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901 - 908 of 908 citations for 7 7 DIMETHOXY HEPT 1 YNE since 2019

• SRC family kinase inhibition rescues molecular and behavioral phenotypes, but not protein interaction network dynamics, in a mouse model of Fragile X syndrome

  Vera Stamenkovic, et al., bioRxiv - Neuroscience 2023

  Quote: ... was dissolved in HEPES-aCSF in the presence of non-mGluR glutamate receptor blockers (CNQX, Tocris, 0190, 40 µM; Nimodipine, Tocris, 0600, 1 µM; D(-)-2-Amino-5 phosphonopentanoic acid (APV) ...
• Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells

  Saeko Akiyama, et al., bioRxiv - Cell Biology 2023

  Quote: ... 20 μM forskolin (solvent: DMSO, 063-02193, Fujifilm Wako Pure Chemicals, Osaka, Japan) and 1 μM LDN193189 (solvent: DMSO, 6053-10, Tocris Bioscience Bristol United Kingdom), with an induction period of 10 days.
• The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function

  Subhrajit Banerjee, et al., bioRxiv - Cell Biology 2024

  Quote: The PM fluidity of mammalian cells was measured using 3-((3-((9-(Diethylamino)-5-oxo-5H-benzo[a]phenoxazin-2-yl)oxy)propyl)(dodecyl)(methyl)ammonium)propane-1-sulfonate (NR12S; Tocris Bioscience Cat. No. 7509) using a method as exactly mentioned in Wendy S ...
• Rescue of Impaired Blood-Brain Barrier in Tuberous Sclerosis Complex Patient Derived Neurovascular Unit

  Jacquelyn A. Brown, et al., bioRxiv - Neuroscience 2023

  Quote: ... for 18-30 minutes and reseeding them into Matrigel (BD Bioscience #354277)-coated 6-well plates at 1 x 105 cells/cm2 in cortical differentiation medium containing 10 µM Rock-inhibitor (Tocris, Minneapolis, MN, USA #1254), which was removed after 24 hours ...
• FAST-STEM: A Human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

  Aaron H. Rosenstein, et al., bioRxiv - Bioengineering 2024

  Quote: ... FAST-STEM hiPSCs grown to 80% confluency were dissociated into single cells using TypLE for 5 minutes and seeded into the Aggrewell at a density of 1.2×105 cells per-well in 1 mL of mTesR Plus with 10 μg/mL ROCK Inhibitor Y-27632 (Tocris Bioscience, Bristol, UK; 1254) and 1% Penicillin-Streptomycin (Life Technologies ...
• Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature

  Charlie J. Childs, et al., bioRxiv - Bioengineering 2024

  Quote: ... was obtained through the administration of exponential doses with concentrations of 1 nM to 10 mM at 2 min intervals before the administration of 10 μM scopolamine (Tocris Bioscience Cat#1414/1G). After another equilibrium period ...
• Probing PAC1 receptor activation across species with an engineered sensor

  Reto B. Cola, et al., bioRxiv - Neuroscience 2024

  Quote: ... to prevent recruitment of neuronal circuits that could lead to endogenous PACAP1-38 release (Tocris, biotechne; #Tocris 1262/50, #Tocris 0373/50, # Tocris0247/50, #Tocris 1248/50, #Tocris 1069/1).
• TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons

  Ki Bum Um, et al., bioRxiv - Neuroscience 2021

  Quote: ... glutamate and GABA receptor blockers (10 μM NBQX, Tocris, UK, 1044; 5 μM CPP, Tocris, 0247; 5 μM SR-95531, Tocris, 1262; 1 μM CGP-55845, Tocris, 1248) were included in the recording solutions.