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Citations for Tocris :
1001 - 1050 of 1081 citations for 2 Amino 6 8 dimethyl 3 phenylquinoline hydrochloride since 2020
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2021Quote: ... Eye movements were prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Neuroscience 2020Quote: ... Eye movements were prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Neuroscience 2021Quote: ... the same routine was repeated in the presence of the glutamate transport blocker TFB-TBOA 2 μM (Tocris). For both traces the fluorescence change was calculated from the average of the baseline fluorescence intensities for each ROI as ΔF/F = (FSBFI - FSBFI(baseline)/FSBFI(baseline) ...
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bioRxiv - Biochemistry 2021Quote: ... cells were treated with either DMSO or 1 µM of LRRK2 kinase inhibitor (MLi-2, cat.no. 5756, TOCRIS) for 90 mins and then examined for localization ...
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bioRxiv - Cell Biology 2020Quote: ... the γ-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine1,1-dimethylethyl ester (DAPT) (Tocris) was added at a concentration of 5 μM ...
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bioRxiv - Neuroscience 2022Quote: Rats were bilaterally infused with either the selective α4β2 nicotinic antagonist DHβE (low dose: 15μg/.5μL/side, high dose 30μg/.5μL/side; Tocris Bioscience, Bristol, UK) the non-selective dopamine receptor antagonist Flupenthixol (15μg/.5μl/side ...
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bioRxiv - Biophysics 2022Quote: ... the 2-methylphenylureaphenylacetyl (MUPA) moiety with LDVPAAK peptide (MUPA-LDVPAAK; now commercially available, Tocris, 7020, supplementary Fig. 12) was custom synthesized by Bio-Synthesis and the amine group of its lysine side chain was reacted with the NHS group of sulfo-SMCC ...
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bioRxiv - Cell Biology 2022Quote: ... LPS was washed off and the macrophages were treated with 2 μM MK6-83 (cat no. 5547, Tocris), 20 μM MLSA-1 (cat ...
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bioRxiv - Genomics 2023Quote: ... and seeded at a seeding density of 10,000–25,000 cells/cm2 in mTeSR supplemented with 2 μM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Neuroscience 2023Quote: ... Candidate ASM order information was as follows: 1-Ethyl-2-benzimidazolinone (Alternative name 1-EBIO, Tocris, CAS: 1041), AA43279 (Focus biomolecules ...
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bioRxiv - Neuroscience 2023Quote: All recordings were done in ACSF-2 without or with 10 μM DQP 1105 (Tocris Bio-Techne, France), 10 μM DQP 1105 + 1μM Ro 25-6981 (Tocris Bio-Techne ...
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bioRxiv - Neuroscience 2023Quote: ... GRP was applied to the spinal cord to evoke Ca2+ oscillations and 2-APB (100 µM, Tocris 1224) 10 min later ...
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bioRxiv - Biophysics 2023Quote: ... whereas IS-2 sample was made up to 100 µM CTZ and 100 µM GYKI- 52466 (Tocris, 1454) prior to centrifugation (75,000 g ...
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bioRxiv - Neuroscience 2021Quote: ... and nor-Binaltorphimine dihydrochloride (norBNI, KOR antagonist, 10 mg/kg, i.p.) (CAS# 113158-34-2) were obtained from Tocris and dissolved in 0.9% sterile saline ...
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bioRxiv - Biochemistry 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy] butanoic acid (DCPIB) was purchased from Tocris Bioscience and reconstituted to 50 mM in DMSO ...
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bioRxiv - Cell Biology 2022Quote: To observe chromosome alignment in fixed-cell experiments – with the advantage of taking high resolution images and easily selecting many cells for further analysis - cells were released from thymidine block for 7 hours before being treated for 2 hours with RO-3306 (10μM, Tocris) – to synchronise cells at the G2/M boundary - or with a 3-hour treatment with STLC (10μM ...
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bioRxiv - Biophysics 2022Quote: ... 100 μM 2-APB blocking stretch-activated inositol triphosphate receptors (InsP3Rs) on the ER/nuclear membranes (Tocris Bioscience #1224), 100 μM CK-666 (Tocris Bioscience #3950 ...
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bioRxiv - Neuroscience 2020Quote: ... were performed on mice with no knee injections 20 min before and after C21 (2 mg/kg diluted in sterile saline from a stock of 100 mM in ethanol, i.p., Tocris) injection.
