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1051 - 1100 of 1614 citations for 4 Bromo 3' 1 3 dioxolan 2 yl 2 fluorobenzophenone since 2020

• Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis

  Taisei Wakigawa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... BAI1 (Tocris, 2160, 1 μM), BTSA1 (Selleckchem ...
• NMDA receptor misalignment in iPSC-derived neurons from a multi-generational family with inherited Creutzfeldt-Jakob disease

  Nhat T.T. Le, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 1 μM Dorsomorphin (Tocris). After forming a dense neuro-epithelial sheet ...
• Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

  Laura von Schledorn, et al., bioRxiv - Bioengineering 2023

  Quote: ... 1 μM A83-01 (Tocris), 0.2 μM DMH-1 (Tocris ...
• Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

  Laura von Schledorn, et al., bioRxiv - Bioengineering 2023

  Quote: ... 0.2 μM DMH-1 (Tocris) and 5 μM Y-27632 [41] ...
• FAST-STEM: A Human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

  Aaron H. Rosenstein, et al., bioRxiv - Bioengineering 2024

  Quote: ... 0.25μM SANT-1 (Tocris bioscience) and 2μM all-trans retinoic acid (RA ...
• Isogenic hiPSC models of Turner syndrome development reveal shared roles of inactive X and Y in the human cranial neural crest network

  Darcy T. Ahern, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1 µM DMH1 (Tocris Bioscience), 20 ng/mL BMP4 (Peprotech) ...
• DLK-dependent axonal mitochondrial fission drives degeneration following axotomy

  Jorge Gómez-Deza, et al., bioRxiv - Neuroscience 2024

  Quote: ... P110 (1 µM, Tocris, 6897), BAPTA-AM (10mM Tocris 2787) ...
• A molecular switch for stress-induced activation of retrograde mitochondrial transport

  Christina Gladkova, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1 μM Thiamet G (Tocris), 0.5 mM TCEP (Sigma-Aldrich) ...
• Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss

  Anthony H. Tsang, et al., bioRxiv - Neuroscience 2024

  Quote: ... liraglutide 1 μg/μl (Tocris), lorcaserin 10 μg/μl (Generon ...
• Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

  Lizhen Wu, et al., bioRxiv - Immunology 2024

  Quote: ... or dTAGV-1 (Tocris, 6914) for 4 hours followed by 200 ng/ml dox treatment ...
• Suppressing PDGFRβ Signaling Enhances Myocyte Fusion to Promote Skeletal Muscle Regeneration

  Siwen Xue, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1 µM SU16F (Tocris 3304), or 1 µM Fludarabine (Tocris Bioscience ...
• GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory

  Hyun Jin Kim, et al., bioRxiv - Neuroscience 2024

  Quote: ... tetrodotoxin (TTX, 1 μM, Tocris) for blockade of sodium channel-mediated action potentials ...
• Genetically edited human placental organoids cast new light on the role of ACE2 in placental development

  Anya L. Arthurs, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1 µM A83-01 (Tocris), 50 ng/ml recombinant human epidermal growth factor (rhEGF ...
• D-Serine inhibits non-ionotropic NMDA receptor signaling

  Eden V. Barragan, et al., bioRxiv - Neuroscience 2024

  Quote: ... and 1 μM TTX (Tocris). Slices were pre-incubated with pharmacological reagents prior to imaging ...
• Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP

  T Fuchsberger, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1 µM TTX (Tocris Bioscience), 10 µM cycloheximide (Tocris Bioscience) ...
• Embryonic exposure to valproic acid and neonicotinoid deteriorates the developmental GABA switch and impairs long-term potentiation in the local circuit of intermediate medial mesopallium of chick telencephalon

  Toshiya Matsushima, et al., bioRxiv - Neuroscience 2024

  Quote: ... VU0463271 (1-10μM, Tocris Co.), bumetanide (20 μg/mL or 55 μM ...
• Effects of Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine on intracellular calcium, mitochondrial function, and viability in human nasal epithelial cells

