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Citations for Tocris :
1051 - 1100 of 1199 citations for 6 Bromo 2 trifluoromethyl 3H imidazo 4 5 b pyridine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cancer Biology 2022Quote: ... 2% Sodium deoxycholate and 0.2% SDS including protease inhibitors (Aprotinin (TOCRIS Bioscience Cat. no. 4139/10) Leupeptin (Fisher Scientific ...
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bioRxiv - Genomics 2019Quote: ... the previously described medium was replaced with heart medium containing 2 μM Wnt-C59 (Tocris, 5148). On days 5 ...
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bioRxiv - Neuroscience 2020Quote: NNC-711 (1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride) from Tocris
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bioRxiv - Developmental Biology 2021Quote: ... Lin- c-Kit+ cells were sorted into 2%FCS-PBS with 100µM IWR-1 (Tocris, 3532) or control vehicle ...
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bioRxiv - Molecular Biology 2021Quote: Cells were treated for 2 hrs with vehicle (DMSO) or with 250 nM Torin1 (Tocris Biosciences), or for 1 hr with 50 μM Ly29004 (Tocris Biosciences ...
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bioRxiv - Neuroscience 2022Quote: ... we slowly infused 200 nl of the GABAA receptor agonist muscimol (Tocris; 2 μM in saline) into the target area using a micro-syringe pump (KD Scientific ...
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bioRxiv - Cell Biology 2024Quote: ... the WNT signaling inhibitor IWP-2 (2μM in DMSO, day 21-42, Tocris Bioscience, Bristol, UK), the hedgehog inhibitor cyclopamine (10μM in DMSO ...
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bioRxiv - Developmental Biology 2024Quote: ... Cells were treated as control or with 2 µM DDR1 inhibitor DDR1-in-1 (Tocris 5077) or 5 µM RUNX1 inhibitor AI-10-104 (Aobious AOB17076) ...
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bioRxiv - Neuroscience 2022Quote: The β3AR-selective antagonist SR59230A (2 mg/kg/day or 10 mg/kg/day; Tocris Bioscience) or vehicle (2:3 ratio of DMSO:0.9% saline ...
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bioRxiv - Neuroscience 2023Quote: ... followed by seven days medium d3–9 (Medium d1-2 with 3 µM CHIR99021 [Tocris, 4423]), one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich ...
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bioRxiv - Biochemistry 2023Quote: ... Cannabinoid ligands (anandamide [AEA], 2-arachydonyl-glycerol [2AG], SR144528, HU210, HU308, cannabinol) were obtained from Tocris Bioscience and dissolved in DMSO to a storage concentration of 10 mM ...
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bioRxiv - Developmental Biology 2023Quote: ... at a density of 2 × 103 cells/cm2 with 10µM ROCK inhibitor (Y-27632; Tocris, 1254) added in culture medium for 1 day after hESCs passaging ...
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bioRxiv - Neuroscience 2022Quote: ... 12-well plates at 3-4 × 105 cells/well in mTeSR1 with 10 µM rho-kinase inhibitor (Y-27632; Tocris, 1254). Medium without the inhibitor was replaced daily until the cells reach 80-100% confluency ...
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bioRxiv - Neuroscience 2021Quote: ... Alexa-fluorophore conjugated secondary antibodies were added in blocking solution for 1 hour at 4°C followed by treatment with Methoxy-X04 (Tocris, 4920) for 15 minutes at room temperature to label amyloid-beta plaques ...
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bioRxiv - Neuroscience 2020Quote: ... ACSF of similar composition to the normal ACSF but with increased concentration (4 mM) of MgCl2 and CaCl2 and supplemented with 100μM MNI-caged glutamate (Tocris Bioscience, UK) for glutamate uncaging experiments ...
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bioRxiv - Neuroscience 2022Quote: ... where they were immobilized under a nylon mesh (Smart Ephys, SHD-26GH/10) and paralyzed by injecting 0.5 nL of bungarotoxin at 0.5 mM (Tocris, #110.32-79-4) in the trunk musculature ...
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bioRxiv - Biochemistry 2022Quote: ... Positive clones were analyzed by Sanger sequencing with primers #3 and #4 (Integrated DNA Technologies, Supplementary Table S5) and degradation upon dTAG-13 (Tocris, 6605) treatment was confirmed by Western Blot by a-Chaf1a antibody (65) ...
