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Citations for Tocris :
951 - 987 of 987 citations for 6 AMINO 3 HYDROXY PYRIDO 2 3 B PYRAZINE 2 CARBOXYLIC ACID since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2021Quote: ... or the AMPA-iGluR specific inhibitor 2,3-dioxo-6-nitro-7-sulfamoyl-benzo[f]quinoxaline (NBQX, cat. num. 373, Tocris). Drugs were dissolved in ESC complete media (no 2i ...
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bioRxiv - Neuroscience 2022Quote: ... were recorded during the application of the competitive AMPA/kainate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 20 μM, Tocris) and the selective NMDA receptor antagonist amino-5-phosphonopentanoic acid (AP5 ...
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bioRxiv - Neuroscience 2019Quote: ... 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide (“NBQX”, 100 mM in DMSO, Tocris Cat No 0373); D-2-amino-5-phosphonovalerate (“D-AP5” ...
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bioRxiv - Molecular Biology 2022Quote: ... 6 replicates of each condition were treated with DMSO or 100 nM dTAG13 (Tocris Bioscience, Fisher Scientific 66-055) for 2 hours ...
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bioRxiv - Neuroscience 2023Quote: ... slices were incubated in recording ACSF supplemented with 5 μM 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX, Tocris, 1045) and 100 μM D-(−)-2-Amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Neuroscience 2022Quote: ... drugs were bath applied at the following concentrations (in μM): 10 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX, Tocris), 50 D-2-amino-5-phosphonopentanoic acid (D-APV ...
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bioRxiv - Cell Biology 2022Quote: ... Neuroectoderm was induced for 6 days in CDM-BSA supplemented with 12ng/ml FGF2 and 10μM SB431542 (Activin/Nodal/TGFβ inhibitor; Tocris), as previously described34 ...
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bioRxiv - Immunology 2023Quote: Co-culture assays: thymocytes were isolated from untreated C57BL/6 mice and incubated with Nigericin (10 µM, Tocris, 4312) and LPS (1 ng/ml ...
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Sexual differences in neuronal and synaptic properties across subregions of the mouse insular cortexbioRxiv - Neuroscience 2023Quote: ... were recorded at −70mV in presence of 20□μM CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione disodium, an AMPA receptor antagonist, Tocris) and L-APV 50 μM (DL-2-Amino-5-phosphonopentanoic acid ...
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bioRxiv - Neuroscience 2021Quote: ... Glutamatergic neurons were identified by their characteristic EPSC time course and by sensitivity of EPSC to application of glutamate receptor antagonist kynurenic acid (Tocris). Synaptic currents were acquired at 10 kHz using pClamp 10.2 software (Molecular Devices ...
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bioRxiv - Neuroscience 2021Quote: ... and GluN2BGC−/− mice (P40 – P60) were stereotactically injected with 50 nl of 20 mM solution of kainic acid (Tocris / Biotechne) in 0.9 % NaCl to the left CA1 area of the dorsal hippocampus (AP −1.8 mm ...
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bioRxiv - Neuroscience 2022Quote: Astrocytes grown in 6-well plates were refreshed with glial maintenance media or glial maintenance media supplemented with 100 μM L-Glutamic Acid (Tocris) for 3 h ...
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bioRxiv - Cell Biology 2023Quote: ... (Optopharma Ltd.) and 20 nM for 1-Oleoyl lysophosphatidic acid sodium salt (LPA) (5 mM stock dissolved in water) (Tocris). As controls ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141], 2.5 µM DAPT [Tocris, 2634] ...
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bioRxiv - Developmental Biology 2021Quote: ... coated 12-well plates at the density of 6×105 cells/well in mTeSR1 medium supplemented with 10 μM ROCK inhibitor (Y-27632, Tocris). The medium was changed daily ...
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bioRxiv - Neuroscience 2021Quote: ... C57BL/6 wild-type mice were daily treated with vehicle or clemastine (#1453 Tocris; 50mg/kg solved in 10% DMSO) by intraperitoneal injections from postnatal day 5 (P5 ...
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bioRxiv - Molecular Biology 2020Quote: ... kin28as strains and their controls were then grown to an OD600 of 0.8 and treated with 6 μM of 1-Naphthyl PP1 (NAPP1; Tocris Bioscience) for 15 min ...
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bioRxiv - Neuroscience 2021Quote: ... 10 μM NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline) and 50 μM AP-5 (Tocris Bioscience, UK) were applied in the bath to block excitatory synaptic responses.
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bioRxiv - Neuroscience 2022Quote: Primary microglia cells from C57Bl/6 J mice cultured in presence of CSF-1 were treated with Formoterol (10 ng/ml, cat # 1448, Tocris) or vehicle for 1 hour ...
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bioRxiv - Neuroscience 2023Quote: ... Neuronal activity was manipulated either with field stimulation (100mA,10 Hz,600 AP) or 6 hours of 50 µM picrotoxin (PTX, Tocris) treatment 65 ...
