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51 - 100 of 755 citations for 2 3 Cyclohexenyl Ethyltrimethoxysilane since 2020

• Synaptic vesicles transiently dock to refill release sites

  Grant F Kusick, et al., bioRxiv - Neuroscience 2020

  Quote: ... NBQX (3 μM; Tocris) and bicuculline (30 μM ...
• Cell trajectory modeling identifies a primitive trophoblast state defined by BCAM enrichment

  Matthew Shannon, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 3 µM CHIR99021 (Tocris), and 2 µM Y-27632 (EMD Millipore) ...
• Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies

  Young-Jun Choi, et al., bioRxiv - Cell Biology 2021

  Quote: ... CHIR99021 (3 μM; Tocris), 10058-F4 (25 and 50 μM ...
• Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context

  Luigi Russo, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 3 μM CHIR99021 (Tocris) was added to the medium from day 3 onwards ...
• Aging affects K_V7 channels and perivascular-adipose tissue-mediated vascular tone

  Yibin Wang, et al., bioRxiv - Physiology 2021

  Quote: ... 3 µM XE991 (Tocris).
• Single-cell assessment of trophoblast stem cell-based organoids as human placenta-modeling platforms

  Matthew J. Shannon, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 3 μM CHIR99021 (Tocris) and 1 μM Y-27632 (EMD Millipore ...
• Synaptotagmin 7 is enriched at the plasma membrane through γ-secretase processing to promote vesicle docking and control synaptic plasticity in mouse hippocampal neurons

  Jason D. Vevea, et al., bioRxiv - Neuroscience 2021

  Quote: ... NBQX (3 μM; Tocris) and bicuculline (30 μM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CHIR99021 (3 μM, Tocris), and FGF2 (20 ng/mL ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CHIR99021 (3 µM; Tocris), FGF2 (20 ng/mL ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... CHIR99021 (3 μM; Tocris), and A8301 (1 μM ...
• Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells

  Matias I. Autio, et al., bioRxiv - Bioengineering 2021

  Quote: ... 3 μM CHIR99021 (Tocris) and 10 μM LY294002 (LC Labs ...
• mSWI/SNF interacts with the ribosome and its inhibition/mutations alter translation and sensitize to mTOR/PI3K inhibitors

  Livia Ulicna, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and PFI-3 (Tocris) inhibitors were used at the indicated concentrations on cells seeded since 24 to 72 hours.
• Heparin protects human neural progenitor cells from Zika Virus-induced cell death and preserves their differentiation into mature neural-glia cells

  Isabel Pagani, et al., bioRxiv - Microbiology 2021

  Quote: ... 3 µM CHIR99021 (Tocris), 10 µM SB-431542 (Miltenyi ...
• Synapse specific and plasticity-regulated AMPAR mobility tunes synaptic integration

  Agata Nowacka, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 QX314Cl (Tocris, #2313) and 0.15 spermine (Sima-Aldrich ...
• LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

  Riccardo Sirtori, et al., bioRxiv - Neuroscience 2024

  Quote: ... CHIR99021 (3 μM, Tocris), DMH1 (2 μM ...
• Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release

  Zhenyong Wu, et al., bioRxiv - Neuroscience 2023

  Quote: ... NBQX (3 μM; Tocris) and bicuculline (30 μM ...
• Med12 cooperates with multiple differentiation signals to enhance embryonic stem cell plasticity

  Max Fernkorn, Christian Schröter, bioRxiv - Cell Biology 2024

  Quote: ... 3 μM CHIR99201 (Tocris) and 10 ng/ml LIF (protein chemistry facility ...
• Medial Prefrontal Cortex Serotonin Input Regulates Cognitive Flexibility in Mice

  Ashlea A. Morgan, et al., bioRxiv - Neuroscience 2023

  Quote: ... bicuculline (3 µM; Tocris) that was used to block GABA receptors ...
• IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated Amyotrophic Lateral Sclerosis

  Amanda Faria Assoni, et al., bioRxiv - Neuroscience 2022

  Quote: ... CHIR99021 (3 μM) (Tocris) and Ascorbic acid (0.1 mM ...
• Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling

  Evan T Hoffman, et al., bioRxiv - Cell Biology 2024

  Quote: ... 3 μM CHIR99021 (Tocris), 1x Insulin-Transferrin-Selenium (ITS ...
• ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis

  Kathryn M. Yammine, et al., bioRxiv - Genetics 2024

  Quote: ... 3 μM C59 (Tocris) and 0.5 μM PD0325901 (Selleck Chemicals) ...
• Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II

  Kathryn M. Yammine, et al., bioRxiv - Cell Biology 2024

  Quote: ... 3 μM C59 (Tocris) and 0.5 μM PD0325901 (Selleck Chemicals) ...
• WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm

  Connor Ross, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 3 µM CHIR99021 (Tocris) and 10 ng/mL mouse recombinant LIF (Cambridge Stem Cell Institute or Peprotech) ...
• Prenatal Methadone Exposure Disrupts Behavioral Development and Alters Motor Neuron Intrinsic Properties and Local Circuitry

  Gregory G. Grecco, et al., bioRxiv - Neuroscience 2020

  Quote: ... The bath solution for recordings contained elevated concentrations of divalent cations [4 mM Ca2+ and 4 mM Mg2+] and NMDA receptor antagonist 3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP) [5 mM] (Tocris biosciences, 126453-07-4). Slices were used 1.5–4.5 hours after preparation ...
• Copy Number Variation at 16p11.2 Imparts Transcriptional Alterations in Neural Development in an hiPSC-derived Model of Corticogenesis