  Joel C. Thompson, et al., bioRxiv - Physiology 2024

  Quote: ... and 1µM DMH-1 (Tocris) referred to as Growth Media (GM) ...
• Gz Enhanced Signal Transduction assaY (G_ZESTY) for GPCR deorphanization

  Luca Franchini, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... 1-oleoyl lysophosphatidic acid (Tocris), DAMGO (MedChemExpress) ...
• A molecular switch for stress-induced activation of retrograde mitochondrial transport

  Christina Gladkova, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1 μM Thiamet G (Tocris), 0.5 mM TCEP (Sigma-Aldrich) ...
• Bidirectional control of neurovascular coupling by cortical somatostatin interneurons

  Boubacar Mohamed, et al., bioRxiv - Neuroscience 2024

  Quote: ... BIBP3226 (1 µM, Tocris, 2707). Tetrodotoxin (TTX ...
• The multi-stage plasticity in the aggression circuit underlying the winner effect

  Rongzhen Yan, et al., bioRxiv - Neuroscience 2024

  Quote: ... we added 1% biocytin (Tocris) to the internal solution of whole-cell patch clamp recording and recorded the cell for at least 15 min before withdrawing the electrode ...
• The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity

  Roshni A. de Souza, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PD0325901 (1 µM) (Tocris, 4192) and LIF ...
• Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation

  Magdalena A. Sutcliffe, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1 μM CHRI99021 (Tocris 4423), 2.5 μM IWP2 ...
• Chronic BDNF simultaneously inhibits and unmasks superficial dorsal horn neuronal activity

  Sascha R.A. Alles, et al., bioRxiv - Neuroscience 2020

  Quote: ... and N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide (IEM-1460, Tocris) were prepared as 10 mM stocks dissolved in distilled water ...
• Amyloid-beta mediates homeostatic synaptic plasticity

  Christos Galanis, et al., bioRxiv - Neuroscience 2020

  Quote: ... Begacestat (1 μM; Tocris, Cat# 4283), KN-92 (5 μM ...
• A Self-Limiting Circuit Regulates Mammary Cap Cell Plasticity Through TGF-beta Signaling

  Armelle Le Guelte, Ian G. Macara, bioRxiv - Developmental Biology 2021

  Quote: ... BMP inhibitor (LDN193189, 1 μM, Tocris), JNK inhibitor (JNK-IN-8 ...
• Multiscale activity imaging in mammary gland reveals how oxytocin enables lactation

  Alexander J. Stevenson, et al., bioRxiv - Cell Biology 2020

  Quote: ... calphostin C (Tocris, 1626, 1 μM), dantrolene (Tocris ...
• Human cerebral tissues created via active cellular reaggregation produce functionally interconnected 3D neuronal network to mimic pathological circuit disturbance

  Aref Saberi, et al., bioRxiv - Bioengineering 2020

  Quote: ... 1 μM Dorsomorphin dihydrochloride (Tocris, 3093), 10 μM SB431542 (Tocris ...
• Calsyntenin-3, an atypical cadherin, suppresses inhibitory basket- and stellate-cell synapses but boosts excitatory parallel-fiber synapses in cerebellum

  Zhihui Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... (1) 10 μM CNQX (1045, Tocris) and 10 μM APV were included in ACSF ...
• Nogo-A Beyond the RhoA/ROCK Pathway – Novel Components of Intracellular Nogo-A Signaling Cascades

  Martina A. Maibach, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 nM JTE-013 (Tocris, 2392), 0.5 U Heparinase III (Sigma ...
• Dopaminergic neuromodulation of spike timing dependent plasticity in mature adult rodent and human cortical neurons

  Emma Louise Louth, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 μM gabazine (SR 95531, Tocris) was applied at the end of an STDP recordings ...
• Developmental Divergence of Sensory Stimulus Representation in Cortical Interneurons

  Rahel Kastli, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 µM TTX (Tetrodotoxin citrate, Tocris) was added to the circulating aCSF and 12 min after ...
• Delta Oscillations Are a Robust Biomarker of Dopamine Depletion Severity and Motor Dysfunction in Awake Mice