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bioRxiv - Neuroscience 2023Quote: ... the α7 nAChR specific agonist PNU 282987 (1.6 μg total dose; 0.2 μL volume of 4 μg/μL per side; PNU 282987, Tocris, Ellisville, MO, USA), or vehicle (artificial cerebrospinal fluid [aCSF] or 50/50% aCSF/dimethylsulfoxide [DMSO] ...
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bioRxiv - Neuroscience 2023Quote: ... Firing rates of individual channels were compared before and after treatment with potassium channel blocker 4-AP (50 μM; Tocris, 0940), sodium channel blocker TTX (1 μM ...
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bioRxiv - Neuroscience 2024Quote: ... The cell suspension was then centrifuged at 1,200 rpm for 4 minutes and resuspended in mTeSR medium supplemented with 10 μM ROCK inhibitor Y-27632 (Tocris Cat # 1254) at a concentration of 10,000 cells per 100 µL or 1 million cells per 10 mL ...
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bioRxiv - Cell Biology 2020Quote: ... 0.5 mL fresh RPMI 1640 containing B-27 supplement minus insulin was added to 0.5 mL conditioned (old) medium and added to cells along with 5 µM IWP2 (Tocris). Medium was aspirated at Day 5 and replenished with fresh RPMI 1640 containing B-27 supplement minus insulin ...
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bioRxiv - Cell Biology 2020Quote: ... Electroporated cells were seeded in fresh E8 media containing 5 μM Y-27632 dihydrochloride (a selective ROCK inhibitor, Tocris) and allowed to recover for 48 hours before antibiotic selection.
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bioRxiv - Neuroscience 2021Quote: ... All neurons were recorded in control conditions and after >5 min of bath application of 1 µM DHβE (Tocris).
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bioRxiv - Neuroscience 2019Quote: Mice received an IP injection of vehicle or CNO (5 mg/kg; Tocris or National Institute of Mental Health) or vehicle (1% DMSO in saline) ...
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bioRxiv - Genetics 2021Quote: ... Cells were then incubated in RPMI/B27 (-Insulin) for 24 hours before changing media to 5 μM IWP2 (Tocris) in RPMI/B27(-Insulin) ...
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bioRxiv - Molecular Biology 2021Quote: ... Calu-3 cells were preincubated for 1 h with medium (50 μl/well) containing either increasing concentrations of Camostat (0.5, 5 or 50 μM; Tocris) or dimethyl sulfoxide (solvent control ...
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bioRxiv - Neuroscience 2023Quote: ... 5 mM QX314 was added into the intracellular pipette solution while GABAA receptor antagonist picrotoxin (PTX, 50 μM, Tocris), GABAB receptor antagonist CGP55845 (3 μM ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... the α4-selective nAChR antagonist dihydro-β-erythroidine hydrobromide (DHβE; 5 mg/kg in sterile saline; Tocris, Bristol, UK), or the α7-selective nAChR antagonist methyllycaconitine citrate (MLA ...
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bioRxiv - Neuroscience 2024Quote: ... All mice were given a 250μl subcutaneous injection of bromocriptine (5mg/kg, 5% ethanol/saline; Tocris Bioscience Cat#0427) prior to being mated ...
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bioRxiv - Neuroscience 2024Quote: ... Immunoblot was obtained by first blocking membranes for 1 h at room temperature with a solution of 0.1% Tween 20 and 5% Bovine Serum Albumin (BSA) (#5217, Tocris) in 1× PBS (pH 7.4 ...
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bioRxiv - Cancer Biology 2023Quote: ... Organoids are pelleted and gently resuspended in BTOM-ER containing 5% Matrigel and ROCK-inhibitor (10 μM Y267632, Tocris), and then plated on top of a solidified Matrigel-coated well ...
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bioRxiv - Cell Biology 2023Quote: For inhibition of P2X4R cells were pre-incubated for 30 min with 10 μM of 5-BDBD (Tocris Bioscience). Blockage of αvβ3/αvβ5 integrins was achieved by the pre-incubation with 10 μM of cilengitide for 2 hours (Sigma-Aldrich).
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bioRxiv - Bioengineering 2024Quote: ... cells were either directly imaged or washed 1x and incubated for 5 min with Hoechst 33342 (Tocris, 5117/50) to a final concentration 1 ng/µL prior to imaging ...
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bioRxiv - Cell Biology 2022Quote: ... Apoptosis was induced in non-primed macrophages using the Bcl-2 inhibitor venetoclax (ABT-199, Tocris 6960) at 25 μM for 16 h ...