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bioRxiv - Cell Biology 2021Quote: ... AKT (20 μM MK2206, Cayman Biochemicals #1032350-13-2) and myosin ATPase activity inhibitor (5 μM Blebbistatin, Tocris #1852).
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bioRxiv - Immunology 2020Quote: ... 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid (DCPIB, 1540) was from Tocris. NS3728 and NBC19 were made at the University of Manchester.
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bioRxiv - Cell Biology 2023Quote: ... 3- (4,5-dimmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays were used to estimate cell number following the manufacturer’s description (Tocris, # 5224), and absorbance was measured at 550 nm in an EnsightTM 96-well plate reader (Perkin Elmer).
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bioRxiv - Molecular Biology 2023Quote: ... BI stands for Broccoli aptamer ligand (5Z)-3-(1H-Benzimidazol-7-ylmethyl)-5-[(3,5-di-fluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-4H-imidazol-4-one dihydrochloride) (Cat. No. 7466, Tocris) (14) ...
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Self-organised pattern formation in the developing neural tube by a temporal relay of BMP signallingbioRxiv - Developmental Biology 2023Quote: ... cells were dissociated from the 100 mm dishes and 2.8-3M cells per well were seeded on the prepared 2-well dishes in N2B27 medium with 10ng/ml bFGF + 10µM Y-27632 ROCK inhibitor (Tocris) media for 3h ...
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bioRxiv - Neuroscience 2024Quote: ... Eye movements were further prevented by injection of α-bungarotoxin (1 nL of 2 mg/ml; Tocris, Cat: 2133) into the ocular muscles behind the eye.
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bioRxiv - Cell Biology 2024Quote: ... supplemented with 5.5 mM glucose prior to sequential 30 min incubations of KRBH containing low (2 mM) and high (20 mM) glucose with or without 2.5 nM GIP (Tocris Bioscience ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... adrenergic agonist Xylazine Chloride (XYL, 2% m.V-1, Anasedan®) and opioid agonist Ala2-MePhe4-Gliol5-encephalin (DAMGO, Tocris) and their specified doses were diluted to a final injection volume of 20µL either in sterile NaCl 0,9% m.V-1 (saline ...
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bioRxiv - Neuroscience 2024Quote: Recordings were performed at ∼34°C in ACSF (flow rate 2–4 ml / min) containing inhibitory receptor blockers picrotoxin (20µM; Tocris), CGP 55845 (1µM ...
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bioRxiv - Biochemistry 2024Quote: ... with or without the gamma-secretase inhibitor (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester (DAPT; Tocris, 2634) at a final concentration of 10 µM ...
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bioRxiv - Neuroscience 2020Quote: ... They were left drug-free for 3 weeks before chronic daily treatment with vehicle (NaCl 0.9%) or VU0155041 (Tocris, Bristol, UK; 2.5 or 5 mg/kg, i.p.) started ...
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bioRxiv - Developmental Biology 2021Quote: ... (15) ESC were grown in N2B27 media supplemented with 2i/LIF (1 mM PD0325901, 3 mM CHIR99021, both from Tocris and 1:500 LIF, made in house). N2B27 media consisted of a 1:1 mix of DMEM/F12 and Neurobasal Medium ...
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bioRxiv - Neuroscience 2021Quote: ... Four of the rats were also infused with 2 μL of either physiological saline or 5 μg/μL yohimbine (Tocris) with a flow rate of 0.5 μL/min as previously reported (Caetano et al. ...
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bioRxiv - Genomics 2020Quote: ... The involvement of the TLR1/2 in signal transduction was tested using CU-CPT22 at 10 µM (Tocris Bioscience, UK). The used concentrations of inhibitors were selected based on recommendations provided by the manufacturers ...
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bioRxiv - Neuroscience 2020Quote: ... and the Mai Tai eHP was tuned to 725nm for photoactivation of recirculated caged MNI-L-glutamate (2 mM, Tocris)57,58 ...
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bioRxiv - Neuroscience 2020Quote: ... or by either bath application or using a custom-made perfusion system (for imaging cells on 12-mm coverslips): 2-AG (Tocris), AEA (Cayman) ...
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bioRxiv - Neuroscience 2021Quote: Potassium currents were isolated pharmacologically during whole-cell voltage-clamp recordings by blocking fast sodium and calcium channels as well as ionotropic receptors for GABA and glutamate (2 µM tetrodotoxin (TTX, Tocris), 300 µM NiCl2 ...
