait post-infusion ...
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bioRxiv - Neuroscience 2023Quote: ... Extracellular action potentials were recorded in 3 independent cultures for either genotype in the presence of 50nM nifedipine (Tocris Bioscience) or vehicle using the MaestroPro (Axion Biosystems ...
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bioRxiv - Molecular Biology 2024Quote: ... AID depletion was triggered using 500 mM of Indole-3-Acetic Acid sodium salt (IAA, auxin analog) (Tocris Bioscience 7932) final ...
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bioRxiv - Microbiology 2024Quote: ... SH- SY5Y cells were differentiated into mature neurons by the reduction of the FBS concentration in the culture medium to 3% and the addition of 100 nM retinoic acid (Tocris) for 72h ...
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bioRxiv - Developmental Biology 2024Quote: Incretin mimetic drug treatments were performed by supplementing unmodified Arc-3 medium with Metformin hydrochloride at 10 µM (Tocris, 2864), Exendin-4 at 10 nM (Tocris ...
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bioRxiv - Immunology 2022Quote: ... or a CD73 inhibitor (0–1 μM) (adenosine 5’-(α, β-methylene) diphosphate (AMP-CP; Tocris) plus ATP (100 μM ...
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bioRxiv - Neuroscience 2020Quote: ... Membranes were blocked for 1 hour at RT on a shaker in 5% BSA (Tocris, 5217) with 0.1% Tween-20 (Bio-Rad ...
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bioRxiv - Neuroscience 2023Quote: ... 5-HT1A-R agonist 8-OH-DPAT or antagonist NAN-190 (NAN) were from Tocris (UK). Competition was performed at concentration between 10−11 to 10−5 M ...
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Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutationbioRxiv - Pathology 2023Quote: ... cells were treated with RPMI enriched with insulin-free B27 and 5 µM IWP2 (Tocris Bioscience) for 48 hours and then the medium was replaced with RPMI enriched with insulin-free B27 ...
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bioRxiv - Neuroscience 2023Quote: ... The following peptides were delivered in 5 µL of sterile saline: GRP (295 ng, Tocris 1789), Substance P (400 ng ...
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bioRxiv - Neuroscience 2024Quote: ... All experiments were performed in the presence of SR95531 (5 mM, Tocris Bio-Techne, Minneapolis, MN) and CGP55845 (2.5 mM Tocris ...
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bioRxiv - Cell Biology 2020Quote: ... and diabetic NOD mice (14-26 weeks; n=3) were intra-peritoneally injected with 50mg/kg of Chloroquine diphosphate (Tocris #4109). Two hours post injection ...
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bioRxiv - Cell Biology 2021Quote: Receptors were stimulated as follows: human Angiotensin 1 receptor (AT1R) with Angiotensin II (AngII; Tocris 4474-91-3, in measuring buffer), human β2 adrenergic receptor (β2ADR ...