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bioRxiv - Neuroscience 2021Quote: ... IP3 receptors were blocked by bath application of 2-APB (100 µM, Tocris, Germany, micro-perfusion pump), 2-APB was applied at least 15 min prior t-LTP induction and was present throughout the recordings ...
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bioRxiv - Genomics 2022Quote: ... Media was then changed to CM Media supplemented with 2 μM Wnt-C59 (Tocris Biosciences, Bristol, UK) for 2 days prior to switching to CM Media without any supplements ...
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bioRxiv - Neuroscience 2022Quote: ... (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl-cyclopropanecarboxylate-dihydrochloride (NNC550396 or nnc) was purchased from TOCRIS and initially dissolved at 25 mM in water ...
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bioRxiv - Neuroscience 2024Quote: ... neurofibrillary tangles and related AD pathological structures were additionally stained using 1 µM 4,4’-[(2-methoxy-1,4-phenylene) di-(1E)-2,1-ethenediyl] bisphenol (MX-04) (Tocris) for 15 minutes at room temperature ...
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bioRxiv - Cancer Biology 2024Quote: From day 2-7 cells were cultured in SRM media supplemented with 0.1 µM LDN193189 (Tocris Biosciences), 10 µM SB431452(Tocris Biosciences) ...
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bioRxiv - Neuroscience 2023Quote: ... was selected by qualifying the presence of innervated cancer spheroids at various heights within the gel layer before stimulation with either 4 µM Bradykinin (Tocris/Biotechne, #3004) or 1 µM Capsaicin (Tocris/Biotechne ...
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bioRxiv - Developmental Biology 2021Quote: ... a combined medium was prepared by collecting 1mL of medium from the wells and mixing with same volume of fresh RPMI+B27 without insulin medium and supplemented with 5 µM IWP2 (Tocris). The medium was changed to 2mL RPMI+B27 without insulin at d5 ...
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bioRxiv - Neuroscience 2019Quote: ... Plates were spun at 200xg for five minutes to generate embryoid bodies (EBs) and were incubated in 5% CO2 at 37°C in cExN differentiation medium with 10µM Y-27632 (Tocris Biosciences). cExN differentiation medium components include Neurobasal-A (Life Technologies) ...
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bioRxiv - Neuroscience 2020Quote: ... In this method dual SMAD inhibition was performed using KOSR media supplemented with 10 μM ROCKi and SMAD inhibitors: 5 μM dorsomorphin (Tocris) and 10 μM SB431542 (Tocris ...
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bioRxiv - Neuroscience 2020Quote: ... placed in an aCSF-filled borosilicate glass pipette (3-5 MΩ) in the presence of 6,7-Dinitroquinoxaline-2,3-dione (DNQX; 10 μM; Tocris #14A/166549).
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... Alzet minipumps (model 1004) delivering either the high-affinity 5-HT2B antagonist SB204741 (Tocris Biosciences; 1 mg kg-1d-1) or vehicle (50% dimethyl sulfoxide [Sigma-Aldrich] and polyethylene glycol-400 [Fisher Chemical] ...
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bioRxiv - Cell Biology 2021Quote: ... MEFs WT and GPS2-KO cells were treated in the presence or absence of homoharringtonine (HHT) (5 μM, Tocris Bioscience) for 10 min to prevent new translation initiation ...
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bioRxiv - Neuroscience 2020Quote: ... Sections were washed with 1x PBS for three times and incubated with either 5 µM of Methoxy X04 (Tocris Bioscience) for 20 min at RT or 300 nM of DAPI for 10 minutes at RT ...
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bioRxiv - Neuroscience 2022Quote: ... animals were treated with the selective positive allosteric modulator (PAM) of mGluR5 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide (CDPPB; Tocris, UK) that was diluted in saline solution containing 5-10% final concentration of DMSO and polyethylene glycol 400 (DMSO ...
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bioRxiv - Neuroscience 2020Quote: Larvae were raised on small-batch Drosophila cornmeal dextrose medium (126) prepared with 5 μM L685,458 (Tocris Bioscience, Minneapolis, MN) and processed as above ...
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bioRxiv - Neuroscience 2020Quote: ... 1 mL/kg) or CNO (3.0 mg/kg i.p. in 95% saline, 5% DMSO, 1 mL/kg) (Tocris, Bristol, UK) in counterbalanced order ...