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bioRxiv - Cancer Biology 2023Quote: Around 1 x 105 cells were seeded in a 6-well plate for the drug treatment with Brequinar (Tocris, 6196) in a dose-dependent manner for 72 h ...
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bioRxiv - Molecular Biology 2023Quote: ... Male Sprague Dawley (SD) rats (6-10 weeks old) were administered with a single dose of Sugen 5416 (SU) (20mg/kg, Tocris) delivered in CMC vehicle (as previously described)16 or DMSO and placed in hypoxia chambers (10% O2 ...
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bioRxiv - Neuroscience 2023Quote: ... one day of medium d10 (Medium d3–9 with 200 µM ascorbic acid [Sigma-Aldrich, A4403], 125 µM db-cAMP [Tocris, 1141] ...
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bioRxiv - Neuroscience 2023Quote: ... Mice were injected intraperitoneally (i.p.) with 5.0mg/kg synthetic kainic acid (KA) dissolved in 0.9% saline (#7065, Tocris Bioscience, Bristol, United Kingdom). At twenty-minute intervals ...
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bioRxiv - Neuroscience 2021Quote: ... The bath solution usually contained 6,7-dinitroquinoxaline-2,3-dione (DNQX, 10 µM) and D- aminophosphonovaleric acid (D-APV, 50 µM) to block ionotropic glutamate receptors (Tocris, Abingdon, United Kingdom). Patch electrodes had resistances of 4-6 MΩ when filled with KMeSO4- or CMeSO4-based internal solution (same as used in vivo) ...
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bioRxiv - Immunology 2020Quote: ... These cells were then directed to become proepicardial cells by the addition of retinoic acid and WNT CHIR 99021 followed by TGFβ inhibition (SB431542, Tocris Bioscience 1614). Finally ...
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bioRxiv - Neuroscience 2023Quote: ... and cells were centrifuged at 200 rcf for 5 min and resuspended in N2B27 with the same supplements as on day 0 except for the removal of Y27632 and addition of all-trans retinoic acid (100 nM; Tocris, 0695/50) and SAG (500 nM ...
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Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s diseasebioRxiv - Neuroscience 2020Quote: ... Cells were dissociated into a single-cell suspension using accutase and seeded at a density of 1.0 x 106 cells per well on Matrigel coated 6-well plates in mTeSR1 supplemented with 10 mM ROCK inhibitor Y-27632 (Tocris, 1254).
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bioRxiv - Neuroscience 2022Quote: ... and singularized cells were seeded at a defined density (between 42,000 and 62,000 cells/cm2 depending on the hiPSC line) on matrigel coated 6-well plates in StemMACS iPS-Brew supplemented with 10 µM Y27632 (ROCK inhibitor, Tocris Bioscience). After 24 h (Fig ...
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bioRxiv - Cell Biology 2020Quote: ... hESCs were induced with chemically defined medium (CDM3, containing RPMI/1640, AA and BSA) as the basal medium [30] containing 6 μM CHIR99021 (Tocris Bioscience) from day 0 to day 2 ...
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bioRxiv - Neuroscience 2020Quote: Adult (12-13 week old) male C57BL/6 mice received daily intraperitoneal (i.p.) injections of ADRβ3 agonist CL316,243 (Tocris Bioscience, Bristol, U.K.; Cat # 1499), at 1.0 mg/kg BW or an equivalent amount of sterile saline ...
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bioRxiv - Cancer Biology 2019Quote: ... ARL 67156 Trisodium Salt (6-N,N-Diethyl-D-β,γ-dibromomethyleneATP trisodium salt) and POM 1(Sodium metatungstate) were obtained from Tocris Bioscience ...
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bioRxiv - Neuroscience 2022Quote: ... the medium was replaced with HBSS containing 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate (ARL 67156; Tocris, 1283) at a concentration of 100 μM ...
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bioRxiv - Cell Biology 2023Quote: ... and distributed to 6-well low-attachment plates containing primitive streak/embryoid body media (10 μM Y-27632 (Tocris/Biotehne, Minneapolis, MN), 3 ng/ml BMP4 (R&D/Biotechne ...
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bioRxiv - Neuroscience 2021Quote: ... A glass micropipette (tip diameter ∼ 30 µm) containing a 0.5M GABA solution (γ-aminobutyric acid; 0344, Tocris; dissolved in 0.9% w/v NaCl solution) was then advanced into the brain using a zero-drift micromanipulator under stereotaxic control ...
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bioRxiv - Neuroscience 2022Quote: ... dissociated hiPSCs were plated at 1×104 cells/cm2 into 6-well plates in the presence of 10 µM ROCK inhibitor (Y-27632, Tocris Bioscience, Bristol, UK). Cortical and hypothalamic differentiation took place on a substrate of geltrex (1:100 ...
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bioRxiv - Neuroscience 2023Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...