  Julien G. Roth, et al., bioRxiv - Neuroscience 2020

  Quote: ... 3 µm CHIR (Tocris, 4423) and 20 ng/ml FGF2 (R&D Systems ...
• Defining totipotency using criteria of increasing stringency

  Eszter Posfai, et al., bioRxiv - Cell Biology 2020

  Quote: ... 3 µM CHIR99021 (Tocris 4423); 2 µM Dimethindene maleate (Tocris #1425) ...
• Defining totipotency using criteria of increasing stringency

  Eszter Posfai, et al., bioRxiv - Cell Biology 2020

  Quote: ... 3 µM CHIR99021 (Tocris 4423); and 1000 U/mL mouse LIF (generated in-house) ...
• Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

  Young Sun Hwang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience) and 10 μM of a ROCK inhibitor ...
• Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis

  Chloé Berland, et al., bioRxiv - Neuroscience 2021

  Quote: ... AM251 (3 mg/kg, Tocris), AM6545 (10 mg/kg ...
• A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

  Kunimichi Suzuki, et al., bioRxiv - Neuroscience 2020

  Quote: ... CGP 55845 (3 μM, Tocris), and tetrodotoxin (Tocris ...
• Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context

  Luigi Russo, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 3 μM CHIR99021 (Tocris) or 50 ng/ml Activin A (Peprotech) ...
• Kinetochores respond to subtle changes in the stability of microtubule attachments

  Jessica D. Warren, et al., bioRxiv - Cell Biology 2021

  Quote: ... ZM447439 (3 μM; Tocris Bioscience), Okadaic Acid (100 nM ...
• C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein

  Yuma Kato, et al., bioRxiv - Neuroscience 2021

  Quote: ... 3 μM SB431542 (Tocris, UK), and 3 μM CHIR99021 (Focus Biomolecules ...
• Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord

  Kalaimakan Hervé Arulkandarajah, et al., bioRxiv - Neuroscience 2020

  Quote: ... gabazine (3 μM, Tocris, USA), CNQX Disodium (20 μM ...
• LTD at amygdalocortical synapses as a novel mechanism for hedonic learning

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Altered Thalamocortical Signaling in a Mouse Model of Parkinson’s Disease

  Olivia K. Swanson, David Richard, Arianna Maffei, bioRxiv - Neuroscience 2020

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Erev[Cl−] = −49.8mV)) ...
• CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cells development

  Young Sun Hwang, M. Andrés Blanco, Kotaro Sasaki, bioRxiv - Developmental Biology 2022

  Quote: ... 3 μM CHIR99021 (Tocris Bioscience) and 10 μM of a ROCK inhibitor ...
• Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

  Jeonghwan Youk, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 3 μM CHIR99021 (Tocris)) was added to each lower chamber ...
• MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

  Anne Bourdais, Benoit Dehapiot, Guillaume Halet, bioRxiv - Cell Biology 2022

  Quote: ... IPA-3 (1 μM; Tocris), BDP-9066 (1 μM ...
• Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons

  Yoshifumi Sonobe, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 3 µM CHIR99021 (Tocris Bioscience), 2 µM DMH1 (Tocris Bioscience) ...
• Design, implementation, and functional validation of a new generation of microneedle 3D high-density CMOS multi-electrode array for brain tissue and spheroids

  Lisa Mapelli, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 μM TTX (tetrodotoxin, Tocris) was added to the Krebs solution ...
• An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• Inhibitory gating of thalamocortical inputs onto rat gustatory insular cortex

  Melissa S. Haley, et al., bioRxiv - Neuroscience 2022

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (Vrev [Cl−1] = −49.3mV) ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... CHIR99021 3 μM (4423, Tocris), holo-transferrin 10 μg/ml (T0665 Sigma) ...
• Electron microscopic analysis of the influence of iPSC-derived motor neurons on bioengineered human skeletal muscle tissues

  Christine T. Nguyen, et al., bioRxiv - Cell Biology 2023

  Quote: ... 3 μM CHIR99021 (Tocris 4423) and 200 μM ascorbic acid (Sigma-Aldrich ...
• Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation

  Sina Schumacher, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 µM CHIR99021 (Tocris), referred to as 2i + LIF.33 N2B27 was prepared as a 1:1 mixture of DMEM/F12 and Neuropan Basal Medium (both from PAN Biotech) ...
• Ca²⁺-sensing receptor regulates neuronal excitability via Kv7 channel and G_i/o protein signalling

  Nontawat Chuinsiri, et al., bioRxiv - Physiology 2023

  Quote: ... 3 μM CHIR-99021 (Tocris), 200 μM L-ascorbic acid (Merck) ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 3 μM CHIR99021 (Tocris). In base control strategy #14 ...
• Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

  Renée Moerkens, et al., bioRxiv - Cell Biology 2024

  Quote: ... CHIR99021 (3 μM, Tocris, #4423) and defined FBS (2% vol/vol ...
• Modulation of sweet preference by neurosteroid-sensitive, δ-GABA_A receptors in adult mouse gustatory insular cortex

  Priscilla E Yevoo, et al., bioRxiv - Neuroscience 2024

  Quote: ... 3 QX-314 (Tocris Bioscience), 0.2% biocytin (reversal potential (Vrev)[Cations] = 10mV) ...