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bioRxiv - Neuroscience 2022Quote: ... the AMPA/NMDA receptor agonist kynurenic acid (2 mM) and the GABA-A receptor antagonist picrotoxin (PTX; 100 uM, Tocris) were present ...
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bioRxiv - Cancer Biology 2022Quote: ... and 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazoledihydro-chloride (MPP; cat# 1991) were purchased from Tocris Bioscience ...
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A Bidirectional Switch in the Shank3 Phosphorylation State Biases Synapses toward Up or Down ScalingbioRxiv - Neuroscience 2021Quote: ... 6 hrs (Figure 6 – figure supplement 2) or 24 hrs after transfection (the remaining experiments) neurons were treated with tetrodotoxin (TTX, 5 µM, Tocris) for ∼16 hours ...
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bioRxiv - Cell Biology 2021Quote: ... and seeded at a seeding density of 10000-25000 cells/cm2 in mTeSR supplemented with 2 µM ROCK inhibitor Y27632 (Tocris) onto laminin-521 coated plates ...
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bioRxiv - Cancer Biology 2021Quote: ... and single-cell suspensions were re-plated in mTeSR1 supplemented with 2 µM ROCK inhibitor (Y-27632 Dihydrochloride Tocris #1254). Transgenic WT29 iPSCs were generated by transfecting PiggyBac expression vector and pBase (Villegas et al ...
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bioRxiv - Neuroscience 2020Quote: The FPR2 agonist Compound-43 (N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea) and antagonist WRW4 (Trp-Arg-Trp-Trp-Trp-NH2) were purchased from Tocris Ltd ...
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bioRxiv - Cell Biology 2022Quote: Compounds which were considered a hit after library screening were purchased from the following commercial suppliers: 2-TEDC (Tocris Bioscience), Anethole-trithione (ATT ...
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bioRxiv - Pathology 2022Quote: About 0.1 to 0.2 MOI (Multiplicity of Infection) equivalent of VSV-G and pseudotype SARS-CoV-2 spike virus particles were treated with recombinant LL37 (Tocris) and niacinamide (vitamin B3 ...
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bioRxiv - Cell Biology 2022Quote: ... resuspended in DMEM-1%BSA and incubated in suspension for 30 min at 37°C in 10% CO2 and 2 μg/ml CT04 (#CT04-A, Cytoskeleton or 10 μM EHT1864 (#3872, Tocris). The vehicle control included the corresponding dilution of DMSO as needed ...
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bioRxiv - Microbiology 2024Quote: ... the cells were hybridized with V-EV71-C1 probe (Biotechne) at 40°C for 2 hours and then the signals were revealed using TSA Vivid 570 kit (Tocris). The slides were then incubated with blocking buffer and incubated with MAB979 (1:100 ...
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bioRxiv - Neuroscience 2024Quote: ... another group of animals received an ip injection of WIN55,212-2 (0.5 mg/kg) along with CB1 receptor antagonist SR141716A (0.5 mg/kg, ip) (Tocris Bioscience, Bristol, UK). Rats were randomly selected for each group ...
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bioRxiv - Neuroscience 2023Quote: Adherent human iPSCs were grown to near confluence before the differentiation to heterogenous spinal/hindbrain neurons was initiated by changing the media for two days to media d1-2 (200 nM LDN193189 [Tocris, 6053] ...
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bioRxiv - Neuroscience 2023Quote: Adherent human iPSCs were grown to near confluence before the differentiation to heterogenous spinal/hindbrain neurons was initiated by changing the media for two days to media d1-2 (200 nM LDN193189 [Tocris, 6053], 10 µM SB431542 [Tocris, 1614] ...
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bioRxiv - Cell Biology 2023Quote: ... Cells were cultured in an ad hoc defined generic medium (Supplementary Table 2) supplemented with Rho-kinase inhibitor (ROCKi; Tocris) and Primocin ...
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bioRxiv - Neuroscience 2023Quote: ... and (3-chloro-4-fluoro-N-[(4-([2-(phenylcarbonyl)hydrazino]carbonyl) phenyl)methyl]benzene-sulfonamide) (TCN-201) (Hansen et al., 2012)were obtained from Tocris Bioscience ...