  Timothy C. Whalen, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 mg/kg SKF81297 (Tocris Biosciences), or 3 mg/kg quinpirole ...
• Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening

  Caroline E. Strong, et al., bioRxiv - Bioengineering 2022

  Quote: ... 1 mM cAMP (Tocris, cat# 1141), and 20 nM ascorbic acid (Tocris ...
• Cellular Mechanisms Underlying Central Sensitization in a Mouse Model of Chronic Muscle Pain

  Yu-Ling Lin, et al., bioRxiv - Neuroscience 2022

  Quote: ... and tetrodotoxin (TTX; 1 µM, Tocris) to block GABAA-receptor- ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... TAK1 inhibitor (1 μM, Tocris 3604), SB431542 (2 μM ...
• Augmentation of extracellular ATP synergizes with chemotherapy in triple negative breast cancer

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2022

  Quote: ... sodium polyoxotungstate or POM-1 (Tocris), PSB 069 (Tocris) ...
• Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia

  Silvia De Cicco, et al., bioRxiv - Neuroscience 2020

  Quote: ... LRRK2-IN-1 and GSK2578215A (Tocris).
• Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid-beta degrading enzyme in brain

  Per Nilsson, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 μM cyclo-SST (Tocris #3493), 100 nM CH275 (Tocris #2454) ...
• Purinergic signaling controls spontaneous activity in the auditory system throughout early development

  Travis A. Babola, et al., bioRxiv - Neuroscience 2020

  Quote: ... or MRS2500 (1 µM; Tocris, 2154) were added directly to the bath and allowed to equilibrate for 5 minutes before capturing an additional 5-minutes used for analysis of pharmacological block.
• Autologous humanized mouse models of iPSC-derived tumors allow for the evaluation and modulation of cancer-immune cell interactions

  Gaël Moquin-Beaudry, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and 1 μM A83-01 (Tocris). From day 10 to day 15 ...
• Preservation of prehearing spontaneous activity enables early auditory system development in deaf mice

  Calvin J. Kersbergen, et al., bioRxiv - Neuroscience 2022

  Quote: ... Application of MRS2500 (Tocris, 1 μM) was performed by superfusion by gravity of MRS2500-containing aCSF without interruption of continuous aCSF flow ...
• High Mobility Group Box 1 enhances ADP-mediated platelet activation by increasing platelet surface P2Y₁₂ localization

  Deirdre Nolfi-Donegan, et al., bioRxiv - Cell Biology 2021

  Quote: ... P2Y1 (MRS 2500, 1 nM; Tocris); P2Y12 (AR-C 66096 ...
• New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

  Fangmiao Sun, et al., bioRxiv - Neuroscience 2020

  Quote: ... and/or 1 μM Halo (Tocris), SCH-23390 (Tocris) ...
• Reconstructing human early embryogenesis in vitro with pluripotent stem cells

  Berna Sozen, et al., bioRxiv - Developmental Biology 2021

  Quote: ... (S)-(+)-Dimethindenemaleate (D, 1 mM; Tocris, 1425) and Minocycline hydrochloride (M ...
• Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro

  Ziad Al Tanoury, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 μM Chiron (Tocris, Cat. # 4423), 0.2% Pen/Strep (Life Technologies ...
• The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport

  HA Bustamante, et al., bioRxiv - Cell Biology 2020

  Quote: ... Torin-1 was purchased from Tocris Bioscience (Bristol ...
• Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro

  Ziad Al Tanoury, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 μM Chiron (Tocris, Cat. # 4423), 0.2% Pen/Strep (Life Technologies ...
• High-Throughput Human Primary Cell-Based Airway Model for Evaluating Influenza, Coronavirus, or other Respiratory Viruses in vitro

  A.L. Gard, et al., bioRxiv - Microbiology 2020

  Quote: ... 1 μM A-83-01 (Tocris), 0.2 μM DMH-1 (Tocris) ...
• Leveraging complex interactions between signaling pathways involved in liver development to robustly improve the maturity and yield of pluripotent stem cell-derived hepatocytes

  Claudia Raggi, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and 1 μM A83-01 (Tocris) for 5 days ...